Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: -
Assembly: GCA_008044355.1
Location: VNKF01008632.1:2969-5209[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.8 1.5e+02 3.2 0.1 3 23 292 313 290 313 0.87

2 9 2.1 1.7e+02 3.0 2.5 1 23 345 368 345 368 0.95

3 9 0.0014 0.12 13.0 0.9 1 23 376 398 376 398 0.97

4 9 9.5e-07 7.8e-05 23.0 0.6 2 23 406 428 406 428 0.96

5 9 0.00014 0.011 16.2 0.7 3 23 437 458 435 458 0.93

6 9 0.012 0.95 10.1 0.3 2 23 467 488 466 488 0.97

7 9 0.081 6.6 7.5 1.4 1 23 497 519 497 520 0.95

8 9 1.9e-05 0.0016 18.9 0.5 1 23 525 547 525 547 0.98

9 9 0.0084 0.69 10.6 8.3 1 23 553 576 553 576 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.8	1.5e+02	3.2	0.1	3	23	292	313	290	313	0.87
2	9	2.1	1.7e+02	3.0	2.5	1	23	345	368	345	368	0.95
3	9	0.0014	0.12	13.0	0.9	1	23	376	398	376	398	0.97
4	9	9.5e-07	7.8e-05	23.0	0.6	2	23	406	428	406	428	0.96
5	9	0.00014	0.011	16.2	0.7	3	23	437	458	435	458	0.93
6	9	0.012	0.95	10.1	0.3	2	23	467	488	466	488	0.97
7	9	0.081	6.6	7.5	1.4	1	23	497	519	497	520	0.95
8	9	1.9e-05	0.0016	18.9	0.5	1	23	525	547	525	547	0.98
9	9	0.0084	0.69	10.6	8.3	1	23	553	576	553	576	0.98

