Basic Information

Insect: Drosophila leonis
Gene Symbol: -
Assembly: GCA_035045365.1
Location: JAWNPC010000110.1:16961996-16967058[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 5.7 4.3e+02 1.9 8.3 2 23 354 376 353 376 0.96

2 17 0.0077 0.58 10.9 1.6 2 23 419 440 418 440 0.94

3 17 6 4.5e+02 1.8 3.0 2 17 451 466 450 477 0.75

4 17 0.065 4.9 8.0 0.8 3 23 510 530 508 530 0.95

5 17 0.0039 0.29 11.9 0.3 1 23 538 561 538 561 0.97

6 17 0.00045 0.034 14.8 0.3 2 23 566 587 565 587 0.97

7 17 3.6 2.7e+02 2.5 0.0 2 20 596 614 596 615 0.90

8 17 0.00011 0.0079 16.8 0.4 1 22 635 656 635 659 0.90

9 17 0.066 5 8.0 0.6 1 21 664 684 664 685 0.93

10 17 0.013 0.98 10.2 0.6 1 23 704 729 704 729 0.96

11 17 0.04 3 8.7 1.4 2 23 745 767 744 767 0.93

12 17 0.0024 0.18 12.5 0.1 3 23 774 795 772 795 0.92

13 17 0.025 1.9 9.3 0.4 2 23 799 821 798 821 0.96

14 17 2.8e-05 0.0021 18.6 2.2 1 23 827 849 827 849 0.98

15 17 0.021 1.6 9.6 0.6 1 23 853 876 853 876 0.94

16 17 7.7e-05 0.0058 17.2 0.8 1 23 882 905 882 905 0.97

17 17 0.00054 0.04 14.6 0.7 1 23 909 937 909 937 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	5.7	4.3e+02	1.9	8.3	2	23	354	376	353	376	0.96
2	17	0.0077	0.58	10.9	1.6	2	23	419	440	418	440	0.94
3	17	6	4.5e+02	1.8	3.0	2	17	451	466	450	477	0.75
4	17	0.065	4.9	8.0	0.8	3	23	510	530	508	530	0.95
5	17	0.0039	0.29	11.9	0.3	1	23	538	561	538	561	0.97
6	17	0.00045	0.034	14.8	0.3	2	23	566	587	565	587	0.97
7	17	3.6	2.7e+02	2.5	0.0	2	20	596	614	596	615	0.90
8	17	0.00011	0.0079	16.8	0.4	1	22	635	656	635	659	0.90
9	17	0.066	5	8.0	0.6	1	21	664	684	664	685	0.93
10	17	0.013	0.98	10.2	0.6	1	23	704	729	704	729	0.96
11	17	0.04	3	8.7	1.4	2	23	745	767	744	767	0.93
12	17	0.0024	0.18	12.5	0.1	3	23	774	795	772	795	0.92
13	17	0.025	1.9	9.3	0.4	2	23	799	821	798	821	0.96
14	17	2.8e-05	0.0021	18.6	2.2	1	23	827	849	827	849	0.98
15	17	0.021	1.6	9.6	0.6	1	23	853	876	853	876	0.94
16	17	7.7e-05	0.0058	17.2	0.8	1	23	882	905	882	905	0.97
17	17	0.00054	0.04	14.6	0.7	1	23	909	937	909	937	0.88

Sequence Information

Coding Sequence: ATGTCGGGAAATTCGAAAATAAACAACGAAAATGGGCCTAGCTGCCTGCATTGCAGTGTGGTCAATTCAAAGCAATATCAAGAAATTTTCGACGAAGTGGGCATCGAAATTGAACTCCCCGAACTGTTAGCCAAATATTTCCAGCTCATTGTCAAAGCCGATGCACAAAAGTCACAATTGCTATGCCTAGAATGCGTTAATACGCTAATACGCTTCTTTGACATAGACGAACTGCAACGTGAGCAGGATGCCGCCAATGCGCGCAAGaaggccaagcagcagcagcaggagaatTCTGCCAAGGTTGAAAAACCTGTCAAAAAGGAGCCGTCGCCCAAGGCAAAGAGCGCCACAGTTGCAGCTAAAAGTGTGCCAACGCCTGTTAAAGCAGTGAagccagcaacagttgctgtcgctgctgctcccgctcccgctgctgttgttgctataacTGCACCAAAAGCCGCTCCAGCAACTGTAGCCATACGCATCACCAGAGCCCGTTCCGTTGCGCCCAAGCGCTTGTCCGCGAAGGCTAAGCAGGCAGTTAAGCCAAATGCCAAAGTCAAAGTGAAAAGTAATGGTTCGGCGGATCAGGAACAGATTAGCGCACTCATACGTGACATACTCGATGATGAGGAGGCGCCGCCAGGTGACAAATTTGCTGAGGCCGCCGCCACGGTGCGGCAGCTGGAAAAGCAAACGAACAAAAAGCAGCGACAACTCAAAGTGGAGGAGACTGAGGAGCAGCTGCAGGAAGACGAGGATAACAATGAAGAGCTGGAGTTTCTGTTAGAGCCAGAAGACAACTCCTCCGATCTGGATGTGCGCAATTTCAAAGTGGAACGCAAAGTCAAGCGCGCTGCTACGCGctcccaatcccaatcccaatctCAATTCCAATCGCAAAATGAAAGCCCAAGCGAGGATGAATCATTAAAAGTGGAGCCTTTTAACTTTGTCTTAATCAAAGAATCTGACAACATTGGCGATCTGCACGAATATCTAGCGACGGTGGTCAAGACCTGCTTTGAGACCTTGCAATTCGATTGGGCCACTGTCTGCCGGCATTGTTCGTTGAAATGCAACAAATATGAAACTTTGCTCAGTCACATGCAGAAATGCCATCAGCTGGCAGATGAACGCTACAATTGTCCCATTGAAGGCTGCATTGCGGAGCTGCATGGACGCAAATATTTGGCCATGCATTTGGTGGTGCTGCATGCACCTGTGGCAGAAATACCCATCTATGGCAAGTGTCCCGAGTGCAATATGACCTTCTCCAATATCTTGCAGTACAACAAACACTCCTGCGCGCACGTCATTAAAAAGCGGCGCGGCATACGTTTATACTGTGAGATGTGCGGCTTGGAGTTTCCCTCGTGGAAGCGCTTTAATTTCCacaatcaatttcatttggaGCGTCACAGACCGCGCGCCTGCTTCGTTTGTAATTTTGCGGACAACAACATCGATGAGCTCTTCCATCATTTGCACTATGCCCACGAGCCCGAGGGCACACTCTTCTGTGATCTCTGTGATCGCAACTTTCGAGATGATTCCGTTTTTATGGAGCACAACAAATCGCATGCAAATGTCAGCAGCACCACCTTCAGCTGCTCCGAATGCAGCGCCAACTTTGAGACACGCGGACGCCTCAACGGTCATCTGCGCTCCGTTCATGGCAGTGTTATCAGCTGCGAGCTGTGCAGTCGCGAGTTTGCCACAGAGGCGACCTACAACTTGCACATGAAGACGCATCTAATCATTGAGCGTGAGGTGAACGTGTGCAATGGCTGTGGACTGCTCAGCGAGAATAACCAGAAGCTGCTGGCTCATGTGGAGGCAGAGGAATCAGCTTGCCTTGGCATGGACACCTATGCGGAAGTGTTACGCAATGCGTATGTCTGCGAATATTGCTCTGCCTACTTCAAGCAGAAGAGCGATTTGCGTGCTCATCGCGATTCGGGCGTGCATAAGGATGGCCTATTCATATGCCAGCCGTGTGACAAGGAGTTTGCCGACATGAAACTCTATCGCCATCATTTGCGCAACTTTCAGCAACAGCGCTCAGATGTGGCGCATCGCAAGCTAGAGATATGTATCTACTACATGTGCGACTATGAGaaCTGCACTGAGGCCTACATTAACTGGAACTCGCTGTACACGCACAAGCGGCGTTCGCACGATGCTGTCGTCAAGCAGGAGCCGCAAGCCAAAGACCATGAATGGATCTGCCAGTTCTGTCAGAAGCAATGTCGTTCCAAAATGTCGCTATCGGTGCATGTGGCGCGTGGTCACAACAATAACAATGTTATATGCCCGCTGTGCAAGGCCTCCTATAAGGATAACGATGCATTGGCCAAACATCATGCCTATTGGCATGAGCCCATGGAGTGTCGTCTGTGCCTGAAAGTGGTTAAAAATCGTCGCAACTATGATACACACATGAATGTGGTGCACTCGAATAACAAACGCTACTCGTGCAGCTTCTGCCCAAAGGGATTCTATCATAAAAGTGAAATGGAGGCGCATCAGCGGCTGCATAGCCAATCGTACAGCTGCGAACAGTGCAGCTTCATAACACGGAACAAGAAGTCGCTGTCGGTGCATGTGATGGGCCAGCATTACAAACGCTTCGCCTTCGAGTGCAAGGCGTGCGACAAGCGTTTCGGACGTCGCCAGGGCCTATCGAATCATATGCAACGCGTGCATGGCTCCAGGTATACGTGTCGCGATTTCTTCGATGATGGATGCAGCAAATCCTTTAGCTCAACGACACAGCTCAATATACATGTGCGCAAGGCGCATAATGGCAGCGTTTACCTGGAAGATGAGACGACTAAGGGCGAGGAACTAGatgaggaagaggaggaggaggagcaggagcagcagcaggaggaagTGACCAGCGATGGTCCGTCGTCATCGAAGAAACGCTGTATACGCATCAATGCGAATACACAAATCGAGTTTATCAGCGACTCGTCGGCTGTGGCCGAATATAATGAGAGCATGGACAGCTCCGAGATGTTCGAGGAGTTCAAGGAGCTCAAGCATGTGACAGAGTCGACACCGAAACTGAAGCAAAGGCAGAATTAA
Protein Sequence: MSGNSKINNENGPSCLHCSVVNSKQYQEIFDEVGIEIELPELLAKYFQLIVKADAQKSQLLCLECVNTLIRFFDIDELQREQDAANARKKAKQQQQENSAKVEKPVKKEPSPKAKSATVAAKSVPTPVKAVKPATVAVAAAPAPAAVVAITAPKAAPATVAIRITRARSVAPKRLSAKAKQAVKPNAKVKVKSNGSADQEQISALIRDILDDEEAPPGDKFAEAAATVRQLEKQTNKKQRQLKVEETEEQLQEDEDNNEELEFLLEPEDNSSDLDVRNFKVERKVKRAATRSQSQSQSQFQSQNESPSEDESLKVEPFNFVLIKESDNIGDLHEYLATVVKTCFETLQFDWATVCRHCSLKCNKYETLLSHMQKCHQLADERYNCPIEGCIAELHGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNFADNNIDELFHHLHYAHEPEGTLFCDLCDRNFRDDSVFMEHNKSHANVSSTTFSCSECSANFETRGRLNGHLRSVHGSVISCELCSREFATEATYNLHMKTHLIIEREVNVCNGCGLLSENNQKLLAHVEAEESACLGMDTYAEVLRNAYVCEYCSAYFKQKSDLRAHRDSGVHKDGLFICQPCDKEFADMKLYRHHLRNFQQQRSDVAHRKLEICIYYMCDYENCTEAYINWNSLYTHKRRSHDAVVKQEPQAKDHEWICQFCQKQCRSKMSLSVHVARGHNNNNVICPLCKASYKDNDALAKHHAYWHEPMECRLCLKVVKNRRNYDTHMNVVHSNNKRYSCSFCPKGFYHKSEMEAHQRLHSQSYSCEQCSFITRNKKSLSVHVMGQHYKRFAFECKACDKRFGRRQGLSNHMQRVHGSRYTCRDFFDDGCSKSFSSTTQLNIHVRKAHNGSVYLEDETTKGEELDEEEEEEEQEQQQEEVTSDGPSSSKKRCIRINANTQIEFISDSSAVAEYNESMDSSEMFEEFKELKHVTESTPKLKQRQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512900;
90% Identity: -
80% Identity: -