Dleo004379.1
Basic Information
- Insect
- Drosophila leonis
- Gene Symbol
- ZBTB40
- Assembly
- GCA_035045365.1
- Location
- JAWNPC010000202.1:8237488-8238908[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 4.3e-06 0.00032 21.2 1.1 2 23 12 33 12 33 0.96 2 11 0.0013 0.098 13.4 3.9 1 23 39 62 39 62 0.91 3 11 2e-06 0.00015 22.2 0.6 1 23 151 173 151 173 0.98 4 11 7.9e-05 0.006 17.2 2.0 1 23 179 202 179 202 0.95 5 11 0.021 1.6 9.5 2.3 1 23 208 231 208 231 0.87 6 11 0.2 15 6.5 3.3 1 19 236 254 236 257 0.84 7 11 0.19 14 6.5 6.5 1 23 280 302 280 302 0.96 8 11 3.5e-06 0.00026 21.5 3.4 1 23 314 336 314 336 0.97 9 11 6.7e-05 0.005 17.4 7.8 1 23 342 364 342 364 0.98 10 11 9.6e-06 0.00072 20.1 0.3 3 23 373 393 371 393 0.96 11 11 4.8e-05 0.0036 17.9 1.5 1 22 399 420 399 423 0.92
Sequence Information
- Coding Sequence
- atgaaaaatgttgacAAATTGGCAAGTTTAAACACCTGTGGTACATGCGGAAAGTGCTTTTCCAAGCCTGCATTACTGCGCCGTCATCTGGTTGTGCACAGCACTGAAAAAGCATTTCCATGCGCAAGCTGCTGCAGTCGCTTCTCTCAAAAGAGCTCACTGCAACGTCACATGCGTATGAAACATGATGTGGCCAAGGCCGAGGAGTGCGACGATTCCGATGTGGCGCAACACGCGCTGGCTGCCCTGAAGCTGCTACAAGGCAGTCATACGACTACAGCTAATGCAATTGCAAGCCATaagatagcagcagcagcagcatcgtcAGGCACTCTCGAGGAGGAAGTATCTTGTGATGTAGTAGAACTAAGAGACCAACTCAATCCAGCTGGTGAAGTCCATATGCTCGTCACACAGCGCATACGGCGACAGAGCCCCAACAGCTGCTACTATGTGTGTGAATATTGTGCTAAAGAGTTCAGCAAGAGCTACGATCTGATCAGGCATCGTCGCGCACACACCAAAGAGACTCCCTATCTATGCAGTAAGTGCCTCAAGCGTTTTGCCACGCGAAGCAAGCTAAATGAGCATCTCAAGCGTCTGCATGCTGCTGTGAAAAAGCATGCATGCAGCGTGTGCATCTCCAGCTTTAGCTCCAAGAGTCAGCTGCACAGGCACCTGGGTGAGCAACATGCCGATATGGTCTATAGCTGTAGGCACTGTAGTCGCACTTTCCAAACGAAATCTGCCTGTGACGCACACACGAAACTAGAAACAGATCCGCTGAGGCGAAATCTCCTGGAACTGTTGCCACAGCCAGTGCTATCGCAGCGCAGCTTCAAGTGCATCTACTGCAAAAAGCAATTCGAACGCAAATTCAACTGCCGCACAcacatgttgttgcatttgcggCGTTTGATGGATACAGAGCAGCTGAGACATAGTTGCCTCCAGTGTGGCAAGCACTTCAAGAGACCCAACGACTTGGCCCGACATTTACTAACACATTCCAAGCTTAAGCTGCACAAGTGTCACGTGTGTCAAAGATGCTTTACCCTAAAGTCCACATTGGCCAGGCATTTAGAAACGCATCTGCCACAACGGAGCAGTGTCAATTGTCAGGTGTGCGGCAGGAGCTATGCCTCCAAGAcatcgctgcagctgcatctgcGCTTGCACACCGGCGAACGACCCTTTAAATGTGAAAGATGCGGTGAAACCTTTCGTACGTCGGGACACAGACTGGAGCATATGCGAGCCGAACGGCACAAGAATGCATCGTCCCATGCACTCATTCTTTGA
- Protein Sequence
- MKNVDKLASLNTCGTCGKCFSKPALLRRHLVVHSTEKAFPCASCCSRFSQKSSLQRHMRMKHDVAKAEECDDSDVAQHALAALKLLQGSHTTTANAIASHKIAAAAASSGTLEEEVSCDVVELRDQLNPAGEVHMLVTQRIRRQSPNSCYYVCEYCAKEFSKSYDLIRHRRAHTKETPYLCSKCLKRFATRSKLNEHLKRLHAAVKKHACSVCISSFSSKSQLHRHLGEQHADMVYSCRHCSRTFQTKSACDAHTKLETDPLRRNLLELLPQPVLSQRSFKCIYCKKQFERKFNCRTHMLLHLRRLMDTEQLRHSCLQCGKHFKRPNDLARHLLTHSKLKLHKCHVCQRCFTLKSTLARHLETHLPQRSSVNCQVCGRSYASKTSLQLHLRLHTGERPFKCERCGETFRTSGHRLEHMRAERHKNASSHALIL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00516414;
- 90% Identity
- -
- 80% Identity
- -