Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: -
Assembly: GCA_008044355.1
Location: VNKF01010087.1:1-10016[+]

Transcription Factor Domain

TF Family: THAP
Domain: THAP domain
PFAM: PF05485
TF Group: Zinc-Coordinating Group
Description: The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2e-12 2.8e-09 37.7 5.3 1 85 12 80 12 82 0.82

2 18 1.6e-12 3.7e-09 37.3 0.1 1 86 105 173 105 174 0.83

3 18 8.9e-14 2.1e-10 41.3 2.4 1 87 320 389 320 389 0.80

4 18 1.2e-06 0.0029 18.4 0.3 23 86 466 517 452 522 0.72

5 18 2.2e-13 5.2e-10 40.0 0.9 1 87 570 640 570 640 0.83

6 18 7.4e-11 1.7e-07 31.9 0.1 1 86 675 749 675 750 0.80

7 18 8.9e-12 2.1e-08 34.9 0.0 1 86 760 833 760 834 0.79

8 18 1.3 3e+03 -0.9 0.2 1 8 858 865 858 874 0.90

9 18 0.011 25 5.8 0.0 50 62 879 895 865 917 0.70

10 18 5.7e-06 0.013 16.3 0.1 1 58 923 973 923 997 0.81

11 18 5.9e-12 1.4e-08 35.4 0.3 1 87 1013 1085 1013 1085 0.81

12 18 5.4 1.3e+04 -2.9 0.1 20 45 1091 1112 1089 1120 0.68

13 18 9.7e-16 2.3e-12 47.6 0.6 1 86 1197 1269 1197 1270 0.81

14 18 7.3e-13 1.7e-09 38.3 3.4 1 86 1335 1405 1335 1406 0.80

15 18 1.1e-13 2.5e-10 41.0 3.1 1 86 1498 1568 1498 1569 0.84

16 18 1.4e-11 3.2e-08 34.3 0.1 1 86 1647 1716 1647 1717 0.83

17 18 9.1e-11 2.1e-07 31.6 0.8 1 58 1742 1790 1742 1799 0.84

18 18 2.3e-10 5.4e-07 30.3 0.7 18 87 1808 1866 1797 1866 0.74

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2e-12	2.8e-09	37.7	5.3	1	85	12	80	12	82	0.82
2	18	1.6e-12	3.7e-09	37.3	0.1	1	86	105	173	105	174	0.83
3	18	8.9e-14	2.1e-10	41.3	2.4	1	87	320	389	320	389	0.80
4	18	1.2e-06	0.0029	18.4	0.3	23	86	466	517	452	522	0.72
5	18	2.2e-13	5.2e-10	40.0	0.9	1	87	570	640	570	640	0.83
6	18	7.4e-11	1.7e-07	31.9	0.1	1	86	675	749	675	750	0.80
7	18	8.9e-12	2.1e-08	34.9	0.0	1	86	760	833	760	834	0.79
8	18	1.3	3e+03	-0.9	0.2	1	8	858	865	858	874	0.90
9	18	0.011	25	5.8	0.0	50	62	879	895	865	917	0.70
10	18	5.7e-06	0.013	16.3	0.1	1	58	923	973	923	997	0.81
11	18	5.9e-12	1.4e-08	35.4	0.3	1	87	1013	1085	1013	1085	0.81
12	18	5.4	1.3e+04	-2.9	0.1	20	45	1091	1112	1089	1120	0.68
13	18	9.7e-16	2.3e-12	47.6	0.6	1	86	1197	1269	1197	1270	0.81
14	18	7.3e-13	1.7e-09	38.3	3.4	1	86	1335	1405	1335	1406	0.80
15	18	1.1e-13	2.5e-10	41.0	3.1	1	86	1498	1568	1498	1569	0.84
16	18	1.4e-11	3.2e-08	34.3	0.1	1	86	1647	1716	1647	1717	0.83
17	18	9.1e-11	2.1e-07	31.6	0.8	1	58	1742	1790	1742	1799	0.84
18	18	2.3e-10	5.4e-07	30.3	0.7	18	87	1808	1866	1797	1866	0.74

