Basic Information

Insect: Drosophila lacicola
Gene Symbol: -
Assembly: GCA_035045355.1
Location: JAWNPB010000133.1:7667708-7671877[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0035 0.23 12.1 0.6 2 23 254 276 253 276 0.94

2 9 0.015 0.99 10.1 4.6 2 23 418 440 418 440 0.91

3 9 0.0067 0.45 11.2 2.4 3 23 533 554 531 554 0.94

4 9 0.00036 0.024 15.2 0.7 2 23 790 812 789 812 0.96

5 9 0.0015 0.099 13.3 0.3 2 23 867 889 866 889 0.92

6 9 0.011 0.77 10.5 3.6 2 23 934 956 933 956 0.96

7 9 0.11 7.5 7.3 4.2 2 23 970 992 969 992 0.92

8 9 0.0043 0.29 11.8 0.3 3 23 1052 1073 1051 1073 0.96

9 9 0.051 3.5 8.4 0.6 1 23 1161 1183 1161 1183 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0035	0.23	12.1	0.6	2	23	254	276	253	276	0.94
2	9	0.015	0.99	10.1	4.6	2	23	418	440	418	440	0.91
3	9	0.0067	0.45	11.2	2.4	3	23	533	554	531	554	0.94
4	9	0.00036	0.024	15.2	0.7	2	23	790	812	789	812	0.96
5	9	0.0015	0.099	13.3	0.3	2	23	867	889	866	889	0.92
6	9	0.011	0.77	10.5	3.6	2	23	934	956	933	956	0.96
7	9	0.11	7.5	7.3	4.2	2	23	970	992	969	992	0.92
8	9	0.0043	0.29	11.8	0.3	3	23	1052	1073	1051	1073	0.96
9	9	0.051	3.5	8.4	0.6	1	23	1161	1183	1161	1183	0.99

Sequence Information

Coding Sequence: ATGGCCGCATCCATATATGCCACCCCACCGCCGGATCTGAGCAGCGAGGACACAGCGCTCTCCGATGTCTCCAACTCATCCACACTCAACAGAAAtcgcggcggcggcagcagcaacaacagcaccagcaacaacaacagcaacaacaacaacaacaacagtcacaCATTGCAGCCACATgaagccacagcagcaacagcagcaacagcagcgagcaCAACAGCCACAGAAATGTCACCCACTCAGCAAGCGCACTTGGACACGGAGTCCAAGTCGAAGTTGAGCGCCACGGGAAGCAACACAAATGAGGCAGACGAAGCTGATGGCGAGGAGGAGGGCGAGGGCGACGGCGAGGCAGACGGCGTTTTGGATCAAACGGCAATGGCCGCAATGGCCGCGGccgcagcaaatgcagcagccatgcagctgcagctgctggaggcGCTCAACGATGCGGCCAAAAAGCGACGCAAGCAACACAATCCCAGTCGTCTGGAGGCGCTCAATCTGAGCGGCGCCGAGACGGACGAGGGGGCCGCCAAAGATGCCGCAGCGGAGCCAGTGATCGACTACGAGGAGAAGCTGTCGAAAATGCTGCTGCCCAAGTCCATTGAGAAGCTGAAGGAGACattcgagctgctgcagcagcagaagctacAGCCCGAAGACATATCAGAAGCGGAGGAGAGGCAGCAactggaacagcagcagcagcgggagcgggagcgggagcaaTCGCCAATGAATCCCTATCAGACCTACTGCAAGCAGTGCGGCGAGAACTTTGAGACAGAGTTCAAGCTCAGCCTGCACATGCTGCAGGATcatcaacagcatcaacagcagcaacagttgtcgtcgcaacagcagcaacagttggcgGCAGATGAGCCCATGGACTTGCTGGCCAACATTCAAGTTAAACTGGAGCGTGCTGACAGTCCcacgcagctggagctgcagcagcagcagcagcaacagcagcagcagcagctggaactGGCCAATGGacatggcaacaacaataaggaGCACGAGCTCTGGCTGCAGGCCATGGcacagcagcaccagcagcaacaacagcagcagcagcagcagcagcagcatcaacagcagctgccggGCATGCCGCCCGCCTTTGCATTTCCGCCGGAGGCCGCAGCGCTGGGCTGGCCACTCTTGGGCATGCCCGGCTTTGGAGGCGTCGAGGGACTCAATCGGCCGCCGCTGCGCATCTTCAATCCGGAGGCCTATTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAATACTTTCTCAAGACGCACAAGGCCAACAAACATGGCATCTTTGATCCCGCCGGTGACTTGGCCACgcccaacaacaatatcagcaacatcaacaacaacaacaacaacaacaacaacaacaacaacagcagcaacagcaacaataacaacaacatcaacagcatcaacaatacgagcagcagcagcagctccacttCCATGTTccaacagctgcaaatgccgcgcgagccgccgccgccgccgctgccgccggcaGCACAAAAGCCACAAGAGCCACAATTGACGCCACCGGCGCCGCCGGCGGTGCACTGCGACATCTGCACGAAGCGCTTCACCAACGTCTTCGCCATGCGCCGGCATCGCGCCAAGCAGCACGAGCaggcagccacgcccacagcatCACCAACGCCCCAAGCGACGCGACGCGGCAGCCCCAACGAGCAGCCACAGCCTGCCCAGCCGCCAGCCCCAGTGCAGCAGGTCAAGCAGGAGCCCATGCCGGATGCCGAGCAGAAGCCCTATCAACTGCCCGAAGGCTTTCGCGAGGACTTCACgctggagcaggaggagcTGGCCtttgcgccgccgccgcgcaaGCTGCCggcccagctgcagcagcaggcgcgcGACGCCAGCTGTGCGCCGGAGAAGCTGCGGCGGCTGGGCGTCCAGCTGCCGGAGGCATTCTGTGAGCTGTGCTGCAAGGAGTACGCCAATCGTTACTTTCTGCGCACGCACAAATGGAAGCGTCATGGCGTCTTTGTGCCGCCCGAGGATCTGGGcaaggaggagcagcagccgctcatGCCCGCCGGCTGGCCATTCATGCCGCTCAATCTGATGCTGGCCAAGGCAGCCGCCGAGCAGGAACAGCAGCCCGACCAGGAGCAACAAGTCGacgacgagcagcagcagcagctgcagctggaggagcagccACACAAGCGCATCAAACTGGAGCCCTACGACGAGTCGACGCCGCCGGAAAAGCTGGACAGCTCGGCGATGGGTCTGCAGAATCTGCAGAAGCTGCAGTcgatgctgcagcagctcaacGATTTCAATGGCAAGCGACCGCTGCCGTGCCACCTGTGCGGCCGGGAGCTGGAGCATCAGTATGCGCTGCGTGCCCATCTCATGACCGAGCATgctggccagctgctgcccgAGGGCCATCCCATGCTctaccagcaacagcagcagccgcagcagccacagTTGCCGCTCAAGTTGTCGCCtttgggcggcggcggcggcggcggcggttcGCCCGGGGCTGCGGTCACGCCCACGTCGACGGCGAATGAGCTGCGCTGCCAGCAGTGCGAGCGCGAGTTTGCCACACAACAGGAATTCAAGCAACATATCGCCGAGGTGCATCTGGGCCGCATACCCGGCACCAGTCCGCTGCGCGAAGGCTTCTACACGCCGGAGCGTGCCACGGTGCCGGCTGCCGGCGGCGCTGCCGCTGTGCCGCCGCGTGCCGCCTACACCATAACGCCGACGTCCAGCTACTGCGAGATCTGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACGCACATGCAGCGCATGCACGGCATTGAGATCGAGAATGGCGCCCAGATCGGCGGCGTCGTCTGCAACATATGCAACAAGGAGCTGTGCAGCAAGTACTTTCTGCGCGTGCACAAGCACAACACGCACGGCATCATCGAGGATGGGGCACCACTGCCCCAGCCGCGTGGCAGCGCCCAGAACGGACTCAAGGCcgaggcacagcagcagcagcagcaacagcaacaacaacagcagcagctggttcTGGAGCCGGAGATCAATTTGACGCCGATTGGCGGCGACTCCGGCGCCGGCAACGAGCTGTGCCCGCTGTGCGCCCGCCAGTTCCGCAGCGCCAAGTGGCTGCGCACGCATCTGATGAACGAACACGGCGCCGCAGGCATCGAGAAGCTGCGCGACCTGGAACAGTCGCCACAGAGCGGCGCCGGCAGCAAGCCGAACAGTCCCACGCTCAAGATACCCAATGGCAATCCCGCTGGCGGCGTCGCCGGCGTCAGTCCGGCCAACAATCTGGCCCAGGCGCTGCAGAAtgcgcaacagcagctgttcgGCCAGATGCAGCTGCCCAAGGgaatgccgctgccgctgccgttgccgggCATGTTCGAGCAGACGCCACGCTTCAAGGAATACCAGTGCTCGCTCTGCCCCTTCACCACGCCCTACTATGCATTCCTCTTCATACACGAGCGCTCGCATGCGCTGCTCAACAATGGAGGCGACGGGGAGACGCATGTCGCCGCCGAGGCGGAGCCGCCGCGCAACGAACGGGACAGATCCTTTGCCTTGGTGCAGGGCAAGGCCAGGACCAAGCCGAGCCGCGAGCGAGCCGACCGAGCCGATGTGGAGCACATCGAGCCCACGAATCtgaccaccaacaacaacaacagcagcaacagcagcagcagccacagccacagcaatactaaggctgccacgcccacacccacGCCCACAACGATACACTCACCAGGCACAATTGCTGCCTCGCCGAAAGCGCGTTCCGCAACCGTGACACCGACGCCAGGACGACGCAGCACCATCAACTCCAAGCCCGGCACGCCCAACGGCATCAACGCCCAACGCTCGGCGGCCACCTCGCCGTTTGAGCCGTGCAGCGATCTGGCCAATGGCAGCGGCAAGCCGGCCAGCTATGCGCAGCCGGACAAGTCCGAGGAGGCATATCAGATGCAGGCCTTCCATTTGACGCCCGCCGACGGCGATGCGGAGGGTCTGTTTGCGCCCGCCCTTGTCTATTTGCCGGTGCGCGTGCGCGCCTCGGAGTCGACCACACTGAGCTTCAGGCTGACACCAGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNRNRGGGSSNNSTSNNNSNNNNNNSHTLQPHEATAATAATAASTTATEMSPTQQAHLDTESKSKLSATGSNTNEADEADGEEEGEGDGEADGVLDQTAMAAMAAAAANAAAMQLQLLEALNDAAKKRRKQHNPSRLEALNLSGAETDEGAAKDAAAEPVIDYEEKLSKMLLPKSIEKLKETFELLQQQKLQPEDISEAEERQQLEQQQQREREREQSPMNPYQTYCKQCGENFETEFKLSLHMLQDHQQHQQQQQLSSQQQQQLAADEPMDLLANIQVKLERADSPTQLELQQQQQQQQQQQLELANGHGNNNKEHELWLQAMAQQHQQQQQQQQQQQQHQQQLPGMPPAFAFPPEAAALGWPLLGMPGFGGVEGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPAGDLATPNNNISNINNNNNNNNNNNNSSNSNNNNNINSINNTSSSSSSTSMFQQLQMPREPPPPPLPPAAQKPQEPQLTPPAPPAVHCDICTKRFTNVFAMRRHRAKQHEQAATPTASPTPQATRRGSPNEQPQPAQPPAPVQQVKQEPMPDAEQKPYQLPEGFREDFTLEQEELAFAPPPRKLPAQLQQQARDASCAPEKLRRLGVQLPEAFCELCCKEYANRYFLRTHKWKRHGVFVPPEDLGKEEQQPLMPAGWPFMPLNLMLAKAAAEQEQQPDQEQQVDDEQQQQLQLEEQPHKRIKLEPYDESTPPEKLDSSAMGLQNLQKLQSMLQQLNDFNGKRPLPCHLCGRELEHQYALRAHLMTEHAGQLLPEGHPMLYQQQQQPQQPQLPLKLSPLGGGGGGGGSPGAAVTPTSTANELRCQQCEREFATQQEFKQHIAEVHLGRIPGTSPLREGFYTPERATVPAAGGAAAVPPRAAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEDGAPLPQPRGSAQNGLKAEAQQQQQQQQQQQQQLVLEPEINLTPIGGDSGAGNELCPLCARQFRSAKWLRTHLMNEHGAAGIEKLRDLEQSPQSGAGSKPNSPTLKIPNGNPAGGVAGVSPANNLAQALQNAQQQLFGQMQLPKGMPLPLPLPGMFEQTPRFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGDGETHVAAEAEPPRNERDRSFALVQGKARTKPSRERADRADVEHIEPTNLTTNNNNSSNSSSSHSHSNTKAATPTPTPTTIHSPGTIAASPKARSATVTPTPGRRSTINSKPGTPNGINAQRSAATSPFEPCSDLANGSGKPASYAQPDKSEEAYQMQAFHLTPADGDAEGLFAPALVYLPVRVRASESTTLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502799;
90% Identity: -
80% Identity: -