Basic Information

Insect: Drosophila leonis
Gene Symbol: -
Assembly: GCA_035045365.1
Location: JAWNPC010000819.1:1393382-1398039[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0013 0.099 13.3 1.4 1 23 221 243 221 243 0.97

2 26 0.048 3.6 8.4 2.0 1 23 249 271 249 271 0.97

3 26 0.27 20 6.1 0.1 2 20 303 321 302 321 0.94

4 26 0.00091 0.068 13.9 1.4 1 23 401 424 401 424 0.94

5 26 1.3 99 3.9 2.7 2 23 436 459 435 459 0.93

6 26 3 2.3e+02 2.8 0.5 1 19 465 483 465 485 0.91

7 26 2.9 2.2e+02 2.8 0.8 2 23 502 523 501 523 0.96

8 26 0.023 1.7 9.4 0.8 2 23 604 626 603 626 0.96

9 26 0.0015 0.11 13.1 0.1 1 22 635 656 635 656 0.96

10 26 0.71 53 4.8 5.2 1 23 665 688 665 688 0.95

11 26 0.0011 0.085 13.6 0.2 2 23 720 741 719 741 0.97

12 26 1.5e-05 0.0011 19.5 5.7 1 23 749 771 749 771 0.99

13 26 3.6 2.7e+02 2.5 1.1 1 23 919 942 919 942 0.87

14 26 1.6 1.2e+02 3.7 1.7 3 22 951 970 950 970 0.92

15 26 0.25 19 6.2 0.7 1 23 979 1002 979 1002 0.90

16 26 1.1e-05 0.00086 19.8 1.9 1 23 1027 1049 1027 1049 0.97

17 26 0.00015 0.011 16.3 0.9 1 23 1056 1078 1056 1078 0.98

18 26 0.028 2.1 9.2 0.0 2 21 1105 1124 1104 1125 0.94

19 26 0.058 4.4 8.2 3.9 1 23 1170 1193 1170 1193 0.96

20 26 0.0028 0.21 12.3 1.1 1 23 1230 1253 1230 1253 0.95

21 26 0.022 1.6 9.5 3.1 1 23 1281 1304 1281 1304 0.97

22 26 1.4e-05 0.0011 19.5 0.1 2 23 1332 1353 1331 1353 0.95

23 26 0.00065 0.049 14.3 2.5 1 23 1359 1381 1359 1381 0.99

24 26 2.4e-06 0.00018 22.0 2.0 1 23 1387 1409 1387 1409 0.97

25 26 6.1e-08 4.6e-06 27.0 2.4 1 23 1415 1437 1415 1437 0.99

26 26 0.00019 0.014 16.0 0.5 1 23 1443 1465 1443 1465 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0013	0.099	13.3	1.4	1	23	221	243	221	243	0.97
2	26	0.048	3.6	8.4	2.0	1	23	249	271	249	271	0.97
3	26	0.27	20	6.1	0.1	2	20	303	321	302	321	0.94
4	26	0.00091	0.068	13.9	1.4	1	23	401	424	401	424	0.94
5	26	1.3	99	3.9	2.7	2	23	436	459	435	459	0.93
6	26	3	2.3e+02	2.8	0.5	1	19	465	483	465	485	0.91
7	26	2.9	2.2e+02	2.8	0.8	2	23	502	523	501	523	0.96
8	26	0.023	1.7	9.4	0.8	2	23	604	626	603	626	0.96
9	26	0.0015	0.11	13.1	0.1	1	22	635	656	635	656	0.96
10	26	0.71	53	4.8	5.2	1	23	665	688	665	688	0.95
11	26	0.0011	0.085	13.6	0.2	2	23	720	741	719	741	0.97
12	26	1.5e-05	0.0011	19.5	5.7	1	23	749	771	749	771	0.99
13	26	3.6	2.7e+02	2.5	1.1	1	23	919	942	919	942	0.87
14	26	1.6	1.2e+02	3.7	1.7	3	22	951	970	950	970	0.92
15	26	0.25	19	6.2	0.7	1	23	979	1002	979	1002	0.90
16	26	1.1e-05	0.00086	19.8	1.9	1	23	1027	1049	1027	1049	0.97
17	26	0.00015	0.011	16.3	0.9	1	23	1056	1078	1056	1078	0.98
18	26	0.028	2.1	9.2	0.0	2	21	1105	1124	1104	1125	0.94
19	26	0.058	4.4	8.2	3.9	1	23	1170	1193	1170	1193	0.96
20	26	0.0028	0.21	12.3	1.1	1	23	1230	1253	1230	1253	0.95
21	26	0.022	1.6	9.5	3.1	1	23	1281	1304	1281	1304	0.97
22	26	1.4e-05	0.0011	19.5	0.1	2	23	1332	1353	1331	1353	0.95
23	26	0.00065	0.049	14.3	2.5	1	23	1359	1381	1359	1381	0.99
24	26	2.4e-06	0.00018	22.0	2.0	1	23	1387	1409	1387	1409	0.97
25	26	6.1e-08	4.6e-06	27.0	2.4	1	23	1415	1437	1415	1437	0.99
26	26	0.00019	0.014	16.0	0.5	1	23	1443	1465	1443	1465	0.97

