Basic Information

Insect: Drosophila leonis
Gene Symbol: L
Assembly: GCA_035045365.1
Location: JAWNPC010000110.1:11161679-11170924[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00081 19.9 2.9 1 23 164 186 164 186 0.98

2 17 0.37 28 5.6 6.2 1 23 192 214 192 214 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 220 242 220 242 0.99

4 17 1.3e-05 0.00099 19.6 0.4 1 23 248 270 248 270 0.99

5 17 0.015 1.1 10.1 0.2 2 23 349 373 348 373 0.93

6 17 0.00032 0.024 15.3 0.2 2 23 405 427 404 427 0.96

7 17 0.065 4.9 8.0 0.7 1 23 491 513 491 513 0.97

8 17 0.054 4 8.3 0.4 2 23 521 542 520 542 0.91

9 17 0.022 1.6 9.5 1.2 3 23 553 575 550 575 0.86

10 17 3.4 2.6e+02 2.6 1.0 2 23 611 633 610 633 0.95

11 17 0.0027 0.2 12.4 1.1 1 23 676 699 676 699 0.97

12 17 0.0068 0.51 11.1 1.6 2 23 870 892 869 892 0.96

13 17 0.12 9.1 7.2 0.1 1 23 898 920 898 920 0.92

14 17 0.58 44 5.0 0.4 2 23 928 949 927 949 0.93

15 17 0.33 25 5.8 1.3 1 23 1051 1073 1051 1073 0.94

16 17 0.02 1.5 9.6 0.0 1 23 1083 1105 1083 1105 0.96

17 17 0.00023 0.018 15.7 1.2 1 23 1110 1132 1110 1132 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00081	19.9	2.9	1	23	164	186	164	186	0.98
2	17	0.37	28	5.6	6.2	1	23	192	214	192	214	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	220	242	220	242	0.99
4	17	1.3e-05	0.00099	19.6	0.4	1	23	248	270	248	270	0.99
5	17	0.015	1.1	10.1	0.2	2	23	349	373	348	373	0.93
6	17	0.00032	0.024	15.3	0.2	2	23	405	427	404	427	0.96
7	17	0.065	4.9	8.0	0.7	1	23	491	513	491	513	0.97
8	17	0.054	4	8.3	0.4	2	23	521	542	520	542	0.91
9	17	0.022	1.6	9.5	1.2	3	23	553	575	550	575	0.86
10	17	3.4	2.6e+02	2.6	1.0	2	23	611	633	610	633	0.95
11	17	0.0027	0.2	12.4	1.1	1	23	676	699	676	699	0.97
12	17	0.0068	0.51	11.1	1.6	2	23	870	892	869	892	0.96
13	17	0.12	9.1	7.2	0.1	1	23	898	920	898	920	0.92
14	17	0.58	44	5.0	0.4	2	23	928	949	927	949	0.93
15	17	0.33	25	5.8	1.3	1	23	1051	1073	1051	1073	0.94
16	17	0.02	1.5	9.6	0.0	1	23	1083	1105	1083	1105	0.96
17	17	0.00023	0.018	15.7	1.2	1	23	1110	1132	1110	1132	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACTTCATCGAGCTACTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAATTCACAGCTgcaacagccgcaacagcagcagcagcagcaacagcagccacagcctgGCGAGGAGGCGAGCGAGGAGGCCAAGGCGAATGGTGATGCTGTGCAGCAAACGGAGCTCGAGCAGGAGTTGAGCAAGCCGAAGCGACCTGCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATAGCGAACAAACTGCGCAAAATCAATAAGGATGCAAAACTGGCTGcaggacaaggacaaggacatGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCGAAGCTCTTCAAGCACAAACGCTCGCGAGATCGTCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTATAACACGGCCGCCGCCCTCACCTCCCACATGCAAAAGCATAAGAAGAATGCCGCAATCCTGGCCGCTGGCGGCAATCCCAATGCACTCAACTATAGTCCACGCTCCACGGGCTCTGCCTCCATATCGAGCAATGGCAGCTTGCATAAGCGTCGCTATGCCTTGGCGCTGGCCTCCGATAGTAGTCCCAGTCGCTTGGAGTTTCCCAAGCGGGCGCGTGGTCAGTTAACGGCCACGCCCACGGCCACAACcatagccacgcccacgccgcTGCTGCGCTGCAGCTACTGTCCCAAGGCAACGGAGTTTAGCAGTCTGGAGCAGCTCAATGCGCATCTGCAGAGCAcacacgagcagcagcagcagcagcagcaacaaccgcagcaacagcagcagcagcagcagcaaaaggatGCGGATGGCCAGACAAATGGTTTCCAGTTGAGCTGCGAATATTGCACGATGAAATTTGTGAATATCGCCGCGCTGTTCCAGCATATGAGAGTGACGCACTTGGATCGTCTGAGCAGTCCCAACTCCTATTACGAGCACTTCAATCGCCTCGGCTCGCCGCAGTCGAAGATCAAAGCGGATCTGGCGACGTCGGAGAAGCCCGAACAGGAGCTGCCCACCGACTTGAGCAGCAACAAGCGACGTCCGCTGACATCGCCCACGCAGGCGCCGCCTGCCCCGCCGGGCATCTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTCGAGAGCTTTCGCAATCATCTGAAGAGTCACATAGCCGAGGGCATGCAGCTGATCTGTCCGCACTGTGGCCTCAGTCTGCCCGAGCAGTGCGAGTTCGAGCGTCACGTGGTCGCTCACTTCTTGATCAGCAGCTCCGAGTTCAATTGCTGCAGCGCCAGCTGTGGCAAGTCCTATGCCAAGGCTGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTGCAGACCATGCTCAAGTGTGCCCTGTGCTCCGAGCTGTGCGAGAATCGCATGTCCATGCAGCTGCACTTGGCCTGTGCGCACAGTCAGGAGTCGAAGCTGCTGCGATGCAGCGCCTGCCTGGAGCTGTTTCGCAACGATGGCGACTTCCATGTGCATGTGAAGACACGCCATCAGCTGGGCAATCAGGGTCTGGGCAATCCGCCAGCTCCGGCCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTCTGCTCGTCGGAGCTGGAAATGCATTTCCATTTGGCGGCGCATGCGCGACAATTCCGCTGTCCCAGCTGCCCGGAAACGTTTCATGTGGAGTTCCTGCTGGACAGGCACATGCAGAGTCAGCATGGCGGCATCAAGGACAAGGAGTCGCCTGTGTCAGGCGGCATGGGTAGTTTGTATGTGAATGCATTGCTGCCGCctttggctgcggctgctgcagccgctgctgcagcaaacaatgccaacaacaacaacaacaacaatagcaacctGCACATAGACTACAATGTCGCCTTCAAGGGTCTCTTTGGCGGCAACAATCCGCCGAGCAAGTTCTACAACAGTCCACTCCAAGTGGACACCAAACAGAGTCCACACCCAGCCCTGATGTACGGCCTGAGCCAGCGCTACTTGATGGAGATGTACGCCGCGAAGGCCAACTCGCCAGCCAATGCCAGTGCCGTGGAGCTGGCCACGCCTCAGGCTGCTCAATCCTCGGCAGCGGcgagtggcagcagcagcaacagcaacaacagctacagctgcggCATGTGCGAGCGCCAGGATTTGCGCAGCGAAGCCGAGCTGCATTCGCATCGGAAGCTCGCGCATAATCTGAAGACGGGCGTCAGTCTGCGCTGTGCCTATTGCTCGGGCAACTACAAGAGTCGTgcggagctggagcagcacaTGAAGAGCTGCCACAATTCCAGTGGCAAGCACAAGTGCCTCATCTGCGACGAGATCTTTCCCTCGCCGGCCATACTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGCAAGTGTGCCCACTGCggccagcagctggagcatgTGGCCGCCTTTCGTGCCCACCTGGGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGTATTTGTTGCCGCCAAACCCTCCACTCGGAATTCGAGCTGAGTTTGCATGCCAAATTCCATACCAAATCGCCCAGTTGCAATAGCCTGCAGGAGCCCGTTTGTGCCCTGTGCCTGGAGCCGCTGCCCGGCGCCGGCGAAACCGCCAAGTTGTGCGACAAATGTTGCCGCAAACACAATCTGAATGGCAAGCGCAAGGAGCAGCAAGtgcagccaacagcagctccagctgccgctgctgttgcagttgccgtgGCAGCTAGCGCCTATCTGGAGCATCGCTGCAATCTGTGCAAAATGATCTTGCCACATGCCCAGAAGCTGCAAGAACATCTCGTCGAGCACACGTTTGCCGGCACCGAGCAGCGCGGCTACAACTGCTACATCTGCTCGGCCGTGTTCACGGCACCAGGTGGGCTGCTCGCCCACATAGCGGAGCATGGCACGCGTCCGTATGATTGCAATTTGTGCCCGGAGAAATTCTACTTTCGTGCCGAGCTGGAGCATCATCAGCGCGCGCACGAGCTGCGCCCACAGCCGATAGCACGACCCAAGCAGGAGACGCACAGCTCGACGGCCAGTTCGCCTCTGACGCTCAGTCCCAGCCATGTTAAGCAGGAGCTATACGAATCGGAGCCAGCAAATTCGCCTAACGCCGCTGAGCAGCTGCCCGCGCAGCCGGAGGAGGAGGAATATATCGAAGTGGAGCAAGTGCCGCAGGAGACGCTGCGAACTGGCGAACTGCTAAGCACCGAGCgttccagcagcagcgcctaA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQQQQQQPQPGEEASEEAKANGDAVQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTATPTATTIATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQQQQQPQQQQQQQQQKDADGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKIKADLATSEKPEQELPTDLSSNKRRPLTSPTQAPPAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEFERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCALCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDGDFHVHVKTRHQLGNQGLGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVSGGMGSLYVNALLPPLAAAAAAAAAANNANNNNNNNSNLHIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANASAVELATPQAAQSSAAASGSSSNSNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQQVQPTAAPAAAAVAVAVAASAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRPQPIARPKQETHSSTASSPLTLSPSHVKQELYESEPANSPNAAEQLPAQPEEEEYIEVEQVPQETLRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00502755;
80% Identity: -