Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: -
Assembly: GCA_008044355.1
Location: VNKF01013945.1:125795-128715[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0031 0.26 11.9 0.6 1 23 510 532 510 532 0.99

2 7 0.0058 0.47 11.1 1.9 1 23 540 562 540 562 0.97

3 7 0.00084 0.069 13.7 0.7 1 23 571 593 571 593 0.98

4 7 3.7e-05 0.0031 18.0 0.2 3 23 668 688 666 688 0.97

5 7 0.00064 0.052 14.1 1.0 1 23 696 720 696 720 0.98

6 7 2.1e-07 1.7e-05 25.1 2.2 1 23 726 748 726 748 0.98

7 7 0.00021 0.017 15.6 0.1 1 23 754 776 754 776 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0031	0.26	11.9	0.6	1	23	510	532	510	532	0.99
2	7	0.0058	0.47	11.1	1.9	1	23	540	562	540	562	0.97
3	7	0.00084	0.069	13.7	0.7	1	23	571	593	571	593	0.98
4	7	3.7e-05	0.0031	18.0	0.2	3	23	668	688	666	688	0.97
5	7	0.00064	0.052	14.1	1.0	1	23	696	720	696	720	0.98
6	7	2.1e-07	1.7e-05	25.1	2.2	1	23	726	748	726	748	0.98
7	7	0.00021	0.017	15.6	0.1	1	23	754	776	754	776	0.98

Sequence Information

Coding Sequence: ATGAGTGTGCTGGCGTATCCACGTACCAACGATGAGGAGATTTTCCGACACTGCGGCAAGGACTGCGGGGTGGTGACGGCCACCGAGGACTTCCAGTACTTTGCGCTGCGCTGCATCTTCTGCAGCGAGAAGTTCCTCTACTTTGACTCCTTCATTGGCCACATGCAGACGGCGCATCTGGGCGACCAGTCGGTGGCGAATACCACAGAAGCTGCCGCCGGCGCCGCTACCTCCACCTCAACGGGCGCTGGCGGCGACGGCACCACCTCCAATTCAGCCAGCACTCTCCTGGGCCTGCGTCTCGGCGAGCCCATGTCCCTGTCGGAGGCGGGAATGCATCGCGACAATGGTGAGCACCTGCTGCCCAACTTCCATGAGATCGAAGACTTGACGGACGCTGATACGGCGCTGCTGGAGCCGCAGATGGTCATCAAACAGGAGCTGCAGGATTTGCCCTGCAGCGAcgccgacgaggaggaggaggagaacgaTGACATGACCGATTCCAATGCTGAtcccgacgaggacgaggccaTTCTGCCCGAAAGCGATGTCCCGGCGgtgagcggcagcagcagcaatcggCCCAGGCCGCGCATGAAGGTGACAAAGCCCCGCCAAACGGATATGTCGAACGAGACGCCACTTgacggcgatggcgatggcggcgACGACTCCTTCACGGACGAGTACGGCGCGGACCTGGACAACTACATGGACGACAACTCGGCGGAGTACATGGACTACGGGGAGCCCTTCGAGCCCAGCCAGCTGTGCATGGACTCTGACTTTCTCAGCTACGACGATCTCGTGGAGGAGTCCCTGCTGGGGCGCGTGGGCGAGGTGACGATGCACATCAAGGACCGCAAGATGATCAAGTTCCTCATCCAGTCGTACAAGCGCAACCCCTTCCTCTGGGACCATGGCAATCCGCAGTTCCGGGATCGGGTGAAGCGCGCCCGCTTCCTCGACTGGATCGTGCTGGAGTTCAAGAGCCGCTTCAACATCTCGCTGGCCAAGGATGCCATTACGCGGAAGTGGGACAACCTGCGGACGGTGTACAAGCGCGAGTGCAATCGCATGGCCCTCGAGAAGACCAACATCAGCACGCTGTGGTACTTCAAGGAGCTGCACTTCCTCAACGAGGTCTACAGCTACAACGACAAGATGTCCGATGCCGTGGTGAAGGAAACCTCGTATCGTCGCCGCTTCTCGGCCATTTGGAACGACACCTCGACGGCCAAGCTGCTGAGCATGGTGAAGCGGTATCAGTGCTTCTACAACCGCTTCGATCCCGACTACCGCAGCAAGGAGCGGCGTGGAGAGGGCCTCCACCAGATGGCcatggagctgcagcagctgatcGATGTGACCACCATCCAGATATCGAAGCGAATCTCCCAGCTGCGCTTCGACTACTCCAAGCAGAAGATGGAGCGCCTCAATTGCGAGCGCCTCGGCCGCAAATTCATTGCCAACTACATCTACTACGACCAGATGCACTTTATGGACGAGGACATACCGCCCTTCAAGTGCCAGCACTGTCCGGAGATTGTGCAGACGCTCCGGGAACTGGATCTCCACATGCTCACCCATCAGCCCAGTCTGGGTGGTGGTTACTACTGCAATATCTGCACCATTCAGTTCCACACGGCCGAGGAGTTCGAGAGCCACAAGCAGCTGCATTTGGGCGCCGGCAACGAGGTCAAGTTCAACTGCGAACTGTGCACGGCCAGCTTCCGGGAGAAGGCCAACTACGATGAGCATCTGCGGCGGCACAACGAGGAGCTCTTCCTGCCCTCGCTGGCCATGAATCATAGCATTCTGGAGGCCTGTGCAGCGGACGAGGCGAAGGTGGAGCCTCCCAGCGGCAGAGGGCGAAAGAGGAGCTCCCTGGCGAAATCATTACCTGCAGCGGTCATCAAggatgacgaggaggagacGACAacgacggcagcagcagcgggcggcaCCGGCAGCGATGTGGCCAAACCGTACGGCTGCGAGGTGTGCCGGAGGAGCTTCGCCACACCGGGCCACCTCAATGCCCATCGGATTGTGCACCAGGACGAGCGCGAGCGGTGCTACAAGTGCGACTATCCGCAGTGCAATAAATCGTTTGTGGCCCGGAACAGCCTGTTCGAGCACCTGAAGCAGCACTACAGCAACGAGGAGTTCAAGTGCGACATCTGCGGCAAGACGTTCAAGTCGACGAAGAACCTGCAGAACCACAAGCAGATTCACGACAAGGTCAAGCGCTACGTCTGCCAGATCTGCGGCTCGGCCTTTGCCCAGGCGGCCGGCCTCTATCTCCACAAGCGGCGGCACAATCGTCCCAATGGCGCTGTGGGCGCCGTAGGACGCTCCGGCCGTACCACCCTGTGA
Protein Sequence: MSVLAYPRTNDEEIFRHCGKDCGVVTATEDFQYFALRCIFCSEKFLYFDSFIGHMQTAHLGDQSVANTTEAAAGAATSTSTGAGGDGTTSNSASTLLGLRLGEPMSLSEAGMHRDNGEHLLPNFHEIEDLTDADTALLEPQMVIKQELQDLPCSDADEEEEENDDMTDSNADPDEDEAILPESDVPAVSGSSSNRPRPRMKVTKPRQTDMSNETPLDGDGDGGDDSFTDEYGADLDNYMDDNSAEYMDYGEPFEPSQLCMDSDFLSYDDLVEESLLGRVGEVTMHIKDRKMIKFLIQSYKRNPFLWDHGNPQFRDRVKRARFLDWIVLEFKSRFNISLAKDAITRKWDNLRTVYKRECNRMALEKTNISTLWYFKELHFLNEVYSYNDKMSDAVVKETSYRRRFSAIWNDTSTAKLLSMVKRYQCFYNRFDPDYRSKERRGEGLHQMAMELQQLIDVTTIQISKRISQLRFDYSKQKMERLNCERLGRKFIANYIYYDQMHFMDEDIPPFKCQHCPEIVQTLRELDLHMLTHQPSLGGGYYCNICTIQFHTAEEFESHKQLHLGAGNEVKFNCELCTASFREKANYDEHLRRHNEELFLPSLAMNHSILEACAADEAKVEPPSGRGRKRSSLAKSLPAAVIKDDEEETTTTAAAAGGTGSDVAKPYGCEVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKSFVARNSLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKVKRYVCQICGSAFAQAAGLYLHKRRHNRPNGAVGAVGRSGRTTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00527561;
90% Identity: iTF_00572118;
80% Identity: -