Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: -
Assembly: GCA_008044355.1
Location: VNKF01012718.1:124717-127167[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.2 5e+02 1.5 0.3 6 23 276 293 276 293 0.89

2 8 0.0002 0.017 15.7 0.7 1 23 299 321 299 321 0.99

3 8 0.034 2.8 8.6 5.8 1 23 330 352 330 352 0.95

4 8 0.00019 0.015 15.8 0.6 2 23 361 383 360 383 0.95

5 8 0.00046 0.037 14.5 0.0 3 23 391 411 390 411 0.96

6 8 0.00082 0.067 13.7 1.2 2 23 420 442 419 442 0.96

7 8 1.9e-07 1.5e-05 25.2 1.3 1 23 479 501 479 501 0.98

8 8 1.1e-05 0.00094 19.6 3.2 1 23 507 530 507 530 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.2	5e+02	1.5	0.3	6	23	276	293	276	293	0.89
2	8	0.0002	0.017	15.7	0.7	1	23	299	321	299	321	0.99
3	8	0.034	2.8	8.6	5.8	1	23	330	352	330	352	0.95
4	8	0.00019	0.015	15.8	0.6	2	23	361	383	360	383	0.95
5	8	0.00046	0.037	14.5	0.0	3	23	391	411	390	411	0.96
6	8	0.00082	0.067	13.7	1.2	2	23	420	442	419	442	0.96
7	8	1.9e-07	1.5e-05	25.2	1.3	1	23	479	501	479	501	0.98
8	8	1.1e-05	0.00094	19.6	3.2	1	23	507	530	507	530	0.98

Sequence Information

Coding Sequence: ATGCCGTGTTTTTTGTGCACGGAGCATGCGGACAACGTCGTGGGCAACATCCAGTTCGCCTCTGAGAGGGCCGACACCGTGGGCCTGCGACGCATCATCGAGCAACACTTTTGGCTTCGGGTACATGACTCAAGCAGCGGCTACGTATGCGGCGGTTGcttggagcagctgctgctcttccACAGCTTCTACAGCATGGTGGAGCAGGCCCACAAGGCGCTGGAGGAGACGACACATGTGACGGTGGCTTCTCTGCCCACAGAAGTGCTTTCTACAATTCTTGGAGGAGGCGAAGGTGTGGTAAAGAGTGAGGAAGTAGAGAGCGTGGCGGCTGCCGTGAAGCGCCGGCGAGGACGTCCCCGCAAAACGGAGGTAAAGGATGCCAGCGAGGAGCTCAAGAGCGTGCTGGAACAGATCAACTTGAACGAGATCAAAATTGAGTACCCCGAGGCGGACCTGACCATAGCCGATGTTCTGGAAGACCAGGAGGAGCACGAGTACATGCCAAGCGGCTGCGAAAGCGAGGGTGATGGTGAGGATGATGAATTATTGGCAGAGATACCGCCGCCCAAGGTCCAGCGCAAAGTTCGCGGTCGTCCCAGAACgcgtggccgtggccgtgggCGTGGAAAGGTGCGCCTGCCTGAGCGGCCTAAGCCAAAGAGAACTGGTGTGCCGAACATGACAAAGTCGAAGGAGTTCAACGATTACATTCGGGAGCACTACAAGGTCCATTGCCCCGTCTGCAGCTCGCCCATGGAGGGATTCTCGGAGATGCTGGTGCATGTGCGGCGCGAGCACAAGCAGCGTGGCTACTCGACGTGTTGCAACCGCAAGTTCTGGAAGCGCGGCGTCCTCGTCGACCACCTGCGCCGCCACCAGGACCCGGAACTCTTCAAGTGCACCATCTGCTCGCGCGTGATGGGCCAGCGCCGGAGTCTGGAGCTGCACATGCGCATGCACGAGATCAAGGCGAACGGACGCCTCTACCAGTGCGAGCACTGCTCCAAGAGCTTCTACAGCTCGGTGGTGTGTGAGCGCCACAAACTGACGCACATTCCCCGGGATCAGTGGCAGATCAAGTGCACAAACTGCGAGAAGACTTTCCCCACTGAGTACCTGATGAAGCAGCATGTGAAGCTGGTCCACCTGAatttatatgccaagatctgTGACGTCTGCGGCAAGTCCATCCGCGGCAGGGAGGCCTTGGCCCGCCATATGGAGGAGCACACGGGCGCCCCACAGGCAGCCATTAGCTGTCATCTTTGTGACTCGAAGCTGACCACCAAGTATGGACTGGCTAGGCACATAAAGATGATGCACACCGCCGAGAATCTGCAGCCGATGCAGTGCGAGCACTGCCTGAAGATCTCTCCCAGCCTGCAGGCGCATCAGCACCACCTGAAGTACACCCACAACACGGCTCGCACGCACCAGTGTCCCATGTGCGAGAAGGCCTTCAAGCGGCCCAACGAGTTAAAGGAGCACATGACCACTCATACCGGGGAGGTGCTGTACACCTGTCCCCACTGTCCCCAGACCTTCAATTCGAACGCCAACATGCATGCCCACCGGAAGAAGGTGCATCGCAAGGAGTGGGAGGAGAACCGCCACAAGCGCCAATACTCCGCACGGAAATCGGACACGATCATTGCCGTAAGCGTGCGCAAGACGACGGAGGCCCGGCTCGATGGAGGCGCAGGAACGGCGGCAGCCGTAAGCTCGGGAGCCGAATGCTAG
Protein Sequence: MPCFLCTEHADNVVGNIQFASERADTVGLRRIIEQHFWLRVHDSSSGYVCGGCLEQLLLFHSFYSMVEQAHKALEETTHVTVASLPTEVLSTILGGGEGVVKSEEVESVAAAVKRRRGRPRKTEVKDASEELKSVLEQINLNEIKIEYPEADLTIADVLEDQEEHEYMPSGCESEGDGEDDELLAEIPPPKVQRKVRGRPRTRGRGRGRGKVRLPERPKPKRTGVPNMTKSKEFNDYIREHYKVHCPVCSSPMEGFSEMLVHVRREHKQRGYSTCCNRKFWKRGVLVDHLRRHQDPELFKCTICSRVMGQRRSLELHMRMHEIKANGRLYQCEHCSKSFYSSVVCERHKLTHIPRDQWQIKCTNCEKTFPTEYLMKQHVKLVHLNLYAKICDVCGKSIRGREALARHMEEHTGAPQAAISCHLCDSKLTTKYGLARHIKMMHTAENLQPMQCEHCLKISPSLQAHQHHLKYTHNTARTHQCPMCEKAFKRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEENRHKRQYSARKSDTIIAVSVRKTTEARLDGGAGTAAAVSSGAEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00541314;
90% Identity: iTF_00609393;
80% Identity: -