Dlac015099.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacicola
Gene Symbol
su(Hw)
Assembly
GCA_035045355.1
Location
JAWNPB010000347.1:3638177-3642322[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0007 0.047 14.3 2.2 1 20 231 250 231 252 0.94
2 12 2.9e-06 0.0002 21.7 0.4 3 23 303 324 301 324 0.93
3 12 0.11 7.2 7.4 0.1 1 23 330 352 330 352 0.96
4 12 7.9e-07 5.4e-05 23.5 2.5 1 21 359 379 359 380 0.95
5 12 3.4e-06 0.00023 21.5 0.6 2 23 392 413 391 413 0.96
6 12 0.00011 0.0074 16.8 5.3 1 23 424 446 424 446 0.99
7 12 8.5e-05 0.0058 17.1 0.9 1 23 452 474 452 474 0.97
8 12 1.7e-05 0.0012 19.3 0.8 1 23 480 502 480 502 0.99
9 12 1.6e-06 0.00011 22.6 3.0 1 23 508 530 508 530 0.98
10 12 0.0045 0.31 11.7 0.9 1 23 534 556 534 556 0.96
11 12 0.00011 0.0073 16.8 0.2 1 20 564 583 564 588 0.92
12 12 3.8e-05 0.0026 18.3 0.3 3 23 608 629 606 629 0.96

Sequence Information

Coding Sequence
ATGCCTGGTCACATTAATATTCTCTCGAGGCATTCAATGAGCGCCAGCAAGGTCGCCCCAGCGGCAACTCCCGCCtccagcagcatcaacattTCGGACGGAGAGAAACCCAAGGAAAAACGCACTGGCACACGCATGAAGCTGCTCAACGATGTGGCAGCAAAGGCTGCAGCTGCCAGTAAGGGCGCCTCCGTGTCGCCGCGCCTCAAGCCGGAGAAACGCACAAGCATCAAAatactcaacaacaacaacaacgatgaaGCTCAGAGTAGTACAAAGGGCGGTGATAGGCGTGCCACGCCCAAAACCGCCAGCACCAGCGTCAAGATATTAAACGAGAAGCGCTCGGCGCCCGCCAGCACAGCCGTGGAAACGGCCAAGATAAAGACATCGcccagcaagaagaagaaaatggATCACTATGTGCTGCAGGCCATCAAAAGTGAGAACAACAAAGCGGAGAACACGACCAGCGTGGTGGTGGTCGAGGACGAGGACACCATAGACTTTATACTGGCCGATGATGATGTCGAGCTGGGTGCCGGAGCAAAGGAGAATGGCGAAGAATTTGTGGTATCTGGCGTGgatgaagatgatgatgacgacgacgacgatgacgaggaTGACGGTGTGGTGGAAGGCGGTGCTAAGCGCAGAAGTGGCAACAACGAACTCAAGGAAATGGTCGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGACGCGTCAAAAGCTTAAAGAAACACTTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAGGCGGACATGCTCAAGAATCTGGAGAAGATCGAGAAGGATGCTGTGGTCATGGAAAAGAAGGACATATGCTTCTGCTGCAGCGAGAGCTACGACACCTTTCATCTGGGCCACATCAACTGCCCCGACTGCCCGAAGTCGTTCAAGACACAGACCAGCTATGAGCGTCACATTTTCATAACACACTCGGAGTTCAATGATTATCCCTGCTCCATTTGCAATGCCAAGCTGAGGAGCGGCGCGCTGCTAAAGCTgcacgagcagcagcatcaattGCGCGGCAAGCCGTTTGCCTGCAAAATCTGTGGCAAGGACTTTACGCGCTCGTATCACTTGAAGCGCCATCAGAAATACTCGTCCTGCTCGGCCAATGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCCTCGACAATTTGCGCGCTCATCTCAAACAGCATCTGGGCACCCAGGTGGTCAAGAAGCCGGAGTACATGTGTCACGTGTGCAAGAATTGCTTCTACAGCCTCTCCACACTCAACATTCACATACGCACCCACACGGGCGAAAAGCCCTTCGATTGTGATCTGTGCGACAAAAAGTTTTCGGCTCTGGTGGCGCTCAAGAAGCATCGGCGTTATCATACGGGCGAGAAACCCTACACCTGCACTGTGTGTAGCCAATCTTTTGCCGTCAAGGAGGTGCTTAATCGCCACATGAAGCGGCACACTGGCGAGCGTCCCCACAAATGCAACGAGTGTGGCAAGAGCTTTATCCAGGCGACACAGCTGCGCACCCATTCCAAGACGCATCTGCGTCCCTACGCGTGCTCCATGTGTATCCAAAAATTCAAGACGGAGAAGCAACTCGAGCGCCACGTTAAGGATCATACGCGTCAGAAACGCGCCTCCTTTGCCTGCACGGAGTGCACAAGAAGTTTCCGCACCAGCGCGCTGCTCAAGGAGCACCTGGACGCTGGCGATCATTCGCCTGTTAAATCGACACGAGCCAAGCGCTCGGCCAAAATGATCGAGCGCACGGACTGCGCCATTTGCGACAAGAACTTCGACACGACCGAGACACTCCGGAATCATATACGCAGCGTGCACGAGTGCGACCCGGATGACATCTTTGGCACGGAGCCACCAGCCAAGCGCAGAGCTAAGAAGGCCGTCGTGGCgccggtggcggcggcggcggagcaGAAAGAGCAGGAGGAAGACTTGCCGGCCGCCAACACGTCAGCCGGCTCGCTCATCTCCAGCAAAACGGATGGCAACGGAGTCGTGGTGCGCGAGTTTCTGGTGGATGAGGGTGACGGCAACGCGCAGACGATTGTTCTGGAAAACGAGGTCTACACCATTTTGCCACTGGAGGGTGACAAGGCAACCGAGCCGACGGCCGAGACCGATGTCAAGGCCGAGTCGTCCAAGGAGAAGCCATCTGTGTCGCCGGTGGTCAAGAAGGAGCAACGAAAATCACTGGCCGCCAGCTTGGCCGCTGCCATTGCCGATAATCTGGAGGAGCCGTCAAGCGATGATGAGTTCGGTGGCGAGGTGCTAACCGAGGAGGATCTGAAGCTCAAGGAGAACATTGCCAAGCTAATAGACATGCTGGTCGATCCGCAAACCCTCAAGAAATACGGCTGGCCCAACAGCTCCGAGGAGTCGGTGCTGTGCAAGGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGGCAGCGAAGCCTATGCCGAGTTGGACTACGGCAGTCGCATGCGCGAATATTGCAAGCTGCTTTTCACCGTGGTGATTCACAACGATTCGATCAAGGCGCTGCTCAACAATTTTCCCATCGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATCAGGACCAGGATCAAGAGGCAGACAAGGGCAAAGACAAGGAGTCCGAgaacacggacacggacaccaGAGAGGATGCTGTTGAGTCCGAGGCTTAA
Protein Sequence
MPGHINILSRHSMSASKVAPAATPASSSINISDGEKPKEKRTGTRMKLLNDVAAKAAAASKGASVSPRLKPEKRTSIKILNNNNNDEAQSSTKGGDRRATPKTASTSVKILNEKRSAPASTAVETAKIKTSPSKKKKMDHYVLQAIKSENNKAENTTSVVVVEDEDTIDFILADDDVELGAGAKENGEEFVVSGVDEDDDDDDDDDEDDGVVEGGAKRRSGNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSGALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYACSMCIQKFKTEKQLERHVKDHTRQKRASFACTECTRSFRTSALLKEHLDAGDHSPVKSTRAKRSAKMIERTDCAICDKNFDTTETLRNHIRSVHECDPDDIFGTEPPAKRRAKKAVVAPVAAAAEQKEQEEDLPAANTSAGSLISSKTDGNGVVVREFLVDEGDGNAQTIVLENEVYTILPLEGDKATEPTAETDVKAESSKEKPSVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDEFGGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQDQEADKGKDKESENTDTDTREDAVESEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00495995;
90% Identity
iTF_00506253;
80% Identity
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