Basic Information

Insect: Drosophila lacicola
Gene Symbol: -
Assembly: GCA_035045355.1
Location: JAWNPB010000121.1:494851-496819[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.13 8.9 7.1 0.3 1 21 307 327 307 328 0.95

2 10 2.5e-06 0.00017 22.0 1.7 1 23 336 358 336 358 0.99

3 10 0.0074 0.5 11.0 0.6 1 23 361 384 361 384 0.93

4 10 1.4e-06 9.3e-05 22.8 0.8 2 23 391 412 390 412 0.98

5 10 1.4e-08 9.3e-07 29.1 0.6 1 23 418 440 418 440 0.98

6 10 3.3e-06 0.00023 21.6 2.0 1 23 446 468 446 468 0.99

7 10 0.00044 0.03 14.9 4.6 1 23 474 496 474 496 0.99

8 10 0.0011 0.074 13.7 0.3 1 23 502 524 502 524 0.98

9 10 8.2e-05 0.0056 17.2 3.6 1 23 530 552 530 552 0.99

10 10 0.00043 0.029 14.9 0.3 1 23 558 580 558 580 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.13	8.9	7.1	0.3	1	21	307	327	307	328	0.95
2	10	2.5e-06	0.00017	22.0	1.7	1	23	336	358	336	358	0.99
3	10	0.0074	0.5	11.0	0.6	1	23	361	384	361	384	0.93
4	10	1.4e-06	9.3e-05	22.8	0.8	2	23	391	412	390	412	0.98
5	10	1.4e-08	9.3e-07	29.1	0.6	1	23	418	440	418	440	0.98
6	10	3.3e-06	0.00023	21.6	2.0	1	23	446	468	446	468	0.99
7	10	0.00044	0.03	14.9	4.6	1	23	474	496	474	496	0.99
8	10	0.0011	0.074	13.7	0.3	1	23	502	524	502	524	0.98
9	10	8.2e-05	0.0056	17.2	3.6	1	23	530	552	530	552	0.99
10	10	0.00043	0.029	14.9	0.3	1	23	558	580	558	580	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATTTGTCGTACTTGCCTTAGCCTCTCGGGTCCATTTCTGTCCATTTACGATGGTGGCACTGGCAGCTGCTTGGTCGACATGCTGCGCGAATTCACAAGGACTAAGCCGCGGCGCGAGGATAATCTGCCAGCCAGGGTCTGCCTTAGTTGCATCAGCGAAATAAACCACTGCTATTCGTTTAAACTCAAATGTGAGAGCTCAAATCGAACGCTGCGACAGCTGCTGCCCAATGCGCTGCCCGAGGAGCCTGACCAGccatcaacagcagccaaatCCGCGGTGGCTACGTCCGAGAGCTCAGTGCAAACAAATGCGGTGTCAACAGCCACAGCGGAGGCACAAACGGATGCGGTGGCCACATCAGATGCCGCGCAAAACACCAGCATTGAGCAGCCAACGCTGCTGGCCAACGAGCCACTGATAGATGAGGCGGAGGGACAGGAGGAGGAAGAGTATGACTATGAATTTACCGAAGAGCAAGAAACAGATGAGACACCGTCCAAGGCGAGCGCCGAGAATATAATATTGCATGTGGAAAAAGACAACATTAAGTTTGAAACGGAAATGGTGTACAATAAAAACACAGGCGAGCTGCTTGAACAGGCGGTGGAAACAGTTGCCAAGCAGAAGGAGTATAAATATCGGCTTGTCAGCAATGGTAATGGCGACACATACATCTCACCAGAGCCAGCGCCAACGCTCGCGCTGCCCACGCGCAAGTGTGCCACAAAGCTGCCTAAGGCGGAGCAGCAATCGACGCATCAGGAGTCACAGTCAACGTCCAAGCGCAGTGTGCAGCATCAGCCGGCGGAGCAGCTGGATGTGCCGTCGCCTGCAAAAAAATCTAAACCCATTAACGCAAATGGCACGCCTGCGGGTGAATTGGATGAGTTGAAGGCGAAGTTCCACTGTGATCGCTGCAATGCAGGCTTTGCGCTGGAGAAATCCCTGATCATACATCGGCGGCAAAATAGCTGCACCCATCgcaatttcaaatgcaacaagTGTGAGAGGGTATTTGTCTCGCTGGATCATTTGACCGAGCATCAGGCAACGCATGGTGCGTTCATATGTCAGGAGTGCGGCTTGCGCTGCGAGTCCATGGAGCAGCTGGGCAGGCACATGGTGCAGACGCACAAGCGCAATTTACGCAATCAGTGCAATGTTTGCCAGAAGGTCTTTACCATGTTGTCCACGCTGCGGGATCACATGCGCATCCATACCGGTGAGAAGCCATTTGTGTGCAAAGTTTGCGGCAAGGGCTTCACACAAAATGCGAATCTACGCCAGCACATGATGCGCCATTCGGACATTAAGCGTTTCAAGTGCGAGCTGTGCAATCATTCGTTTGTGACCAAAGCGGAGCTGACCTCCCATGCGCGCACCCACACCGGTGTCAAGCCGTACCAATGTGAGGTCTGCTCCTCCAGATTCACCACCAGCTGCTCACTGGCCAAGCACAAGCGCAAGCACACAGGCGAGCGACCCTATGCCTGTGACTTGTGTCCCATGCGTTTCACAGCGCTCAACGTGCTGAAGAATCACCGACGCACTCACACAGGCGAAAGGCCCTACGTTTGTCCCTTCTGTTCGAAGAGCTTTACACAACGTGGCGACTGCCAGATGCATCAGCGAACGCATCAGGGCGACAAGATCTACATTTGCCCGGTGTGCAGCGAGGAGTTCAAAACGATGACTGATATGCGCACGCATCTGACGATGCACGAACAGGACGACAAACGATTGGTGCATTTCACCCTGTTGAGCAACAAGGAGAACGGGAATGCGGCGCTAGAGGAGGCGGACGAGGAGTCGGATGCAACCGATTTAATTTAG
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGTGSCLVDMLREFTRTKPRREDNLPARVCLSCISEINHCYSFKLKCESSNRTLRQLLPNALPEEPDQPSTAAKSAVATSESSVQTNAVSTATAEAQTDAVATSDAAQNTSIEQPTLLANEPLIDEAEGQEEEEYDYEFTEEQETDETPSKASAENIILHVEKDNIKFETEMVYNKNTGELLEQAVETVAKQKEYKYRLVSNGNGDTYISPEPAPTLALPTRKCATKLPKAEQQSTHQESQSTSKRSVQHQPAEQLDVPSPAKKSKPINANGTPAGELDELKAKFHCDRCNAGFALEKSLIIHRRQNSCTHRNFKCNKCERVFVSLDHLTEHQATHGAFICQECGLRCESMEQLGRHMVQTHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCKVCGKGFTQNANLRQHMMRHSDIKRFKCELCNHSFVTKAELTSHARTHTGVKPYQCEVCSSRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKTMTDMRTHLTMHEQDDKRLVHFTLLSNKENGNAALEEADEESDATDLI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551023;
90% Identity: iTF_00551023;
80% Identity: -