Dlat015488.1
Basic Information
- Insect
- Drosophila lacteicornis
- Gene Symbol
- HINFP
- Assembly
- GCA_008044355.1
- Location
- VNKF01001520.1:70146-72818[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0046 0.37 11.4 0.1 1 23 125 149 125 149 0.97 2 8 0.45 37 5.1 1.8 2 23 168 191 167 191 0.95 3 8 0.00099 0.081 13.5 1.3 3 22 199 218 198 218 0.95 4 8 4e-05 0.0033 17.9 1.8 1 23 227 249 227 249 0.96 5 8 5.2e-06 0.00043 20.7 4.1 1 23 253 276 253 276 0.98 6 8 7.9e-05 0.0064 16.9 0.6 2 23 283 305 282 305 0.96 7 8 0.14 12 6.7 1.5 2 23 311 335 310 335 0.89 8 8 0.32 26 5.6 4.7 1 23 342 365 342 365 0.95
Sequence Information
- Coding Sequence
- atgAACTTTCGCTCAAAGGAGTCGCAGCACATCGAACAGTTGCCAGTGAACCATGTCGCAGCCATTGTCGCTGTCTCTGGCGGCTGCCAGGATATCTGCTGCGGGGAGTGGAACCTGAACAGCCACATTGGTCAGCACCTGGAGCAGTATGCCCGCGAGCAGGCGGCAGAGGCGGAGGAGCACGTGTGCTGCTGGATCGAGTGCGATTTCCGTTGCAGCTGCCTGAAGGAGTTTAAACGGCACTCTTACTACCACGGCTACTATCTGCACCTACTGCTCCAGGGTCGGCTGGAGTGTGAATTGCATCCGGAGATTCCCGCCTGCACGGCGCCCTCCCGCCGCACCAAGAAGCTGCCTCATCTCGGCCAAAACTTCAAGTGCGGCTGGACTGACTGCGAGCGCGAGTTCGTCTCGATTGTAGAGTTCCAGGACCACATTGCAAAGCACGCCCTCTTCGAGTACGACATCCAGAAGACGCCCGACGACGAGCGGCCCAAGACGCAGTGCAACTGGAGCTTGTGCCACAAGCAGATGGGCAACAAATACCGCCTCATGGAGCACATCAGCACGCACTCGAACAAGAAGCAGGTGGCCTGCTTCCACTGCGGCGAGCTCTTCCGCACCAAGACCACGCTCTTCGATCACCTTCGCCGTCAGCCGGAGAACAACACGAACAGCTTCCAGTGCGAGGAGTGCTTCAAGTTCTTCGCCACCAAGAAGCTGCTGAAGAACCATGCGGTCCGGCACGTCAACTGCTACAAGTGCACCATGTGCGACATGACCTGCAGCTCGTCCAGCTCGCTGACCACGCACATTCGATACCGCCACCTCAAGGACAAGCCGCTGAAGTGCAGCGAATGTGAGACACGCTGCGTCCGCGAGTCCGACCTGGCCAAGCACATCCAGATTGTTCACTCGAAGAAGGTGCTCCGGTGCAAGCACCCGGACTGCCAGTATTCCGTACGCACCTACATGCAGATGCGAAGGCACTTCCTGGAGGTTCATGGCAATAACCCCATCCTGTATGCCTGCCACTGCTGCGAGCGCTTCTTCAAGAGCGGCAAATCCCTCTCCGCTCACCTGATCAAGAAGCACGGCTTCCGGCTGCCCTCGGGCCACACGCGGTTCACCTACCGGGTAGACGAGAACGGCCTGTATCGCCTGGAGACGACGCGTATCGAGAGCCTGGAGGTGACGCAGCAAATACTGTCGCCCCAGGTTAATCCAGCCCTGGAAAACGGCCTCAAGCCCGGCACTGGATCCTGCTTCGAAATAGTGGACTCCACAAACTCGGAATTCGAGCGGATCATCGTCTCCAATGATACCAATGAGGCGCAGCTAATGGGAGAGGTGATCATATCGCTGCCCAGCCTGAACGAGGACCTGTGA
- Protein Sequence
- MNFRSKESQHIEQLPVNHVAAIVAVSGGCQDICCGEWNLNSHIGQHLEQYAREQAAEAEEHVCCWIECDFRCSCLKEFKRHSYYHGYYLHLLLQGRLECELHPEIPACTAPSRRTKKLPHLGQNFKCGWTDCEREFVSIVEFQDHIAKHALFEYDIQKTPDDERPKTQCNWSLCHKQMGNKYRLMEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCEECFKFFATKKLLKNHAVRHVNCYKCTMCDMTCSSSSSLTTHIRYRHLKDKPLKCSECETRCVRESDLAKHIQIVHSKKVLRCKHPDCQYSVRTYMQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAHLIKKHGFRLPSGHTRFTYRVDENGLYRLETTRIESLEVTQQILSPQVNPALENGLKPGTGSCFEIVDSTNSEFERIIVSNDTNEAQLMGEVIISLPSLNEDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00606635;
- 90% Identity
- -
- 80% Identity
- -