Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: ZNF296_1
Assembly: GCA_008044355.1
Location: VNKF01013397.1:113059-117504[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0017 0.14 12.8 1.5 1 23 207 229 207 229 0.96

2 25 1.5 1.3e+02 3.4 3.7 1 21 236 256 236 258 0.84

3 25 0.005 0.41 11.3 0.7 2 23 290 311 289 311 0.96

4 25 0.00045 0.037 14.6 0.8 1 23 382 405 382 405 0.94

5 25 3.9 3.2e+02 2.2 3.3 1 20 446 465 446 467 0.91

6 25 0.013 1.1 10.0 0.1 2 23 476 497 475 497 0.96

7 25 0.0038 0.31 11.6 1.1 1 23 579 602 579 602 0.96

8 25 0.0076 0.62 10.7 0.3 2 22 612 632 611 632 0.93

9 25 4.4 3.6e+02 2.0 8.5 1 23 641 663 641 664 0.94

10 25 0.0012 0.096 13.2 1.4 2 23 679 700 678 700 0.97

11 25 4.5e-06 0.00036 20.9 4.3 1 23 707 729 707 729 0.98

12 25 0.0006 0.049 14.2 1.0 1 23 864 887 864 887 0.96

13 25 0.015 1.2 9.8 0.6 3 22 896 915 894 915 0.93

14 25 0.022 1.8 9.3 1.4 1 23 924 947 924 947 0.93

15 25 8e-05 0.0066 16.9 2.3 2 23 966 987 965 987 0.97

16 25 8.3e-05 0.0068 16.9 0.4 1 23 994 1016 994 1016 0.98

17 25 0.038 3.1 8.5 0.0 2 21 1043 1062 1042 1063 0.92

18 25 0.0022 0.18 12.4 3.0 1 23 1109 1132 1109 1132 0.97

19 25 0.013 1.1 9.9 0.6 1 23 1169 1192 1169 1192 0.96

20 25 0.00026 0.021 15.3 1.5 1 23 1218 1241 1218 1241 0.97

21 25 4.9e-06 0.0004 20.7 0.2 2 23 1269 1290 1268 1290 0.95

22 25 0.0025 0.2 12.2 2.6 1 23 1296 1318 1296 1318 0.99

23 25 1.9e-06 0.00016 22.0 2.0 1 23 1324 1346 1324 1346 0.97

24 25 1.7e-07 1.4e-05 25.3 2.4 1 23 1352 1374 1352 1374 0.99

25 25 0.0011 0.093 13.3 0.1 1 21 1380 1400 1380 1404 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0017	0.14	12.8	1.5	1	23	207	229	207	229	0.96
2	25	1.5	1.3e+02	3.4	3.7	1	21	236	256	236	258	0.84
3	25	0.005	0.41	11.3	0.7	2	23	290	311	289	311	0.96
4	25	0.00045	0.037	14.6	0.8	1	23	382	405	382	405	0.94
5	25	3.9	3.2e+02	2.2	3.3	1	20	446	465	446	467	0.91
6	25	0.013	1.1	10.0	0.1	2	23	476	497	475	497	0.96
7	25	0.0038	0.31	11.6	1.1	1	23	579	602	579	602	0.96
8	25	0.0076	0.62	10.7	0.3	2	22	612	632	611	632	0.93
9	25	4.4	3.6e+02	2.0	8.5	1	23	641	663	641	664	0.94
10	25	0.0012	0.096	13.2	1.4	2	23	679	700	678	700	0.97
11	25	4.5e-06	0.00036	20.9	4.3	1	23	707	729	707	729	0.98