Sequence Information

Coding Sequence: ATGTTGCCGACAGATATTTGCCGTACATGCGCGCTGCATGATGATAGCTTGCTTCCGCTTGCGGCCCCCAGtgataaatatacaaataaaagtttaaatgACATGTTACTCGAATTGACACAAAATGATCCCCTGCAAGAGCACACGGATGATAGTCTGCCGCAGCACTTGTGCATTGGTTGCTTGCACAAGTTGGAGGCTGCGTATGCGTTCGTGTTGCAGGCGCGCCAGGCTCAagagcaattgttgttgcagctgcgcaAAGGCTTACATACACAGTGCTTGGATGAGATGCCCATCGACATTAACTTGCAGCACATCAAAACCGAAACGATCGTTGACATGCAACTAACTAGCAAAACCAAGAGTGAAGAAGATGAGGCAGATGCCGAAGAGAGGGACCAAGAAATGGCTGCAGTGACTATTCCAGCCCTGAAGTGGCGGCTAGAAAGCGATAGTGACAGCAATCAGACTGCAGTTGATGACCAGGACGTAGACTTTAAGCCCAAGCAGTTGCGGCGCAGTGCACGTAAAGCCAAACCCGGCACAGACAACGAAAATGAAGCAACCTCTGTCCATGCGAATCCCTTGCCTATTAAACGGCGACGTGGTCGCCCAGCACGTCTGCCCAAAAAGGAAACGAAAAACGAAGAAGGACGGCATGTGTGCGAGGTTTGTGGAAAGACCTTTTCGTGGTACCGCGACATGCAACGCCACTCGCGCATACACTTCGAGCAAGCGACATTCGTGTGTGACAGTTGTGGCAAGAGCTTCTTGCGCAAGGACAAGTACATGTTTCATCTGCGTTCACACGAAAGGCGTGCAGTCAAGTGTCAGGCCATACAACTGAGCAGCGAATGGCGCTTCGCTGAACGCCTCTATAGCTCCGGACGGCTCAAACGTGTCGAGTGCAAGCTGTGCGGCTTGAAATACCAGCGCATAAGGGAGCTGCGCGAGCATCTGCCGTGCCATACAAGCATTGAGACTCTGTCCAAACTGAGTCTAGAGAGTGATGTTATCAGGGAACAGTTTgccaaagagcagcagcagttagaCTTGGCGCTGATCAAGCAACAGTTGTGCGCAGACATCGCCAAAGGATGTGGTCAGCTGGACAAGTACTGCGCTGTGGTCAACGCTTACGGTTATGAGCTCTGCCTTAGCGACTCAGACGAAGAGGTAGCTGACAGGTCGCCTGAATACCAGTGCCTGTCGTGCAGCATTAACTTCAGGCGCAAATATAGCCTTATGCGGCACACCCTGGAAGAGCACACACAGACGGACACATCAGTGTCTTGCACACAACGCTGTGATGTTTGCcaaattggttttgtgtgtgcTAATATGTTGGAGCAACATCAACGCACGCAGTGCCACAATAAACTGAAGCGTTACAACTGCCCTACCTGCCCAGGTAAATTTATTTGGCTGCAGAACCTGAAGCAGCATGCGTGCCCGCAACGTACGAAGCAGCACGacgagcagcggcagcggcagcaaaaaCAGTGTTGTCTCTGTGATATCCAATTGAACAAGATGCTCGAATTACGTGCTCATTTGCTTATCCATCAAGATGGCCGCAGTGGCGTATATCCCGAGCAGCAGGCAACCTTCTTTCGCACATACTATCCGAATGGCCTTGACTGCAGCTTGTCTGAGCTGAGCGCACGTATTGCCGCCGACTTTAAGGCGGAGGATTATGGGCGATACTTTAATGCCGGAACGAGGAATGGCGAGGAGCTCGATTTCTTTGCCTCGGACTCTGATTTAAGTGATGCGGACCAGCGGAGCTCTGGCGGTACGCTACAGAGATGTTCCCTGTGTGGCGAGACGAAATCGCGCCTGAGTCAATTGCTCGAGCATCAGCAAAGCCAGCATAGTGAGGCGCAGGAAAGGCTGCCATATGTCTGTGACGATTGCGATTTGAGTTTTGTAGCGGATTCGCTGCTCCAACAGCATCGCCGGCGCGTCTGTGGCAAGCAGCATGCCAAGTACTATTGCCAGCATTGCAGTCAGCGCTTTTACTGGCTTTCCAATTACGAGCTGCATATGCATCTGCAACACGAGACTCAAGCCGAGCTGCAGACGGATGTTGTCGATGAGCAGGAGCGGGGGTCAAGGCTGAGGCGCAAGCGCCAGTCTACAGCTGCCAAGTTGCAGTGCGGCGAGTGCGAAAAGGTGTTCATCTGGCCCAAGGATCTGACGCGTCACAAGCGCCTACACCAGCCACAGGCTTTGGCACAATACCAATGCTTGCACTGTGATCGCAAGTTCCATCGCAAAGATGGGCTCAAGTCGCATATGCGCGTGCATGGCGAACAGCAGGTGGATGCAGCGATTGCCAGTGAACAAGTTCCATCCATGGTGCAGCGCATGCCCGTGGTGCTGACCCAACTGTGTCGACCTAATGGTTGCAAGCAAATTCAATGCATGATATGTCTCTCGCAGCATACCAAGATATCTGATCTGCGCACACATTTGGTTAATCATCAGTATTCTGTCAAATTTGCGGAGGAGCGAGTCCAGGCGGAAAGCATTGCGGGCATTTCACGTTCTCTGTATCCAGAACTAGCCACACCAttggagcaacagcaattaaTCGAACGCATTCAAAAGGATGTGACAACAGGCGTGGAGCTGGACAGATTCATATCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGACAGCAGCGAAACGGAAACCGATTCCGACTCTGCCGAGGCAATCAGAAGCAAAAGCGTACAACTCTATAGTTGTGAGCTATGCCAGCTGAAGGTATTACGCAAGCATCAGCTCTACGCCCATGAGCTGGAGCAGCATTCGTGGCAACAGGCAACCCGTGTTTGTAACTGCTGCCAGGCGAGATTCGTTAATGAGCAGCTACTAGAGCATCACACTCGGACGCTCTGTCGCAACGTGCAGCGACGATTCTTTTGTCGTAAATGTCCGCTACGTTTCCGCTGGCGCGAGAACCTGAAGTTGCACTCGGACGTGGCGCACAACGAAGCCAGAGGCGAGCATTCGAGCATAGGCATTAAATTGAACGGGACGCCTCTGTTGCCCAGCGTTAGTTACGACTGCACCGAATGCAATCGTagctttaaaatgcaaaaggaTCTTACCAGACACACTCTGATGCATGCCCAGGAGTCAAGCATTTATCGTTGTCGCTGGTGTGCACGACGTTTCTACCGCCAGGCCAATCTACTGCAGCACATTGAGCGCCATGGCATTAGCGCTGAACAGCTGCCCTATGCTGAGGCCCTGCTCAATGCCAGCCGTCATCCGAATGGTCCGAAGTGTATTCAGTGCAAGGTGTGCAACGTGACCTACCCCACCATTGCTGCGCTGCGCAGCCATCTTCAATCAGCGCCAGCAGGCACACATCATGAGTTTGGCTCGTTACTCAACTACTCCATTACCAATCAGTTGGGGTACGAGTTGCATCTGGAGGACTCGGAAACGGATGAGGAGGCTAAGCCAACAGGTACGCCCACGCACTACACCTGCGGCCTATGCCAACTGCGCTGTGTGCGCAAGTTTGAGCtgcatcaacatcagcaagcGATGCATCGACTGGAACGTATCAACGAGGGCTGTGATGTCTGTATCTTTAAGAGTGTCTCAGCAGATCTCATTGCCTATCATCGACGCGTCTTGTGCAATAATACGGAGAAACACTTCAAATGCTCCAAGTGTGGCTACAAGTTTATGTGGGAAACGAATTTGTTGCGGCATATGGAGTTGCAGCATCCAAGCAGCGAAAGGAGCGAAGCGCAGAAGGATGCCAGTGCTTTGTCTGCACAGGATGTATCTAAGGTTGAGTGCCAGATTTTTCAGTGCGCCCAGTGCCCTAGTAAATATAATCGCAAGGATCGTCTCACAGCACATGTAAAGAAGTGTCATGTAGCGGGCGCAAGTGGCCCCACGGCTGCGGCAGCGCAGCTTATGAAAAATTCAACTGGCGCCAAGCAGCAGAAAAGTTTTCTTTGCGCTTTCTGCGGCAAGGCGGTTAGCTCCTCCTCAAATCTGATTATACACATACGTCGCCATACTGGCGAGAAGCCTTTTAAGTGTGACTACTGCGCCATGGCTTTTCCACGCTCCTCCGATCTGCAGTGCCATCGACGCACCCACACTGGCGAGCGGCCGCACGTCTGCACCGTTTGCCAAAAGGGCTTTGCTCGATCCTACAAGCTGCAGCAACACATGCGCATCCACAATGGCGAACGCCCATATAAGTGTACATATTGTGACAAGAGTTTTACGCAGTCCAATGATCTGACGCTTCACATACGACGGCACACAGGCGAGCGGCCCTATCAGTGCAATACGTGCGGCGAACGTTTTATTCAGGGCACAGCCCTGAAGAATCATCGCCTGCAACATGGACACCACGATACGGAAGTAGACCAGGTCAAAGATAACTAA
Protein Sequence: MLPTDICRTCALHDDSLLPLAAPSDKYTNKSLNDMLLELTQNDPLQEHTDDSLPQHLCIGCLHKLEAAYAFVLQARQAQEQLLLQLRKGLHTQCLDEMPIDINLQHIKTETIVDMQLTSKTKSEEDEADAEERDQEMAAVTIPALKWRLESDSDSNQTAVDDQDVDFKPKQLRRSARKAKPGTDNENEATSVHANPLPIKRRRGRPARLPKKETKNEEGRHVCEVCGKTFSWYRDMQRHSRIHFEQATFVCDSCGKSFLRKDKYMFHLRSHERRAVKCQAIQLSSEWRFAERLYSSGRLKRVECKLCGLKYQRIRELREHLPCHTSIETLSKLSLESDVIREQFAKEQQQLDLALIKQQLCADIAKGCGQLDKYCAVVNAYGYELCLSDSDEEVADRSPEYQCLSCSINFRRKYSLMRHTLEEHTQTDTSVSCTQRCDVCQIGFVCANMLEQHQRTQCHNKLKRYNCPTCPGKFIWLQNLKQHACPQRTKQHDEQRQRQQKQCCLCDIQLNKMLELRAHLLIHQDGRSGVYPEQQATFFRTYYPNGLDCSLSELSARIAADFKAEDYGRYFNAGTRNGEELDFFASDSDLSDADQRSSGGTLQRCSLCGETKSRLSQLLEHQQSQHSEAQERLPYVCDDCDLSFVADSLLQQHRRRVCGKQHAKYYCQHCSQRFYWLSNYELHMHLQHETQAELQTDVVDEQERGSRLRRKRQSTAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYQCLHCDRKFHRKDGLKSHMRVHGEQQVDAAIASEQVPSMVQRMPVVLTQLCRPNGCKQIQCMICLSQHTKISDLRTHLVNHQYSVKFAEERVQAESIAGISRSLYPELATPLEQQQLIERIQKDVTTGVELDRFISITNEAGIELSLDSSETETDSDSAEAIRSKSVQLYSCELCQLKVLRKHQLYAHELEQHSWQQATRVCNCCQARFVNEQLLEHHTRTLCRNVQRRFFCRKCPLRFRWRENLKLHSDVAHNEARGEHSSIGIKLNGTPLLPSVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPNGPKCIQCKVCNVTYPTIAALRSHLQSAPAGTHHEFGSLLNYSITNQLGYELHLEDSETDEEAKPTGTPTHYTCGLCQLRCVRKFELHQHQQAMHRLERINEGCDVCIFKSVSADLIAYHRRVLCNNTEKHFKCSKCGYKFMWETNLLRHMELQHPSSERSEAQKDASALSAQDVSKVECQIFQCAQCPSKYNRKDRLTAHVKKCHVAGASGPTAAAAQLMKNSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHHDTEVDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509945;
90% Identity: iTF_00476759;
80% Identity: -