Dkur013489.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kurseongensis
Gene Symbol
-
Assembly
GCA_018153305.1
Location
JAECXX010000005.1:6937062-6940342[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.00022 0.016 15.6 5.2 1 23 737 759 737 759 0.97
2 7 0.00072 0.054 13.9 0.3 1 23 765 787 765 787 0.98
3 7 0.00039 0.029 14.8 0.9 1 23 793 815 793 815 0.99
4 7 4.7e-07 3.5e-05 24.0 0.5 1 23 821 843 821 843 0.99
5 7 2.7e-06 0.0002 21.6 0.4 1 23 849 871 849 871 0.99
6 7 2.8e-06 0.00021 21.5 0.6 2 23 878 899 877 899 0.97
7 7 0.00065 0.048 14.1 0.4 1 23 905 928 905 928 0.96

Sequence Information

Coding Sequence
ATGTCAGACATGCTGAAAATGGCAAATGTTGCAAATCCGCTGCAAACAATGAAGAAAACAAACGGGGACGAGGATTCCGAGGAGTCTGATATGGAAGATCAGGATGAAGAGGAGGAGGAGGAGGACGATCTCCCGGACGATGTGGTGCTCCAAATCGACAGCGAAGATGAGGCAGAACTGGAAGCGCAGCGCATCCGCTTGGTGGAAGAAGAAGCAGCAAAGACAACAAAAATTGCAGAGAAAGAGCAACAGCAACAAAAAGAACAACAACAAGCGCAGGTCAGTAACGGTAACGAAGAGCAACTGGAGGAAAATGGAAAACCGAACAACAATAGTAAACGCAAGGGCCGTGGAAGACCCAAACGCAGGGCTTCCACTAGCTCGCAGGCTTCCAGTGCGTCCATTGCGTCCATTGCGTCTATAGCTTCCCTCGCTTCCAGTGCTTCCCTGGTGGCAGCACAAGTTCTCGCGGATGAAAAGTCACGCCGCTTTATCTACAGCTGTTCCAGCTGCACTCACCACTACGCCGATAGCCTGATCCTCTCGAGACACTTCCAGGCGGAGCATACCGAGAAGCCGAAGAAGAAACGTGGTAAGACCAAGTGGGGTTCCCTGGAAGAACCTCTGCATATAACAACACCCCTGACCCTTGACCCTTTGGAAATGGGTCACCTCAAGCCCTGTGCCCAGTTGCTCGTCCAAGGGGAATCCCTGCTGCAGCTGTGTCTCGCCTGCAACTCACAGTTTGTGGATGAGGTACGTTTTCAGGAGCATCTCAGCCAGCAACATGGTTATTTCAAGTTACTGGTGCCCAAGGAGGAGCCCACCGATCTCCCGCCTCAGGCCATGGTCACCATTCCGGGTGCTTTGGCCCTGAGCAAGGCCAATTCCCAGCTCCAGCTGCCCATTCCAGCTCCAGAAACTCCGCCACCCGAGCAGGATGCCAAGGAATCGCCAACGAATACCGGGTCTAATGACAAGGAGGATCTGGCCTTAATCAACGCCATGGTTGCCGAGATTGCAGCCGACCGGGTGAAGAAAACCAGCAGTCCCAAAGTCAGCAAGATGATTATCAAGCTGCCCATGTGCAACAAAAGAGGTAGAAAAAGGTCCAAACCCGAGAAGATCAGGGACGGCAAGGAGAAGTCAGAGAAGAGCCGCGAGAGGAAGCAGGTGAAGCCTGAGAAGAAGAAAAAACTCGATGTAGAGATGGAAAAGCAGCAGGAGAAGGATGTTTGGGATCAGCAGGAACCAGAGGGAGATGAAAAAAAATTGCAAAAGTCGATGTTCGTTGAGAAAGACCAACAAAAGCCTGAAAAGTCGGAGAAAGAAGTCCAGCCGACGGCTGAGGAAGTTGAAAAAGAGTCCAAGCTTTCGGAAAAAGTGGAGAAAAAAGAGCTGCCGCTAAAAAATTCTGTTACGGAGCAGCACGTTATACCAAAAGCTATATCAGATGTGCAGTCGTTGGTCAATGACTCAAAGGGGGAGTCAACGCTGAAAAAGTCTGAAAAGGATAAAAACTCTACGGATAAAGACTTAAAAAACAAGCCTTCCAAAGACAAACAATCGCTCGCAAAAGCAGTTAAAGCAAAGCAACTGCTGGAGGAAACTGTTAAGGAAAAGCAGCCGCTTGAAAAAGATTCACAAGAGCTAAACAAAGATGGTATTGAGACAGAGATGCCAAGCATTGGTAAAGATGATCCACAGAAACAGGAGAATGATAAAGATCAGACACAGCTGCTTAAAAAAGTTGACAAAGAGACGCAGTTAGAAATACCAGGACAGAATTATGTCCAGCTAGAAAAATCAGTAAAATCGAGACATGCTGAGAAAGAGCAGCAGCGAAATTCAGACAAAACGCATAAGGATCAGCAGCATCCGGCAGAGGAAATCCCTAATCCAGCAAAGCGCAAGCGCGCCCGTAAAGAGCGCAAGTCGCCCACACCCGTACCCGTCCCGCTTGAAGAGATCAAAGAAGAGTCAGAACCACCAGAGCGGCGCACGCGCAAGTCCCGTCACCAGGTGCACTACGTGGTGGATATCAAAGATGAAGAGGAGGAAAAGGAGGACGACGAGGAAGAGGAGGCTGAGGTGGATGACGACTCCTCGGCCACTATTTCGCCGCACAACAGCTCAACGGACGGCAGTTTTACATCGATCAAACGTGAGTCATCCGAAGAGTCGCTGCGCAATGGAACTGGAGGCATACACACCTGCAATTTCTGTGGCAAAACATTCAAACGTTTCTCGAGAATGCAGGATCACTTGCGGCTTCATACTGGAGAGAAACCATATGTTTGTGGGCAGTGCGGCAGGGCCTTCCGCTTGAAGATGCGTTTGGTGGAGCACCAACTGCGTCACCGCACAGAAAAGGCGTACAAATGCGAAATTTGTTCAATGCCACTAGCCACCAAACAGGATTTATCGCTGCACATGCGTCATCACAAGAACGATCGGCGCTACAAGTGCGACAAGTGCAACAAGGGATTTGTTCGCAGCTCAGATTTGTCTATCCACGTGCGGATTCACACAGGCGAAAAGCCGTATAGTTGCGATCTGTGCGGCAAGGCGTTCCGTGCTCGTCAGAATCTGGTGGTACATCGACGCACTCATCTCGGCGATAAGCCCATTCAGTGCGAGCTGTGCGACAAGCGTTTCGCTCGGAAGATCGACATGCGGGTTCACATGCGCAGACACACAGGTGAAAAGCCCTACAACTGTGACGCTTGTCAGCGTGGCTACTCTTCCCGTGTGAATCTGTTGCGCCACCAGGAACGTGAGCACGGCGAGGAGGAGAAGACCTCTGGATCTGTCAAAGCAGAAAAGAAAAAACCAGAGCCGGCGAAGGAGACGGAGACGGAAAATCAACCCAAAGCCAATCCAGCGCCTCGACGTCCGCGACGCGAGAAGCTGCAGCAGAAGATAGCGGCTCAGGAGAAACTACTGGATGACCTGAAACGCAGTTTGAGTGCCCTGCCAGAAATCTCCGAGGAGTCATCACAGGCCAAACTTGAATTGCCAGCAGATGCGGGAGCAGGGCGTGCCCAGGTACAGGTCACAGTGTCCATGCAAATGGAACCAGCACCAAATCCCGAAGACGATGAGGAGATCACACCAGAAAAGGAGAACGCTTTGTCAAGCTCATCGACCGCCGATAGCAAGACAAAGGCGAATCGGAAGATCACCAGCTACTTTACTGTTGTAGGTCAGCAGGCGGAAATCTAA
Protein Sequence
MSDMLKMANVANPLQTMKKTNGDEDSEESDMEDQDEEEEEEDDLPDDVVLQIDSEDEAELEAQRIRLVEEEAAKTTKIAEKEQQQQKEQQQAQVSNGNEEQLEENGKPNNNSKRKGRGRPKRRASTSSQASSASIASIASIASLASSASLVAAQVLADEKSRRFIYSCSSCTHHYADSLILSRHFQAEHTEKPKKKRGKTKWGSLEEPLHITTPLTLDPLEMGHLKPCAQLLVQGESLLQLCLACNSQFVDEVRFQEHLSQQHGYFKLLVPKEEPTDLPPQAMVTIPGALALSKANSQLQLPIPAPETPPPEQDAKESPTNTGSNDKEDLALINAMVAEIAADRVKKTSSPKVSKMIIKLPMCNKRGRKRSKPEKIRDGKEKSEKSRERKQVKPEKKKKLDVEMEKQQEKDVWDQQEPEGDEKKLQKSMFVEKDQQKPEKSEKEVQPTAEEVEKESKLSEKVEKKELPLKNSVTEQHVIPKAISDVQSLVNDSKGESTLKKSEKDKNSTDKDLKNKPSKDKQSLAKAVKAKQLLEETVKEKQPLEKDSQELNKDGIETEMPSIGKDDPQKQENDKDQTQLLKKVDKETQLEIPGQNYVQLEKSVKSRHAEKEQQRNSDKTHKDQQHPAEEIPNPAKRKRARKERKSPTPVPVPLEEIKEESEPPERRTRKSRHQVHYVVDIKDEEEEKEDDEEEEAEVDDDSSATISPHNSSTDGSFTSIKRESSEESLRNGTGGIHTCNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRLVEHQLRHRTEKAYKCEICSMPLATKQDLSLHMRHHKNDRRYKCDKCNKGFVRSSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCDACQRGYSSRVNLLRHQEREHGEEEKTSGSVKAEKKKPEPAKETETENQPKANPAPRRPRREKLQQKIAAQEKLLDDLKRSLSALPEISEESSQAKLELPADAGAGRAQVQVTVSMQMEPAPNPEDDEEITPEKENALSSSSTADSKTKANRKITSYFTVVGQQAEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00512207;
90% Identity
iTF_00512207;
80% Identity
-