Basic Information

Insect: Drosophila lacertosa
Gene Symbol: -
Assembly: GCA_004143845.1
Location: SCDZ01000149.1:53948-56233[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.3e-05 0.0024 18.4 2.5 1 23 429 451 429 451 0.97

2 7 1.8e-05 0.0019 18.8 0.2 1 23 457 480 457 480 0.97

3 7 0.021 2.2 9.1 1.9 1 23 486 509 486 509 0.92

4 7 1.9e-05 0.0019 18.7 2.8 1 23 548 570 548 570 0.95

5 7 0.0003 0.031 14.9 1.4 1 23 576 598 576 598 0.97

6 7 0.00013 0.014 16.1 0.4 1 23 604 626 604 626 0.98

7 7 0.0018 0.19 12.5 3.1 1 22 632 653 632 656 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.3e-05	0.0024	18.4	2.5	1	23	429	451	429	451	0.97
2	7	1.8e-05	0.0019	18.8	0.2	1	23	457	480	457	480	0.97
3	7	0.021	2.2	9.1	1.9	1	23	486	509	486	509	0.92
4	7	1.9e-05	0.0019	18.7	2.8	1	23	548	570	548	570	0.95
5	7	0.0003	0.031	14.9	1.4	1	23	576	598	576	598	0.97
6	7	0.00013	0.014	16.1	0.4	1	23	604	626	604	626	0.98
7	7	0.0018	0.19	12.5	3.1	1	22	632	653	632	656	0.91

Sequence Information

Coding Sequence: atgaagtGTGCAGTGCAAAGCTGCGCGAACAAATTTAAGTCGCGACAAAAACATTCACAACAATTGAGTTTCTTTAGTTTTCCGAAAAATCCAGAGATTTTGAAAAAATGGATTTCATTTTGCCGCAAAAGTAACAAAGAGAAACTAAAGGCGCCCCTAAAAAGCGTCATTTGCAATGAACACTTTAAAGAGGAAGATATCCAAGGAAGACTGCAATTTCAAATGGGCTTGTGCTCAAAGCGAACACTCAGACCGGGCGCCGTACCATGCATCAATAAGAACGATGTAAGTGCGGTCGAGCGAGAGCGATCGGAGAAGCGAAAGAACAAGAAGTTGGTCGCTGAGCTGCTTGAGGAAGCTGCCGCACGTGAGGCAGCCGAAGCTAGCGGAGCAATTGTTATAGCACCGGACTTTATCAGGAACACAGGCATTGTTTCTGTACCTGACTTTGTTAGTGCCACCGGAAATGCCTTCATTCCGTTCACACCGACGCCCAGTGAAAGTGATCCCCTAGCCGAGGAACAGGCGGAGTTGGACGAGTGCCCAAAGAACAGTAGCCGAGAAGAAAGTTTTATCGAACAGCATAAGTGTCGCACCTGCCACACACTTTTTGTGGTTGATGAAAACGCTAAGGATCTGAACGACGGGCAAAACGCTGTGATGTTATATCACATCGAAGTAATTACCGGCATTTGGATCCAGTGCAAAGAAGGAATGTCACCGTTCATGTGTTCAAGCTGCGTCGGTAATCTCCGCACAGCCATCGAATTTCGAGAGACGTGCATACAAACCGAATTGCACCTGGCGGGTGGTGACGCTGACTTCATTCCAACTGTAATCAAAGATAACGATGTTGAGCCTTGGAGTTCACATGATGTCAATGATACACGAGAAGaccaggagctgctgcagataAGTGATGAAATCGTTAAGGAAGAGTTTGTTTCTGTATTTCCTGCAGACGATCAACATGGTCAGACAATGGTAGTTGAGCCTTTGTCACTGGCAACATCAACACAAGAAATGATTCGGACAATAAATACATCCGGTGCAGATCCCAAAAGTATTGCATTGGGAGCGCAAATTTATGAGGACCTTTTAAACGAATACAGGGGAAAGGACAAGATACCACGACCAAGACAGCGAAAGACTACAAATTCAAGAATTAAATCGGCAAGGCAAAGAAAACGTAAGCCTAGAGATCCAAAACCGAAGCGACCCAAACGAACGAAAGAGGAAAGAAATCGGATACGTCGCGAGCAGATCAGAGCCATGCCGCTGAATCATGTTTGCGATCAGTGCGGCGCCTCATTTCGTGTTCGATGTAATTTAACAATACATATGTTGCGTCATACGCGCACCAAAAACTATCCTTGTCCCGAGTGCCCGAAGAAGTTCTATGATGCCTATATGCGAAATATTCACATACGTGTGCGGCACAGAGGCGAACTCCCGTTTGCCTGCAATTATTGCAGAAAATCATTTGGTTCGTCGAACACTCGATATCTGCACGAAAAAAAGGTTCATGGAGCATCTCCGCGCATTCACAGGAACGCGAATCGCTTAAACAAACGGATTGAGCTTAAGgatgaccagcagcagcagtcacagGAAGACCAGGACCAAAAGTCAAACGTTCGTCATTTTTGCACATATTGCGATAAGAGCTATGCAACAAAATACGCACTCAATTGGCATACCAATCAGCACATCGGTGTTAGGCCTTTCAAATGCAAGCTCTGTGATACGAGCTTTGCAGATCCCCAGTCGAAAAAGAAGCACGAAATGCAGCACGACAGTAAACGTCCCTTTGAGTGTGATATCTGCCTTAAGGGCTTCTACGTGCGCAGCAAGCTGAAGGAACACGAACGAATTCACACCGGCGAACGTCCTTATAGGTGTGATGTTTGCAACGCATTCTTCCGCTACAAGTTCAACTTATACTCGCATCAATTTAGTAAAATGCACAAGGAGAATCTGCAGAAACCAACAAAGGTTGAAATTATCGACGATTCAAATGAATAG
Protein Sequence: MKCAVQSCANKFKSRQKHSQQLSFFSFPKNPEILKKWISFCRKSNKEKLKAPLKSVICNEHFKEEDIQGRLQFQMGLCSKRTLRPGAVPCINKNDVSAVERERSEKRKNKKLVAELLEEAAAREAAEASGAIVIAPDFIRNTGIVSVPDFVSATGNAFIPFTPTPSESDPLAEEQAELDECPKNSSREESFIEQHKCRTCHTLFVVDENAKDLNDGQNAVMLYHIEVITGIWIQCKEGMSPFMCSSCVGNLRTAIEFRETCIQTELHLAGGDADFIPTVIKDNDVEPWSSHDVNDTREDQELLQISDEIVKEEFVSVFPADDQHGQTMVVEPLSLATSTQEMIRTINTSGADPKSIALGAQIYEDLLNEYRGKDKIPRPRQRKTTNSRIKSARQRKRKPRDPKPKRPKRTKEERNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYPCPECPKKFYDAYMRNIHIRVRHRGELPFACNYCRKSFGSSNTRYLHEKKVHGASPRIHRNANRLNKRIELKDDQQQQSQEDQDQKSNVRHFCTYCDKSYATKYALNWHTNQHIGVRPFKCKLCDTSFADPQSKKKHEMQHDSKRPFECDICLKGFYVRSKLKEHERIHTGERPYRCDVCNAFFRYKFNLYSHQFSKMHKENLQKPTKVEIIDDSNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506143;
90% Identity: iTF_00530299;
80% Identity: iTF_00530299;