Dlac012503.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacertosa
Gene Symbol
su(Hw)
Assembly
GCA_004143845.1
Location
SCDZ01000434.1:85991-89076[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00046 0.048 14.4 2.2 1 20 233 252 233 254 0.94
2 10 1.9e-06 0.0002 21.8 0.4 3 23 305 326 303 326 0.93
3 10 3.5e-06 0.00036 21.0 0.5 3 23 329 349 328 349 0.97
4 10 4.7e-05 0.0049 17.5 3.2 1 23 360 382 360 382 0.98
5 10 5.6e-05 0.0058 17.2 0.9 1 23 388 410 388 410 0.97
6 10 1.1e-05 0.0012 19.4 0.8 1 23 416 438 416 438 0.99
7 10 1e-06 0.00011 22.7 2.6 1 23 444 466 444 466 0.98
8 10 0.0028 0.29 11.9 1.5 1 23 470 492 470 492 0.97
9 10 2.2e-05 0.0022 18.5 0.2 1 21 500 520 500 524 0.92
10 10 3.5e-05 0.0036 17.9 0.3 3 23 544 565 542 565 0.96

Sequence Information

Coding Sequence
ATGAGCGCCAGCAAGGAGGCCAAATCGACTGACGCCCCCGAGGCGAAACCCGCATCCACGTCCGCCCCCAAAAGCGAAGGCACCGCTGTGATCAAAATCGTGGACGTTGAGCAGATAACACTGTCCAAGGAGAAGCGGTCCGGTGCACGCATGAAGCTTTTGAACGATGTGCCCGCTAAATCTGCCAACAAGGCAGGCTCCTCGGCCCGGCCCAAACAGGAGAAGCGAACCAGCATCAAAATACTCAACAACGACGAAGCAGCCAGCACTCCCAAGGGCAGCGACAAGCGCTCCACCGGCAAAACAGCCAGTTCCGCAGGCAGCAGCGTCAAGATATTAAATGAGAAGCGCACTGCGCCCGCTGCCGTCGATGTGGAAACAGCCAAAATCAAGACTTCGcccagcaagaagaagaaaatggatCACTACGTGCTGCAGGCCATCAAGAGCGAGAACAGCAAGGCGGACGTAACGACCAGCGTGGTCGTTGTCGAGGATGATGACACAATTGACTTCATACTCGCCGATGAGGACGTTGAGCTGGGCGCAGCCAAGGAGAACAGCGATGAGTTTGTAGTCGAcgaggaggacgaggacgatgaCGAGGGCGAGGACGAAGACGAGACTGAAGCTGTGGGTGAGGGCAGCACGAATCGCAccagcggcaacaacggcGAGCTCAAGGAAATGGTGGAGCACGTGTGTGGCAAGTGCTACAAGACATTCCGACGTGTAAAGAGCCTGAAGAAACATCTGGAGTTCTGTCGCTACGATAGCGGCTATCATCTGCGCAAGGCGGACATGCTAAAGAACCTCGAGAAGATCGAGAAGGACGCTGTGGTCATGGAAAAGAAGGATATTTGCTTCTGCTGCAGCGAAAGCTACGACACCTTCCATCTGGGCCACATCAACTGCCCGGATTGTCCCAAGTCGTTCAAGACACAGACCAGCTACGAGCGCCACATTTTTATCACACACTCGGACTGCAAGGTATGCGATCGCGTCTTCTATCGCTTGGACAATCTACGCGCCCATCTCAAGCAGCATCTGGGTACGCAGGTGGTCAAGAAGCCAGAGTACATGTGTCAAGTGTGCAAGAACTGTTTCTACAGCCTGTCCACGCTCAACATTCACATTCGCACCCACACGGGCGAGAAGCCCTTCGATTGCGATCTGTGCGACAAGAAGTTCTCGGCCTTGGTGGCGCTCAAGAAGCATCGGCGCTATCATACGGGCGAGAAACCCTATACCTGCACGGTGTGCAGTCAATCCTTCGCTGTCAAGGAGGTGCTCAACCGCCACATGAAGCGCCATACCGGCGAGCGTCCGCACAAGTGCAACGAGTGCGGCAAGAGCTTCATACAGGCCACCCAGCTGCGCACGCATTCCAATACGCATCTGCGTCCCTATTCCTGTTCGCTGTGCATCCAGAAGTTCAAGACAGCTAAACAACTCGTGCGCCATACCAAGGAACATACGCGCCAGAAGCGTCCATCCTTTGCATGCACTGAGTGCACGCGCAGCTTCCGCACCAGCGCGCTGCTCAAGGAGCACATGGACGCGGGCGATCATTCACCTGTGAAACCCACGCGCGCCAAGCGCTCTGCAAAGATGATCGAGCGCACGGACTGCGCCATTTGCGACAAGAACTTTGACAGCACTGAGACACTCAGAAATCACATTCGCAGCGTGCACGAGTGCGATCCAGACGACATCTTTGGCACGCAGCCGTCGGCTAAGCGTAAGTCCAAAAAGGCTgtggcagcagcgacggcgatgGAGGAGCTGGACGATGATGAGGAGCCGGAGGAAGACTTGGCAGCTGCCAATACATCGGCGGGTTCGCTTATCTCCAGCAACACGGACGGCAACGGCGTTGTGGTGCGTGAGTTCCTCGTGGATGAGGGCGATGGCAACGCGCAGACCATTGTTCTCGAGAACGAGGTGTACACAATTCTGCCGCTGGAGGGCGGCGACGCCACTGACGAACCGTCGGCAGAGGATGACGTCAAGGCTGAGTCGAaggagaagcagcagcagcagcagtcggtTTCCCCAGTGGTTAAGAAGGAGCAACGCAAATCGCTGGCCGCCAGCTTGGCCGCTGCCATTGCGGACAACCTAGAGGAGCCGCCGAGCGACGACGAATTCGGTGGCGAGGTGCTCACCGAGGAGGATCTAAAGCTCAAGGAGAACATTGCCAAGCTGATAGACATGCTGGTGGATCCGCAGACCCTAAAGAAGTACGGTTGGCCCAACAGCTCCGAGGAGTCGGTGCTGTGCAAGGTCATCGAGAACTGTGGCCACGACCTGGCCAAAGGCGGCGAAAACTACGCCGAGTTGGACTACGGCAGTCGCATGCGCGAGTACTGCAAGCTCCTGTTCACGGTGGTCATTCACAACGATTCCATAAAGGCGCTGCTCAACAACTTTCCCATTGACGATGTCATTGAGTATGTGCTGGGCGACGAGGatcaggaccaggaccaggaccaagATGCGGATAAGGACAAAGACAAGGAGGCCGATAAATCAGACACGGAGGAGACCACACCTGAAACCGTGGACGCCGAGGCCTAG
Protein Sequence
MSASKEAKSTDAPEAKPASTSAPKSEGTAVIKIVDVEQITLSKEKRSGARMKLLNDVPAKSANKAGSSARPKQEKRTSIKILNNDEAASTPKGSDKRSTGKTASSAGSSVKILNEKRTAPAAVDVETAKIKTSPSKKKKMDHYVLQAIKSENSKADVTTSVVVVEDDDTIDFILADEDVELGAAKENSDEFVVDEEDEDDDEGEDEDETEAVGEGSTNRTSGNNGELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSDCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCQVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSNTHLRPYSCSLCIQKFKTAKQLVRHTKEHTRQKRPSFACTECTRSFRTSALLKEHMDAGDHSPVKPTRAKRSAKMIERTDCAICDKNFDSTETLRNHIRSVHECDPDDIFGTQPSAKRKSKKAVAAATAMEELDDDEEPEEDLAAANTSAGSLISSNTDGNGVVVREFLVDEGDGNAQTIVLENEVYTILPLEGGDATDEPSAEDDVKAESKEKQQQQQSVSPVVKKEQRKSLAASLAAAIADNLEEPPSDDEFGGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQDQDQDADKDKDKEADKSDTEETTPETVDAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00495995;
90% Identity
-
80% Identity
-