Basic Information

Insect: Drosophila kuntzei
Gene Symbol: -
Assembly: GCA_035042165.1
Location: JAWNLU010001282.1:239692-241911[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.003 0.22 12.2 6.3 2 23 226 247 225 247 0.97

2 12 0.00036 0.027 15.1 4.4 1 23 253 278 253 278 0.95

3 12 0.00026 0.019 15.5 0.8 1 23 285 310 285 310 0.95

4 12 0.00015 0.011 16.3 2.2 1 23 318 340 318 340 0.96

5 12 0.00029 0.022 15.4 0.8 3 23 349 369 347 369 0.98

6 12 0.00011 0.0083 16.7 0.1 1 23 375 397 375 397 0.98

7 12 0.17 13 6.7 7.6 1 23 403 426 403 426 0.98

8 12 0.0086 0.64 10.8 2.0 1 23 432 454 432 454 0.95

9 12 0.00022 0.016 15.8 2.3 1 23 460 482 460 482 0.98

10 12 2.7e-05 0.002 18.6 0.3 1 23 564 587 564 587 0.97

11 12 0.0024 0.17 12.5 5.9 1 23 593 615 593 615 0.96

12 12 6.7e-06 0.00049 20.5 2.4 1 23 621 643 621 643 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.003	0.22	12.2	6.3	2	23	226	247	225	247	0.97
2	12	0.00036	0.027	15.1	4.4	1	23	253	278	253	278	0.95
3	12	0.00026	0.019	15.5	0.8	1	23	285	310	285	310	0.95
4	12	0.00015	0.011	16.3	2.2	1	23	318	340	318	340	0.96
5	12	0.00029	0.022	15.4	0.8	3	23	349	369	347	369	0.98
6	12	0.00011	0.0083	16.7	0.1	1	23	375	397	375	397	0.98
7	12	0.17	13	6.7	7.6	1	23	403	426	403	426	0.98
8	12	0.0086	0.64	10.8	2.0	1	23	432	454	432	454	0.95
9	12	0.00022	0.016	15.8	2.3	1	23	460	482	460	482	0.98
10	12	2.7e-05	0.002	18.6	0.3	1	23	564	587	564	587	0.97
11	12	0.0024	0.17	12.5	5.9	1	23	593	615	593	615	0.96
12	12	6.7e-06	0.00049	20.5	2.4	1	23	621	643	621	643	0.98

Sequence Information

Coding Sequence: ATGAGTGAGGAGACGCCACCCTCAATGCATACAATATGCCGCACTTGTCTGTCCACATTGCAACGCGCTGAAGCCTTCGACCTGTTTGGTGTTCCGGGCCTGGCCAAgaagttgtgtgtgtgcacttcCCTCTCAGTGGAGCACCTGGATGGATTCCCAAGAAACATCTGCACCACCTGCCACAGCCGCCTAAACGATCTACATGACTTTCAAAAGCAATGCGTGGATTCTGTGCAAAGATTTAAGGAGTTGGTGTCCAGAAACTGCTTCATAATCCGGGATATTCCAGAGGACGATCCTGCCGTCGTAAATGCTTCGGGGCAGGATGTTGTCCATGAAGAGGAACATATTAACTTCGATCCCCTTTTGAacacaaaaatagaaattgataATGAGGaggatgtttttaaaatgattgaaGATGTCGATAAGGAATCTGAGAATGACGAGAACTGGAAGGATGCATTTAATGACAGCGGGAGCGAGTTTAACAATGAGGATGTGGGATTACAAGAAGACAGCAGCGATTCCGATGATGAAATGCCGCTGTCCCGTCTTCGAAGTAACACCAGAGCCACAAAGTCCAAGACCAAAAAGGATGATAAGGAAAAGTCCAAAGAGAAACCGAAACGTAAGCGTATTCCAGCAGCTGAGAGACATTTGCACCGCACCATTGAATGTCATATTTGTAATCAGAATTTTAAGAAGGCGTCGTGCTATGAGGAGCATATGAAACATCACAATGACCAATTACCATTTCAGTGTTCAGTGGAGAAGTGTAAGAAGGGTTTCACAACATCCACAGGACTCAAGCATCATATGGAGCACACGCACACGGAACTATGTGATCGTCACCCTTGTAAAGTCGAAGGATGCAATGAATCCTTTGCACAAACTCGGATGCTCACACAACATCTGAGAAAGGTGCATAATATTGCCAAGCCCATAATACATCCATGCCCGGAATGCGATAAAGTATTCCGTTGTCCAATGGCACTGAAGAAACACATGTATAATCACACTGGGGAGGAGCTGCCCTTCGGCTGTAACATCTGCCAGAAACGCTATCGAGTGAATACCGAACTCCGAGATCATCTTTTACGCCACGCCGGGATCAAAAACTTTGTATGCCCTTATTGCGGTGTGGGCAGAACCACAAAACAGGAGTTGGACAAGCACATACTGACGCACACGAAGGAGAAGAAGTTCAAGTGTGATCAGTGCGATCATACTTCCCACAACAAGCAATGTATGACCAAGCACATCAAGGTGGTTCACATGAAGATCAGGAACTTTGTCTGTCAGTACTGTCCAAAATCCTTTGGGAGTGCGTATGGCTGTAAGAACCATGAGAAACTACATACTCGGAATGATTGTTTCGAGTGCACAATCTGTGGAAAGAAATTCCTCTTCGAGAAGAGATTAACAAAGCATTTGAGGACTCATGAGAAGCGCAAAAATAAATCAGATACGAGCTCGAAAAAGACGGAAACTGTTGGGGATATCCAGGAGACAATAAAACCAATAGCCGTAATTAAAAAACCAGATATTCCAGTTAAGCCAAGGGATCCACGTCGAGTTGAGGTAGTGGATATATCTCAACTTGCTGGCACTGCTGTTAATCCCTTTCCCTCGGTATCAGTATCATCTTGGTCCCCGCATGAGGACTTTCCCAAAAACGAAGGCCAGCACGTTTGTCCGGAGTGTGgcaaaaactttaataaaattgctgGCTTGAAGCTCCACGTTAAGACTGTACACGATAAGATCAAGGACTTTGCCTGTCGCTTCTGTCCCAAACGATTTGGGAAATCAAGCCACCTCCGTCATCATGAATATACACATACGGGGGAAAAGCCGTACGTTTGTAAAGTATGCAATCAAACTTTCAGGCATGATGGAACATTAAGAAGGCATATGGAATCACACAACAGACCTCCAAGGGAACCGAAGGATCCGAAGAAAACTAAGCCCGTGTCAAAAGATCCTCAGGAACCTAGACTGAAGCTAAATATGGAACCAGTCAAGAATTACGAGCAGTATCAAGATCCAGATGCGGAACGAGCCGCTGCAACAGCTCAATTGATGGCCCAACAACTGGAAGAAAGTGAGGCAAAGCGTAGGGCGGAAGCAAAAACCCGGGAAATTCAAGAGGCAGCGTGTAAGCAGCTCCAGAAATTGCAGCAGCCGCAGAGTTCCTATGATAGCCCCACTGAATAA
Protein Sequence: MSEETPPSMHTICRTCLSTLQRAEAFDLFGVPGLAKKLCVCTSLSVEHLDGFPRNICTTCHSRLNDLHDFQKQCVDSVQRFKELVSRNCFIIRDIPEDDPAVVNASGQDVVHEEEHINFDPLLNTKIEIDNEEDVFKMIEDVDKESENDENWKDAFNDSGSEFNNEDVGLQEDSSDSDDEMPLSRLRSNTRATKSKTKKDDKEKSKEKPKRKRIPAAERHLHRTIECHICNQNFKKASCYEEHMKHHNDQLPFQCSVEKCKKGFTTSTGLKHHMEHTHTELCDRHPCKVEGCNESFAQTRMLTQHLRKVHNIAKPIIHPCPECDKVFRCPMALKKHMYNHTGEELPFGCNICQKRYRVNTELRDHLLRHAGIKNFVCPYCGVGRTTKQELDKHILTHTKEKKFKCDQCDHTSHNKQCMTKHIKVVHMKIRNFVCQYCPKSFGSAYGCKNHEKLHTRNDCFECTICGKKFLFEKRLTKHLRTHEKRKNKSDTSSKKTETVGDIQETIKPIAVIKKPDIPVKPRDPRRVEVVDISQLAGTAVNPFPSVSVSSWSPHEDFPKNEGQHVCPECGKNFNKIAGLKLHVKTVHDKIKDFACRFCPKRFGKSSHLRHHEYTHTGEKPYVCKVCNQTFRHDGTLRRHMESHNRPPREPKDPKKTKPVSKDPQEPRLKLNMEPVKNYEQYQDPDAERAAATAQLMAQQLEESEAKRRAEAKTREIQEAACKQLQKLQQPQSSYDSPTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586113;
90% Identity: iTF_00523127;
80% Identity: -