Dlac012625.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacertosa
Gene Symbol
-
Assembly
GCA_004143845.1
Location
SCDZ01000132.1:142682-147738[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 8.6 9e+02 0.9 0.0 5 11 201 207 199 210 0.88
2 9 1.4 1.5e+02 3.4 0.1 1 13 370 382 370 390 0.81
3 9 0.00018 0.018 15.7 0.9 3 23 748 769 746 769 0.96
4 9 0.00069 0.072 13.8 3.4 1 23 797 819 797 819 0.97
5 9 1.3e-05 0.0013 19.3 2.8 1 23 825 847 825 847 0.96
6 9 3e-05 0.0032 18.1 0.9 1 23 853 875 853 875 0.98
7 9 0.0018 0.19 12.5 1.4 1 23 881 903 881 903 0.97
8 9 0.009 0.94 10.3 0.0 2 23 910 931 909 931 0.96
9 9 0.0037 0.39 11.5 0.1 3 21 939 957 937 958 0.94

Sequence Information

Coding Sequence
ATGACGCCAGCAGCTtgggcagctgttgctgccactgggGCAGCCGTTGGGGCAGCCGCCGGTACGGCCACTGTCGGTGCGGCCATCGAGGCAACAGCTGGACCCGTCGAGGAGCCGCGCCAGCGCTGCGGCACCGTCTACACCTGGAACTGTGCGGGCGAGCTGTACGGCATCGAGTGCGAGCTGTGCGAGGAGCGACCCCTTTGCGCCCTCGACGAGTTCGCGGAGCATATGGAGCTGTGGCATGCCGACTGGCAGCAGGCGCCCGTCGACGAGCTCATGCTGGAGGTCTTGGCCGAACAGTCCAGTGGCGGCGAGGTCAACGAACTCAAACAGCAACTGGTCCAAGAACTAAACGCCCTGGACGCCAGCAACGCCCAGCTGCTGGCCGAATCAACCCAGCTCAGCGCTGCCATTAAATTCGATGTAAATACCGCTCTGCCCGCCTTGGAGCCCCAAAAGCTGAACACGCAGCACGTTCAGCATCTGATCGAGCTGTACCAGAGCCATCCGCGTCTGTGGGATCAATCGCATCCGGAGTTCCGGGACGTGGATCGCGGCCGCGAATCGTGGCGCCAGATAACGGACACTTGGAGCGCCCACTGCGGACGCAGCTTTAGCGTGACGGACGTCCGGATACGGATCTCGACGCTGTGCCAGCGTTTTCTCAAGCAGCGCGAACGCATCGCCGCCGAGGGTGAACTGGAGGAGGGCGTCAAGTTCGTCCATTACGATCAGCTGCGCTTCCTGTGCGAGCAGCAGTCGCTGCTCAAGCGCCAGGAACACTTCGCCCGCGAGAATCGCAAGCTGCTCGAGTTCTATGAACACTATCCCATACTCTGGCACAATGCCCACAAGCGCCTTCGCTGCGCCGAAACCCTGCGCCAGCGCCACGAGGCCCATCGCGGCCTTCAGCTGGCGCTGCGCATGTGCGGCATCAAGTTGTCCGGCCTGGCCATCCAGCGGCGGCTGCAGTCGCTCCGCAAGCGTTATCGGCTGGAGAAAATTAGGTATCTGCACTGTGTCGTTGAGGGCAAGCAGGCCGAGTTTGTGTCCGTGTTCGAGCATTATGCGGAAATGGAATTCCTGCACAAACACATCGATCCCTATGTTTGTGCCGCCTGCGGCAAGATCTTTGAGAATCTGGTGGGACATCGAACACATGTCCAGGGCAGCTGCGAGGAGCTGGCTGCTGCCAAGAGCGTGGGCGAGCAGGTTCTCGAGCAGAGCGAAGCTCAGGCGCCGGACACGGATGCAACGGTGGGCGAGCTAATGGCGCTTATGGAAATGGAGGAAGAGCAGCaagtggagcagcagcaaattgagCCAACTGTGGTTGAGCAGCTGGAAacgcagcaggagcagcagcaactggaaaCGAACCAGGCAAACGAGCTGCAAATGGAGCAGCAGGAAGAGGCGCAAACAAAGCCAGATGAAATCACAGCCATGCCGTGTCCAGTGGAAGCGGAAATGGAaggggaagaggaagagaaacaGGAAGAGGAGTACGACTTGGAGGATGAGACAGCTGAGTCAGAGATGAGTCTGTTGGGCGCCCATGGCATTAAGCTGCGCATGCGTCTCAGCCTGGAGCTGACCCATCAGCTAATCGAACTGTATCAGGCGCATCCGAATCTGTGGGATCCCAATCATCTGGACTACCATGCGCGCAAGGTGCGTCGCCAGGCCTGGCACACAATAGCGGCCCAGCTGAACGCCTACGCCGGAGGCGTGGCACGCTTCAGCTGGCAATCGCTGCACCGCAAGCTAACGGACTACATCAAATACTATCGACGGGAACGACAAAGGGAGGCGCTCGCCGTTGTTGGCGCCGGCGAGGGCACACGCTGGGGCTTCTACGAGGCGTTCAGCTTCCTGGACGATGTGGTGCCCATCAATTGTGTGCTCCAAAagtcgctgcagcagcgcgaCAGCAATCTAAAGATCATACAAATCTATCAGAGCTACGAGCAGCTCTGGTGCACCGATCATCCGGACTATACCAAGCgcaagcagcgccagcgccatcTCGAATCCCTCTGCACACGCCTGCAGGAGGAGTGCAATCTCCAGATAACCGTCGAGCGTCTCAAGAGTCGCCTCATCGACTTCCGCTGCCAGTACAGACAATGCAAGGCGGCACGCCAGGCGGCTCTCAACCGCGGCGACAGCTGGCAGCCCAGCTACGAGTATTATCGGGCGCTCCAATTTCTCGAGCTGCACGTTTCGCCCTTTGGCTGCGGCCAGTGCAGCGCCAGCTTTAAGCGGCGCAGCGACTATTTGCGGCATCAGCGCAATGTGCatgtggagcagctgcagcgtcagCTGGACGGCGCCGTCGAGCAGCTGCGTCGGCGGCGCGGCGTCAGCGGCAATCCGCTTGAGCACATTTGCCATATTTGCGCCATGAAATTCTCGCTGCGCACCAGCCTCCAGGCCCATCTACGGCGTCATCTTGGCCAGCGGACGCACGCCTGCAGCGAGTGTCCCAAGAAGTTCTTTAACTCGACCTCGCTGCGCGTCCATCAGCGCAGCCACACCAAGGAGCTGCCCTATGTGTGTGAGCATTGCGCCCGCGGCTTTGTCAATGCCAGCAAACTCAATCAGCACGTCAAACGGCATACGGAACAACGCGACTTTCCGTGCAATCGCTGCGAGAAGGCTTTCTATACGGCCCACGAACGCGATCGCCATTTGCGCGCCCATCTCAATATCCGGGACAAGGTGTGTCCGTATTGTTCGCGCGCCTTTGTCGTTGGCAGCGCCTACTATGCCCATCTCAATCTGCATCGGGGCGAGAAGCGTTACGGCTGCGCCGACTGCGGCCAGCGGTTTGCCCAGTACGCTGGACTCTACAAGCATCGCAAGCGCTGCAAGGCCAGCGAGGGCGACAAGATGTGA
Protein Sequence
MTPAAWAAVAATGAAVGAAAGTATVGAAIEATAGPVEEPRQRCGTVYTWNCAGELYGIECELCEERPLCALDEFAEHMELWHADWQQAPVDELMLEVLAEQSSGGEVNELKQQLVQELNALDASNAQLLAESTQLSAAIKFDVNTALPALEPQKLNTQHVQHLIELYQSHPRLWDQSHPEFRDVDRGRESWRQITDTWSAHCGRSFSVTDVRIRISTLCQRFLKQRERIAAEGELEEGVKFVHYDQLRFLCEQQSLLKRQEHFARENRKLLEFYEHYPILWHNAHKRLRCAETLRQRHEAHRGLQLALRMCGIKLSGLAIQRRLQSLRKRYRLEKIRYLHCVVEGKQAEFVSVFEHYAEMEFLHKHIDPYVCAACGKIFENLVGHRTHVQGSCEELAAAKSVGEQVLEQSEAQAPDTDATVGELMALMEMEEEQQVEQQQIEPTVVEQLETQQEQQQLETNQANELQMEQQEEAQTKPDEITAMPCPVEAEMEGEEEEKQEEEYDLEDETAESEMSLLGAHGIKLRMRLSLELTHQLIELYQAHPNLWDPNHLDYHARKVRRQAWHTIAAQLNAYAGGVARFSWQSLHRKLTDYIKYYRRERQREALAVVGAGEGTRWGFYEAFSFLDDVVPINCVLQKSLQQRDSNLKIIQIYQSYEQLWCTDHPDYTKRKQRQRHLESLCTRLQEECNLQITVERLKSRLIDFRCQYRQCKAARQAALNRGDSWQPSYEYYRALQFLELHVSPFGCGQCSASFKRRSDYLRHQRNVHVEQLQRQLDGAVEQLRRRRGVSGNPLEHICHICAMKFSLRTSLQAHLRRHLGQRTHACSECPKKFFNSTSLRVHQRSHTKELPYVCEHCARGFVNASKLNQHVKRHTEQRDFPCNRCEKAFYTAHERDRHLRAHLNIRDKVCPYCSRAFVVGSAYYAHLNLHRGEKRYGCADCGQRFAQYAGLYKHRKRCKASEGDKM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-