Dkun008545.1
Basic Information
- Insect
- Drosophila kuntzei
- Gene Symbol
- -
- Assembly
- GCA_035042165.1
- Location
- JAWNLU010001282.1:249164-251704[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.074 5.5 7.8 5.9 3 23 251 271 249 271 0.96 2 12 0.0037 0.28 11.9 0.5 1 23 277 302 277 302 0.92 3 12 0.0025 0.19 12.4 1.1 1 23 309 334 309 334 0.96 4 12 0.00078 0.058 14.0 2.1 1 23 346 368 346 368 0.98 5 12 2.5e-06 0.00019 21.9 0.2 1 23 375 397 375 397 0.98 6 12 0.0072 0.54 11.0 0.1 1 23 403 425 403 425 0.98 7 12 0.007 0.52 11.0 4.0 1 23 431 454 431 454 0.98 8 12 0.0096 0.71 10.6 3.9 1 23 460 482 460 482 0.96 9 12 0.00016 0.012 16.2 3.6 2 23 489 510 488 510 0.96 10 12 4.3e-05 0.0032 18.0 0.3 1 23 619 642 619 642 0.96 11 12 0.011 0.84 10.4 1.2 1 19 648 666 648 670 0.94 12 12 1.9e-06 0.00014 22.3 4.1 1 23 676 698 676 698 0.99
Sequence Information
- Coding Sequence
- atgaatgaagGGAGTGAATACTCCATACACACGATATGCCGGATCTGCTTGAATCACCTGCGCAACGATGCCGCCTACGATCTGTTCCTGGTGCCAGGTCTGGCCAAGAAATTGTGTGTCTGCACTTCGCTCGCTGTGGAACAACAGGATGGATTCCCCATGAATCTCTGCACCAATTGCTTCAGCCGGCTTAATGACTTGCACGACTTTCAGAAGCTGTGCGTGGACTCAGTGCAGAGATTTCAGGAGATGGTCGCCAAAAATTTCTTTACACCTGCGGCGGcacaaatcaatcaaattgataattttgatgAACTAAATGTGGCGTCACAGGAGGGCGACTTGGcgggggaggaggaggatcGCATTAATTATGATCCATTGCTGAATCACAAAATGGAAATCATTGAGAATGAGGAGGATGTATTCAAAATGCTGGAACATGTGGACAAAGAGGCTGAAGAGGCGGAGAACGAGGTTAAACAGGATGTTGAGGATCTAGACGATGATTCCATCTTTGACAGCAGCAACGACATGGACAATGATGTGGACTTCGAACCCAATAGCAGCGATGGAGATGATGATATGCCGTTGGCCCAACGCTTGCGAGTAACTCCCAGAACGAGCTCAAAGAAAATATCCGCGGATGATGAAGACTTTAGTTCGGGATCCGACGAAGACGGGGTCAAATCCAAGTCGAAACGGAAGCGTATTCCGGCAGCTGAGCGTCATCTGCATCGCATCATCGATTGTCACATTTGTCATCAGAAATTCAAGAAGGCCATACGCTACGAGGAGCACATGAAGCATCACAATGATCTGCTGCCATTCCAGTGTAAGGTGGAGACCTGTCGCAAGGGTTTCACCACCGCCGGCGGCTTGAGACTGCATGTGGATCATGCGCACACGGAACTGTCCGAGGTGCACACGTGCAGCGTTGAGGGATGCGGCAAGACCTTCCCGCGCATCCGTCTGCTCACGTTCCACATGAAGAAGGTGCACAACATCTCCAAGGCGGCGGCGCCGCCCAGAGATTATCCCTGCACCGAGTGTGAGAAGATCTTCCGCTGTCCCATGGCGCTGAAGAAGCACATGTATAAGCACGATGGCAAGGAGCTGCCCTTCCCCTGCAATATCTGTGGCAAGCGCTTTGTCATCAACAGTGCGCTCAAGGATCATCTAATGCGGCATGCGGGGATTAAGAACTATGTGTGTCCGTATTGTGGTGTGGGCAAAACAACCAGGCAGGAGTGGAACACACACATCCTGACGCACACGCAGGAGAAGAAGTTCAAGTGTCATATATGCGAGCATGCCTCCCACAACAAACAGAGTCTGGCCAATCACATCAAGATCGTGCACGAGAAGATTAAGAACTATGCATGTCAATATTGTGGCAAGACCTTTGGCAAATCCCATGCCTGCAAGATCCATGAGATGACGCACACGGGGGAGAAACGTTGCGAGTGCAAGGTCTGTGGCAAGAAGTTCCTCTATCCAAAGAGTCTAACGAAGCATCTGAAGACGCACGAGAAGCGTGTGCTGCGTGCCATTGAAACGTATCGTCAGCGTCAGGTGGAACTGGGCGAGGGAGCTGCAACGGAGCCAACGGATATTGCAACTGTTCCAGCACCGTCCACAACAGCGGAAGGAGTCGACGTCATCATGTCCCAAAATGCTGCCGATGAGTTGTTGAAAGTATGCGCCGAATCGGTGGCCACCATACCCAAGGATCCGCGTCGTGTGCAGCGGGTGGACATCTCCCAGCTGGCTGGCACCGCTGTCAATCCCATACCATCGGTATCCGTTCCCTCCTGGTCGCCACAAGTCAACTTCACCAAGAAGGAAGGCAAGCACATTTGTCCTGGTTGCGGTCAAGGCTTCAATAACATTGGCAACATGAAACGCCACTACAAGATTATACACGAGAAGGTCAAGGATTTCGCCTGTCGCTTCTGTCCAAAGCGCTTTGCCAAGGCACAAACACTGCGTCACCACGAATGGATTCATACGGGGGAGAAGCCCTTCGAGTGCAAGACTTGTGGCACACATTTCCGGCAGGAGACGGCGCTGAAGCGTCACCAGAGAACGCACGAGAATCGTCCGCCTGTCATCTCATCAAAATTCTATGCCGCCCGTGAGGAATTGGAGGAGCAGGAGCGCACAAAACGCGAGGCGAGACGCAAGGCGGAGGCGAAACGCAAGGAGATTGCCGAGGCAGCCAAGGAGCAGCTCTCGTCGCTGCACAAAATTGAGGCAACCGATAAGAATCTTCACTCGTATGATGAATACCAGGAGGCAGCGGCGGAACGAGCCGCGGCATCCGCTGAACTTCAGGCCCAGCAGTTCGAGGAGAACGAGGTGAAGCGGCGGGCGGACATGGAGCGTCGCAAGATCCAAGAAGCCGCCTACGAGCAGCTCCAGaaattgcagcaacagcaggagaTCGAGAAGGCACAAAGCTCCTACGATGGTTACTATGCCCAGAAGGCGCATGCCGATGGCACCACATTGGATGACCTAAAGATCGACCATGTTTGA
- Protein Sequence
- MNEGSEYSIHTICRICLNHLRNDAAYDLFLVPGLAKKLCVCTSLAVEQQDGFPMNLCTNCFSRLNDLHDFQKLCVDSVQRFQEMVAKNFFTPAAAQINQIDNFDELNVASQEGDLAGEEEDRINYDPLLNHKMEIIENEEDVFKMLEHVDKEAEEAENEVKQDVEDLDDDSIFDSSNDMDNDVDFEPNSSDGDDDMPLAQRLRVTPRTSSKKISADDEDFSSGSDEDGVKSKSKRKRIPAAERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCRKGFTTAGGLRLHVDHAHTELSEVHTCSVEGCGKTFPRIRLLTFHMKKVHNISKAAAPPRDYPCTECEKIFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVELGEGAATEPTDIATVPAPSTTAEGVDVIMSQNAADELLKVCAESVATIPKDPRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISSKFYAAREELEEQERTKREARRKAEAKRKEIAEAAKEQLSSLHKIEATDKNLHSYDEYQEAAAERAAASAELQAQQFEENEVKRRADMERRKIQEAAYEQLQKLQQQQEIEKAQSSYDGYYAQKAHADGTTLDDLKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575777;
- 90% Identity
- iTF_00537678;
- 80% Identity
- -