Basic Information

Insect: Drosophila lacicola
Gene Symbol: Cf2
Assembly: GCA_035045355.1
Location: JAWNPB010000226.1:1266560-1271302[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.22 15 6.4 4.7 2 23 77 99 77 99 0.95

2 8 3 2e+02 2.8 0.4 1 23 131 154 131 154 0.89

3 8 0.42 29 5.5 0.2 1 10 180 189 180 195 0.85

4 8 2.7e-07 1.8e-05 25.0 0.8 1 23 396 418 396 418 0.98

5 8 5.1e-08 3.4e-06 27.3 2.7 1 23 431 453 431 453 0.99

6 8 4.6e-07 3.1e-05 24.3 1.1 1 23 459 481 459 481 0.98

7 8 5.1e-07 3.5e-05 24.1 3.5 1 23 487 509 487 509 0.98

8 8 1.7e-07 1.1e-05 25.7 1.4 1 23 515 538 515 538 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.22	15	6.4	4.7	2	23	77	99	77	99	0.95
2	8	3	2e+02	2.8	0.4	1	23	131	154	131	154	0.89
3	8	0.42	29	5.5	0.2	1	10	180	189	180	195	0.85
4	8	2.7e-07	1.8e-05	25.0	0.8	1	23	396	418	396	418	0.98
5	8	5.1e-08	3.4e-06	27.3	2.7	1	23	431	453	431	453	0.99
6	8	4.6e-07	3.1e-05	24.3	1.1	1	23	459	481	459	481	0.98
7	8	5.1e-07	3.5e-05	24.1	3.5	1	23	487	509	487	509	0.98
8	8	1.7e-07	1.1e-05	25.7	1.4	1	23	515	538	515	538	0.96

Sequence Information

Coding Sequence: ATGTTAAAGTctagcacaaacacacaggaatTGCGTCTGCCACGCCCCGAGGAGCACCAGCCACAGCCCACGCATCAAGTTGCCGCCGTGATAGCTTcatcagcagccgcagcagccgcagcagcagcagcagcagtaggagGAGCAGGATCCGGCCACAGCATGGACACGCTCAAGACAACGTTTCTGCCCAATCTCAGCATGGACCCGAACGTGATCAGTCCGCCGTACTGCCCCATGTGCCATCAGCAGTTCGAGCGCACACAGCACGCCGCCGAGCACATGCAGCTCTGCCATGGCATCACACTCAACGCACAGCCCGGCGGCATATCCAgtctcgagcagcagcagcagcaggcgcagcagcagcagcaactgaagCCGCTCAGTTTTGCGTGTTCCAACTGTGATGATAAGTTTGGTAGCCCGCTGGAGGTGGACGAGCACCATCGGCTGACGCATCAGACCGTCTTTTTGGCGCGCTGCATTGTTTGCAGCATTTATGGCGTCAATTCTGTAACACAGAATCCCAACGAATACAAATGCTCTCACTGTGGTGCCGTCTGCAATGCGGCCATGCTGGCCGCCGGTCAGCAAACGTTTATGGAGCATCAGGAGGCGCCGGTGACGCCGGACGATTTGCCAGCCATGGCGCCGCGTGATATGAGACTGACGCCCGAGgagcagcaacaccagcagcagcagcagcaacaacaacagcaacaacaacaacaacaacaacagcaacaacagcagcagcagcaacaacaacagcagctgcaacaggagcaacaattgcaacagcagcagcatcagcaggaGCATCATCACCAGCAACtcgaacaacagcagcagcagcagcagcaacaggagcagcagcgacaacgtGAACTCcaggagcaacagcatcaggATGACTTGAACGATCCGGCAACGCCCAAGGTGCCGCCGCTAACGGTAAAACTACTGAAGAACGGCAACGGCGCAACGGTAACACATCCCCAGGTCATCATCAAGGAGGAGCCACTCAGTTTGAGCGACAGCGGCGATGTGGTCAATGCGGTGCCTGTCTATGCCATACAAGCGAATCCTGGCGTCCAGCCGGCGGGCACACCTGGTGCCGGTGCGACCAGCGTTCTGGTTAGCACGCAATCGGTGCCCGCAGATTTGGCGCATAAGATCCGGCATAAATGTCCCGATTGCCCCAAAACGTTTAAGACGCCCGGCACGCTGGCCATGCACCGCAAAATACACACGGGCGAAGCAGACGCCACGCCCAAAGAACGCCCCTACACGTGCTCCTACTGCGGCAAGTCCTTCACTCAATCGAATACACTAAAACAGCACACTCGCATACATACAGGTGAGAAACCATTTAGATGTGGCTATTGTGGCAGGGCGTTCACTGTTAAGGATTACCTGAACAAACATTTAACGACTCACACGGGTGAAAAACCATTTCATTGTGGCTACTGTGAGAAGTCCTTCAGCGTGAAGGACTATCTCACGAAacacatacgcacgcacacCGGCGAAAAGCCGTACACCTGTCCGTACTGTGACAAACGATTCACGCAACGCAGCGCCTTAACCGTGCACACGACAAAGCTGCATCCGCTCTAG
Protein Sequence: MLKSSTNTQELRLPRPEEHQPQPTHQVAAVIASSAAAAAAAAAAAVGGAGSGHSMDTLKTTFLPNLSMDPNVISPPYCPMCHQQFERTQHAAEHMQLCHGITLNAQPGGISSLEQQQQQAQQQQQLKPLSFACSNCDDKFGSPLEVDEHHRLTHQTVFLARCIVCSIYGVNSVTQNPNEYKCSHCGAVCNAAMLAAGQQTFMEHQEAPVTPDDLPAMAPRDMRLTPEEQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQEQQLQQQQHQQEHHHQQLEQQQQQQQQQEQQRQRELQEQQHQDDLNDPATPKVPPLTVKLLKNGNGATVTHPQVIIKEEPLSLSDSGDVVNAVPVYAIQANPGVQPAGTPGAGATSVLVSTQSVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00540527;
90% Identity: iTF_00506305;
80% Identity: -