Basic Information

Insect: Drosophila kuntzei
Gene Symbol: VEZF1
Assembly: GCA_035042165.1
Location: JAWNLU010001684.1:2787928-2792538[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0018 0.14 12.9 2.0 1 23 209 231 209 231 0.96

2 26 0.071 5.3 7.9 1.5 1 23 237 259 237 259 0.97

3 26 0.47 35 5.3 0.9 2 23 291 312 290 312 0.96

4 26 0.0016 0.12 13.0 3.6 1 23 387 410 387 410 0.94

5 26 3 2.2e+02 2.8 4.2 2 23 422 445 421 445 0.93

6 26 0.18 13 6.6 2.6 1 23 451 473 451 473 0.97

7 26 0.071 5.2 7.9 0.3 2 23 492 513 491 513 0.96

8 26 0.0038 0.28 11.9 1.5 1 23 588 611 588 611 0.96

9 26 0.029 2.2 9.1 0.1 1 22 620 641 620 641 0.95

10 26 1.3 97 3.9 7.5 1 23 650 672 650 673 0.93

11 26 0.0002 0.015 15.9 0.3 2 23 704 725 703 725 0.97

12 26 5.9e-06 0.00044 20.7 3.5 1 23 733 755 733 755 0.99

13 26 0.061 4.5 8.1 1.5 1 23 905 928 905 928 0.95

14 26 0.015 1.1 10.0 2.2 1 22 935 956 935 956 0.94

15 26 0.091 6.7 7.5 0.5 1 23 965 988 965 988 0.91

16 26 1.2e-05 0.00089 19.7 1.8 1 23 1013 1035 1013 1035 0.97

17 26 0.00014 0.011 16.4 0.9 1 23 1042 1064 1042 1064 0.98

18 26 0.0085 0.63 10.8 0.0 2 20 1091 1109 1090 1111 0.93

19 26 0.011 0.84 10.4 4.7 1 23 1156 1179 1156 1179 0.96

20 26 0.02 1.5 9.6 0.4 1 23 1216 1239 1216 1239 0.96

21 26 0.00099 0.073 13.7 3.5 1 23 1261 1284 1261 1284 0.97

22 26 1.4e-05 0.001 19.5 0.1 2 23 1312 1333 1311 1333 0.95

23 26 4.7e-05 0.0035 17.9 2.9 1 23 1339 1361 1339 1361 0.99

24 26 2.3e-06 0.00017 22.0 2.0 1 23 1367 1389 1367 1389 0.97

25 26 5.9e-08 4.4e-06 27.0 2.4 1 23 1395 1417 1395 1417 0.99

26 26 0.00073 0.054 14.1 0.3 1 22 1423 1444 1423 1447 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0018	0.14	12.9	2.0	1	23	209	231	209	231	0.96
2	26	0.071	5.3	7.9	1.5	1	23	237	259	237	259	0.97
3	26	0.47	35	5.3	0.9	2	23	291	312	290	312	0.96
4	26	0.0016	0.12	13.0	3.6	1	23	387	410	387	410	0.94
5	26	3	2.2e+02	2.8	4.2	2	23	422	445	421	445	0.93
6	26	0.18	13	6.6	2.6	1	23	451	473	451	473	0.97
7	26	0.071	5.2	7.9	0.3	2	23	492	513	491	513	0.96
8	26	0.0038	0.28	11.9	1.5	1	23	588	611	588	611	0.96
9	26	0.029	2.2	9.1	0.1	1	22	620	641	620	641	0.95
10	26	1.3	97	3.9	7.5	1	23	650	672	650	673	0.93
11	26	0.0002	0.015	15.9	0.3	2	23	704	725	703	725	0.97
12	26	5.9e-06	0.00044	20.7	3.5	1	23	733	755	733	755	0.99
13	26	0.061	4.5	8.1	1.5	1	23	905	928	905	928	0.95
14	26	0.015	1.1	10.0	2.2	1	22	935	956	935	956	0.94
15	26	0.091	6.7	7.5	0.5	1	23	965	988	965	988	0.91
16	26	1.2e-05	0.00089	19.7	1.8	1	23	1013	1035	1013	1035	0.97
17	26	0.00014	0.011	16.4	0.9	1	23	1042	1064	1042	1064	0.98
18	26	0.0085	0.63	10.8	0.0	2	20	1091	1109	1090	1111	0.93
19	26	0.011	0.84	10.4	4.7	1	23	1156	1179	1156	1179	0.96
20	26	0.02	1.5	9.6	0.4	1	23	1216	1239	1216	1239	0.96
21	26	0.00099	0.073	13.7	3.5	1	23	1261	1284	1261	1284	0.97
22	26	1.4e-05	0.001	19.5	0.1	2	23	1312	1333	1311	1333	0.95
23	26	4.7e-05	0.0035	17.9	2.9	1	23	1339	1361	1339	1361	0.99
24	26	2.3e-06	0.00017	22.0	2.0	1	23	1367	1389	1367	1389	0.97
25	26	5.9e-08	4.4e-06	27.0	2.4	1	23	1395	1417	1395	1417	0.99
26	26	0.00073	0.054	14.1	0.3	1	22	1423	1444	1423	1447	0.91

Sequence Information

Coding Sequence: ATGTTACCGACCGATATATGCCGCACCTGTGCGCAGCATGATGTAAATTTGTTTCCGCTCTCTACGTGCACCGAGAAATATgcaaacaaaagtttctatGACATGTTGCATGATTTAACACAAAACGATcCCTTAATGGAACACTCAGATGATAATCTGCCCCAGTATTTGTGTGGCGACTGCTTGCATAAACTGGAAGAGGCATATGCATTTGTGTTGCAAGCTCGTCAGGTGCAGGAGCAACTGTTGCTCAAAATAAGCAAAGGCTTGCAGTGTCTGGATGAGACACCCATAGACATAGCATCGCAGCACATAAAGACAGAAGCCGACATGGCCTTGGAGCAAACCAATTATGGCGCCGATGATAAAGTTGCAACTGTGTCTCGGGCTGCTCTAAAGATGCAGCCGGAGAGTGAGAGCGACAGTAGCCAGGCAGACGTGGCTGATGATGATGTGCTGGATTTTAAGCCCACACAGCTGAGACGCAGCACTCGGAAGACAACACTTTGCGCAGACAGCGAAAATGAAGCAAAttgTGAAAATTTAACTGTAGTGCCGGTCAAGCGTCGTCGCGGTCGCCCTGCGCGTATTCCCAAAAAAGAAACCATCAACAAGGACGGACGACATGCGTGCGAGGTGTGTGGCAAGACTTTTTCTTGGCATCGCGACATGCAACGCCACGCTCGCATCCACTTTGAGCAGGCTGGCTACGTGTGTGACAGCTGTGGCAAGGGATTCCTCCGCAAGGACAAGTACACGTTCCATTTACGTTCGCACGAGAAGCGCCAAGCCAAGCGGCAGGCTTTGCAGCTGGGCAACGAATGGCGATTTGCGGAACGCCTGTACAGTTCAGGACGCCTCAAGCGTGTGGAGTGTAAGCTGTGCGAATTGAAGTGTCAGCGGATTCAGGAACTTCGTGAGCATCTGGCCAGCCATGTCAACATTGAAACATTGTCGAGTCTCAGCGTTAATAGCGATGTTATCCTGGAACAGTTTACCAGCCAGCAGCTGGACTTGATGCAGATTAAGCAACAGGTGTGTGCGGACATAGCCAAGGGAAGTGAACATCTGGATAAATACAGTGTGGTGGTCAATGCATATGGCTATGAACTCTGTCTGAGCGACTCTGACGAGGAGTTGGCAGGACTACCGCCTCCTTATCAATGCCTGGTTTGTAAAACTCACTTCTCACGCAAATATCGCCTGATGCGGCACACGCTGGAGGAGCACACTCAACCGACAGCTGTGACATCTCCTTGGCAACGTTGCAACTATTGTCAAATTGGCTTTGTGTGTGTCAAGCTTCTGGAACAGCATCAGCGCACACAGTGCCATAATCAGTTGAAACGTTATAGTTGTCCCAATTGTCCAGGCAAATTTATTTGGCGACAGAATCTGAAACATCATGCGTGCTCCCATCGCACGAGATCTTCAGAGGCACAGGATCAGGAGAGAAGTCTGGGCCGACAGATTCAGTGCTGCCTTTGCGATGAGCAACTAGAGAGTATGTCAGCACTACGTGCTCATCTAGTCACACACTGCGATGGACAAAGCGGCATTGATCCAGATCGAGGATCCACCTTCTTTCGTTGTAATCCAGATGGTTCCACCTGCAACCAGACGGAGCTCAGTATACGAATTGCGAGTGATTTTGGAGCAGAGGATTATGGTCGCTACTTCAATGCCTCCACAAGCAGCGGCCAGGAACTGGATTTCTTTGACTCTGATACGGATTTAAGCGATCaatcagctgctgctgtgcatTCGTGCACTTTGTGTGGCCAGAGCACACAACGCCTTGCCCTGCTGCTGAAGCATCAACAGAAAGATCACAGTGAGGTGATGGACACATTGCCTCATGTGTGTGACAAGTGTGGATTGGGATTTGTGGCTGAACCGCTGCTTCAGCAGCATCGTCGACGCATCTGTGCGAAGCGGCATGCAAAGTACCTTTGTCAACATTGCAATCTCCACTTTATCTGGCACTCGAACTACGAGCGACACATGGATCTACATCACGAAGCGGAGGCGGAAGCAGGGACAGATGATGTTCCTGATCGTGTGCCCAATACCAGACTAAGAAGCAAACGCCAACAAGCTGCCAAATTACAGTGCAATGAATGTGAAAAGGTCTTCATCTGGCCAAAGGATCTGACGCGTCATAAGCGCATTCATCAGCCGCAGGCATCGGCACAGTACGAATGCAGCTACTGTGAGCGCAAGTTTCATCGCAAGGATGGCCTTAAGTCCCATATGCGTGTTCATGGCGAGCAGCATTCAGATGCGACGGTTATGTCCAACAGCGATCCTGATCCGTCGATGTTGCAGCGGATGCCAATGGTGTTGACGCAATTGTGCCAACCAAATGGATGCAAGCTGATTCAATGCATGATCTGTCTCTCTCAGCACACGAAGATATCTGATCTGCGCACGCATTTGGTGAAGCATCAGTTTGTTGTGGAGTTTGCGGAGGATCGTGCCAGGCCGGAGAACATTGCTAGTATTTGCCGGTCCCTATATCCGGAGCTGGTTACTCCGTTGGATAAGCAACAATTGATTGATCGCATTCAGATTGATGTGGGCCTGGGCACTGAGTTGGAAAGATTCATTTCGATAACCAACGAGGCAGGCATTGAGCTTAGCTTAGATAGCAGCGAAACTGACTCAGATTCGGACTCGGCCGAAGTGGAAAGGATCAGCAGTGGACGACAATACAATTGTGATCTTTGCCGGTTGAAGTTGCCTCGTAAACATCAACTCTATGCCCATCAGCTGGAGCAACACACATGGCAACAGGCCACCCACATTTGTACCCACTGTCAGGCCAGATTCATCACTGAGCAGTTGCTGGAGCACCACTATCGTAGTCTCTGTCGCAATGTCCACAAGCGTTTCCTTTGTCGGAAGTGTCCATTACGGTTTCGTTGGCGTGACAACCTCAAGCTGCACACGGACGTGGCACATCAGGAAGCAACTGGAGAACAGACGAACTTGGGCATCCAATTAAATGGGGCAAGTCTACTCCCTGTTGTCAGCTACGATTGCAGCGAGTGTAATCGCAGCTTTAAAATGCAGAAGGATCTCACACGGCACACACTGATGCATGCCCAGGAGTCGAGCATTTATCGATGTCGTTGGTGTGCCCGTCGATTCTATCGCCAGGCGAATCTCCTGCAGCACATTGAGCGTCATGGCATCAATGCCACACAGCTGCCCTATGCCGAGTCCCTACTCAATGCCAGCCGTCATCCCCATGGTCAGAAATGCATTCAATGCAAGGTGTGTGATATACGTTTTCCCACAATTGCCGCACTGCGTTCCCATTTGGCGTCCACACCGAACGGGACTCATCATGAGATGGGATCGATGCTCAACTACTCGATTACTAACCAGCTGGGCTATGAGCTGCACTTGGAAGACTCGGAGACGGATGAGGAGGCCAAGCCGCCTGGAATACCCACACACTACACCTGCAGCATGTGTCAGCTGCGTTGTGTGCGGAAATATGAGctgcatcagcatcagcaggcCATGCATCGATTGGAACGGATTACCGAGGGCTGTGATCAGTGCATCTATAAGAGCGTTTCCCCGGATCTTATCGCCTATCATCGGCGTGTACAATGTTGCAACACGGAGAAGCAATTCAAATGCGTTAACTGTGGTTACAAGTTCATGTGGGAGTCGAACCTGCTGCTGCACATTCAATTGCAGCATCCTAGCAATAAACATCATGAGGAGGTGCCTGCTCCTGAGACACCCACTGTCGAGTGTCAGATCTTTCAGTGCGGTCAGTGCCCGCGTAAATACAATCGCAAGGATCGACTGACAGCCCATGTAAAGAAGTGTCATGCACCAGGTGCAGTTGATCCAACTGAGTGTCCAACAAAAACATCGACGTCTTCAAGTGTCTCCAAGCAACAGAAAAGTTTCCTTTGCGCCTTCTGCGGCAAGGCGGTGAGTTCCTCCTCTAATCTCATTATACACATACGTCGTCATACTGGCGAGAAGCCCTTCAAGTGCGACTATTGCGACATGGCTTTTCCCCGCTCGTCCGATCTGCAATGCCATCGACGCACCCACACTGGCGAACGGCCACATGTCTGCACCGTGTGCCAAAAGGGATTCGCCCGCTCCTACAAGCTCCAACAGCATATGCGCATCCATAACGGCGAACGTCCCTACAAGTGTACCTACTGCGACAAAAGCTTCACCCAGTCCAATGATCTGACACTCCACATACGACGACACACCGGCGAGCGACCCTATCAATGTGACACCTGCGGGGAACGCTTCATTCAAGGGACGGCCCTCAAGAATCATCGAATGCAGAATGGCCATTACGAGGCAGGGGATGGCCTAGCTAAAGTTAATTAA
Protein Sequence: MLPTDICRTCAQHDVNLFPLSTCTEKYANKSFYDMLHDLTQNDPLMEHSDDNLPQYLCGDCLHKLEEAYAFVLQARQVQEQLLLKISKGLQCLDETPIDIASQHIKTEADMALEQTNYGADDKVATVSRAALKMQPESESDSSQADVADDDVLDFKPTQLRRSTRKTTLCADSENEANCENLTVVPVKRRRGRPARIPKKETINKDGRHACEVCGKTFSWHRDMQRHARIHFEQAGYVCDSCGKGFLRKDKYTFHLRSHEKRQAKRQALQLGNEWRFAERLYSSGRLKRVECKLCELKCQRIQELREHLASHVNIETLSSLSVNSDVILEQFTSQQLDLMQIKQQVCADIAKGSEHLDKYSVVVNAYGYELCLSDSDEELAGLPPPYQCLVCKTHFSRKYRLMRHTLEEHTQPTAVTSPWQRCNYCQIGFVCVKLLEQHQRTQCHNQLKRYSCPNCPGKFIWRQNLKHHACSHRTRSSEAQDQERSLGRQIQCCLCDEQLESMSALRAHLVTHCDGQSGIDPDRGSTFFRCNPDGSTCNQTELSIRIASDFGAEDYGRYFNASTSSGQELDFFDSDTDLSDQSAAAVHSCTLCGQSTQRLALLLKHQQKDHSEVMDTLPHVCDKCGLGFVAEPLLQQHRRRICAKRHAKYLCQHCNLHFIWHSNYERHMDLHHEAEAEAGTDDVPDRVPNTRLRSKRQQAAKLQCNECEKVFIWPKDLTRHKRIHQPQASAQYECSYCERKFHRKDGLKSHMRVHGEQHSDATVMSNSDPDPSMLQRMPMVLTQLCQPNGCKLIQCMICLSQHTKISDLRTHLVKHQFVVEFAEDRARPENIASICRSLYPELVTPLDKQQLIDRIQIDVGLGTELERFISITNEAGIELSLDSSETDSDSDSAEVERISSGRQYNCDLCRLKLPRKHQLYAHQLEQHTWQQATHICTHCQARFITEQLLEHHYRSLCRNVHKRFLCRKCPLRFRWRDNLKLHTDVAHQEATGEQTNLGIQLNGASLLPVVSYDCSECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGINATQLPYAESLLNASRHPHGQKCIQCKVCDIRFPTIAALRSHLASTPNGTHHEMGSMLNYSITNQLGYELHLEDSETDEEAKPPGIPTHYTCSMCQLRCVRKYELHQHQQAMHRLERITEGCDQCIYKSVSPDLIAYHRRVQCCNTEKQFKCVNCGYKFMWESNLLLHIQLQHPSNKHHEEVPAPETPTVECQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVDPTECPTKTSTSSSVSKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRMQNGHYEAGDGLAKVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558059;
90% Identity: -
80% Identity: -