Basic Information

Insect: Drosophila kuntzei
Gene Symbol: ken1
Assembly: GCA_035042165.1
Location: JAWNLU010001282.1:245390-247822[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.071 5.3 7.9 5.9 3 23 263 283 261 283 0.96

2 12 0.00095 0.071 13.8 0.5 1 23 289 314 289 314 0.94

3 12 0.002 0.15 12.7 1.2 1 23 321 346 321 346 0.93

4 12 0.0017 0.13 13.0 4.1 1 23 356 378 356 378 0.96

5 12 0.002 0.15 12.8 2.2 1 23 385 407 385 407 0.97

6 12 0.0077 0.57 10.9 0.5 1 23 413 435 413 435 0.97

7 12 0.056 4.2 8.2 2.6 1 23 441 464 441 464 0.97

8 12 0.02 1.5 9.6 4.1 1 23 470 492 470 492 0.95

9 12 0.023 1.7 9.4 2.6 2 23 499 520 498 520 0.95

10 12 0.0002 0.015 15.9 0.8 1 23 613 636 613 636 0.95

11 12 0.00039 0.029 15.0 0.8 1 23 642 664 642 664 0.95

12 12 1e-05 0.00078 19.9 2.3 1 23 670 692 670 692 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.071	5.3	7.9	5.9	3	23	263	283	261	283	0.96
2	12	0.00095	0.071	13.8	0.5	1	23	289	314	289	314	0.94
3	12	0.002	0.15	12.7	1.2	1	23	321	346	321	346	0.93
4	12	0.0017	0.13	13.0	4.1	1	23	356	378	356	378	0.96
5	12	0.002	0.15	12.8	2.2	1	23	385	407	385	407	0.97
6	12	0.0077	0.57	10.9	0.5	1	23	413	435	413	435	0.97
7	12	0.056	4.2	8.2	2.6	1	23	441	464	441	464	0.97
8	12	0.02	1.5	9.6	4.1	1	23	470	492	470	492	0.95
9	12	0.023	1.7	9.4	2.6	2	23	499	520	498	520	0.95
10	12	0.0002	0.015	15.9	0.8	1	23	613	636	613	636	0.95
11	12	0.00039	0.029	15.0	0.8	1	23	642	664	642	664	0.95
12	12	1e-05	0.00078	19.9	2.3	1	23	670	692	670	692	0.98