Sequence Information

Coding Sequence: GCTAAGATCAAGAGATCTATTTCGGATCTAAAgtgttgtgtacacagctgtaGAAGAAGCCGTTTGGAGCACGGAGCACAGCTGTTTCCCTTTCCAACGGGCAAGCAGCAACACCTAAAGTGGCGTCATAATCTGCACCTGGAACCAGAGGAGGTGAACCGATCAACGCGAGTATGCAGTGCTCACTTCAATCGGCGTTGCATCGAGGGCAAACAGCTGAGGAGCTGGGCGATGCCCACCCAACAATTGGGTCACCACGACCAGCCGATATACGAGAACCCAAAGAATATACCTGGGTTTTTCACACCAACCTGTGCCCTGGGACACTGTCGCAAGAGGAGGAGTATTGACAACGATCTGCGTACCTATAGATATCCTAGAAGCGAAGATCTGCTGGAAAAATGGCGAGTTAATTTACAGCTGGCTCCGGATCAGTGCCGTGGTCGGATTTGTGCAAACCATTTCGAGCCGCAGGTGCGGGGCAAGCTAAAGTTAAAGACGGGAGCCGTGCCCACACTAGAACTTGGACATGATGATGGAGTAATCTATGACAATGAGGCTATAAAGACGGGTATGATGGAGGAAGAGGAAGGCCTCACCACAGAATTCCAGCGCCTGAAACCAAAAAATGAGATGTTTGAAGTGGTTGAAGAGGACGTTGGAGAGAATGTTGGTGAAGAGCAGCACCCAGATTACCAGGACGAAAATGCAGATGAGGATGACAAGGATGACCAATATTTTGATCCTCTTGAACTGGTAGAGACCTTTGAACATCGCAGCAATGATGACGCCcaagatgatgatgaagaaGAGGGCCGAGTTCTGGACTCCCCCTCTGGTTACATGGTCAAGAAGGAGATAGAACAGCTTCCAAGCAGCCCACCTTCACCTTCACCTTTACCCCTACGGCACCAAACTCTGCGTCAAGGCAAGCCTGCCAACAATGTGACGCCCATTTGTTGTCTAAAACACTGCAGGAAGGAGCGTACTGCCTTCCACCTGCTGAGCACTTTTGGTTTCCCAAAGGATCGTCAATTGCTGCTGAAGTGGTGTGCCAATCTGCATCTAAACCCGGATGACTGCGCCGGCCGGGTTTGCATCGAACACTTCCAGCCGGAGGTACTCGGTACCCGTAAGCTAAAGCAGAACGCGGTGCCCACTGTTAACGTTGGACATGATGAGCCGCTTAGGTACTCGTGTCATGGCGTGGATCAGAACCTCGAGGACCAAGACCCACAGCCACAGCATTCGGTTTTTCGGCTTTGGAGCCTGAAACACTGCCGCAAAAGGAAGCTAACGGAGCCACCGGATATTGCCCTGGCCAAGAGGAAACCGCTGGGAATGCCGATAATGAAGCGGGAATGGGAGATGGAGAAGTCAAAGAAGATGACTCAAGCAGACAATAACAAAGAGGTGCTGTCCAAGTGGCTGCACAACACCAAGATCCCCTACGATCCTTCTAGGCACCGAGGCTATCGCATCTGCGGGCTGCACTTTGAATCAGAGTACTTAGAAGCGGATTGGCCGCTACAATGGGTTATACCGACGCTCCATCTAAACCAAGAAGATGAGATCTACTTAAATAGTAAGCCCTTGCAAGAGGACCAGCTCTTAATGTTGGCTCCACTGCGGATAAAGACGGATCTAGCCTTGCTGGGTAGTCCGAGTGCAAGTGCAAGCCCCAGTCCTCGCGGCAGGATCCGGATATGTTGCATTCCCACATGTGGTCAGTTTGGAAGCAATCAAGTAAGGCTCTATCGCTTTCCGACCGAGGAGCAGGCGTTGCTTAGGTGGTTGGTGAACACGCAACAGCAGCCAAGACTCGTAGACCCCAAGGACTTATATGTGTGTCAGTCGCATTTTGAGCCTGAGGCCATTTGTAAGAAACAGCTTCGCAACTGGGCAGAGCCCACATTGAACTTGGGGCACGACGGTCACGTGATTCCAAATGCCAAACACAATGGCAACATTTCTGATAGCCAGGATACCGAGCAGGCAATGAAGTTCATTCGCGAACGATTCTGCTCCGTCATATCTTGTTTTCAGGCAGGAGGACCGGAGGAGGGAGAAGTGAGGCTATATGATTATCCCGAAGATATGGCTACTACTCGAAAGTGGGCAGCCGCTTGCAGACATCGCTCCATGCAGGCCAGGAGCCATGGGTTCAAGGTATGCCAGTTTCACTTCGCTACGGAATGCTTTGACCCAGATACTGGAAAATTGACTGAGGGTTCGGTCCCCACACTGGAGTTGACCAGAGATGATATGGAAAGGCAGTGTCTTGTAGCTGGATGTGTAAAGATTGATCCTAATGGGGCCCGTCTTCGCTACTACAAGATACCAAAGACTGCTGCTCAATTGGAAGCGTGGAGCAACAACCTTAAGATCCATCCCACGGTTCTAATGCAAGGGGAACAGCAGTACATCTGCGAGAAACACTTTGAAGCGTTCTGCTTTGGAGCTAACAAAGGACTGCGTTCTGGTGCCCTTCCAACTCTCTTGCTGGGTCATGATGACGTAGATTTGCTTCCAAATCCGGAAAGTCTCTTCTGCCAGAGCAAGACGGACAAGTGCTGCGTTCCAGGTTGCGGACGTATCTGGCAGGCTGGCGATCCGACCATGGATGAACTGGGAAAGCTTAAGGTCTGCAGTGCTCACTTTGAGAGTTCTGCGATACCCACCGTGGAATTGGGTCATTCTTCTCCGGATATTTACCAAGCGGATTTACCAAGCTTAAAGTCCCAAAAGCGGTCCGTAAAGGTCTATTGCTGTTATCCCAAGTGCGAGGAAATCAGTCTTTCCAAGAATCTGTATTATGGGCTTCCCCAAGAGAAGCATCTGCGAAGTGCCTGGTTAAGGCACATGAACATTGAAGATCCGAAAGATGGAGCAGTCGCAGAGCTTTGCCCGCTGCACTATGTCATTCTCTACCAGCACAGTGCCAAAAACTATCCTGAGTATCACGATTCAAACCGATTGTTTCTTGATGATAACTACAAGGATGCGCGGAACAACCGGCGCGTAAGGATTGTGAGCTGTGTGATCAAGGGCTGCGACATGGTTAAGCCACGGGATGGGATACCATTGCACGGGATGCCGCAGAACCAGGACATCCTGCAGATGTGGATAGATAATGGTCAGTTTGAGTTCTTAGAGCAGCAGCGGTACATGCTTAAGGTGTGTCACAACCACTTTGAGCCATGCTGTTTCTTCGACGATAGACGCTTGCTCTCATGGAGCGTGCCGACTCTGCACCTACCTGGCGAAGCATTTCACCAAAATCCTACCGCCGAACAGTGGCAAAACATGGTCAAAAAACAATCAGCAGCCAAAACAAATGCAGTGGAGAAAGAGGAGTCTGAGCTATATACGGATGAGGATAGGACGGAGcccattttaaaaatggagCATATTGAATCTGAATATGAAGATAAAAACTCGGAGATGCAGGCCCTAGAAGTCCTCCTGGAAGTTGGGCATGTGGAACGAATGGAGAGCTATGAGAAAGTGGATAAATCACCGGTTATCTATACCGAAAATGCACCCTTCCGATCGTCACCAATACGTGGCCAATACAATGCTAATCAGTGTGCCGTAGAGGGATGCCAGGTGACCGTCGAGGATGTGGACGGCACTATTAAACTGCACAAGTTCCCCGCGTCGCAGGAAGCCGCACAAAAGTGGAAGCACAACACCCAAGTTGACATGGACGAAAAGTTCTGGTGGCGCTACCGCATATGCAGTTACCACTTCGATCAGGAGTGCTTTCAGAGCGCTAGGATTCGAAAGGGCGCGATGCCCACGCTTTTGTTGGGACCTCAGCGACCGGATAAGGTCTACGATAATGAATTTGCACAAccagaggcagaggcggaAGAGTCTTTTTTAGAGCCACCGGGAATTCAGCTGGAGGAAGGATGTACGTCTGTGTCTAGAGTTCGAAAGGAGGTTTCTAGTTTATGCCTGCCGCCACGGGCGCCGCCTCGAAAGTCGAGCAAGTTTTGCCAGATTTATTCTTGTACGAATCACCTGACAACTGAGAACATGACACTCCACAAGTTTCCCCACTCAGAGGACATGTGCCTTAAATGGCAGCACAACACGCAAGTGCCATTCGATCCCTACTACCGCTGGCGTTACCGCATCTGCAGTGCCCATTTCCATCCAGTGTGTTTGGTCAACATGCGTCTAGTCCACGGAAGCGTTCCCACTTTAAAGCTAGGACCCAAGGCTCCATCCGAACTGTTTGACAACGACTTTAATGCCATCAACCTAAGGCTGGACAAAAGGTTGACGGAGTCCAATGCCAATGTGTATATCAAGCATGAAAAGAGGGAAGAGGGTGAAGGCTCGCCAATTTTGCTGGAGCCCGAGCTCCAGTTTCAAGAGGATCAAGACGATAGGATATCAGCATGGAACAGCAAACTGCAATTGCGACCTATAAAGCTGGAGAAAATAAGTTATAGCCAGAAGAAGTTTGGCTCTGATAAGTGTTTGCTGGCTCACTGCCAACGCCAAAGGTTCCAACATGGCGTCCACATTTATAAGTTTCCAAGAGCGAGGCGGCAACAGGAGCGTTGGATGCACAACCTCCGCATCCGCTATGATGAGCGTACACCGTGGAAATTCATGATCTGCAGCGTTCATTTCGAACCTCGCTGCATCAGCTTAAGGAAGCTGCAACCTTGGGCGGTCCCCACACTGGATCTGGGCGACAATGTGCCAGAGAATATCTTTTCGAACGAACAGTGCGAGGAGGATTTGGTGATCGATCGCAGCGAGCTAGAGAGCGACGCCGAGGATGAAGAAGGCTTACAGGAGGACGACGATGATCAAGACGAGGACGATCTGAAGCCGGATGTTGGAATAAAAAGGCGAAGACGTTTCAATAGAGATTCCTCCTGCCCTACCCAGACACCACCCTGGAAAGTCAAACAATGCTGCCTCCCCTATTGCCGTGCCTTCCGAGGCGATGGCATCAAGCTTTTTCGGCTACCGAGCAACCAAAACTCCATTAGCAACTGGGAACTGGCCACAGGAATGGTTTTCAAAGAATCACAACGGAATACGCGATTGATTTGCAGCCGTCACTTTGAGACAGAGCTGATTGGAGTGAGGCGTCTAATGCGTAACGCCATTCCCACAAAGCACTTAAATCCGCATAGCGTTGACCAGGTCCGTACTAAAAAGGAGAAGAGTCCTCAAGCCTCTATTATTCCCATCTGCTGCATGGCGGACTGCCACTACAATGGAAATGTGAAGCTGCACAAATTTCCCAGTgATCCCACACTGCTTAAACAGTGGTGCCAGGCTCTTCGGCTCACCGACACGCAGCGTTATTTTGGCAAGCACATTTGTTCGATGCACCTGCCGATGAACGACACACTGAGCTGTGTTATCTGCGGTGGAGATAACATAGAGTTGCCGTTGCTTGGGTTTCCGGAGAACCGCAACCAGCGCGCCAAATGGTGTTATAATCTCAAAATTGAGACAATACCAAAGTGGGACCACTCAAAGCACATATGCTGCCGGCACTTTGAGTCCTATTGCTTTGATAGGCCGGGTGAGCTACGTCCAGGAGCAGCTCCCACGCTCCATCTGAATCACAATGACACAAACATATTCTTCAGCGACTATGCCACTGGTCTTTCGTCCTCGCCAACACGCAATCAAATTAAAGACGAGCCGCTGGAATCGGAGTCTGACGAGATGCTGCTGGTGTAG
Protein Sequence: AKIKRSISDLKCCVHSCRRSRLEHGAQLFPFPTGKQQHLKWRHNLHLEPEEVNRSTRVCSAHFNRRCIEGKQLRSWAMPTQQLGHHDQPIYENPKNIPGFFTPTCALGHCRKRRSIDNDLRTYRYPRSEDLLEKWRVNLQLAPDQCRGRICANHFEPQVRGKLKLKTGAVPTLELGHDDGVIYDNEAIKTGMMEEEEGLTTEFQRLKPKNEMFEVVEEDVGENVGEEQHPDYQDENADEDDKDDQYFDPLELVETFEHRSNDDAQDDDEEEGRVLDSPSGYMVKKEIEQLPSSPPSPSPLPLRHQTLRQGKPANNVTPICCLKHCRKERTAFHLLSTFGFPKDRQLLLKWCANLHLNPDDCAGRVCIEHFQPEVLGTRKLKQNAVPTVNVGHDEPLRYSCHGVDQNLEDQDPQPQHSVFRLWSLKHCRKRKLTEPPDIALAKRKPLGMPIMKREWEMEKSKKMTQADNNKEVLSKWLHNTKIPYDPSRHRGYRICGLHFESEYLEADWPLQWVIPTLHLNQEDEIYLNSKPLQEDQLLMLAPLRIKTDLALLGSPSASASPSPRGRIRICCIPTCGQFGSNQVRLYRFPTEEQALLRWLVNTQQQPRLVDPKDLYVCQSHFEPEAICKKQLRNWAEPTLNLGHDGHVIPNAKHNGNISDSQDTEQAMKFIRERFCSVISCFQAGGPEEGEVRLYDYPEDMATTRKWAAACRHRSMQARSHGFKVCQFHFATECFDPDTGKLTEGSVPTLELTRDDMERQCLVAGCVKIDPNGARLRYYKIPKTAAQLEAWSNNLKIHPTVLMQGEQQYICEKHFEAFCFGANKGLRSGALPTLLLGHDDVDLLPNPESLFCQSKTDKCCVPGCGRIWQAGDPTMDELGKLKVCSAHFESSAIPTVELGHSSPDIYQADLPSLKSQKRSVKVYCCYPKCEEISLSKNLYYGLPQEKHLRSAWLRHMNIEDPKDGAVAELCPLHYVILYQHSAKNYPEYHDSNRLFLDDNYKDARNNRRVRIVSCVIKGCDMVKPRDGIPLHGMPQNQDILQMWIDNGQFEFLEQQRYMLKVCHNHFEPCCFFDDRRLLSWSVPTLHLPGEAFHQNPTAEQWQNMVKKQSAAKTNAVEKEESELYTDEDRTEPILKMEHIESEYEDKNSEMQALEVLLEVGHVERMESYEKVDKSPVIYTENAPFRSSPIRGQYNANQCAVEGCQVTVEDVDGTIKLHKFPASQEAAQKWKHNTQVDMDEKFWWRYRICSYHFDQECFQSARIRKGAMPTLLLGPQRPDKVYDNEFAQPEAEAEESFLEPPGIQLEEGCTSVSRVRKEVSSLCLPPRAPPRKSSKFCQIYSCTNHLTTENMTLHKFPHSEDMCLKWQHNTQVPFDPYYRWRYRICSAHFHPVCLVNMRLVHGSVPTLKLGPKAPSELFDNDFNAINLRLDKRLTESNANVYIKHEKREEGEGSPILLEPELQFQEDQDDRISAWNSKLQLRPIKLEKISYSQKKFGSDKCLLAHCQRQRFQHGVHIYKFPRARRQQERWMHNLRIRYDERTPWKFMICSVHFEPRCISLRKLQPWAVPTLDLGDNVPENIFSNEQCEEDLVIDRSELESDAEDEEGLQEDDDDQDEDDLKPDVGIKRRRRFNRDSSCPTQTPPWKVKQCCLPYCRAFRGDGIKLFRLPSNQNSISNWELATGMVFKESQRNTRLICSRHFETELIGVRRLMRNAIPTKHLNPHSVDQVRTKKEKSPQASIIPICCMADCHYNGNVKLHKFPSDPTLLKQWCQALRLTDTQRYFGKHICSMHLPMNDTLSCVICGGDNIELPLLGFPENRNQRAKWCYNLKIETIPKWDHSKHICCRHFESYCFDRPGELRPGAAPTLHLNHNDTNIFFSDYATGLSSSPTRNQIKDEPLESESDEMLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480199;
90% Identity: iTF_00480199;
80% Identity: -