Dlac009203.1
Basic Information
- Insect
- Drosophila lacertosa
- Gene Symbol
- -
- Assembly
- GCA_004143845.1
- Location
- SCDZ01000313.1:16694-21352[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.00083 0.087 13.5 1.1 1 23 224 246 224 246 0.96 2 21 0.16 17 6.4 4.4 1 23 252 274 252 274 0.97 3 21 0.11 11 6.9 1.3 2 23 306 327 305 327 0.95 4 21 0.015 1.6 9.6 0.9 1 23 404 427 404 427 0.93 5 21 0.73 76 4.3 4.1 2 23 438 461 437 461 0.93 6 21 2.8 2.9e+02 2.5 1.0 1 23 467 490 467 490 0.93 7 21 0.036 3.7 8.4 0.9 1 23 502 524 502 524 0.98 8 21 0.00018 0.018 15.7 1.3 1 23 601 624 601 624 0.98 9 21 0.021 2.2 9.1 0.1 3 22 635 654 633 654 0.93 10 21 0.33 35 5.3 5.5 1 23 663 686 663 686 0.95 11 21 0.0006 0.063 14.0 0.2 2 23 716 737 715 737 0.97 12 21 1.3e-05 0.0013 19.2 5.4 1 23 745 767 745 767 0.99 13 21 0.017 1.7 9.4 0.8 1 23 918 941 918 941 0.95 14 21 0.0065 0.68 10.7 0.9 2 22 949 969 949 969 0.95 15 21 0.076 7.9 7.4 0.4 1 23 978 1001 978 1001 0.92 16 21 2.1e-05 0.0022 18.6 1.5 1 23 1026 1048 1026 1048 0.97 17 21 0.00031 0.033 14.9 0.7 1 23 1055 1077 1055 1077 0.98 18 21 0.0046 0.48 11.2 0.0 2 21 1104 1123 1103 1124 0.94 19 21 0.028 2.9 8.7 4.0 1 23 1169 1192 1169 1192 0.96 20 21 0.039 4.1 8.3 0.6 1 23 1229 1252 1229 1252 0.96 21 21 0.01 1 10.1 3.1 1 23 1277 1300 1277 1300 0.97
Sequence Information
- Coding Sequence
- atgTTGCCGTCGGATATTTGTCGCACGTGCGCGCTGCAAGTGGACAgcttgctgccgctgtcgacGCGCACTAATAAATACGCAAATAAATGCCTGAACGACATGTTGCACGAATTGACGCAGAATGACCCACTGCAGGAGCATGCAGATGAAAACCTGCCCCAGCATTTGTGTGACGACTGCATGGGGAAACTGGAGGCGGCCTATGCATTTGTGCTGCAGGCGCGCCAGTCACAGGAGCAACTGTTGCTCCAGCTGCGCAAAGGATTGCAGACGCAGTGCCTGGACGAGGTGCCCATTGACATCGGCATGCAACAGATAAAAACCGAAACGGACCTAGACTTGCCCGTGGGAAAAACCAAAAGCGAATTAACAGTGCAGGCTGAGAGGGAACAGGAAGAGGAGGAATTGGATGGGATTGATGCTGTGTCAGTTGCCGCCTTAAAATGGCAGCCGGATAGCGATAGCGACTGCTGTCGGCCAGCAATTGATAACAAGGATGAGGACTTCAAGCCCAAGCAGCTGCGGCGTAGCGCACGTAAAGCCAAACTGGCCACAGACAGCGAAAGTGAAGACAACTCTGCCAATGCGAAGCCCGAGCCTGTCAAGCGGCGTCGTGGTCGGCCGCCTCGTGCAGCCAAAAAGGAGACAATTAACGAGGACGGTCGTCACGCGTGCGAAGTCTGCGGCAAGACATTCTCCTGGTATCGCGACATGCAGCGTCACGCACGCAGCCACTTCGAGCAGGCCGCCTTTGTGTGCGACAGTTGCGGCAAGTGCTTCCTGCGCAAGGACAAGTACATGTTCCATCTGCGCTCGCACGAGAAGCGCGCCGCCAAGTGGCAGGCGTTGCAGCTGAGCGGCGAGTGGCGTTTCGCAGAGCGTCTCTACAGCTCGGCGCGGCTGAAGCGAGTCGAGTGCAAGCTGTGCGGCCTAAAGTGTCAGCGCATCCAGGAGCTGCGTGAGCATCTAACCAATCACACTCAAACTGAAACACTATCCAATTTAAGTCTGGAGGCGGATGTCATCAGAGAGCGGTTTGGCggcgaacagcagcagttggATTTGGAGCAGATCAAGCAACAGGTGTGCGCAGATATTGCCATGGGACGGGAGCAGCTGAACAATTACTGCGCTGTGGTCAACGCTTATGGCTACGAGCTCTGCCTGAGCGACTCGGATGAGGAGCCGGTCGGCATGGTGCCCCAATACCAGTGTCTGCCCTGCAGCGTTTCCTTTACGCGCAAATATCGCCTCATGCGGCACACGCTGGAGGAGCACACGCAGACGGAGTCGGATATGACCTGGCAGCGCTGCGATGTTTGTCAAATCGGGTTCGTGTGCAAGCGGCTTCTGGAGCAGCATCAGCGCACGCAGTGCCACAATCCAATGAAGCGCTACAGTTGCTCCAACTGCCCAGGCAAATTCATGTGGCTGCAGAATCTCGAGCAGCACGCGTGCTCCCAGCACAGCAGGCCGCAGGAGGAGCATCCAATGCGTCAGTTCCAGTGCTGCCTATGCGATGCAACGTTGCAGAGCATGGCAACTCTACGCGTCCATTTGCTCACCCATCGCGACGGCTGCAGCGGCATCGATGTGGATCACCAGGCTGCCTTCTTTCGCACCTACCATGCAGATGGCCTCGACTGCAGCCCGGACGAGCTGAGTGCGCGCATTGCTGGCGACTTTGAGGCACAAAACTATGGACGCTATTTCAATGCCAGCACAGCTAGTGGTCAGGAATTGGACTTCTTCGCCTCAGACACGGATCTAAGCGATACGGAGCAGCAAAGCGCTTTATATACATGCTGCGTGTGCGGCGAGTCCGTGGCGCGCCTaacacagctgctgcagcaccagCGTAGACAGCACAAGGAGCTGCAGAACAGTTTGCCGCATCTCTGCGAAGACTGCGGCTTGGGCTTTGTGGCCGaagcgctgctgcagcaacatcgTCGACGCGTATGTGGCAAGCGGCAGGCTAAGTTCCATTGCCAGGAGTGCGGCctgcatttttattggcaCGACAACTACGAGCGGcacttgcagctgcagcacgaGACAGAGGTGGACGCGGAGCAAGAGGCGGACACGGAGGAGTTCAGCACCAGGCTGCGAAGCAGGCGTCAGCCAACTGCTAAGCTGCAGTGCGGCGAGTGTGAAAAGGTATTTGTCTGGCCCAAAGATCTGACGCGGCACAAGCGTCTGCATCAGCCGCAGGCACTGGCCCAGTACGAATGCACGCACTGCGACCGCAAGTTCCACCGCAAGGATGGCCTCAAGTCGCATCTGCGCGTGCAcggcgagcagcagcaggagtcCGTAATTGCCAGCGATCCTCCATTGTCTGTACTGCAGCGCATGCCGATGGTGTTGACCCAGCTGTGTCGGCCCAACGGCTGCAAGCAGATTCAGTGCATGATTTGCCTGTCGCAGCACTCAAAGATCTCCGATCTGCGCACTCATTTGCCCAGCCATCAGCAGGCGCTGCAGTTCCTGGAGGAGCGTGGCCAGCCAGAGAGCATAGCCACCATTTGCCGTACTCTGTACCCCGAGCTAAGCATGCCGTTGGCAAAGCAACCGCTCATCGAGCGCATACAGAGCGACCTGGCCGCAGGCGTGGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGGCATGGAGCTAAGTCTGGACAGCAGCGAAACGGACTCCGATTCGGACTGCGCCgaggcagctggcagcagcagcagcagcaacgggcGCTTTTACAGCTGCGAGCTGTGCCAGCTGCAGGTGCCGCGCAAGCACCAGCTCTATGCTCATCAGCTGGAGCAGCACACGTGGCAGCAGGCGACGCGCGTGTGCAGCCACTGCCAGGCGCGCTTTGTGagcgagcagctgctggagcaTCATTACCGCACGCTCTGCCGGAACGCCCAGCGGCGCTTTCTTTGCCGCAAGTGCCCGTTGCGCTTTCGCTGGCGCGAGAATCTCAAGCTGCACACGGCCGTGGCGCATCAGGAGTCGAGTGCGGAGCAGGCGAACTCGGGCATTCAGTTGAATGGCACGCATCTGCTGCCCGTGGTCAGCTACGATTGCGGCGAGTGCAAGCGCAGcttcaaaatgcaaaaggaTCTCACGCGGCACACGCTGATGCACGCCCAGGAGTCGAGCATTTATCGGTGTCGCTGGTGCGCCCGTCGCTTCTATCGCGAGGCTAATCTGCTGCAGCACATCGAGCGACATGGAATCAGCGCAGAGCAGCTGCCCTATGCGGAGGCGCTGCTCAACGCCAGTCGGCATCCGCATGGCACCAAGTGCATCCAGTGCAAAGTGTGCAATGTTTCGTTTCCCACAATTGCCACACTGCGCGTCCATCTGCAGGCGGCGCCGGTGGGCACACATCACGAGATCGGCTCCTTGTTGAACTACTCGATTACCAACCAGCTGGGCtacgagctgcagctggaggacTCGGAAACGGACGAGGAGGCCAAGCCGCCGGGCACGCCTGCGCAGTATACTTGTGGCATGTGCCAGCTGCGCTGCGTGCGCAAGTTTGAGCTGCACCAGCATCAACAGGCGATGCACCGGCTGGAGCGTATTGCCGATGGCTGTGATCGATGCATTTACAAGAGCGTCTCGCCGGATCTCATTGCCTATCATCGGCGTGCGCTGTGCGACAACACGGAGAAGCAGTTCAAGTGTGCCAAGTGCAGCTATCGCTTTATGTGGGAGGCAAATCTGTTGCAGCacatgcagctgcagcatcccAGCGTCGAGGGGCAGCAGGAGGCGAACTCCATGCCTGTGCCGGACATGCCCAGTGCCGAGTGCCAGGTCTTTCAATGCGGTCAGTGTCCGAGTAAATATAATCGCAAGGATCGCCTGACGGCGCACGTGAAGAAATGCCATGCAGCGGGCGCAACGGGCTCGACGGGCACGCCCACAAAGCCGGCGAAGAGTTCAGCAGCCGCCAAGCAGCAGAAGAGTTTTCTGTGCGCGTTCTGCGGCAAGGCCGGCACCGCGCTCAAGAATCATCGACTGCAGCACGGGCACTTTGAGGCGGAGGTGGGTCAAGTAAAGGATGACTAA
- Protein Sequence
- MLPSDICRTCALQVDSLLPLSTRTNKYANKCLNDMLHELTQNDPLQEHADENLPQHLCDDCMGKLEAAYAFVLQARQSQEQLLLQLRKGLQTQCLDEVPIDIGMQQIKTETDLDLPVGKTKSELTVQAEREQEEEELDGIDAVSVAALKWQPDSDSDCCRPAIDNKDEDFKPKQLRRSARKAKLATDSESEDNSANAKPEPVKRRRGRPPRAAKKETINEDGRHACEVCGKTFSWYRDMQRHARSHFEQAAFVCDSCGKCFLRKDKYMFHLRSHEKRAAKWQALQLSGEWRFAERLYSSARLKRVECKLCGLKCQRIQELREHLTNHTQTETLSNLSLEADVIRERFGGEQQQLDLEQIKQQVCADIAMGREQLNNYCAVVNAYGYELCLSDSDEEPVGMVPQYQCLPCSVSFTRKYRLMRHTLEEHTQTESDMTWQRCDVCQIGFVCKRLLEQHQRTQCHNPMKRYSCSNCPGKFMWLQNLEQHACSQHSRPQEEHPMRQFQCCLCDATLQSMATLRVHLLTHRDGCSGIDVDHQAAFFRTYHADGLDCSPDELSARIAGDFEAQNYGRYFNASTASGQELDFFASDTDLSDTEQQSALYTCCVCGESVARLTQLLQHQRRQHKELQNSLPHLCEDCGLGFVAEALLQQHRRRVCGKRQAKFHCQECGLHFYWHDNYERHLQLQHETEVDAEQEADTEEFSTRLRSRRQPTAKLQCGECEKVFVWPKDLTRHKRLHQPQALAQYECTHCDRKFHRKDGLKSHLRVHGEQQQESVIASDPPLSVLQRMPMVLTQLCRPNGCKQIQCMICLSQHSKISDLRTHLPSHQQALQFLEERGQPESIATICRTLYPELSMPLAKQPLIERIQSDLAAGVELERFVSITNEAGMELSLDSSETDSDSDCAEAAGSSSSSNGRFYSCELCQLQVPRKHQLYAHQLEQHTWQQATRVCSHCQARFVSEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRENLKLHTAVAHQESSAEQANSGIQLNGTHLLPVVSYDCGECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISAEQLPYAEALLNASRHPHGTKCIQCKVCNVSFPTIATLRVHLQAAPVGTHHEIGSLLNYSITNQLGYELQLEDSETDEEAKPPGTPAQYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDRCIYKSVSPDLIAYHRRALCDNTEKQFKCAKCSYRFMWEANLLQHMQLQHPSVEGQQEANSMPVPDMPSAECQVFQCGQCPSKYNRKDRLTAHVKKCHAAGATGSTGTPTKPAKSSAAAKQQKSFLCAFCGKAGTALKNHRLQHGHFEAEVGQVKDD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -