Basic Information

Insect: Drosophila lacicola
Gene Symbol: PRDM1
Assembly: GCA_035045355.1
Location: JAWNPB010000133.1:10593842-10598456[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.4e-05 0.0023 18.4 2.5 1 23 926 948 926 948 0.99

2 5 1e-05 0.0007 20.0 5.1 1 23 954 976 954 976 0.98

3 5 2.1e-06 0.00015 22.2 4.3 1 23 982 1004 982 1004 0.98

4 5 0.00071 0.048 14.2 2.4 1 23 1010 1032 1010 1032 0.97

5 5 0.00012 0.0082 16.7 0.1 1 22 1038 1059 1038 1059 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.4e-05	0.0023	18.4	2.5	1	23	926	948	926	948	0.99
2	5	1e-05	0.0007	20.0	5.1	1	23	954	976	954	976	0.98
3	5	2.1e-06	0.00015	22.2	4.3	1	23	982	1004	982	1004	0.98
4	5	0.00071	0.048	14.2	2.4	1	23	1010	1032	1010	1032	0.97
5	5	0.00012	0.0082	16.7	0.1	1	22	1038	1059	1038	1059	0.96

Sequence Information

Coding Sequence: atgcatggacatcatcatcatcaacagcagcagccgcagcagcagcagcagcagcaacagcagcagcagcaggcgctgccgccgccgcaacAAGTGCAACAAATGTCCGCCACAATGAAGCTGGCTGGCcatccacagcagcagcagcagcagcagcaacaacaaacacacatagccatacagcaacagcaacagcaacagcaacaacatccacatccgcatccacatccacatccgcatcatcatcatgcaCAGCATCCACATCATCATGCAAAGCTGCTGCGACGATcgcgcagtcgcagtcgcagtccaACGCCGGACGGCACACAGGATTACGATGTGACGCGCATGCGCGAGGAGGACTTTGAGCGTCTGGCCGTATATCTGGTGCCCGACGTACAGGCGGAGCGCGGCCTGCCCAACCGTGCGGATAAAACGCTGCCGCGCAGCCTGACGCTCAAGTCCTCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTCATACCGCGCGGCACACGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGCTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGATGATGACTATTATTATCTGGATGGCTCGGATCGTTCGCAATCGAATTGGATGCGCTACGTGGCCTCCGCGTACAGTTTGTCGGTCATGAATCTGGTTGCGTGCCAGCATCAGGAGAACATCTATTTCTATACCACCCGCGACATATTGCCCAACGAGGAGCTGATGGTCTGGTATTGCAAGGACTTTGCCAGCCGCTTGGGCTACGATGTGGATCCGGAGCGCACCATATTCGGTGCCTGCAAGCAGGACGTGGATgtcgaggaggaggaggatgaggatgaggagcTGGCGCACAAGAAACCCCATTATGCAATGGCCGCACCAGAAATACCCGCCGAGGTGGCTGTCAGTCACATTACCTATGTGATGGGTCTCCATTTGCCAGGTGcgccgccggcagcagctgctcctccgccaacagcaacaacaacagctgcccaATGCTGTCGACGCGCCAGTCCGCCTGCCCATGtcagcaccaccagcaacaacaacaacaacaacaacaacagcagcagcagcagcagcagcagctccaactcGCTGCATCCGCATATACATCACAGCCGGCACGCGTCCGTGATCATTGGGCAGGATCGTTCGCCgctgaacagcagcagctgcgacaaGGAGACGGCTGGATCGCCGCTGTGCGGCAAGGATGCGCACTATGAGCATCAGCTGACGCCGCAGGATGGCAGCGTGCGGTCGGTGCGCTCCGATGAGGGCTACCACAGCAACGAGTGCCAGGAGGATGGCCTGACGCCGCCGGAGGATTCCAGCGATAGCGAGAGCGAGCACAACTATGTGCTCGACTGCTCCAAGAAGGCGATTGCGCCCAAGGAGACGGTCATTGCGCAGGCGCAAAAGCCCAGCAGTGTGACGCCGccagccaccacgcccaccgTCGCTGCCGTCGCCGCCACGCCCAGCTGTGAGTCGGACAAGAACGAGTTTCGCAAATTCAAGGTGAAAATGCCGCTGAAGTACGAGTTCAAGAACAAGAGCTGTGTGAAAACGGAACCGCTCAAGGATGTCGATGAGCATCTGCCGCCAGCCGGTGTCAGcttggaggaggaggagctgcacGAGCTGCATgttgcagcagcggcggcggcggcggcggcagcggcagcggcggcagcgcatTCCGAGGACTCGCTATGCCCGCCCAGCACCACCACAACGCTGGGCGAggagcagcaccaccagcatcagcagcatctgGAGCCAACCAACACACAGCCCGCCTCCTCGACGGTAATTGTGCTGGAGCACAACTCGGGCGGCCAGACGCGCACCATTGTGCCGCTGAGCAAGCCCTACTATGAGGCCGATCCGCCTGGTGAGCGCTATGTGCGCTTCGCCCAGCCGAGCTCGAGCATACTGGAGACCATACTGACCAGCCAGCATCGCCTGgaggcagctgccgccgcagccAATGCCTGCAGGCAGGCGAACGCAGCGACGCCGCCGCCCACCTCGCCCACGGAGATGGCCTACAGCTACAAGAAGTCGCAGCGCTATGGCAATGCAGTTAGTCCCGATTCCAGCTCCAATCTGGGTCAGCCCCAAGAGCTGAGCGGCGCGCACGTTGTGAGCGAGCAGGAGCTCGGCTTGAGTCGCGCCACGCTGATCAAAGGCGAGTGCTCGCCGCCACCCGCCGCCTCCCATCATCATCACAATGTCATCTATTCGCCGTCGAGGACACATCATGCCGCCTACGAGCCGGGCAGCCATTCGCCCAGCTATGCCGGCTATGCGAGCTACCCGGGCGCGCAGTCCTTGCATGCGGCTACGTCCACGTTCCACTCACCGCCGCACAGCTCGCACTCGCCCTTCGATCGGCAGTCGAACGCGtccagcggcggcggctccgCCTCCAATTTGCATCTGCTGCAGAGCAGCACCCAAATGCTTAACCATCCGCTGATGCAGCCGCTGACGCCGCTGCAGCGTCTCTCGCCGCTGCGCATCTCGCCGCCCAGCAGCCTCAGTCCGGATGGCAATTCGTGCCCGCGCAGCGGCAGCCCCCTGAGCCCCAATTCGTTGGCCTCGCGCGGCTACCGCTCGCTGCCGTATCCGCTGAAGAAGAAGGATGGCAAAATGCATTACGAGTGCAATGTGTGCTGCAAGACCTTTGGCCAGCTGAGCAATCTCAAGGTGCATCTGCGCACCCATTCCGGGGAGCGGCCGTTCAAGTGCAATGTCTGCACGAAGAGCTTCACCCAGCTGGCGCATCTGCAGAAGCATCATCTGGTGCACACGGGCGAGAAGCCGCATCAGTGCGACATCTGCAAGAAGCGCTTCTCCAGCACATCCAATCTGAAGACCCATCTGCGGCTGCACAGCGGCCAGAAGCCGTACGCCTGCGATCTCTGCCCGCAGAAGTTTACGCAATTCGTCCATCTGAAGCTGCACAAGCGTCTCCATACCAATGATCGGCCCTATGTGTGCCAGGGCTGTGACAAGAAGTATATCAGCGCCTCCGGCCTGCGCACGCACTGGAAGACAACAAGCTGCAAGCCCAACAATCTGGAGGAGGAGCTGGccatggcggcggcggccaccTCCGAGTGCCTGGACAAGGATTTGCCGGAGCCGGACTCGCGCGAGGCCtatgagcagctgcagcagcatatGCATCCGGTGCATCCGAGCCTGCGTCATTTGGCCGGCGCCCAGTCGCCGCCGCGTCTCATTCCGCTGGGCGGCAATGGACAGCAGccgcacatgcacatgcagcagctgcagggcCACCAGCCGCATGCGCAGGCGAGCAATGCGCCGCCGGGCCACCTAATGCACTCGCCGCACGGCGGCCCGCCCATGCTGCTGACCACAGCCAatcagctgccgccgccaacaACGCCGCACcacatgcaacagcagcagcaacagcagcagcagcagccgccacagGCTTCGCCCGGCCGACAGCCGCCCacgcatcagcaacaacagcagcaacagcaacagcaacagcagcagcatctgggGCCACCGCATCATCTCGCACAGCACTCGCCCAAGTCGCTGAAGCCGCTGCCGGACGCTGGCTATCTGCACGGGCCGCTCGTGCAGACGCAGGAGAATCGACCCTCGGTCATCGAGTCCTCCAGCCAGCCCATGATCATTGAGTGCACGTAA
Protein Sequence: MHGHHHHQQQQPQQQQQQQQQQQQALPPPQQVQQMSATMKLAGHPQQQQQQQQQQTHIAIQQQQQQQQQHPHPHPHPHPHHHHAQHPHHHAKLLRRSRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVEEEEDEDEELAHKKPHYAMAAPEIPAEVAVSHITYVMGLHLPGAPPAAAAPPPTATTTAAQCCRRASPPAHVSTTSNNNNNNNNSSSSSSSSSNSLHPHIHHSRHASVIIGQDRSPLNSSSCDKETAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVTPPATTPTVAAVAATPSCESDKNEFRKFKVKMPLKYEFKNKSCVKTEPLKDVDEHLPPAGVSLEEEELHELHVAAAAAAAAAAAAAAAHSEDSLCPPSTTTTLGEEQHHQHQQHLEPTNTQPASSTVIVLEHNSGGQTRTIVPLSKPYYEADPPGERYVRFAQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQELSGAHVVSEQELGLSRATLIKGECSPPPAASHHHHNVIYSPSRTHHAAYEPGSHSPSYAGYASYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLQQHMHPVHPSLRHLAGAQSPPRLIPLGGNGQQPHMHMQQLQGHQPHAQASNAPPGHLMHSPHGGPPMLLTTANQLPPPTTPHHMQQQQQQQQQQPPQASPGRQPPTHQQQQQQQQQQQQQHLGPPHHLAQHSPKSLKPLPDAGYLHGPLVQTQENRPSVIESSSQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00476868;
80% Identity: -