Basic Information

Insect: Drosophila kuntzei
Gene Symbol: Znf574
Assembly: GCA_035042165.1
Location: JAWNLU010001416.1:1048153-1050455[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.8 2e+02 2.9 2.6 2 23 323 345 322 345 0.94

2 10 0.06 4.5 8.1 0.1 6 23 355 372 355 372 0.98

3 10 0.0011 0.082 13.6 2.4 1 23 378 400 378 400 0.96

4 10 0.44 32 5.4 0.6 1 14 406 419 406 429 0.74

5 10 0.00023 0.017 15.7 1.3 1 23 437 460 437 460 0.97

6 10 0.16 12 6.8 0.4 3 23 468 489 466 489 0.92

7 10 0.51 38 5.2 0.2 2 23 501 523 500 523 0.93

8 10 0.0082 0.61 10.8 4.1 1 23 530 553 530 553 0.93

9 10 5.4e-07 4e-05 24.0 1.4 1 23 559 581 559 581 0.98

10 10 0.041 3.1 8.6 3.3 1 23 587 610 587 610 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.8	2e+02	2.9	2.6	2	23	323	345	322	345	0.94
2	10	0.06	4.5	8.1	0.1	6	23	355	372	355	372	0.98
3	10	0.0011	0.082	13.6	2.4	1	23	378	400	378	400	0.96
4	10	0.44	32	5.4	0.6	1	14	406	419	406	429	0.74
5	10	0.00023	0.017	15.7	1.3	1	23	437	460	437	460	0.97
6	10	0.16	12	6.8	0.4	3	23	468	489	466	489	0.92
7	10	0.51	38	5.2	0.2	2	23	501	523	500	523	0.93
8	10	0.0082	0.61	10.8	4.1	1	23	530	553	530	553	0.93
9	10	5.4e-07	4e-05	24.0	1.4	1	23	559	581	559	581	0.98
10	10	0.041	3.1	8.6	3.3	1	23	587	610	587	610	0.97

