Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: Hivep2
Assembly: GCA_008044355.1
Location: VNKF01010536.1:59307-66907[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00023 0.019 15.5 0.2 1 23 231 253 231 253 0.98

2 8 0.00023 0.018 15.5 2.9 1 21 259 279 259 283 0.89

3 8 0.027 2.2 9.0 0.1 1 19 600 618 600 621 0.93

4 8 2e-06 0.00017 21.9 2.0 1 23 1305 1327 1305 1327 0.99

5 8 8.5e-06 0.0007 20.0 5.3 1 23 1333 1357 1333 1357 0.92

6 8 0.0001 0.0083 16.6 2.6 2 23 1825 1846 1825 1846 0.97

7 8 0.00058 0.048 14.2 1.2 1 23 1852 1876 1852 1876 0.91

8 8 0.0019 0.15 12.6 2.7 1 23 1897 1921 1897 1921 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00023	0.019	15.5	0.2	1	23	231	253	231	253	0.98
2	8	0.00023	0.018	15.5	2.9	1	21	259	279	259	283	0.89
3	8	0.027	2.2	9.0	0.1	1	19	600	618	600	621	0.93
4	8	2e-06	0.00017	21.9	2.0	1	23	1305	1327	1305	1327	0.99
5	8	8.5e-06	0.0007	20.0	5.3	1	23	1333	1357	1333	1357	0.92
6	8	0.0001	0.0083	16.6	2.6	2	23	1825	1846	1825	1846	0.97
7	8	0.00058	0.048	14.2	1.2	1	23	1852	1876	1852	1876	0.91
8	8	0.0019	0.15	12.6	2.7	1	23	1897	1921	1897	1921	0.92

