Dkok010426.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
znf711
Assembly
GCA_035042145.1
Location
JAWNLT010000346.1:9531751-9533055[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 7.4e-06 0.00047 20.4 0.1 1 23 168 191 168 191 0.97
2 8 1.1 71 4.1 10.7 1 21 197 217 197 218 0.93
3 8 0.00099 0.063 13.7 1.8 1 23 235 257 235 257 0.97
4 8 1.2e-06 7.4e-05 22.9 0.2 1 23 263 285 263 285 0.97
5 8 7.6e-08 4.9e-06 26.7 0.2 1 23 291 314 291 314 0.96
6 8 2.4e-05 0.0015 18.8 2.3 1 23 320 342 320 342 0.98
7 8 0.00035 0.022 15.1 0.1 1 23 348 370 348 370 0.98
8 8 5.1e-06 0.00033 20.9 2.7 1 21 376 396 376 397 0.93

Sequence Information

Coding Sequence
atgactGCAGAATTGAGTGAACTACTTTGCCGCGTCTGCCTGAAGCAGGACGAGCTCCTGGTGGACATCTACGAGCATGTGGAAGAGCAGCAAACGGATCTATGTACCCTACTCGAACGCTGTGGCGATATCAAAgtCGAAAAGTCTGATAATTATCCAAAGTACTTATGCCAAGAGTGCACCAAGGAGCTTCTAATTGCGGCCAAGTTTCGCGACAAATGTGCGGCAACGGAACAAGCTCTAAGGCAGGGAAAACGGCAGCGTTCAGAGGACGAAGCAGCACACTTGGCAATAAGCGAATTGGCCAAAGAGGAGTTGGTGGAGGATGATGAGAACACAATAGATGCAAATGATATTATAGTGTTCGATCCGAGCGAGCATGTTGAGCTATACGAGGAATGCGAAACGGAAGAGCTGGCcgtaaaagagagagaagcacCAGAGTCAGCTGTGAGAGAAGAGTCGATAGAAGAACTTAATCCCATACAGTTAAATGCCAACTACACCTGTGATGATTGCGGTGCCGTCTTTCAGCAGACGGCGACGTTGCAGCGGCACATAGCTAAAGTACATCCTACTGCAGATATCTACAATTGCATGCACTGTGCTCATTGCTTTACCCATCACATAAATCTGCAGAAGCACAGCTGCACAACTGGCTGCAGTGCGCCGCCGGGGAATGAAGGGGTGGCACGTACACGTCATCGCTGCGTCTACTGCGGCAAGTGTCTGCAGTCGGCTCCCAGTCTGGTGATGCATCTGCGTCTGCACAACGGCGAGCGGCCCTTTGCCTGCGATGTTTGCCCCAAGACATTCAGAACCAATGGCGGACTTGTCGTCCATCAGAAGCGACATCTCAAACTGATTGAGTTTGAATGCGAGTATTGTGGCAAAGGTTTCGTAGAGTCCAGCAATCTAAAGCGACACATTGCCTCGCTGCACACATCGGAGCGTCCGCACAGTTGCACCATCTGTCAGCGCTCCTTCGCGCGCGTCTATTTACTTGAGCTGCACAAGCGCACCCACACGGGCGAGCGTCCGTATGCCTGCTCCTTGTGCGGCAGCAGATTTGCCCAGCTGAGCGTTCTACGCTCACACGAGAGAATCCATTCGGGCGAGCGGCGACATCGCTGCGATGTTTGCCAGAAGACCTTTAGTCGCTTGAGCCAGCTGAAAAAGCATAAGCTCAAATCCTGCCTGCCTGCGGACACACAAACCGTAAATGAAGTTGTTGTCATGGCTTGA
Protein Sequence
MTAELSELLCRVCLKQDELLVDIYEHVEEQQTDLCTLLERCGDIKVEKSDNYPKYLCQECTKELLIAAKFRDKCAATEQALRQGKRQRSEDEAAHLAISELAKEELVEDDENTIDANDIIVFDPSEHVELYEECETEELAVKEREAPESAVREESIEELNPIQLNANYTCDDCGAVFQQTATLQRHIAKVHPTADIYNCMHCAHCFTHHINLQKHSCTTGCSAPPGNEGVARTRHRCVYCGKCLQSAPSLVMHLRLHNGERPFACDVCPKTFRTNGGLVVHQKRHLKLIEFECEYCGKGFVESSNLKRHIASLHTSERPHSCTICQRSFARVYLLELHKRTHTGERPYACSLCGSRFAQLSVLRSHERIHSGERRHRCDVCQKTFSRLSQLKKHKLKSCLPADTQTVNEVVVMA