Sequence Information

Coding Sequence: ATGGATCTAACAGTGCCTGAGAGCTGCATACTCTGTCTGGAGGATAATCCGCTGACACTGGACCAACACATCGATATATATTCCACAAAAGGTGCACAGCTTAATGTGGTGAAGATTATCAACAAACATTTGCCAATGCAGCTGGCAGTGAGCAGTGAAGAAGCGCGTAAAATATGCCCGGAATGCTGGAAGACAATTTCCGCTTTCCATACGCTACATGATTTTGTCAGCGCTGCGCAGGTTTCGCTGCGGGAGACGAAACTGTTGCTCATGGATGAAGATGATCCGCTGACGCAGGGCAACTTCAATGAATCGACTGCTAAACAGTGTCCCGATCAAACGGAGCTATCATTCTACCCGGAGGTTAAGATTGAGGAGCACGAGCTCGAACAGTTGCCAAAAATTGAGGTGCTCGAGAGTACGACAAATCTGGATGCTTCTCCGGCAAGACGTTTACGGAAACGCGTCAAGGCAGAAGCTGAAACTGCAAATTGCCATGGCGAAATAAGTCCAGTTGTTATCACGGATGAAGCGGCGCCAAAAAAACGTCGCGGTCGACCACGTAAAACGGAAATTCCAAAGGAAACGCCTGTGGAGCAGCAAGTGACTAAATCCTTAGATTTAGAGTCCGATttgaaaacggaaaaacctACGGAATTTagcgacgatgatgatgatcaggAATTCAGTTGCAATTTCGATGAAGGTATCGATCGCAGCGATGACAGCAGTGAAGATTCCCCCGACAGCGATGATGATTCCGACTTTGAGTTCAAGGCAGAGAAGCCCAGCGAAGTGGCGTTTGCCGTGATACCAAAGCGAACTCCAGTGCGGCCCAAGAAATACAAGAAACGAGCGAAACCCGCCGAGCCAAAGGTGCGCATGTCTCGGGAATTGTTGGATCAGCGCAAGAAGCAGCAGGAGGAGTACGATGGGATTATTGCCAAGTTCTTTAGTGATGTGCTGCCATGCTCCATCTGCAATTTGTTGGTGCACAACTTTACGGAAATGCAACGCCATCATCGTCTCACACATCAGGTTGATCCCGGCTATATGATCTGCTGTGGTCGCAAATTCACCCAACGCAAGGTGCTCGCTGAACATGTGCTGGTTCACTGGAATCCCGAGCACTTCAAGTGCATCACCTGCGAGAAGGCATTCCAAAACTCACGGCATCTGGAGTCACATCAACAGGTGCATGTGGCAAAGGTTTCCTTTCAATGCGATCTATGCTCAAAGGTCTTTCTCAGCAAGACGGCCATTGACTATCATAAGCTAAACAAACATGTACCCAAATCCGAGTTCAAATTCACGTGCGCCGAATGCGGCAAAAAATTCCTGACTGAGCGTAAGCTGAAGAATCACATGAGTTCCATGCACGATCCGGAGAGTATAATTATTTGCGACAAATGTGGCAAACAGATGCGCACCAAGATCATTTTGAAGAAGCATCAGGAACTGATGCACTCGAACACACCGCGCCCGGAGCCCGAGTTGAAGCAGTGCCAAATCTGTGGGGCCTGGCTTAAGGGGATGACGGGACTGAAGCAGCACATGAAGAGCATTCATGTGGAGAGTGCGGGAGAGCATCGGTGTCATGTGTGCAGCAAGATTTCACCAAATGCTCGTGCTCTCCGACGACACATCTATCACAATCACGAATGCGAGCGTAAATTCAAGTGTACCATGTGCGATAAGGCTTTCAAGCGACCCCAGGAACTAAAGGAACATACATCCACACACACGGGCGAAGTGCTGTACACCTGTCCAAATTGTCCCATGACGTTCTTCTGCAGCGCCAACATGTACAAGCATCGACAGCGCTTGCATCGGGCCCAATATATGGCCGATAAGAATCAGCCAAAGCCTCCAAATATATTGCAGCAGGCGGTGGGAGCCACAGCGGCCATGAAGATCAAACTGATGCAAACCTCGAGCGCAGCTAGCATAGAATCCGACTTAAAGCATTTCTAG
Protein Sequence: MDLTVPESCILCLEDNPLTLDQHIDIYSTKGAQLNVVKIINKHLPMQLAVSSEEARKICPECWKTISAFHTLHDFVSAAQVSLRETKLLLMDEDDPLTQGNFNESTAKQCPDQTELSFYPEVKIEEHELEQLPKIEVLESTTNLDASPARRLRKRVKAEAETANCHGEISPVVITDEAAPKKRRGRPRKTEIPKETPVEQQVTKSLDLESDLKTEKPTEFSDDDDDQEFSCNFDEGIDRSDDSSEDSPDSDDDSDFEFKAEKPSEVAFAVIPKRTPVRPKKYKKRAKPAEPKVRMSRELLDQRKKQQEEYDGIIAKFFSDVLPCSICNLLVHNFTEMQRHHRLTHQVDPGYMICCGRKFTQRKVLAEHVLVHWNPEHFKCITCEKAFQNSRHLESHQQVHVAKVSFQCDLCSKVFLSKTAIDYHKLNKHVPKSEFKFTCAECGKKFLTERKLKNHMSSMHDPESIIICDKCGKQMRTKIILKKHQELMHSNTPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHVCSKISPNARALRRHIYHNHECERKFKCTMCDKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYMADKNQPKPPNILQQAVGATAAMKIKLMQTSSAASIESDLKHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586244;
90% Identity: iTF_00586244; iTF_00585510; iTF_00602121; iTF_00534127;
80% Identity: -