Basic Information

Insect: Drosophila leontia
Gene Symbol: zfh1
Assembly: GCA_008042735.1
Location: VNKB01010086.1:11513-15762[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.4e-05 0.0021 18.5 1.0 1 23 153 175 153 175 0.97

2 15 0.00074 0.063 13.8 1.2 3 23 183 203 181 203 0.94

3 15 0.00024 0.021 15.4 0.2 1 23 367 389 367 389 0.98

4 15 0.00012 0.01 16.3 0.8 1 23 395 417 395 417 0.98

5 15 1.3e-05 0.0011 19.4 2.3 1 23 449 471 449 471 0.97

6 15 0.0012 0.1 13.1 0.9 1 23 505 527 505 527 0.94

7 15 0.035 3 8.6 0.7 1 23 533 556 533 556 0.93

8 15 0.024 2 9.1 0.4 3 19 565 581 564 582 0.95

9 15 0.00014 0.012 16.1 5.6 1 23 591 613 591 613 0.97

10 15 0.042 3.6 8.3 0.4 2 23 619 640 618 640 0.96

11 15 8.2e-06 0.0007 20.0 1.0 1 23 649 671 649 671 0.98

12 15 0.00093 0.08 13.5 0.1 3 23 679 699 677 699 0.97

13 15 5e-05 0.0043 17.5 0.5 1 23 705 727 705 728 0.95

14 15 0.033 2.8 8.6 0.3 1 23 738 760 738 760 0.97

15 15 0.005 0.43 11.2 0.2 1 23 1299 1321 1299 1321 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.4e-05	0.0021	18.5	1.0	1	23	153	175	153	175	0.97
2	15	0.00074	0.063	13.8	1.2	3	23	183	203	181	203	0.94
3	15	0.00024	0.021	15.4	0.2	1	23	367	389	367	389	0.98
4	15	0.00012	0.01	16.3	0.8	1	23	395	417	395	417	0.98
5	15	1.3e-05	0.0011	19.4	2.3	1	23	449	471	449	471	0.97
6	15	0.0012	0.1	13.1	0.9	1	23	505	527	505	527	0.94
7	15	0.035	3	8.6	0.7	1	23	533	556	533	556	0.93
8	15	0.024	2	9.1	0.4	3	19	565	581	564	582	0.95
9	15	0.00014	0.012	16.1	5.6	1	23	591	613	591	613	0.97
10	15	0.042	3.6	8.3	0.4	2	23	619	640	618	640	0.96
11	15	8.2e-06	0.0007	20.0	1.0	1	23	649	671	649	671	0.98
12	15	0.00093	0.08	13.5	0.1	3	23	679	699	677	699	0.97
13	15	5e-05	0.0043	17.5	0.5	1	23	705	727	705	728	0.95
14	15	0.033	2.8	8.6	0.3	1	23	738	760	738	760	0.97
15	15	0.005	0.43	11.2	0.2	1	23	1299	1321	1299	1321	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCACCACCCCGCTGCAGGCGACTCCTCCGAGACGGACATTATGGAGCACGAAGACGCCGACGGTGATGATATGGTGAGCGGAGCGGACGGCGACCCGGATGGGGACGGAGATGCGGATGCTGATCTAGACCATATGGCTGCCGAGAACCTGATCTTTATGGCGCGTGACGGCCAGCTGGGCGAGATTATCGCCGCCAACGAGGGAACCGTCCTGGTCACCGCCGATGGCACTACGGTAGCTTATGCGGAATCCTTCGACGACGATGCCCAGGTGGTCACCGAAGAGGTCATCACGGATGACTGGGTGCAGCACCAAGGAGCCGAGCGCGTGGAAATCGCCGCCGAACAGATAGCTGGCATCAGTAGCTCTCAGGAACTCTTGGACATGGAGCAGGATGAGTATACGGCTCTGCGACCCTATCCCTGCGACTTTTGCAGCCGCCGCTTTCGGAAGAAGGCCAGCTTGAACAACCATATGCTGGCCCACCAAAACGACCGACCTCATCTCTGCAAGCTGTGCGGTGCACGCTTCTCACGCCGAGCGGAGCTCATTAGCCACTTTAAGGCTCACGCTGAAGCTCAAGATGCTGCAGATGCCgaggcagcagccgccgccgcttcGGGCTCTTCCATAAAGTTCGAGAATCAAAGCCACAGGCAGATGGATGATCACTACTACGAGCAGGAGTGGCCGCTGtatcagcagcaacatcagcagcaggagcaggaacagcaacAGGATATAGTGCACCATGAGCAGATGCTGCAACAGGAACAACAGCAACTTGTCTGCAACAGTGAGGTCCAGTTTGTGGCCAGCTACACAGCATcggtggctcctcctcctgctccgtCGCGCGGAAGAATAAGCAGGCTAAAGCCCAAGGAGGAGAGCAGCCAGTTCATCGTAATTACCGATAAGCCGGCAGCCAGTGAGTTGCGGGACTACATGGCCAGTGAGCCGGTGCCTCAGCCAGTGGTGCCCACATCTCAGCCCATGGCCATTGATCCGCCGCCGGCACCGCAGCCAAACTTCCCGGTGCTGGACGACAGCAAGCCCTTTGTATGTCAACAGTGCGGATTGGCTTTTGCGCGGGAAAAGGCGCTGGTCTCTCACACAAAGAACCATCGCGTGGACTCGCCCTTTGAGTGCAACCAGTGTCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGACGCATCAGTTTGAGGAGAGCAACTCTGAGTATGATCCCGCTTCCGGCGAGGATAGCGCCAGCGAAACGTCGGAGCCGGAAGATCAGCTCTACGGGGAGTTCTACTGCAACGAGTGCGGCATCTCCTTCCATCGCCAGGATTTACTGCGACGCCATGCCAAGCAGCATTTTAAGCAGCAGGATCATCATTCGACGGTGGCGGCAGGCGATGGCAGCTCCTCGGACGTCATAGCTAGCGGGGATCAGGCCAAAGACGGTAATGACGGCCACTGTTGTCAAACGTGCGGTAAATCATTTCCCAGTGCCGCGGAGATGCTTTCTCACGCCGAAATCCATGCGAGGTTTCCTCCCTTCAAGTGCGTTCTTTGCggcataagtttctacgaggAGCAGGCCATCAAGCGGCACCTGCACGCCCGCCATCCCAACGAACTGAAGGCCAACTCCTGTGTGCTATGCGGTAAGGAGTGTCGCGACCGCAAGGCCCTGATCAAACATGCCTGGGATCACTCCCGCGAGAAGTGCCACTCCTGCTCCAAGTGCGGCAAGAACTTTCACAATAAGGCGCGACTGAAGCGGCACATGGCCTCCCACAGGGACAAGTCCGTGGTGTGCGAGGTCTGCCAGGAGGAGTTCCCCGACGGACGTACGTTATCTAATCACCGTCACTCGCATAGCACCACGTCGCCGGGCAAATTGTTTCCTTGCCACGAATGCGGCAAGACATTCGGATCACGCAGTTCCCAGCAGATCCATGTCCGCATCCATACGGGTGAACGTCCCTATGGCTGTCGCTACTGCTGGAAGGCCTTTGCCGATGGCGGAACATTGCGCAAGCACGAGCGGATCCATACGGGGGAGAAGCCCTACGCCTGTTCCGTGTGTCCGCGTGCCTTCAATCAGCGGGTGGTGCTGCGCGAGCACATCCGTTCCCACCACTCTGGACTGGATGGGGCGAGAAATACCTACCACTGCACAGTGTGCTCCGAGGATCTGGCATCCTCCAATGACCTCATACAGCACCTTATTCAGCACAGTGATTCGAACACCGCCAAACAGCGTCAACCAGTGaCGGGCCCGCGAAAGTACAAGCGTCGACGCAAGCTGCAGCCACACGAGATTGCACACATGCGGGCGGAACACAAGGATGCcaatggcggcggcgacgaGGAGGAGATTTTGGGTGCCGAAGGCAATGGCGATGGTGATGAGTATGCCAGCGATATCGACCTTTGCGACTTTGATGTTGAGAATGTGGATGATCTTTTTGAAATGGCCGAGTCGTCGCCCAAAAAAGAGAAGCGCAAGAGGGCATCGGCGGCGGCATCTGTAAAGACAGAGCCCAAACCTATTTCCAATGGCGGCGGATCAGCGGTGAAGCCTGTCCAAGAGAAGAACAAGGCCAAGCTGCGATATGACTCCACCAGCAGTCAGCAATCGGATCGAATTTGGGAGGAGAAGTTCCTGCAGGACAGCCAGGTGGCGCTCTTTCAAATCGATTCGCTGGTGGTGGTCAACGATACACATCTCCAGCCCGCTAGCTCAGCGGCCATGCCTAAGACGAGAGGTGgcgccaagcagcagcagcagcagcaggccaagcAGTCCGTTGAAAGAGCTGGCAACTCCAATCCCTCGGCTGCAAGCTCAGTTGGCACATCATCGGCCTCCGCCTCAACCTCTACATCCACTtccagcagtcgcagcaggaAGAAGACGGCAGCTAAAACGGCTGCTGCCTCACGACCCCGGATGATTCACACAGAGAAGACCAAGGTGCCGCCGGCCAAGGGAACTGCCGGCGGGGAGTTGGCCAAGAAGACTCGCTCCAAGACCTACATCACCCGCACGGAGACGAGCAATCTGAGCAGTCTGGACAAGTCGCGCAGCCGAGCCTCCAACATCGTGGATGACTACGAAATCATTTCACCGGCTACCCATCCTCCCAACCAGATCAGCTCCAGTCCCCTGCACATCAagcaagagcaggagcagcagcaccgtGTCCCGATGATGTACGACGACAATCTCCTGATAGACGCTGCCCTGCTGCGGGAAAAAACCTACGAGAAGTTCAACCCGAGCATTGTGAACGATCTGGAGGAGATCCTTCGCTCGCCGCTCAAGCACGAGCGCAACACCCGCCTGCGATTCACCAGCGAATCCTCGACAACGCCACAGTTTTTGCCCGAAGAAGAGCAGAATCTGATTAAGATCGAGCCCACGTCTCCGGATTTGCGGGAGATGCTGGAGAGTCAGAGTCAAAGGGTCAGGGTACCAAGTGGCAACACACCGTCGacctcatcctcctccgccgccagaACTTCTCGTCATCGTATGATCACAGCCAGTGGACCAAGAGCCGGGAACAAGAGAGGAGCAGGAAGTGGTAGCAGCGCTAGCAAATCTTCACCTGCCCCGGGAGTGATGGCCAAGAAAGTGAGCACTGCTGCCAGTAAGGTCGGCGGCTCGTCCTCGTACCTAAATTACGGTGTGGATGCCTACAATGTGAATGTACCTGCCAGCGCCAGCACTGCCGATGTGGGCAGCGGATTCTTTTCCATCTCGGAGGTCGTATCGGCCGCCGATGCTGCTGATGCGGCGGCCAAGGCGGCTGCGGCCGGGAAACCGGAGCGAAAAACCCGCAGTTTCGAGTGCGAAATGTGCTCGGCCATCTTTTATGATCGAGCCCAGTTACTGGACCATGTGCACATCCACATCTAG
Protein Sequence: MNNQDYGGIQWIQHHPAAGDSSETDIMEHEDADGDDMVSGADGDPDGDGDADADLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAASGSSIKFENQSHRQMDDHYYEQEWPLYQQQHQQQEQEQQQDIVHHEQMLQQEQQQLVCNSEVQFVASYTASVAPPPAPSRGRISRLKPKEESSQFIVITDKPAASELRDYMASEPVPQPVVPTSQPMAIDPPPAPQPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGEDSASETSEPEDQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQDHHSTVAAGDGSSSDVIASGDQAKDGNDGHCCQTCGKSFPSAAEMLSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHARHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDGARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDANGGGDEEEILGAEGNGDGDEYASDIDLCDFDVENVDDLFEMAESSPKKEKRKRASAAASVKTEPKPISNGGGSAVKPVQEKNKAKLRYDSTSSQQSDRIWEEKFLQDSQVALFQIDSLVVVNDTHLQPASSAAMPKTRGGAKQQQQQQAKQSVERAGNSNPSAASSVGTSSASASTSTSTSSSRSRKKTAAKTAAASRPRMIHTEKTKVPPAKGTAGGELAKKTRSKTYITRTETSNLSSLDKSRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRVPMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVPSGNTPSTSSSSAARTSRHRMITASGPRAGNKRGAGSGSSASKSSPAPGVMAKKVSTAASKVGGSSSYLNYGVDAYNVNVPASASTADVGSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -