Basic Information

Insect: Drosophila lacicola
Gene Symbol: RREB1
Assembly: GCA_035045355.1
Location: JAWNPB010000347.1:5750624-5752649[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3.3e-05 0.0022 18.4 0.3 1 23 446 468 446 468 0.99

2 6 0.007 0.47 11.1 0.7 2 23 481 502 480 502 0.96

3 6 1.6e-06 0.00011 22.6 0.7 1 23 508 530 508 530 0.99

4 6 2.6e-06 0.00018 21.9 6.3 1 23 536 559 536 559 0.97

5 6 0.0013 0.09 13.4 5.2 1 23 566 588 566 588 0.94

6 6 2e-05 0.0013 19.1 0.3 1 23 593 616 593 616 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3.3e-05	0.0022	18.4	0.3	1	23	446	468	446	468	0.99
2	6	0.007	0.47	11.1	0.7	2	23	481	502	480	502	0.96
3	6	1.6e-06	0.00011	22.6	0.7	1	23	508	530	508	530	0.99
4	6	2.6e-06	0.00018	21.9	6.3	1	23	536	559	536	559	0.97
5	6	0.0013	0.09	13.4	5.2	1	23	566	588	566	588	0.94
6	6	2e-05	0.0013	19.1	0.3	1	23	593	616	593	616	0.95

Sequence Information

Coding Sequence: ATGTCGGCCACGGATGAATTTTATCCAGATCTAGAGACGTGGTGTCGCCTGTGCCTAAGGGAGCTCAAGGATGCGCACACAATCTTTGCCGAGGACGACAAGGAGTTGTCGATACCGATGCGCTTGATGGCCTGCCTCTCGCTGGAGGCGAAGGCAACTGATGGCTTGCCGAAGAAGATTTGCGGCGATTGTCGATACCAGCTGGAGAAGTCGTTTCTTTTCCGCCAGCGAAGTCAAGCGGCTGATAAAAAGCTGCGGAAACATATTCGCCTTGTGAGCATGGGTAAAAAGAGCCGCGTCTTTGCCAAGTCGTTGGATAATGACTCCGATGAGGATGAGCTAGAATTCGTGGAATCCATGGAATTTATAGAAAAACTGGAGATGCTGCATGAAAAAAACTCACAAAAATGGCGGGAAAAGTACAAGGAAGAGattaaaaaagattttgagTGCCGCCTGGATACCGCGCGCACTGAGCTATGTGTGGAACTGCGCAAACAACTGATGGAGGAAGTGCGAAGTGATGTGCGTCAGCAACTACATGACGAAGTGCAAGAGGAAAGCCGCAGGGAACAGCTGGCAAAGCTTGTGGGTGAACTTGAAGTTTTCTTGGTTGAAAAGAAAGCCGGTCTCTGGGAGACTCTGGGTGAGCTGCCAGTTGACCCAAAGTTGAAAACCACATCCACCCCGGAGTCAACAACAGCACTAGCACCAACGCCTTTACCAGCGCCCAAGCCAACTATCGAGCAGCGTGTAACTCGGAAACGCGGTCGCATCTCGTCGCCCACAGTTCAGCCAAAGCGTCGACCAAAAGCCGCGGACTCTGAAGGTGCTGTATATACGATGGAGAGTGACTCCAAAGCAGAGACAGTATCCGCGGATGACGCGGAGATAGACACATCTGCGCCAGATACCATGGAGAGTTTTCGTGATATTAAAATGGTCGGCGCTGGCGACGTGGTGACGAGCCAAAATGGAGAAATCTATATCATAAATGCTGCCTCATCGGCAAACTCTACGCCAGGTTCCTCAATAGAATTTCAGCAGGAGAAGAACATCACATCGTACAATATTAAGGACAATGGAGAAATTCAGTTTACCGACTCCAAGTCTGAGGATATTGGTGATGTGATGGTGTTTAATCTTGATGATGAGGAAGGCGACGATCAGCAGGTGTATGAGTTTAACGACAATGTCATCATATTGTCAGAAGAAAAGGCAAACAGCCAAATAGTGACACCCGTCAAAGGTACAAAAAACGATTTTGTGGTGAAGCGAACTCCGCGCAGCAGCACCAAGTCGACGGTTGGACGTGCCAGCGATACGTTGAAAACGTTTCAGTGCCAGCTGTGCCCGATTGCGTTTGCTACTGAGAAAACGCTGTCGCGACATCTCAGCACGCACATCAAAACGCTGAAGAACGGAACCGGCGGGGCGCTCAAGTGTCCCGTTTGCCAACTGCAGCTATCCTGCGCCAGTTCGCTGAAGCGTCACATGATCATCCATACGGGGCTGAAGCCGTATAAATGCGATGAGTGCGAATTGTCGTTTTCGCAGCGCGAAGTCCTCAAGCGTCACATGGATACGCACACGGGTGCGAAACGCCACCAATGTCCACACTGTGACACCTGCTTTGCCCAAAAGACCAATCTGCAACAGCACATTAACCGCATGCATATGGAAGGTGAGCGTCAGCACAAGTGTCACCTCTGTAAGCGCAGTTTTAATCACGTGTCGGGTCTGAGCCGTCACCTTGTCGCCCACGCAGGCGTCACGTTTGCCTGCAAGGAGTGTGGACGTCAGTTTAACGACCGCAGCGCTGTGCAGCGACACGTGCAGAATGTGCACAAGGTCAAGGATACGGGTGCCGATTCAGCAACGGATAACAATGGAAATGATACGGAATTTGAATAA
Protein Sequence: MSATDEFYPDLETWCRLCLRELKDAHTIFAEDDKELSIPMRLMACLSLEAKATDGLPKKICGDCRYQLEKSFLFRQRSQAADKKLRKHIRLVSMGKKSRVFAKSLDNDSDEDELEFVESMEFIEKLEMLHEKNSQKWREKYKEEIKKDFECRLDTARTELCVELRKQLMEEVRSDVRQQLHDEVQEESRREQLAKLVGELEVFLVEKKAGLWETLGELPVDPKLKTTSTPESTTALAPTPLPAPKPTIEQRVTRKRGRISSPTVQPKRRPKAADSEGAVYTMESDSKAETVSADDAEIDTSAPDTMESFRDIKMVGAGDVVTSQNGEIYIINAASSANSTPGSSIEFQQEKNITSYNIKDNGEIQFTDSKSEDIGDVMVFNLDDEEGDDQQVYEFNDNVIILSEEKANSQIVTPVKGTKNDFVVKRTPRSSTKSTVGRASDTLKTFQCQLCPIAFATEKTLSRHLSTHIKTLKNGTGGALKCPVCQLQLSCASSLKRHMIIHTGLKPYKCDECELSFSQREVLKRHMDTHTGAKRHQCPHCDTCFAQKTNLQQHINRMHMEGERQHKCHLCKRSFNHVSGLSRHLVAHAGVTFACKECGRQFNDRSAVQRHVQNVHKVKDTGADSATDNNGNDTEFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00526814;
90% Identity: iTF_00491011; iTF_00551089; iTF_00506356; iTF_00563414; iTF_00475451; iTF_00617140; iTF_00534816; iTF_00526814;
80% Identity: -