Basic Information

Insect: Drosophila leonis
Gene Symbol: -
Assembly: GCA_035045365.1
Location: JAWNPC010000389.1:348730-365759[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 9.4 7.1e+02 1.2 2.5 3 23 315 337 313 337 0.93

2 15 3.7 2.8e+02 2.5 0.7 3 21 479 497 478 501 0.91

3 15 0.33 25 5.8 0.3 2 20 523 541 522 545 0.89

4 15 0.015 1.1 10.0 1.3 1 23 562 585 562 585 0.95

5 15 0.36 27 5.7 0.2 1 22 590 611 590 614 0.90

6 15 0.016 1.2 10.0 0.1 2 23 676 698 675 698 0.93

7 15 0.35 27 5.7 0.2 1 21 703 723 703 724 0.92

8 15 1.1 83 4.1 1.8 2 20 740 758 739 761 0.88

9 15 0.00012 0.0094 16.6 3.1 2 23 774 794 773 794 0.97

10 15 4.5e-06 0.00034 21.1 1.7 1 23 800 823 800 823 0.98

11 15 0.00018 0.014 16.0 2.2 1 23 846 868 846 868 0.98

12 15 0.0021 0.16 12.7 0.6 1 23 875 899 875 899 0.98

13 15 1.8 1.4e+02 3.5 6.4 1 23 904 928 904 928 0.95

14 15 0.0082 0.61 10.8 2.5 1 22 941 962 941 962 0.95

15 15 4.5e-05 0.0034 17.9 2.5 1 21 969 989 969 994 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	9.4	7.1e+02	1.2	2.5	3	23	315	337	313	337	0.93
2	15	3.7	2.8e+02	2.5	0.7	3	21	479	497	478	501	0.91
3	15	0.33	25	5.8	0.3	2	20	523	541	522	545	0.89
4	15	0.015	1.1	10.0	1.3	1	23	562	585	562	585	0.95
5	15	0.36	27	5.7	0.2	1	22	590	611	590	614	0.90
6	15	0.016	1.2	10.0	0.1	2	23	676	698	675	698	0.93
7	15	0.35	27	5.7	0.2	1	21	703	723	703	724	0.92
8	15	1.1	83	4.1	1.8	2	20	740	758	739	761	0.88
9	15	0.00012	0.0094	16.6	3.1	2	23	774	794	773	794	0.97
10	15	4.5e-06	0.00034	21.1	1.7	1	23	800	823	800	823	0.98
11	15	0.00018	0.014	16.0	2.2	1	23	846	868	846	868	0.98
12	15	0.0021	0.16	12.7	0.6	1	23	875	899	875	899	0.98
13	15	1.8	1.4e+02	3.5	6.4	1	23	904	928	904	928	0.95
14	15	0.0082	0.61	10.8	2.5	1	22	941	962	941	962	0.95
15	15	4.5e-05	0.0034	17.9	2.5	1	21	969	989	969	994	0.93

