Basic Information

Insect: Drosophila kuntzei
Gene Symbol: -
Assembly: GCA_035042165.1
Location: JAWNLU010001282.1:242499-244754[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0043 0.32 11.7 4.5 2 23 223 244 222 244 0.97

2 12 0.00073 0.054 14.1 3.4 1 23 250 275 250 275 0.95

3 12 0.00032 0.023 15.3 0.6 1 23 282 307 282 307 0.95

4 12 0.0017 0.13 13.0 3.5 1 23 315 337 315 337 0.97

5 12 7.3e-05 0.0054 17.3 0.9 3 23 346 366 344 366 0.98

6 12 0.00011 0.0085 16.7 0.1 1 23 372 394 372 394 0.98

7 12 0.17 13 6.6 7.6 1 23 400 423 400 423 0.98

8 12 0.035 2.6 8.8 5.7 1 23 429 451 429 451 0.94

9 12 0.00011 0.0082 16.7 2.1 1 23 457 479 457 479 0.99

10 12 8.4e-06 0.00062 20.2 0.4 2 23 557 579 556 579 0.96

11 12 0.0004 0.03 15.0 4.7 1 23 585 607 585 607 0.96

12 12 3.5e-05 0.0026 18.3 2.2 1 23 613 635 613 635 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0043	0.32	11.7	4.5	2	23	223	244	222	244	0.97
2	12	0.00073	0.054	14.1	3.4	1	23	250	275	250	275	0.95
3	12	0.00032	0.023	15.3	0.6	1	23	282	307	282	307	0.95
4	12	0.0017	0.13	13.0	3.5	1	23	315	337	315	337	0.97
5	12	7.3e-05	0.0054	17.3	0.9	3	23	346	366	344	366	0.98
6	12	0.00011	0.0085	16.7	0.1	1	23	372	394	372	394	0.98
7	12	0.17	13	6.6	7.6	1	23	400	423	400	423	0.98
8	12	0.035	2.6	8.8	5.7	1	23	429	451	429	451	0.94
9	12	0.00011	0.0082	16.7	2.1	1	23	457	479	457	479	0.99
10	12	8.4e-06	0.00062	20.2	0.4	2	23	557	579	556	579	0.96
11	12	0.0004	0.03	15.0	4.7	1	23	585	607	585	607	0.96
12	12	3.5e-05	0.0026	18.3	2.2	1	23	613	635	613	635	0.98

Sequence Information

Coding Sequence: ATGAATGAGGAGAATCCACGGTCAATACATACAGTATGCCGCACTTGTTTGTCCAACTTGCAACAAGATGAAGCCTTCGACCTGTTTGGTGTTCCGGGCCTGGCCAAgaagttgtgtgtgtgcacttcCCTCTCAGTGGAGCACCTGGATGGATTCCCGAGAAACCTCTGCGCCACCTGCCACAGCCGCCTGAACGATCTACATGACTTTCAAAAACAATGCGTGGAGTCTGTGCAAAAGTTCAAGGATCTAATATCCAACACCTGCTTCACAATCCGGACAATTCCGGAGGACGATCCTCCTTTCGTAGATGCTGTTGTGCACAATGTTGAGGAACACATTAATTTTGACCCACTGTTGAATacaaaaatggaaatagaCAATGAGGAGgatgttttcaaaatgattgaaAATGTCGATAAAGAATCCGAGGATGCCGACAATTTAGAGGATGCATTTAATGACAGCGGAAGCGACTTTAACAATGAGGATGTGGACTTCCAAGTGGATAGCAGCGATTCCGATGATGAGATGCCGTTGTCACGCCTGCGAAGTAACACCAGAGCCACAAAGTCCAAGTCCCGTAAGGATGATACAGACAAGCCCAAAGAGAAACCAAAACGTAAGCGTATTCCAGCAGCTGAGCGTGAGCTTCATCGGTTAATCGAGTGTCACATTTGTCGTCAGAAGTTCAAGAAAGCAGTGTGTTACGAGGAGCATATGAAACGCCACAATGATTTATTGCCATTTCAGTGTACGGCGAAAAATTGCCAAAGGGGTTTTACGACGTCCACAGGACTGAAGCATCATATGGAGCACGCGCACACGGAACTATGCGATCTTCATCCGTGCACTGTTGAAGGATGCAACGAATCATTTGCACAAACTCGGATGCTCACACAACATCTGAGAAAGGTGCATAATATTGCCAAGCCGGAAATCCATCCATGTTCGGAGTGTGAAAAAGTATTCCGTTGTCCAATGGCGCTCAAGAAACACATGTATAAACACACTGGGGAGGAGCTGCCCTTCGGCTGTAACATCTGCCAGAAACGATTTCGGGTCAATACTGAGCTCCGAGATCATCTTTTGCGACATGCCGGAATCAGAAACTTTGTTTGTCCTTATTGCGGTGTGGGCAGAACCACAAAACAGGAGTTGGACAAGCACATACTGACGCACACGAAGGAGAAGAAGTTCAAGTGTGATCAGTGCGATCATACTTCCCATAATAAACAATGTATGACCAAGCACATCAAGGTGGTGCACATGAAGATCAGGGACTATTTATGTCAGTATTGCCAAAAGTCATTTGCCAGCGCTTATCACTGCAAGAACCACGAGAAACTACATACTCGGAATGATTGTTTCGAGTGCAAAATCTGTGGCAGGAAATTCCTTTTTGAGAGTAGATTAACAAAGCATTTAAGGACGCACGCCAAGCACGGTAGTAAATCTGCAGCAAGCTCGGCAAAGACGGAAACTGATTTGGATGTACAGACGGAAGCTGTGAAAGTACCAGAAATTCCAGTCAAACCAAGGGATCCGCGTCGAATTGAGATTGTGGATATATCTCAATTGGCTGGGACCATCGTTAATCCCATTCCATCGGTGTCTGTATCATCCTGGTCGCCGCAAGAGACCTTCACCAAAAACGAAGGACAGATCGTTTGTCCAGACTGTGGCCGAGGCTTCAACCATCTCAGCAATATGAAGCTCCACTACAAGGTTGTACACGAAAAGATCAAGGACTATGCCTGTCGCTTTTGTCCCAAGCGCTTTAGCAGATCTCAATATCTCCGCCATCATGAGTATACACATACGGGTGAGAAGCCCTACGAGTGCAAGATATGCAATCAACGCTTTAGGCATGATGCAACATTGGGCAGGCATATGCAATCGCACAACCGACCTCCAAAGGATCCAAAGAATCCTAAGCGCAGGAAAAAGGATCCTCAGGAGCCGAGATTAACACTCAATACGGAGCCAATAATGAATTACGAACAGTACCAAGATCCAGATGCCGAGCGGGAGGCAGCAGCGGCCGAGTTGGTGGCCCAACAGCTCAACCGCGAGGACGGTGACGGCAAACCCAAGTGGGGACTGGCCAAAGGTGGCGAGATTCAAGAGGCAGCTTGTGAGCAGCTCCTAAAGTTGCGGCAAAAGCAACTAGAAAAGATTTCCTATGATAGCTTCGCTGACCAAGTCTCCGAATCTTCTGGTATTCGCAAGGATATACTCAAAAATCATGTATAA
Protein Sequence: MNEENPRSIHTVCRTCLSNLQQDEAFDLFGVPGLAKKLCVCTSLSVEHLDGFPRNLCATCHSRLNDLHDFQKQCVESVQKFKDLISNTCFTIRTIPEDDPPFVDAVVHNVEEHINFDPLLNTKMEIDNEEDVFKMIENVDKESEDADNLEDAFNDSGSDFNNEDVDFQVDSSDSDDEMPLSRLRSNTRATKSKSRKDDTDKPKEKPKRKRIPAAERELHRLIECHICRQKFKKAVCYEEHMKRHNDLLPFQCTAKNCQRGFTTSTGLKHHMEHAHTELCDLHPCTVEGCNESFAQTRMLTQHLRKVHNIAKPEIHPCSECEKVFRCPMALKKHMYKHTGEELPFGCNICQKRFRVNTELRDHLLRHAGIRNFVCPYCGVGRTTKQELDKHILTHTKEKKFKCDQCDHTSHNKQCMTKHIKVVHMKIRDYLCQYCQKSFASAYHCKNHEKLHTRNDCFECKICGRKFLFESRLTKHLRTHAKHGSKSAASSAKTETDLDVQTEAVKVPEIPVKPRDPRRIEIVDISQLAGTIVNPIPSVSVSSWSPQETFTKNEGQIVCPDCGRGFNHLSNMKLHYKVVHEKIKDYACRFCPKRFSRSQYLRHHEYTHTGEKPYECKICNQRFRHDATLGRHMQSHNRPPKDPKNPKRRKKDPQEPRLTLNTEPIMNYEQYQDPDAEREAAAAELVAQQLNREDGDGKPKWGLAKGGEIQEAACEQLLKLRQKQLEKISYDSFADQVSESSGIRKDILKNHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00585379;
90% Identity: iTF_00575779;
80% Identity: -