Sequence Information

Coding Sequence: ATGATATGCCGACTCTGTCTGGAGGATGCTGAGCACGGTGTGCCCATTTTCGGGCAGGAGACGGCGGCCGTGCAACCGGCGCTGCTGATCGAGCGTCATCTGCAGCTGGTGTTGGCGGCCAACGATGCGGTGTCCACGAGTCTGTGCAACCGATGCTGGCAACAGCTGGGCGACATCGAGCTCTTCTGCGCCATGGTGGCGGACAAGCAGCGCTCCCTGCACCGCTCCTTGCAGCTCAAGACGGAAATGCCCGAGCTGCCGGAGCTGGCTGACCCAGAGCCGGAGCCCGCCATGGTTGTGTGGAATACGGAGACGCCCATGGAGCCGAAGATAGGTTTCGATGGCGATGACATCAAGGATCATATACTTTGCGAACCGGTCATCGATGCAATGTCCGCCGGCGACGACAAGGACAGCGACTACGGCGACACCTTTGAGCCCGGTTACCAGTCCGAGGGGGAGATGGAGCCCAAGGCGGATCCGGTGAAGCCACGGCGCAGGGGCAGGCCGCGCAAGACGCCGCTGCAGCAGACGCAGCAGATCATCAAGCGGAAGTACGAGAAGCGGAAGCAGCCAAAGCCAGCCGAGCTGTCGCTGCGCGAATCCCGAGCGCGTTTAAGGGAGCTAAAGCGCAGCAGCACAGGGGGAGGGGGagatgatgacgacgaggaggacgaagatgaggacgaggaggaggaggagaaggaaggCATGCCGGCGGCAAAGGCCAAGCCCAGTGCGGGCAAGCGCGGTCGGCCAAAGATCAAGAAGGAACCgggcggcgacgacgacacGGATCCCACGGACGCGCCCGTCAAGCGCAGCAGCATCAAGGAGATGGACGACTATATAGCCGCCAATGTGAAGCTGGACTGCGCTCTGTGCGCTGCACCGCTGGAGGACTTTAACGATCTCAAGCGCCACTTCCGCGTGGAGCACGATTGCACCGGGTTTGTCAAGTGCTGCAACAATCGATACAAGAAGCGGACACTGTACGTGGATCACCTGCACTGCCACAAGGATCCGCAGTACTTTAGCTGCCAGAGTTGCCGCAAGAATTTCCTCAATCGCAACAGCCAGGTGATGCACATGCTGCGCTTCCAttcccagcagcaggagctggtcCATCAGTGCGCCATCTGTGAGGCGCGCTTCGCCAAGAAGTTCCTGCTGACCATGCATCTCAAGGGGCACAAGGGCACGGAGCGGCCGGAGGTGTGCGAGGACTGCGGCAAGACATTCCGCACCAAATTCGAGCTGAGCGCCCATGTCAAGCGTATGCATGCCGCTGACTTTACGCCCATCATTTGCGACATTTGTGGAACGCATTTCCGTTCCAAGGCCAACTTCCTGATACACAAGAAGGCTCTGCATCCGGACGGGCCCGTGGCGGAGGTGCAGTGTACCCTGTGCGGCCGCTGGCTGCGGGACGAGCGGAGCCTGCGCAAGCATCTGGCACGCCACGATGATCGCGACGGCGACACTAAGTACCGATGCCTGCTCTGCAACGCAGAGAAGTCATCCCGTGCCGCACTCAGCAGCCACATGCGGTACCACCACTCCGCCAAGCGGCACAAGTGCAGTCTCTGCGACAAGGAGTTTAAGCTGCCGCGCGCTTTGGCCGAGCACATGGCCACCCACACGGGCATCGATCTGTACCAGTGTCAGTTCTGCACGCGCACCTTCAAGTCCCATGCCAATATGCACAACCACAAGAAGAAGATGCATCCGAACGAGTGGGTGCGCAAGTACTcgcagcccagcagcagcatcaatgCCACCAATGCCGCCACATCCTCCAGCCTGGCCACTCTGACTCCTCTGCCTCCTCCAcaagcccagcagcagcagcagcagcaacagcagcagcctccacCGCCAGCACCACAGATGCTGCCTGGGATGGGTGCACCTCTGACCATTGTCCCAAAGTCCCTCATCGAGATACCCGACCCGGAGGGCTTTGACTTTGCCAGCAACAGCTCCGTGTGCCCCACACCCGACTGA
Protein Sequence: MICRLCLEDAEHGVPIFGQETAAVQPALLIERHLQLVLAANDAVSTSLCNRCWQQLGDIELFCAMVADKQRSLHRSLQLKTEMPELPELADPEPEPAMVVWNTETPMEPKIGFDGDDIKDHILCEPVIDAMSAGDDKDSDYGDTFEPGYQSEGEMEPKADPVKPRRRGRPRKTPLQQTQQIIKRKYEKRKQPKPAELSLRESRARLRELKRSSTGGGGDDDDEEDEDEDEEEEEKEGMPAAKAKPSAGKRGRPKIKKEPGGDDDTDPTDAPVKRSSIKEMDDYIAANVKLDCALCAAPLEDFNDLKRHFRVEHDCTGFVKCCNNRYKKRTLYVDHLHCHKDPQYFSCQSCRKNFLNRNSQVMHMLRFHSQQQELVHQCAICEARFAKKFLLTMHLKGHKGTERPEVCEDCGKTFRTKFELSAHVKRMHAADFTPIICDICGTHFRSKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKSSRAALSSHMRYHHSAKRHKCSLCDKEFKLPRALAEHMATHTGIDLYQCQFCTRTFKSHANMHNHKKKMHPNEWVRKYSQPSSSINATNAATSSSLATLTPLPPPQAQQQQQQQQQQPPPPAPQMLPGMGAPLTIVPKSLIEIPDPEGFDFASNSSVCPTPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490331;
90% Identity: iTF_00606591;
80% Identity: -