Basic Information

Insect: Drosophila lacicola
Gene Symbol: ham
Assembly: GCA_035045355.1
Location: JAWNPB010000269.1:82698-107539[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.55 37 5.2 0.0 2 21 229 248 228 251 0.87

2 9 0.068 4.6 8.0 0.2 3 23 260 281 258 281 0.91

3 9 1.7e-07 1.2e-05 25.6 1.7 1 23 287 310 287 310 0.96

4 9 3.3e-07 2.2e-05 24.7 1.5 1 23 316 338 316 338 0.97

5 9 8.3e-05 0.0056 17.2 3.8 1 23 344 366 344 366 0.97

6 9 0.0018 0.12 13.0 2.0 2 21 374 393 373 394 0.94

7 9 1.3e-09 9e-08 32.3 1.2 1 23 878 900 878 900 0.99

8 9 3.4e-07 2.3e-05 24.7 0.9 1 23 906 929 906 929 0.97

9 9 4.3e-05 0.0029 18.1 6.8 1 23 935 957 935 957 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.55	37	5.2	0.0	2	21	229	248	228	251	0.87
2	9	0.068	4.6	8.0	0.2	3	23	260	281	258	281	0.91
3	9	1.7e-07	1.2e-05	25.6	1.7	1	23	287	310	287	310	0.96
4	9	3.3e-07	2.2e-05	24.7	1.5	1	23	316	338	316	338	0.97
5	9	8.3e-05	0.0056	17.2	3.8	1	23	344	366	344	366	0.97
6	9	0.0018	0.12	13.0	2.0	2	21	374	393	373	394	0.94
7	9	1.3e-09	9e-08	32.3	1.2	1	23	878	900	878	900	0.99
8	9	3.4e-07	2.3e-05	24.7	0.9	1	23	906	929	906	929	0.97
9	9	4.3e-05	0.0029	18.1	6.8	1	23	935	957	935	957	0.98

Sequence Information

Coding Sequence: ATGGAGCACTTGTTCAATGACAAGGCGCAGCAGTTCCTGCTGGAAATGGCGCGCCTGCGCGAACCCGTCTGTGATCTGGATATCCGTGATACTGGCGTCTATGCCAAGACACATCTGCCCCGCGGCACCCGCTACGGACCCTTCCCCATGCGCCTCTGCCAGCAGCCCAGCGATCGCCATCTGGCCTGGGAGGTAATCGCCGGCCCGCTGTTCCATGGCTGGCTGGAGCCTTCGGCGGATGTGGCCACATGGCTGAAAAAAATACGCGCCGCGCCGAGCGCCGAAATCGAAGAGGCTAATTTAAGGAATTTCATAACCGCCGGCTATCTGTGGTACGAGACGAAGCGCGACGTGAATGCTGGCGCGGAAATTGTCGTCGATGCCAGGTCCAAAACCCCCTACGACATCAGCGACAGCTTCATGAACGGCAGCGctgcgggcagcagcagcagcggcgcagcagccgcagcggcggcggcagcggcagcggcagcagcagccatggcagcggcaacaaacagcagccaaaacaacaacagtaacaacaacaacaactgcgatgATCGCAGCGATCGTGATAACGGCTTTTACAGCGGCGACGAATTTTCGAAGGAGAAGAAAAACTCATCGTTAAATAGTCAGGGCGACAACGATTTCACAGACGACGAAAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGACCTAGAACGcctGGACGATCATCTGGTTGGCGCGCATCATTTCAAGCGCGGCGAATTCGGCTGCGAGCTCTGTGCCCAACGCTTCTCCCATCGCCCTTTGCTGATCAAACACGGCGCGATCGCCCATAATAATATCAGGAAATATTCCTGCGAGAATTGTTCCAAGGTATTCTGCGACCCATCGAATCTACAGCGTCATATTCGGGCCTATCACGTCGGCGCTCGCAGTCATCCGTGTCCGGAGTGCGGCAAAACGTTTGCCACCTCGTCCGGGCTGAAGCAGCATCAGCATATCCATTCGTCGGTGAAGCCGTTCGCGTGCGAGGTCTGCTTCAAGGCGTACACACAATTCTCGAATCTGTGCCGGCACAAGCGCATGCACGCCGACTGCCGCATGCAGATCAAGTGCAAGAAGTGCAACACTAGCTTCAGCACGGTCACCTCCCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCGCACAGCTTTCCCAGCCAGCCAAACAGTCGACtccatcaccagcagcagcagcagatcggGACGCAGCATCATCAgtcggcgccgccgccgccgccgttgctttTGCCGCCAGGTGCTCATCAGCGactcgccgctgccgccgccgccgccgcggcctctgccagcagcagcgaaccGGGCAGCTCTGGGGCAGCCATGGCCACGCCACCGAATCATCATCATATATTCATGATGCGTCCGACGCCGTCGTTCTTTCCGGGCTTCCCGCACTACGGCTTGCCCAATTTCTTTACGCCcggactgcagcagcagcagcagcagacaacgGGCAGCTTCCAGCTGCCGCACATGTTCTCCGCCGGCGTGGACATGGGTCGCGGCCTGGCGCCGCTTGTCTCCCCAAATGCGACGAccttccagcagcagctgcaggcggcCATGAGCCTCAAGTCGGAGGCGGAGGCGCCGTGCCTGAAGCGCGCGTCCAGCACGCCGGAGCGCAAGCCCATCAAGGCCGAGCTCCAGGCATCCGATGAGGAGCCGGAGCAGGAGCCGGAGCAGGAGCCGGAGGAGCAGCTGGACTATAATTGCAAGCGCGTCAAGCGGGAGAGCAGCTGCTCGCAgcccgcagcagcagaagatgAGCAGGAGGACATTGACAATGACAGGAAATCGATAGACATAATCAGCACGCCGCCGCCCGCGGAAACGGAGCTGGAGCGGAATCGGGAGCCGCAGCCGGAGCTGGACAAGAGCGGCGCCGCGGAGCTGCCGCTCGACTTGTCCATCAGTCGCAAGCGACGCAGCTCGCCCGTGCCGCTCGCCATATCCCTGTCCAGCCGCACGCCCACGCCCGAAATGGAGGAGCCGGAGGAGGAGCCGGAGACGGAGGAGCCGGAGGAGAggctgccgccgccggccaAGCAGCTGAAGCACAGCTCCGGCGAATCGTCCACGTCACGGCAATCCTACAAgggcagctgccgcagcacgCCCAGCGTGAGCGCCTCGCCGGGACCCACGCCCTCCCCCTCGCCGCCCATCAGCAGCAATGGCGGCAGCAACGAgagcgccgctgccgccgctgctggcgccgccgctgctgcgggcgctgctgctgctgctgctgccgcagcggcGGCAATGGCCTGTCCGAGGCAGCTGCatccgcagctgctgctggaggagtTCTATCGGACGACCTTCAACCAGCAACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGTCGAAGACgccagctgcggctgccagcatcagcagcagcagcagcagcagctcgcgtCATCTGCCGTTTCCGCCCGAGCACAATTTCCACGAGGCGCTGCGTGCCGCCGGcctggccgccgccgccgcccgacCGACAGTCGCCGCCGCCAATAACGGGGGCAAGCTAAAGGATCGCTACACGTGCAAGTACTGCGGCAAGGTGTTTCCGCGCTCCGCCAATCTGACGCGGCATCTGCGCACGCACACCGGCGAACAGCCGTACACGTGCAAGTACTGCGATCGGGCGTTCAGCATCTCGTCGAATCTGCAGCGGCACGTCCGGAACATACACAATAAGGAGCGACCGTTTCGCTGTCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTGAAGAAGCACGAGGCGGACGCTGGCGGCTTCGAGTTTAACGATTCGCCCAGCTCGAACGAGGCCAACGATCGGGACGAGGCCTGCTTCGACGACATACGCTCCTTCATGAAGGGCGTCTACACGCCCAACAGCCTCCACGGCGCCGATGGCGACACCGAGGAATATGCCGGCAGCGACGACCAGTTGTCCGTCTCCACGCGCCAGTCCGTCAGCTTCGacaaggagctgctgctgctgcccaacaacaacaacaacaacaacaacagcagcaacatcaacaacaacaacaacaacagcaacagcagcagcaacaacaacaatcagacaACTCTGAGCGAATCCATCGCCGTGAGCACCTAG
Protein Sequence: MEHLFNDKAQQFLLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPSADVATWLKKIRAAPSAEIEEANLRNFITAGYLWYETKRDVNAGAEIVVDARSKTPYDISDSFMNGSAAGSSSSGAAAAAAAAAAAAAAAMAAATNSSQNNNSNNNNNCDDRSDRDNGFYSGDEFSKEKKNSSLNSQGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFGCELCAQRFSHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDSSHSFPSQPNSRLHHQQQQQIGTQHHQSAPPPPPLLLPPGAHQRLAAAAAAAAASASSSEPGSSGAAMATPPNHHHIFMMRPTPSFFPGFPHYGLPNFFTPGLQQQQQQTTGSFQLPHMFSAGVDMGRGLAPLVSPNATTFQQQLQAAMSLKSEAEAPCLKRASSTPERKPIKAELQASDEEPEQEPEQEPEEQLDYNCKRVKRESSCSQPAAAEDEQEDIDNDRKSIDIISTPPPAETELERNREPQPELDKSGAAELPLDLSISRKRRSSPVPLAISLSSRTPTPEMEEPEEEPETEEPEERLPPPAKQLKHSSGESSTSRQSYKGSCRSTPSVSASPGPTPSPSPPISSNGGSNESAAAAAAGAAAAAGAAAAAAAAAAAMACPRQLHPQLLLEEFYRTTFNQQPFHFLGQMGGRPGFESKTPAAAASISSSSSSSSRHLPFPPEHNFHEALRAAGLAAAAARPTVAAANNGGKLKDRYTCKYCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEFNDSPSSNEANDRDEACFDDIRSFMKGVYTPNSLHGADGDTEEYAGSDDQLSVSTRQSVSFDKELLLLPNNNNNNNNSSNINNNNNNSNSSSNNNNQTTLSESIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00526726;
90% Identity: -
80% Identity: -