12	25	0.0006	0.049	14.2	1.0	1	23	864	887	864	887	0.96
13	25	0.015	1.2	9.8	0.6	3	22	896	915	894	915	0.93
14	25	0.022	1.8	9.3	1.4	1	23	924	947	924	947	0.93
15	25	8e-05	0.0066	16.9	2.3	2	23	966	987	965	987	0.97
16	25	8.3e-05	0.0068	16.9	0.4	1	23	994	1016	994	1016	0.98
17	25	0.038	3.1	8.5	0.0	2	21	1043	1062	1042	1063	0.92
18	25	0.0022	0.18	12.4	3.0	1	23	1109	1132	1109	1132	0.97
19	25	0.013	1.1	9.9	0.6	1	23	1169	1192	1169	1192	0.96
20	25	0.00026	0.021	15.3	1.5	1	23	1218	1241	1218	1241	0.97
21	25	4.9e-06	0.0004	20.7	0.2	2	23	1269	1290	1268	1290	0.95
22	25	0.0025	0.2	12.2	2.6	1	23	1296	1318	1296	1318	0.99
23	25	1.9e-06	0.00016	22.0	2.0	1	23	1324	1346	1324	1346	0.97
24	25	1.7e-07	1.4e-05	25.3	2.4	1	23	1352	1374	1352	1374	0.99
25	25	0.0011	0.093	13.3	0.1	1	21	1380	1400	1380	1404	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCGAATATCTGCCGCACTTGTGCGCTTCAGAACACGGATCTGCGGCCATTGTCCAGTTGTCTGGCCAAGGACGCCTCAAAAAGTTTCTATGATGTACTCCGGGAGCTAACCCAAATCGATCCCCTGGTGGGGAGCTCTGATGACAATCTGCCGCAGCATCTGTGCACCGAATGCTTAGCGAGACTGGAAAGTGCCTACGCCTTTGTGGAGCAGGCCAGAAAGGTCAATGGAGAGCTGTTGGTTCGCTTGCGGGAGTGCCTGGACGAAATGCCCATAGATATtccgcaggagcagcagcaaatcaAAACCGAAGTAGACATCGATGAAGGGACTCTAAAGGAGGATGTGGATTCCACTGAAACGTCGCCTGTGGAGTTCAAATGGCAGCCGGAAAGTGGCAGCGATGAGGAGTCTGGTGGAGCCGCAGCCGGTGAAGAGAATGAGGTCGAGAAGAAGCCCTATTCCCTGCGACGCAGCGCGCGCAAGATCAAGCAGCCGGTGGAGAGCGACAATGAGGACTTAGTACCCACGGAACCATCGCCCACTAAACGCCGTCGTGGACGTCCGCCGGGCCCGGCCAAGCGCCAGTCAATGACCTCCGACGGACGCCACGCCTGCAAGGTGTGCGGCAAGACCTTCTCCTGGTTCCGTGATATGCAACGCCATGCCCGCATCCACTACGAGAAATCCAATGCCTACGTGTGCGACACCTGTGGCAAGGGATTCCTGCGCAAGGACAAGTACACATTCCATTTGCGCTGCCACGAAAAGCGCGATGCCAAAGGGAGGGCTCTGGAGCTGGGCAGCGAGTGGCGTTTCGCCGAACGGCTGTACAGTTCCGGGAGGCTGAAGCGGATTGAGTGCAAGCTGTGTGGCCTCAAGTGTCCACGAATCCAGGAGCTAAGAACTCACATGGTCAGTCATCGGAACGTGGAGAGTTTGCGGCAGCTGAAGGAGGATAGCGATGTGATCAGGGAGCACTACGCAGAACAGCCTCTGGACGACGTCAGGCAACAGATTATCATGGACATTGCGGCGGGCGACTTGGAGAAGTTTGCTTCCGTGGTGAACTACCATGGCTACGAGCTGGGATTGTGTGACTCGGACGAGGAATCGGCCAGCGAGGAGGCCAAATATGAGTGTGAGGTGTGTAAGCTTGCCTTCTCCCGGAAACACCAGGTGGTGAGGCACACGCTGGAGGAGCACGCACACTCCTCGCCCTCAGAGCTTCCCTGGCAACGCTGCAGTCTCTGCAAAGTTGGATTCCTCTGCTCCAGACTCTACGATTGCCATGTCCGCACCCAGTGTCAGAGCAAGGAAAGGCGGCACTGCTGCCCCAAGTGCCCGGGGAAGTTTATGTGGCGGGAGAACCTGCAGAGGCACGCCTGCTCCAAAGCGACCTTTGCCCGCCAGATCTCCTGCTCTTTGTGCGATGAATCGCTGCCCACTTTGGCCAAGTTGCGCATACACCTGGTTACCCACCAGAATGAACTGTGTGGTATCGATCCCAAGCACACTTCCACGTTCTTCCGGTCGTTCTACCCCGAGGGATTGGACTGCACGGCGGAGGAACTGGGTGTTCGCTTGGCTGAGGACTTTGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAGGAGCTGGATCTCTTCGACTCCGAGACTGAGCAGAGCGGCGATGATGCTGGTGAGGAGCGTGAGAAGCCCGTCTCCCACACGTGTCTTCTGTGTGGCAAGGTCACAAACAGACTCCTGAGCTTGCTGCAGCACCAGAACAGCGACCATTCAGAGGCGGCCACAGAGTTGCTCTGTTCCTGCCAGGATTGTGGAGCTGGCTTTGTAAGCGACGCTCTGCTCCAACAGCACCGCCGTCGGGTGTGCGCCAAGAAGCACTTCCGCCATCACTGCCAGAGCTGTAATCTTCGATTCGTGTGGTTGAGCAACTACGAGCATCATCTGAGGAGCCACCACAaccaggcggaggaggaggagccacccGAGGAGGGCAAACTGCAATGCGATGAGTGCGAGAAGGTCTTCATCTGGCACAAGGATCTCACGCGGCACAGGCGCTTGCACCAGCCGCAGTCGGCGCAGTTCGAGTGTCCCCATTGCGATCGCAAGTTCCACCGCAAGGATGGCCTAAAGTCCCATCTGCGGGTGCACACGGAAGAACAGCAGGTGGAGCAGCCTTTCACGTCCGACAGTGATCGGGTGCTGGCCCTGCTCACTCGTCCTCATGGCTGCAAGCAGATCCAGTGCATGATATGCCTCTCGCGGCACTCCAAGATCTCCGATCTGCGCACGCACCTGGCCACCCATCAGTACGGATTGAGCTTCTCCCCCGAGACCGATAGTTTCAGTGTCTCAAAGTCCCTCTACCCGGAACTGGGAACGGCCTTGGGCAGAGATGAACTATCCGAGAGGATTATGGCAGATGTCGTCCAGGGACTGGAGCTAGATCGATTCACTTCCATTACGAACGAGGCTGGCCTCGAACTGAACTTGGATAGCAGCGAAACTGAGACCGAATCCGAGCAAGAGGAGGAAGACCCATCCAGCCAGAAGTACGCCTGCAGTCTCTGTCCCACGGCTGTGAAGAGGAAGCACCAACTCTACGCCCACCAAAGGGAAACTCATCCGTGGGAGGAGGCCCCCCTCGCTTGCCTGCACTGCCAGGCTAGGTTCGTCAACGAATCCCTGCTGGAGCATCACTCCAGAACCCTTTGCGGCAATCCCCAGAAGCGCTTCCAGTGCCGAAAGTGTCCGCTTCGCTTCCGCTGGCGTGAAAACCTCAAGCTCCACCTGTACCTGTCCCATCAGCAGGCTGAGATCCAAGCTACGGAAGACTCGGCGCCAGCGGAGGCCGACCTGCAGTGCCGGGAGTGCCAGCGAACGTTCAAGATGCAGAAGGATCTCACGCGGCACACGCTGATGCACGCCCGCGAGGCGACGATCTACCGGTGCCGCTGGTGTGCCCGCCGCTTCTACCGCTGGGCCAATCTCCTGCAGCACATCGCACGCCACGGCATCCGGGCCAGCCAGTTGCACTACGCAGAGGCTCTGCTGGACTCCTACGGCAATCCAGGCGGGCAGAAGACGGTAGAGTGTCGCGTGTGCAATGTGAGCTTCTCCAGCATCGCTGCCCTGCGCCTGCATCTGGAATCCATGCCGGCGGGAAGTCACCACGAGCTCTCCTCGCTGAAGAACTACTCGATCACCAACCAAATGGGCTTCGAGTTGGATCTGCAGGACTCGGAAACGGATGAGGAGCAGGGGAAGCCTCCGGGAGTGCCTGCCTATTACACGTGCGGCATGTGCCAGCTTCGATGCGTGCGGAAGTtcgagctgcagcagcaccagcagtcCATGCACCGGCTGGAGAAGATCCCCGACGGCTGCGATCAGTGCATCTTCAAGAGCGTCTGTCCCGACCTCATTGCCCACCACAAGAGGACGCAGTGCGGCAACCGGGAGAAGCAGTTCACCTGCGTTCGCTGCGGCTACAAGTTCATGTGGGAGTCCAACCTGCTCACGCACATGCAGCTGCAGCACGGAAAGCTGGACAATCTCGAGCCGGAGGAGAGCAAGGAGGCTGCGACGGAGGAGCAGAAGCCTGGTAGCCCGGTCTTTCAGTGCGGCCTCTGCCCCAGGAAGTACAATCGCAAGGATCGCCTGACAGCGCACGTGAAAAAGTTCCACGGGCCCGATGGCAGGGGCCCCGAGGTGGTAAAGGTTCCTCCTCCCAACAGACCCACCTCCCCCAAGGAACCGAAGCGCTTCCTCTGCGCCTTCTGCGGCAAGGCggtcagctcctcctccaaccTGATCATCCACATGCGCCGCCACACCGGCGAAAAGCCCTTCAAGTGCGAGTTCTGCGCGATGGCCTTCCCCCGATCCTCGGACCTCCAGTGCCACCGACGCACGCATACGGGAGAGCGGCCGCACGTGTGCACCGTGTGCCAGAAGGGATTCGCCCGCTCCTataagctgcagcagcacatgCGCATCCACAGCGGCGAACGGCCCTACAAGTGCACCTACTGCGAGAAGAGTTTCACGCAGTCCAACGACCTGACGCTCCACATCCGCCGACACACGGGCGAGCGGCCCTACCAGTGCGGCGTCTGCGGCGAGCGTTTCATCCAGGGAACGGCGCTGAAGAACCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGAGCTCTGGGGAGCCGGTCAGGCGCACGGTCTTGGAGCAGTTTACTGTATGA
Protein Sequence: MLPSNICRTCALQNTDLRPLSSCLAKDASKSFYDVLRELTQIDPLVGSSDDNLPQHLCTECLARLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQQQIKTEVDIDEGTLKEDVDSTETSPVEFKWQPESGSDEESGGAAAGEENEVEKKPYSLRRSARKIKQPVESDNEDLVPTEPSPTKRRRGRPPGPAKRQSMTSDGRHACKVCGKTFSWFRDMQRHARIHYEKSNAYVCDTCGKGFLRKDKYTFHLRCHEKRDAKGRALELGSEWRFAERLYSSGRLKRIECKLCGLKCPRIQELRTHMVSHRNVESLRQLKEDSDVIREHYAEQPLDDVRQQIIMDIAAGDLEKFASVVNYHGYELGLCDSDEESASEEAKYECEVCKLAFSRKHQVVRHTLEEHAHSSPSELPWQRCSLCKVGFLCSRLYDCHVRTQCQSKERRHCCPKCPGKFMWRENLQRHACSKATFARQISCSLCDESLPTLAKLRIHLVTHQNELCGIDPKHTSTFFRSFYPEGLDCTAEELGVRLAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDAGEEREKPVSHTCLLCGKVTNRLLSLLQHQNSDHSEAATELLCSCQDCGAGFVSDALLQQHRRRVCAKKHFRHHCQSCNLRFVWLSNYEHHLRSHHNQAEEEEPPEEGKLQCDECEKVFIWHKDLTRHRRLHQPQSAQFECPHCDRKFHRKDGLKSHLRVHTEEQQVEQPFTSDSDRVLALLTRPHGCKQIQCMICLSRHSKISDLRTHLATHQYGLSFSPETDSFSVSKSLYPELGTALGRDELSERIMADVVQGLELDRFTSITNEAGLELNLDSSETETESEQEEEDPSSQKYACSLCPTAVKRKHQLYAHQRETHPWEEAPLACLHCQARFVNESLLEHHSRTLCGNPQKRFQCRKCPLRFRWRENLKLHLYLSHQQAEIQATEDSAPAEADLQCRECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASQLHYAEALLDSYGNPGGQKTVECRVCNVSFSSIAALRLHLESMPAGSHHELSSLKNYSITNQMGFELDLQDSETDEEQGKPPGVPAYYTCGMCQLRCVRKFELQQHQQSMHRLEKIPDGCDQCIFKSVCPDLIAHHKRTQCGNREKQFTCVRCGYKFMWESNLLTHMQLQHGKLDNLEPEESKEAATEEQKPGSPVFQCGLCPRKYNRKDRLTAHVKKFHGPDGRGPEVVKVPPPNRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRLQQGHYEEGQSSGEPVRRTVLEQFTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00606462;
80% Identity: -