Sequence Information

Coding Sequence: ATGAACTCGCAATCGGATGATCTGGAAGATGCGCATCTGTGCATTAAGTGCAATGCCACAATTGTGGGTCTGCGCAAATACATTGATCATCGCAAGCAGAATTGTCTGAGCATTGTTGGGAATGCTCGCAAGGGGAAGCAAGCTGTGGCTACGCCGCATGTGACGTCTACAGTCATAACTCGCTCCCAGTTGGCACATAGCTATGATAGCTTTCACTTCGCGGAGCCGGAAGCGCCGAGCAGTTACTTGCGCAAGACGACGGCCAGTCATGGCGGCAAGACGTCCAAGGCCCTAACTGAGGCCTATGATCCGACCTATGAGCTGGGCGCCGATGTCTTCTTTTcgtcgctgcagctgcagagtGTCTCAACGGGCGGCAAGACAGGTGCACGGCCCGAACGTGGCGCTAAGGTGGGACAGAGCTGGGATTCAGCCAGCAACTGCTCCGATCCGTTGCTGAAGGCGGTGCGGGAACATGAGGAATCCAACTTTAAGACACTCAATTTTGTGCACTCGCCCGAGGCAAGCGAGGACGAGGAAGATGACGAGGAGGGCGATGACTTTGAtggcgatgatgatgaagcAGATCAGATGCAGGAGCACGAGCATGAGCATGAGCATGAGCATGAGCAGGAGCAGGATCCAGAACATGATCCCGATCCTGATCCTGATCCTGATGAAGATTATGATGCGCGACGCCACTCGCCGCCAGCTGTGCCTGCTACGCACACAGGCGGCAAATGGCGGCCGGAGCAGCGGCCACAGTTGCGTCACACGCATCTGGAACGCCTCTCGCCCAGCTGGGATGAGCCGCCCGAGGATGCACACGATCACCCACCCGCCGAGCATACACACGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGCGAAAACATTGATCTGaccaagctgcagcagccggaCGCCAGCTATTGGTGCAACATCTGTTGTCGCCGCCTCAAGACGCGCCTCAACTACGATCAGCATCTGCGCACGGTCTATCATCAGCGGCGCGCAGAGCCCGAGTCCCAATTGGAACAGGCCAATCTGGAGTCCGCCAATCTGACGCTCAACACGAACTTTGCCCAGCCGCCGGCACCAGCCGCAGAGCAAAGGCagcgacgtcgtcgtcgtcgtcctgcCCGTCTACGCTGCGAGCTGTGCCGCAACAGCATGGCGCGCCATCTCATCGGCAAGCATCTGATCTCCCACTATCACTATCGacgcctgcagcagcagcaaaagacaCAGCTGGGCAGCCAGAGCTACCTGCACGCCATACTGGAGCACATGGGCAGCATTGTGCGACAGGCGCCATTCCAGTGTCTGCCCTGTCGATTCTATGCCAATACAGAGCAAACCTTTCAGGCTCATTGGCGTTCGCCTGCTCATATCGAGCTGACCAAGCAGCTGGGCGGCAGTTTCTGGTGCAGCTACTGCCAGTTCGAGTGTGGCAGCAACGAGGAGATGTGGCAGCATCTTCTGGGCAATACGCACATGGAAGTGCTGCTGGCGATCAATCGATCGGTGCCCGTTTACATTGCTCAGCGGCGACATCTGAGCTGTTCCGTGTGCAAGGCCAGCTTTCTCTACAATGTGCAGTTGCGGCGACATTTCGGCGCGGAGCATGCAGGAGTGGCGAGCACGGGCAGCGCCTCGGATGACTATCAGTGTCGCTTTCGCTGTGAAATTTGCGGAACTGCGCAAAGATCGCGCGTGGCACTGCAGCGGCACGAGAAGCACAAGCATCGAGTGAGAAAATATTATTGTGCCGTTTGTCAGCTGGAGTTCGAGACGTCGCTGGCTGCTCGTCGGCATCGCAATCTGTTGCAGCATAAACAACATGCGAATCGTTGTCGGAGCAGTGGCAAACGCAGAAGCTCTGAGCAACAGAAGCCGCCGGCGCAACCGGATGAGGAAACTGAAATTGAGCATATGCTGCGCGAGGTGCTGGAGGAGCCGCAGGCTGAGCAGCCAATAACCAAGCCGAGCTTGGTTAAGAGTCCGCCCTCAGTTAGCCAATGCGTCAATTGCCAGCTAAGCTTTGAGACGGCCCAAGCGCTGATTCAGCATCGCAGCGAAGCACATCCCAAGGAAAATCATGCATGTCTcagctgtggcagcagctTTCAGAGTGCCCAGGCTCTGGGACGGCACACGCGCAGCTGCCAGCCCACTGCCTCGACCACCTCGACAGCTACGTCGGCCTGGCAGTGTGATCAGTGCGGCTTCTGTACCCAATACGAGTCTGATCTACTCTATCATGGCTTCTTTCACACACGCGGCTCATCCATTGGCAAGGACGAGCTGCTGCAATGTCCGCGCTGCCCCAAAAAGTTTCGCAAGCACTCGCTGCGTGCCCATCTGCGCAATCACACAAACGAACGCATCTTCGAGTGTGGCCAGTGTCCGACCAAGTTCGCCAGGCGACACAATCTCAAGACTCACATTAACACCATACATGGCCAGCGCAAGAAGACGAAAAAAGACGCCAAGGCTACGGCTAAACAGGCGACGAAGCCCATCGAATTCCAATGTGGAAAGTGCGacaaaaaatatgctaaaaaattttcacTGAAGATGCACGAACTGACCCATGGCAAGAGGAAGCCTCTATACTATTGCTCCAGCGAGGACTGCTCCTATTCGGGTATCACGAAGGACGGCCTGAAAACCCATCTGAAAACCCACGCCCAGGGCAAACACAGATGTCGACTCGAGCACTGCAGCTATGTGGGCAAAAGTGATCTGCACTTGAAGCGGCACCTCAAAACGCATTCACGTAAGCTAAATCTGGCTGATGGTGGCATATGGTTCACGTGCGATCATTGCGACTACAAGACACGAAGCAAGAGTCTCCTGAATTTTCACATACGCCGAAATTGCGACAAGAAGCCCCATAAATGTCCCCACTGCGACTACGCGAGCAGCAGCTCCGACAATCTGCGCAAACACATCATTCGGACGAGAAAACATCCAGGCAAGTTCGTCTACGAGTGCTCGACCTGCAACACATTTAAGAGCAACAGCTTTAAAGACTATCAACAACATTTGGTAACGCACAAGAGGAAGGCTCGTTGA
Protein Sequence: MNSQSDDLEDAHLCIKCNATIVGLRKYIDHRKQNCLSIVGNARKGKQAVATPHVTSTVITRSQLAHSYDSFHFAEPEAPSSYLRKTTASHGGKTSKALTEAYDPTYELGADVFFSSLQLQSVSTGGKTGARPERGAKVGQSWDSASNCSDPLLKAVREHEESNFKTLNFVHSPEASEDEEDDEEGDDFDGDDDEADQMQEHEHEHEHEHEQEQDPEHDPDPDPDPDEDYDARRHSPPAVPATHTGGKWRPEQRPQLRHTHLERLSPSWDEPPEDAHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPDASYWCNICCRRLKTRLNYDQHLRTVYHQRRAEPESQLEQANLESANLTLNTNFAQPPAPAAEQRQRRRRRRPARLRCELCRNSMARHLIGKHLISHYHYRRLQQQQKTQLGSQSYLHAILEHMGSIVRQAPFQCLPCRFYANTEQTFQAHWRSPAHIELTKQLGGSFWCSYCQFECGSNEEMWQHLLGNTHMEVLLAINRSVPVYIAQRRHLSCSVCKASFLYNVQLRRHFGAEHAGVASTGSASDDYQCRFRCEICGTAQRSRVALQRHEKHKHRVRKYYCAVCQLEFETSLAARRHRNLLQHKQHANRCRSSGKRRSSEQQKPPAQPDEETEIEHMLREVLEEPQAEQPITKPSLVKSPPSVSQCVNCQLSFETAQALIQHRSEAHPKENHACLSCGSSFQSAQALGRHTRSCQPTASTTSTATSAWQCDQCGFCTQYESDLLYHGFFHTRGSSIGKDELLQCPRCPKKFRKHSLRAHLRNHTNERIFECGQCPTKFARRHNLKTHINTIHGQRKKTKKDAKATAKQATKPIEFQCGKCDKKYAKKFSLKMHELTHGKRKPLYYCSSEDCSYSGITKDGLKTHLKTHAQGKHRCRLEHCSYVGKSDLHLKRHLKTHSRKLNLADGGIWFTCDHCDYKTRSKSLLNFHIRRNCDKKPHKCPHCDYASSSSDNLRKHIIRTRKHPGKFVYECSTCNTFKSNSFKDYQQHLVTHKRKAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -