Basic Information

Insect: Drosophila lacertosa
Gene Symbol: L
Assembly: GCA_004143845.1
Location: SCDZ01000512.1:86113-95081[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6.4e-06 0.00067 20.2 2.9 1 23 123 145 123 145 0.98

2 16 0.22 23 5.9 6.2 1 23 151 173 151 173 0.97

3 16 1.1e-07 1.1e-05 25.8 3.2 1 23 179 201 179 201 0.99

4 16 7.8e-06 0.00081 19.9 0.4 1 23 207 229 207 229 0.99

5 16 0.008 0.84 10.4 0.1 2 23 312 336 311 336 0.93

6 16 0.00082 0.086 13.6 0.7 2 23 356 378 355 378 0.96

7 16 0.0036 0.38 11.5 0.1 2 23 434 455 433 455 0.91

8 16 0.00028 0.029 15.0 0.1 1 23 463 487 463 487 0.92

9 16 8.7 9.1e+02 0.9 0.4 2 20 493 511 492 512 0.91

10 16 3.1 3.3e+02 2.3 0.9 2 23 524 546 523 546 0.94

11 16 0.0016 0.17 12.7 1.1 1 23 594 617 594 617 0.97

12 16 0.013 1.3 9.8 1.1 2 23 743 765 742 765 0.96

13 16 0.072 7.5 7.4 0.1 1 23 771 793 771 793 0.92

14 16 0.49 51 4.8 0.3 2 23 801 822 800 822 0.93

15 16 0.11 11 6.9 0.0 1 23 883 905 883 905 0.95

16 16 0.0002 0.021 15.5 1.1 1 23 910 932 910 932 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6.4e-06	0.00067	20.2	2.9	1	23	123	145	123	145	0.98
2	16	0.22	23	5.9	6.2	1	23	151	173	151	173	0.97
3	16	1.1e-07	1.1e-05	25.8	3.2	1	23	179	201	179	201	0.99
4	16	7.8e-06	0.00081	19.9	0.4	1	23	207	229	207	229	0.99
5	16	0.008	0.84	10.4	0.1	2	23	312	336	311	336	0.93
6	16	0.00082	0.086	13.6	0.7	2	23	356	378	355	378	0.96
7	16	0.0036	0.38	11.5	0.1	2	23	434	455	433	455	0.91
8	16	0.00028	0.029	15.0	0.1	1	23	463	487	463	487	0.92
9	16	8.7	9.1e+02	0.9	0.4	2	20	493	511	492	512	0.91
10	16	3.1	3.3e+02	2.3	0.9	2	23	524	546	523	546	0.94
11	16	0.0016	0.17	12.7	1.1	1	23	594	617	594	617	0.97
12	16	0.013	1.3	9.8	1.1	2	23	743	765	742	765	0.96
13	16	0.072	7.5	7.4	0.1	1	23	771	793	771	793	0.92
14	16	0.49	51	4.8	0.3	2	23	801	822	800	822	0.93
15	16	0.11	11	6.9	0.0	1	23	883	905	883	905	0.95
16	16	0.0002	0.021	15.5	1.1	1	23	910	932	910	932	0.97

Sequence Information

Coding Sequence: ATGTACAGCACGCACACCTCCTCCAGCTATTCGCCCAGCATCTCGGACGGCACTTTGACGCCCAACTCGCAGCTGCCCGGCCCGACGGACGGCGACTCGAAAGTTAACGGGGATGCTGCGGAGGAGCCGCAGGAGTCGCTTAAACCGAAGCGACCCGCACACTTgctgcatcatcatcatcatcatcattatcatcatcagcaggCGCTGAAAATTGCCAACAAGCTGCGGAAAATCAATAAGGATGCGAAGctaacggcaacggcggcaggAGGTGGACCCGGCCCAGGATCTGGGCACGGTGCAGCGGGCGCAAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGCCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACCTCAAGCATCACGTGCAGAGCCACGCGGAGCATTTGCCTTTCAAGTGCGAATATTGCGCCAAGCTTTTCAAGCACAAACGCTCCCGAGATCGCCACAAGAAGCTCCACACGAACGAACGGAACTACAAATGTCCCCACTGCGAGGCGGCTTTCTCCAGAAGCGATCATTTGAAGATCCACATGAAGACGCACGACATCCAGAAACCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACGGCGGCGGCTCTCACCTCCCACATGCAGAAGCACAAGAAGAACGCGGCGATTTTGGCGGCCGGAGGAAATCCGAATGCGTTGAATTACAGTCCACGGTCGACGGGCTCCGCCTCCATATCGAGTAACGGTAGTTTGCACAAGCGACGCTATGCGCTGGCCTTGGCCGCTGGCTCCGACAGCAGTCCCAGTCGCCTCGAGTTCCCCAAGCGGGCGCGTAATCAATTGCCAGCAACgccgacagcgacagcgacgccgactgcgacgccgacgccgctgctgcgctGCAGCTACTGCCCGAAGGCGACAGAGTTCAGCAGCCTGGAACAGCTAAATGCGCATCTGCAGAGCGtccacgagcagcagcagccagcggaCAGAGATGCCTCGGAGCAGCCAAATGGCTTCCAGCTAAACTGCGAATACTGCACGATGAAGTTTGGGAATATTGCGACGCTCTTCCAGCACATGCGGAGCACCCATCTGGATCGGCTCAGCAGTCCCAACTCCTACTACGAGCACTTCAATCGACTGGCCAACACGGGCACCTTCAGTCCGCCCAGGGTCAAAGCGGATCTGTGCAGTCTGCCGGATTTCGAGAGTTTCCGCAATCATCTAAAGAGTCACATCGCCGAGGGCATGCAGCTGAGCTGTCCACACTGCGGACTCAGTCTGCCGGAGCAGAGCGAATATGAGCGTCATGTGGTGGCCCATTTTCTGATCAGCAGCTCGGAGTTTAGCTGCGGCGCCAGCTGCGGCAAGTCCTTTGCCAAGGCggaggagctgcagcagcatctgctgGGCGAGCAcgtccagcagctgctcaagtGTTCGCTGTGCTCGGAGCTCTGCGAGAATCGCATGTCCATGCAGCTGCATCTGGCCTGTGCCCACAGCGCGCCCGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAACTCTTTCGATCCGATGCCGAGTTCCATGTGCACGTCAAGACGCGTCATCAGCTGAATGGCCAGCAGAATGCTGCAGTTGGTCCTCTGGCGGCCGCTGCTCCTGCGAATCCTTTGCAGTGCATGTTCTGTCGCATCGTTTGCGCCTCCGAGCTGGAAATGCATTTCCATTTGGCCGCCCATGCGCGCCAATTCCGCTGTCCCAGCTGCCCGGAAACCTTCCACGTCGAGTTCCTGCTCGACCGTCACATGCAGAGCCAGCACGGCGGTCTCTTTGGCAACAATgcaacgacgacagcgacgtcgacgccgacgccgacgcaggctgcgactgcggcagcggcagcggcagcgagtGGTGGCAAGTTTTACAGTCCGCTGCAGGTGGACACAAAGGCGCCGCATCCGGCGCTGATGTACGGCCTCAGCCAGCGCTATCTGATGGAAATGTACGCGGCCAAGGCGAGCTCCCCCTcagccaacgccaacgccaacgagACGCCACCaaatgtggcagcagcagcaaccgttGCTGGCAACTTCAGCTGCGGCATGTGCGAGCGCCAGGATTTACGCAGCGAAGCCGAACTTCATTCGCATCGCAAGCTGGCCCACAATCTGAAGACGGGCGTCAGTCTGAGATGCGCCTACTGTGCGGGCAACTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGTTGCCACAACTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCCTCGCCCGCTATACTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGTGCCCACTGTGGCCAACAGCTGGAGCACGTGGCCGCCTATCGAGCACATCTGGGCGAGCACGGCAACGATGGCAATCTGCCCATGGCCTGCATCTGTTGCCGGCAAACGCTGCACTCCGAGTTCGAGCTGAGCCTGCACGCCAAGTTCCATACCAAATCTCCGGGCAGCGGCAGCCTGCAGGAACCTAAGCTGCAGGAGCATCTGGTGGAGCACACGTTCGCTGGGAACGAGCAGCGCGGCTTTAACTGTTATATCTGCTCGGCGGTATTTACAGCGCCCGGCGGCCTGCTCGGCCATATTGCCGAGCACGGCGCTCGGCCCTACGACTGCAGCCTGTGCCCGGAGAAGTTCTACTTTCGCGCCGAGCTGGAGCATCATCAGCGGGCGCACGAGCTGCGGCCGCGTGTCGCCGCCAAACTGGAGGCCAGCTCCCCAACACAGCCGCCGCCAGCTGGCAGTCCGCTGCAGGCGGTCAAACAGGAACTGTTCGAATCGGAGCCGGCGACGTCGCCGCCTCAGCCGCAGACGCCGCCCCCGGACGAGGAGGAGTATATCGAGGTGGAGCAGGTGCCGCAGGAGACGCAGCGCGACGCGAATCAACTGAGTGCGGAGCgttccagcagcagcgcataA
Protein Sequence: MYSTHTSSSYSPSISDGTLTPNSQLPGPTDGDSKVNGDAAEEPQESLKPKRPAHLLHHHHHHHYHHQQALKIANKLRKINKDAKLTATAAGGGPGPGSGHGAAGAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALAAGSDSSPSRLEFPKRARNQLPATPTATATPTATPTPLLRCSYCPKATEFSSLEQLNAHLQSVHEQQQPADRDASEQPNGFQLNCEYCTMKFGNIATLFQHMRSTHLDRLSSPNSYYEHFNRLANTGTFSPPRVKADLCSLPDFESFRNHLKSHIAEGMQLSCPHCGLSLPEQSEYERHVVAHFLISSSEFSCGASCGKSFAKAEELQQHLLGEHVQQLLKCSLCSELCENRMSMQLHLACAHSAPETKLLRCSACLELFRSDAEFHVHVKTRHQLNGQQNAAVGPLAAAAPANPLQCMFCRIVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGLFGNNATTTATSTPTPTQAATAAAAAAASGGKFYSPLQVDTKAPHPALMYGLSQRYLMEMYAAKASSPSANANANETPPNVAAAATVAGNFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAYRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGSGSLQEPKLQEHLVEHTFAGNEQRGFNCYICSAVFTAPGGLLGHIAEHGARPYDCSLCPEKFYFRAELEHHQRAHELRPRVAAKLEASSPTQPPPAGSPLQAVKQELFESEPATSPPQPQTPPPDEEEYIEVEQVPQETQRDANQLSAERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -