Basic Information

Insect: Drosophila kokeensis
Gene Symbol: -
Assembly: GCA_035042145.1
Location: JAWNLT010000263.1:4688336-4690043[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00012 0.0075 16.6 3.1 1 23 96 118 96 118 0.97

2 11 7.1e-07 4.5e-05 23.6 3.4 1 23 124 147 124 147 0.97

3 11 1e-05 0.00067 19.9 0.5 1 23 153 175 153 175 0.97

4 11 4.5e-05 0.0029 17.9 0.6 1 23 181 203 181 204 0.95

5 11 2.3e-06 0.00015 22.0 0.7 1 23 211 233 211 233 0.97

6 11 0.0036 0.23 11.9 1.3 1 23 239 262 239 263 0.97

7 11 0.0011 0.072 13.5 0.4 1 23 268 290 268 290 0.98

8 11 2.2e-05 0.0014 18.9 2.7 1 23 296 318 296 318 0.98

9 11 1.3e-05 0.00083 19.7 2.5 1 23 324 346 324 346 0.99

10 11 0.0025 0.16 12.5 1.3 1 23 352 377 352 377 0.95

11 11 0.0027 0.18 12.3 0.2 1 19 383 401 383 403 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00012	0.0075	16.6	3.1	1	23	96	118	96	118	0.97
2	11	7.1e-07	4.5e-05	23.6	3.4	1	23	124	147	124	147	0.97
3	11	1e-05	0.00067	19.9	0.5	1	23	153	175	153	175	0.97
4	11	4.5e-05	0.0029	17.9	0.6	1	23	181	203	181	204	0.95
5	11	2.3e-06	0.00015	22.0	0.7	1	23	211	233	211	233	0.97
6	11	0.0036	0.23	11.9	1.3	1	23	239	262	239	263	0.97
7	11	0.0011	0.072	13.5	0.4	1	23	268	290	268	290	0.98
8	11	2.2e-05	0.0014	18.9	2.7	1	23	296	318	296	318	0.98
9	11	1.3e-05	0.00083	19.7	2.5	1	23	324	346	324	346	0.99
10	11	0.0025	0.16	12.5	1.3	1	23	352	377	352	377	0.95
11	11	0.0027	0.18	12.3	0.2	1	19	383	401	383	403	0.97

Sequence Information

Coding Sequence: ATGGTACGCAGTCGTCGCAGCCTCTCCAAAGAGGATGCCGCCTCGGTGCTCACCGACAGTGGCATTTCGCTCTCATCGCCGCCGGCGGCACGCGAATCCTCGCCACAAGCAACAGGTGGCGTCAAGCGACGCAAGCGAAGTGTCAACAGTGTACAAGATGTGTATGCGGCTGATGGGGAGTCAGAAACTCAACCGGATTTCTCCGATGACGACACGGATGCCGATGCGGATTACGTTCAGCCGGTGGCAAAGAGATCGCGCAAAGCGGACACAGGCAAACGCAAGCACGTGTGCAGTCATTGCTCGAAGAAATTCGGTGGCAGGACAGATCTGCTGCGTCACATGCTCATCCACTCGGATCAGCGGCCGCACAAGTGCAGCGAGTGCGGCAAATGCTATCGGCAGGCCGTCAATCTGAAAAATCACATCACCACCGCCCACGAGCGCAAGAAACAGTTCGCCTGCACCGAATGCCCCAAATCGTTTGCTCTAAAGGAACGCCTAAAATTGCACATGCGTCTGCATTCGGGCGAGAAACCATATCCATGCTCACTCTGCGATAAACGTTTCGCCCGCGGTGGCCAGttgcaacagcatgTGGTATCGCATCACAAGATGAGCATACAGCAATTCAATTGCACCAACTGCTCAGCAAGCTTCTCGACGAATGCCAATTTGCGCGTGCACATGGAACGACACGAGCAGGGCATGGAATACAGATGCTTCATATGCAAGAGTGAGTTTCCAACCGAATTGGCGCTGCGTACGCACATCAATAAGGAGCACCACAAACTGCGGCAATTCTATTGTCAAATATGCCAGAAGACCATCGAAACGGATGAGGACCTGGCCAGCCACCTGAAGAAGCATTCATCGGTTAAGGCGCACGTTTGCGAGGTGTGCAATTCGTATTTCACCCAAAAGTCCCAATACAATGTCCATATGCGAATGCACACGGGAGAGCGGCCATATCAGTGTCGGATCTGTTCGCAGACATTTGCTCATTCCAGCGTGCTGAAGCTGCATATACGTAAACATACCGGTGAGAAGCCGTTTCGTTGCCAGCTGTGCACGGATGAGGTGGCCTTCTCGCAGTTGGCGCATCTCAAGAATCACATGAAGAAGATACACAAACAGCAGAAGCCCTACATGTGTCCAACCTGCCATGAGTTCTTCAAGATCAAAGTGGAGCTGCAGGCGCATTCTGTACGGAGCACCAAATGCCAGTCAACGGAGGATCTCAACGGTGGAGATCAGACGGCAGATATGCAGAAGCTATCCAGTATACGCTTTAATATGGCCGTGGTGCTAAAGAAGATTAGCACGGCACAGAAACTGCGTCAGCTGGGCTATGAGAAGCGTTTAATTGATAATGTTATCATTGCCTCACTGAAACTCGCACAGCGTCCGTGCCATGACGATGCGACACTGACGCCCTTGGCCAGGCTCCGTCTGAATGTGGAGGAGTTTCTTAAGTGGATTGTGCCGGCGCAAACCATGCAAAAGTTTCAAGAGGAGGAACTGCTCTCGGTCGATACGATACTCGACAGGATTGCGTCCAACTACATGAAACAAAAATAG
Protein Sequence: MVRSRRSLSKEDAASVLTDSGISLSSPPAARESSPQATGGVKRRKRSVNSVQDVYAADGESETQPDFSDDDTDADADYVQPVAKRSRKADTGKRKHVCSHCSKKFGGRTDLLRHMLIHSDQRPHKCSECGKCYRQAVNLKNHITTAHERKKQFACTECPKSFALKERLKLHMRLHSGEKPYPCSLCDKRFARGGQLQQHVVSHHKMSIQQFNCTNCSASFSTNANLRVHMERHEQGMEYRCFICKSEFPTELALRTHINKEHHKLRQFYCQICQKTIETDEDLASHLKKHSSVKAHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICSQTFAHSSVLKLHIRKHTGEKPFRCQLCTDEVAFSQLAHLKNHMKKIHKQQKPYMCPTCHEFFKIKVELQAHSVRSTKCQSTEDLNGGDQTADMQKLSSIRFNMAVVLKKISTAQKLRQLGYEKRLIDNVIIASLKLAQRPCHDDATLTPLARLRLNVEEFLKWIVPAQTMQKFQEEELLSVDTILDRIASNYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324297;
90% Identity: iTF_00574209;
80% Identity: -