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTGAATACTCCATACACTCGATATGCCGCATTTGCTTGAACCACCTGCGCAACGATGCGGTGTACGATCTGTTCCTGGTGCCAGGTCTGGCCAAGAAATTGTGTGTCTGCACTTCGCTCGCTGTGGAACAACACGATGGATTCCCGAAGAACCTTTGCACCAACTGCTACACGAAGCTGAACGATCTGCATGGATTCCAGAAGATGTGTGTGGACTCGGTGCAGAAGTTTCAGGATATGGTGGCCAATAATTATTTCACGCCCGTCATTTCCGATATCAATCAAATTGACAATGTTGATGTGCTGAATATTGCGCCACCCGAGGGAGAAATGGAAGAAGATCGCATTAATTTTGATCCGCTGTTGAATACGAAAATCGAGGTCATTGAGAATGAAGAtgatgtatttaaaatgcttGAAGATGTCGACAAAGAAGTTGAGGATGTGGACAAGGATGGCGAATCATCCTCGGAGAGCGAAGAGTACAATGATCAGGATGCCGATGGAGACAGAGATGATGACTTTGAGGTGAACAGCAGTGAATCCGATGATGCGATGCCATTGTCACGTCTGCGTGGTGCAACCAGAGCATCCAAAGCCAAGGCCCGAAAAACGACCAAACGGAAtgttaataatgatgatgacgataatTCCTCCAGCTCTGAATCgaatgacgatgatgatgacgacgatgatgatgacgatagACCCAGATCGAAACCAAAACGCAAGCGTATTCCGGCTGCCGATCGTGATCGTCATCGTCTCATCGATTGTCACATTTGTCATCAGAAATTCAAGAAGGCCATACGCTACGAGGAGCACATGAAGCATCACAATGATCTGCTGCCATTCCAGTGCACGGTGGAGAGCTGCAAGAAGGGTTTCACCACCGCCGGCGGTCTGCGTCTGCACATGGATCATGCCCACATTGAATTCTCCGAGGTGCACGCCTGCACCTTTGAGGGATGCGATAAGACATTCCCCCGCTCTGTCTTGCTCACGTTCCACATGAAGAAGGTGCACAAGGTGGCCAAGCCGGATGTCAAAAAGCATGCCTGCACCGAATGTGAGAAAGTTTTCCGCTGTCCAACCGCACTCAAGAAGCACATGTATAAACACACTGGGGAGGAGCTGCCATTTGCCTGTGAGATCTGCGGCAAACGATTCCACATTCACAGCGTGCTCCGGGATCATCTGTTGCGTCATGCCGGCGTCAAGAATCATGTGTGTCCGTATTGTGGAGTGGGCAAAACAACCCGGCAGGAGTGGAACAAACACATCTTGACGCACACCAGGGAGAAACAGTTCCAATGCCGTCAATGCGATCATGCCTCCCACAACAAACAGGCGCTGTCTAATCATGTTAAGGTGGTGCACATGAAGATCAAGAACTTTGCCTGCCAATATTGTGGCAAGACATTTGGCAAATCCCATGCCTGCAAGATCCACGAGAGATTGCACACGGGAGAGAACTGCTGCGAGTGCAAGATCTGTGGCAAGATTTTCCTCTTCGAGAAGAGATTGACGAAGCATCTGCAGTTGCATGAGAAGCGTGATATACCGCCAGCTGAAACCGCTGTGAAACCCCAAGATGCTGGACAGAGCACTCCGGGTGTCAGCCAGGATCCGAGTCAGCAGAGTCATCTGACAGAGCCTGTGGATGTGAAACCACTGCCAGTTGTTCCCCCCAAGCCGAAGAACTCACATCGTGTGGAGCGCGTGGACATCTCCCAGCTGGCAGGCACCTCGGTTAATCCAATATCATCTGTATCCGTTCCCTCCTGGTCGCCACAGGTCAACTTCACCAAGAAGGAAGGCCAACACATCTGTCCAGGCTGTGGACGTGGCTTCAATCACATTGGCAACATGAAACTCCACTACAAGATTATACACGAGAAGGTCAAGGATTTCGCCTGTCGCTATTGTCCCAAGCGGTTTGCCAAGGCGCAATATCTGCGTAATCATGAGTATATACATACGGGTGAGAAGCCCTTCGAGTGCAAGATCTGTGGCAAGCATTTCCGCCAGGAGCAGGTGTTGAAGACGCATCTCAAGGTGCACGACAAGCCGCCAAAGCAGCCCAAGGAGAAGAAGCCGCCGAAACCGTCAGTTAGCAAAGCCAGAGGATTGAAAGTGGAGCTCAACAAAAAGCAACCAAAGATTCATGACGAATATCAGGATCCAGCGGCGGAACGGGCTGCAGCGACGGCCGCTCTCCTGGCTCAACAGATCGAGGAGAATGAGGCGAAGCGGAAGCAGGAGGAGGCAAATCGTAAGATTCAGGAGGCCGCCTGTGAGCAGCTCAATAGACTTCAAAAGCAAATCCAGAGCGAAAAAGGATCCTACGACAGCTACTATGGACAGAAAACGGAAGCCGAGGGCATGAATCCCGATGTTCTCAAATTAGATCATgtttaa
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDAVYDLFLVPGLAKKLCVCTSLAVEQHDGFPKNLCTNCYTKLNDLHGFQKMCVDSVQKFQDMVANNYFTPVISDINQIDNVDVLNIAPPEGEMEEDRINFDPLLNTKIEVIENEDDVFKMLEDVDKEVEDVDKDGESSSESEEYNDQDADGDRDDDFEVNSSESDDAMPLSRLRGATRASKAKARKTTKRNVNNDDDDNSSSSESNDDDDDDDDDDDRPRSKPKRKRIPAADRDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCKKGFTTAGGLRLHMDHAHIEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKPDVKKHACTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQLHEKRDIPPAETAVKPQDAGQSTPGVSQDPSQQSHLTEPVDVKPLPVVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKQPKEKKPPKPSVSKARGLKVELNKKQPKIHDEYQDPAAERAAATAALLAQQIEENEAKRKQEEANRKIQEAACEQLNRLQKQIQSEKGSYDSYYGQKTEAEGMNPDVLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00608675;
80% Identity: -