Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: -
Assembly: GCA_008044355.1
Location: VNKF01005243.1:10692-12861[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.87 71 4.2 2.1 1 20 129 148 129 149 0.92

2 10 0.00013 0.011 16.2 0.6 2 23 197 218 196 218 0.97

3 10 0.00021 0.017 15.6 0.9 1 23 244 265 244 265 0.98

4 10 0.0009 0.073 13.6 1.9 1 23 272 294 272 294 0.98

5 10 8e-05 0.0065 16.9 0.2 1 23 320 342 320 342 0.98

6 10 7.2e-08 5.9e-06 26.5 0.9 1 23 348 370 348 370 0.99

7 10 0.00099 0.081 13.5 5.5 1 23 376 398 376 398 0.98

8 10 4.1e-06 0.00033 21.0 0.8 1 23 404 426 404 426 0.97

9 10 3.1e-05 0.0025 18.2 0.3 1 23 430 452 430 452 0.99

10 10 0.0058 0.48 11.1 0.1 3 23 478 499 477 499 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.87	71	4.2	2.1	1	20	129	148	129	149	0.92
2	10	0.00013	0.011	16.2	0.6	2	23	197	218	196	218	0.97
3	10	0.00021	0.017	15.6	0.9	1	23	244	265	244	265	0.98
4	10	0.0009	0.073	13.6	1.9	1	23	272	294	272	294	0.98
5	10	8e-05	0.0065	16.9	0.2	1	23	320	342	320	342	0.98
6	10	7.2e-08	5.9e-06	26.5	0.9	1	23	348	370	348	370	0.99
7	10	0.00099	0.081	13.5	5.5	1	23	376	398	376	398	0.98
8	10	4.1e-06	0.00033	21.0	0.8	1	23	404	426	404	426	0.97
9	10	3.1e-05	0.0025	18.2	0.3	1	23	430	452	430	452	0.99
10	10	0.0058	0.48	11.1	0.1	3	23	478	499	477	499	0.98

Sequence Information

Coding Sequence: ATGTCAACGCACAACGAGCCCGAGGAGACTAGGTCCCACATGCATGTGGAGGACGGACTCTCGCCCAGATGTGGAACAACCCATGAGCTCCTCTTCTACTGCGAGAGCTGCACTAACATCTACGAGGACAGGGAGGCTTACGCCAAGGACCACAGCCAGCAGCCCGGCTGCTGCGGCGGTGGTATCAAGGAAGAGTTTGAGTTTGTAGAGGAGATAATTGCAGACGATCAGGCCGAGGAGGTCACACCAGGTAGCACGTTGGCCGAGGAGGATCGTGAAGAGGAGATCCTCGAAGCTGACGTGCCGCTCTGGGAGGTGGTAGAGGACACTTCTGCCTCCATTAAGGTGGAACCGAACGAGACTGACACAAGCCATTCGGATCGATATTTTTGCTATGACTGTCACAGCATTTTCGAGAACAGAAGCAGCGCGGAGGATCATGTTTGTCCGCAGGCAGAGTCTGGCGGTGGCTGCATCCAGCACGCAGTTGAAGCTGCCGCAGGCCCAGACAAGCCATCGCCACGCCGCAAGTTACCCAGCGTGGCAGCAAGGTCGGACTCTAAGAGTGGGGCACAATCCAGTGTCATTAGCTGTGAAATATGCAACACCGTTTTTAGCACTGCCAAGTTTCTCAAGTTCCATATGCGCATTCATGAGAAGGTCGTGTCCAAGAGCATTCAAGACGCCCTTCCCGTGGGCGCCCACCAGCAGTACAGTGAGCTGGATCAGTTTTATTGCGAAATTTGCAACAAGAGCTTTGACGAGAACCTCCTGACGGTGCATAAGCAAATGCACCAGCAGACCACCAAAGAGTTTATGTGCAGCATTTGTAACCGCCAATTCTACAACGCCATAGACTACCACATGCACCTTAAAATTCACCAGAAGCCGCGCGATGTGGATGCCGCCAAGATTTCGGAACATCGCGGCAGTGGTGGCGAAAAGGAGAAACCGGGCTTTCCCTGCCAGTACTGCGAGCGTGTGTTCCCTCGCCCCTACGAGAAGGTCAAGCACGAACGTGTGCATACGGGCGAGAAGCCCTACTCCTGCGAGGTGTGCGGCAAGACCTTTCGCGTCTCCTACTCCCTCACCCTCCATTTGCGCACTCATACGAACATTCGTCCATATGTGTGCACGGTGTGCAATAAGCGGTTCAAGTCGCATCAGGTGTACTCCCACCACCTGCGGATCCACAGCTCGGAGCGGCAGTTTGCCTGCGACGTATGCTCAAAGTCCTTCCGCACCTCGGTGCAACTTTACGCCCACAAGAATACCCACACCAAGCCATACCAGTGTGTCCTTTGTAATCGTCCCTTCTCGTCGATGTATGCCGTAAGGATTCACATGCAAACACACGAGGAAGAGAAGAGAAAGGAAGGTGGAAAAAGCGTTCAGACTACCAAGAACCAAGCGTCAGCTGGGAAATTCTGGTGCAGTTCCTGTGGAGCAGAGTATGCCCGCATGTTTGCCCTGCGGCTGCACATGAAGACAGCTCACGGCCTGGTGGAGGAAGTGATACAGGACGAGGATCATTCATCTTCGGCCCCAGAAGATGTCcttgccaccgccgcccacaCGGACTCTGAGACTGCAGTGCTAATAGCAGCCGCCGAGGCTGACGCTGCCTATATCAACGCTGTGGTGAACGATGTCGATGTAGTGGGATCCGTGCCCACATACGAAGAGGTAGCCGTAGAGTTCGATGTTGATAACTTCCACAGCGAGGAGATCATCACGGATTGGCTTAAATAG
Protein Sequence: MSTHNEPEETRSHMHVEDGLSPRCGTTHELLFYCESCTNIYEDREAYAKDHSQQPGCCGGGIKEEFEFVEEIIADDQAEEVTPGSTLAEEDREEEILEADVPLWEVVEDTSASIKVEPNETDTSHSDRYFCYDCHSIFENRSSAEDHVCPQAESGGGCIQHAVEAAAGPDKPSPRRKLPSVAARSDSKSGAQSSVISCEICNTVFSTAKFLKFHMRIHEKVVSKSIQDALPVGAHQQYSELDQFYCEICNKSFDENLLTVHKQMHQQTTKEFMCSICNRQFYNAIDYHMHLKIHQKPRDVDAAKISEHRGSGGEKEKPGFPCQYCERVFPRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTVCNKRFKSHQVYSHHLRIHSSERQFACDVCSKSFRTSVQLYAHKNTHTKPYQCVLCNRPFSSMYAVRIHMQTHEEEKRKEGGKSVQTTKNQASAGKFWCSSCGAEYARMFALRLHMKTAHGLVEEVIQDEDHSSSAPEDVLATAAHTDSETAVLIAAAEADAAYINAVVNDVDVVGSVPTYEEVAVEFDVDNFHSEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00613632;
90% Identity: iTF_00480322;
80% Identity: -