Sequence Information

Coding Sequence: ATGACGCTACAACAGATGGCAGCAgtcagcagcggcagcagcggcggcggcagcagtaACAAGGAGCCAGTGGCCATAGCCACAAATAACCACAACATCAACACGCCCGCCACCGATGGACCCGCTCTCGGGGATTGGCCCACCAATATCTCGCGGTATCTTCACAAGAAGTTTAAGCGCCTGGCCAGCACCACCGAGGTGGAGAGCAGCGGGTATGGGTCGATGGCGAATGGTGGCCCCTTAACCTCTGATCCAGGTATGCGCACCACCTCGCTGTCCTCAAACAGCTCACTGTCACCGCCACCGATGGTCACCAATGGTCACCACTTGACCCAGCAGctagtgcagcagcagcaaccgccgactgtcgccgccgccacctcAACCACCACACATGAATTCAGTGCCAATTTTGTAAATAGCAATCATGTCAATGCCATTGGTCATGAGGAGAGCAGTAGCCACAAGGCAGCCGTGAATGCGAGAACGCGAACGCCGTTGagtagcagcaacagcagtagcagcaactATGCGGCGAATGCCACTCTCTCGCCGGCCACATTTGCCCAGCACCAACAGCTGACGCAGCCAACAGCGGGAGGAGCAGGGATAGCAGGCGGAGGCGGGATaccaggcggaggaggaggcggagcagcagcagcagcagcagccgttgAGAAGGCAGGACGCTATGTGTGCCCGTACTGCAATCTGATCTGTGCCAAGCCCTCGGTGCTGGAGAAGCATATACGCGCCCACACCAACGAACGGCCATATCCCTGCGACACCTGCGGCATAGCCTTCAAGACGAAGAGCAACCTGTACAAGCACTGCCGCTCCCGGTCGCATGCGGCCAGGGTGCGGGGCCTGGAAGTGCCAGCCGATGCCGACGATGGGTTGTCCGATCAGGATGCTGAGCTGAGCAACAGTAGCTCGGAATTGCCAAGTCGCGCAGGTTCGCCATACGATGAGCCCATGAGTTCGCCCACACCCTCACCCTCCACGCTGTCGGCGGCCAAGAGCGCCTACatccagcagccgccgccactCCCGCAGCACATGCAACAGCTGCCGCTGGGCTCGCCAGCTGCTGGCACCTTGCCGCCCACAACGGCGGACAATCTCCACTCGGCCACCGCCCAGCATCGTCAGTCGATAGACTACAAGCCATATAAGCCCAACACccagatgaagatgaagaacCACATCAACTCGCACCAGCTAcagatgcagctgcagcatcagCTACATGCCCAGCAAACCCTGTTGGCCGCCATGCCGCCAGTGCCGCCAGCCGGACAGCTGGTGCGAGCCAACAGTCAGGTGTCCAGTGTGACGCCAgcccctgccacgcccacgcccgcTGCAGCCGCCAATCTCAGCAGCTTTGCCAGCTCCAGCGGCAGCATGCAAGTGAATGTGGCCAAGGTGCAGGAGCACATATCCAAGTTGATCTCACAGAACGAGGCTATTGTGGAGAACAAGGAGATATTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCTGGCCAAAATGGAGCAGCCGGCCGCAACGGGAGGGCATGTGATGCCTTTGAACTTGTCAGCGAAAGCACAGCCAAAGCCCGCTGTGATTACGGTGCCCGTGAGCTCATTGTCCAACAACAGCTCGGTGCCAGCAGCGACGCCCACCAGTTCTGGCAGCAGCACCTCGAAGGCAGCGCCACCGGCTGGACAAATTAACAATTCGATTATCAAGAACCTGTTGCTGAATGCTCGGGGATTGGCGGTGCCAATTGGCGAGGGCGACGATGCCGTCTACTCGTGCCCGATCTGTGCCAGCGAATTCCGCAGTGCGGACGACTTGAAGCTGCACAACAGCACCTACTGCCAGGACGCGAGCTCCAGTGCACCCATGAGCCCCGCCTCGTCGCCCTTCCGCTCCAACTCGATCTCGTTGAGTCTGCCGGAGCTGAAGAGCCACATGGCCAACTCGAAGAACCCACTGTCGCTGGCCAAGCTGGCGTGGTCGCAGCTGAAGACCAAGAGGAGCACCCTGGTGCTGAGCCGGCTGAGTGCGGCTCAGACGCCGGCGAGAACGTCGACGGTCACTGCAAGCACCTCCACTgccccagctcctgctccagcttctgctcctgcgGCACAGCTGCCCCTTGAGAACCTGCGCTTTGTGGATGCCCCACTGCCATCGCCGGGACCGCTGCTAGGAAAGACACCGTTGGTGGACTATGCCCAGCAGAATGCGCCAAGGAAGGCTCAGGATTCAGTGGTCATTACCAAGATGCACGAGGATCGGCAGTTTGCCAGCTTGGACCTGGAGGCTCAGCCCGCCAAAAGGGTGAAGACAAGCGATCTGGCTTCCTCAACCTCCCAGCAAAGCACAGCCTTCTCCTTTCCCTTCACCAACCACAACAGCGTTCCAGAGCCTCACTCCATCAAAGAGGAGCGCCTGCGCAGGTTCACCTCATCGGGTGGCACCATGATTCCCATTTCGGAGTGCCCTGACCTGGACAACAGCCCCAAGATGATACGCACGCCCTTGCTGTCCGGTGGCAGCTTCCAGGATGTTTCGGTCAAGGTTAGCGATGCTGGAGGATCCAGCAAGGAGCGCAAGCTCATGGCTTTGGTGAGTGGCAGTGGACTGCTCGGCGTCAGTTCGGGCCCCCAGCACTTTCAGTTTCCGCCCATCAACTCGATAACGGCCTTCAATCCACTGACCTTGCCGCCAATGAgcgctggaggaggagcaggtgaTAAGTCCACACCCGTCACGCCCATACCCTATGTGCCTGGTATCCCAGGGCCAGGAAGTCTGACGCCTCAGATGCCGCtgttgccaccgccgccacagcagctccagctgcccGTTCCCTCAGGCCGTGGCCGCAGTCCGAATCGCAAGCAACCCAGTCCGCTGTTGGTTGCTGGCGAACTGAAGGCTCTCTCTCCCTTCGGGGGAGTCCAAAATGTGCCCAGCGAGTTCAGCCGTCAGCCACCGACTCCTGCTCAGCGGCAGGCGCTGCAGTGGAACAGCAAGGAGGCGACGACGCCCAAGAAGGCGCCTTTTAACTTCCTCCGAATGGCGGACAATGTCAAGGCCACCACGGAACCGGAAGTGCGACACTTTAATCTGGACAATGTGATTGCGGGGAAACAAAGAGAGCAGGAGTCGCCCCTAACGCCACTCCATGTGGAAACCCCGAATGGCAATGCCACAGAGGAAGCCACTGCCAGCACCTCGGCCAAGTCAAAGTTCCTGCGACCCACCAGCTTGCCCCTGAAACCCGGAACATTTACGCCAAAGCGTCATCATGGCATAACGCCCACGGCCAATACGTTGCCCCTGATCTCCCCGGAGACCCCAAGACCCTCCAAGTCCTGCGTGCAACTCTATCTCAACGGCCATGCCTACACCTACCTGGGTCTCAAGTGCAGCACCAAGATGTTCTACTGTACAGTGAACTGTCCGCAGCCCTCGTATGTGGCCGGTATGCACAAGCTGTCCATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAACCGCATCCGCTGGGcttcaagctgaagaaggtGATGTCGCTGTATGACTCGCGGCAAAGGATGCTCGGGAATGGCAGCTCCACCGCCATGGCTGGAGCCGGGAAGTTAAGCTACAATGTGGTCTCCTCGCAGCAGACCGTGTGCTCTACGTCCACCTTGGtgagtgccagtgccagctcCTTCTATCAGAAGACGCCGTCAGCGGCTGTGACTGTGTCCGTGTTGAGCGAGGCCAATGTGGCGGCCAAGgccaacgaggaggaggaggcgcaGGCCAAGAAAATGGAGACCAGTCCCTCCGGGCAGCCATTGGTCGGAGGCTATGAGTCGCACGAGGATTACACTTACATACGCGGCCGGGGACGTGGCCGGTATGTGTGCTCCGAGTGCGGTATACGCTGCAAGAAGCCCTCGATGCTGAAGAAGCACATACGCACCCACACGGATGTGAGGCCCTTCACCTGCAGTCACTGCAACTTCAGCTTCAAAACCAAGGGCAATCTGACCAAGCACATGCAGTCCAAGACGCACTTTAAGAAGTGCATTGAGCTGGGCATTAATCCCGGACCCATGCCAGCCGATGGCGAGTTCTTGGATGTGGACATGGACTTTGATCAGCAGTCCTCGACCTCGGCAGGAGGACGCACCTCCTCCATGGCGGGAGAGTCTGATTCCGATGATTACAGCGACAATGAGTCGGAGAGTAGTGATACCGACGAGTCCAAGTCTCGTTTGAAAGAGCACGAGGCCGCCCGGTGCCTGCTGTCGCTATCGATGACGCCGCCCATTCCACAGAGTGTCTCCCCCTATCCGCAGCACCTGCAGGACACACCTCTGCCCGCCGCCAGTCCCGCCAACAGCATTGGTTCCTCGGGCTCGCTGCCCAAGCGCTTGGTGTGTTCGTTCACCTCGCCCAAGCCACCGTTCGACTATCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCCAAGCGCAGCGTGGCCAGCGAGGAGAGTGCTCCCATGGATCTGACCAAGCCGCGTGGCTCCATGTCATCCGCTGTCTCGCCAGCGCCTCAGCCCATTCAGGATCTGCCCAAGTCGCAGGCCCAGCAAATGCACGATGTGATCTTCGGGAGCTCCGGGAATGAGAGCGGCTTCATGAAGACCTTGATCTCGGTGTCGGACAAGGTGCGCATCTCGGCCGAAATGGAGGAGCAGGCCAAGCACGAGGCGGCCGAGGGCGAGGATGTCCTGCTGCAGACCTACATTAAGGAGCAGGCCCTGCATCATGCCAAGCGGAAGCAGAGCCAGTTCAGTGGCAGCTACCTGATCAATCCTTCGTTGTTCTCCACGGCCTCCACGGTGATGAGTTGCAGCGTGAGTAGCAGCAGCGGAAGCAGCCTCCTGACCACCACTAGTAGACCCATTATGACCATCAACGAGGTGCCCAGCATCGAAGTGCACGAGGTGAAGACGCCAGAGGCGGTGGAAATGCCACCAATAGCAGCACCTGTGGTGGCtccacccacacccacatcTGCAGCTACACCTACTCCAATTCCGGTAAAAATTGTCCAGGAAGAGAGTGAGGAATCGGACCAGGAGAAGCCTGTAGGAGAGCCACATAATGCCAATCTGCCAGCTGCAGTGCAGCAGCCGGATGCCAATGATTTTAGCGGAGTTCTCGGACATTCACAATCAGGAGgaacagctgctgctcctcctgccgTCACAGTGGCCACCTCAACACCCGCTCCCGTGACCGTAGCCACCTCAAACTCTCAACCCACTCAGCGCACTGTGATTGTGGGCGAGGATGGCTTCAAGAACGCTTCCACGCCCAGCAGCAAGAGCAGTgatctccagcagcagcagcagcacgttTCCTACGGTCGAGCTGGGCCTGTTCCCGCTCCGCTTCCCGCCAGCGATGCCCGTCCCACCTGCTCCATCTGCGCCAAAACCTTCCAGCGCCAGCACCAGCTGACCCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCCTGCAGCATCTCCTTCCGCACGCAGGGACACCTGCAGAAGCACGAACGCTCCGAGGCGCACAAGAACAAGGTGATGATGACCTCGACCTTTGGCGTGCCCACCACCTCCAATCCGCGGCCCTTCGAGTGTACCGACTGCAAGATCGCCTTCCGCATCCACGGCCATTTGGCCAAGCACCTGCGCTCCAAGACGCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCCTTTGGCACCTACGCGGAGATCGAACGCGCCGGCATCAGTCTCACCGAGATCGATACGAGTGACTGTGAGAATTCGCTGATTTCCCTCAAGTTGCTGGCCCAAAAGCTGCTTGAGAAGGATCCGAACAAGCTGAGTGGATATACCACACCCTCCGGCATGATGCAGCTGGCCCAGGATCCGGCGAATCCTGCCTCGCAGGACAGTGCCTCCGAAGATGGCTTCAGTGCCGCAGTGGCCATAGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCTGGGAACACACCGAAGCGGGCCAGCTCCATGTCCGAGGATGAGACGGTGGCCAATGGCCTGAACCACAACCTGAAGCGTCGCTTGCCTGGGAGTTTCAGCAGCACGGGCGAGGAGAGCGATAACCCGGCGGAGGGCGAGAAGCGAGCTCGCTCCAGTCAGGATCTACCAGCGGTAGCGGTGCCCGTtgccgttcccgttcccgttgctgctgctccggcggCCAGCAACTGA
Protein Sequence: MTLQQMAAVSSGSSGGGSSNKEPVAIATNNHNINTPATDGPALGDWPTNISRYLHKKFKRLASTTEVESSGYGSMANGGPLTSDPGMRTTSLSSNSSLSPPPMVTNGHHLTQQLVQQQQPPTVAAATSTTTHEFSANFVNSNHVNAIGHEESSSHKAAVNARTRTPLSSSNSSSSNYAANATLSPATFAQHQQLTQPTAGGAGIAGGGGIPGGGGGGAAAAAAAVEKAGRYVCPYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARVRGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYDEPMSSPTPSPSTLSAAKSAYIQQPPPLPQHMQQLPLGSPAAGTLPPTTADNLHSATAQHRQSIDYKPYKPNTQMKMKNHINSHQLQMQLQHQLHAQQTLLAAMPPVPPAGQLVRANSQVSSVTPAPATPTPAAAANLSSFASSSGSMQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLNLAKMEQPAATGGHVMPLNLSAKAQPKPAVITVPVSSLSNNSSVPAATPTSSGSSTSKAAPPAGQINNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSTLVLSRLSAAQTPARTSTVTASTSTAPAPAPASAPAAQLPLENLRFVDAPLPSPGPLLGKTPLVDYAQQNAPRKAQDSVVITKMHEDRQFASLDLEAQPAKRVKTSDLASSTSQQSTAFSFPFTNHNSVPEPHSIKEERLRRFTSSGGTMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVSDAGGSSKERKLMALVSGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSAGGGAGDKSTPVTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPVPSGRGRSPNRKQPSPLLVAGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKEATTPKKAPFNFLRMADNVKATTEPEVRHFNLDNVIAGKQREQESPLTPLHVETPNGNATEEATASTSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKKVMSLYDSRQRMLGNGSSTAMAGAGKLSYNVVSSQQTVCSTSTLVSASASSFYQKTPSAAVTVSVLSEANVAAKANEEEEAQAKKMETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQHLQDTPLPAASPANSIGSSGSLPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRGSMSSAVSPAPQPIQDLPKSQAQQMHDVIFGSSGNESGFMKTLISVSDKVRISAEMEEQAKHEAAEGEDVLLQTYIKEQALHHAKRKQSQFSGSYLINPSLFSTASTVMSCSVSSSSGSSLLTTTSRPIMTINEVPSIEVHEVKTPEAVEMPPIAAPVVAPPTPTSAATPTPIPVKIVQEESEESDQEKPVGEPHNANLPAAVQQPDANDFSGVLGHSQSGGTAAAPPAVTVATSTPAPVTVATSNSQPTQRTVIVGEDGFKNASTPSSKSSDLQQQQQHVSYGRAGPVPAPLPASDARPTCSICAKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDPANPASQDSASEDGFSAAVAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHNLKRRLPGSFSSTGEESDNPAEGEKRARSSQDLPAVAVPVAVPVPVAAAPAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00594759;
90% Identity: iTF_00480368; iTF_00483145;
80% Identity: -