Basic Information

Insect: Drosophila kokeensis
Gene Symbol: Znf296
Assembly: GCA_035042145.1
Location: JAWNLT010000262.1:233762-235348[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2e-05 0.0013 19.1 4.3 1 23 218 240 218 240 0.96

2 11 0.00028 0.018 15.4 2.7 1 23 246 268 246 268 0.99

3 11 7.9e-06 0.00051 20.3 1.6 1 23 274 296 274 296 0.98

4 11 5.9e-06 0.00038 20.7 2.6 1 23 302 324 302 324 0.98

5 11 2.9e-07 1.8e-05 24.9 0.8 1 23 330 352 330 352 0.99

6 11 2.2e-06 0.00014 22.0 4.7 1 23 358 380 358 380 0.98

7 11 2.5e-06 0.00016 21.9 1.0 1 23 386 408 386 408 0.99

8 11 1.8e-05 0.0012 19.2 5.1 1 23 414 436 414 436 0.98

9 11 2.6e-05 0.0017 18.7 0.1 1 23 442 464 442 464 0.98

10 11 1.7e-07 1.1e-05 25.6 0.4 1 23 470 492 470 492 0.96

11 11 8.4e-06 0.00054 20.2 2.1 1 23 498 520 498 520 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2e-05	0.0013	19.1	4.3	1	23	218	240	218	240	0.96
2	11	0.00028	0.018	15.4	2.7	1	23	246	268	246	268	0.99
3	11	7.9e-06	0.00051	20.3	1.6	1	23	274	296	274	296	0.98
4	11	5.9e-06	0.00038	20.7	2.6	1	23	302	324	302	324	0.98
5	11	2.9e-07	1.8e-05	24.9	0.8	1	23	330	352	330	352	0.99
6	11	2.2e-06	0.00014	22.0	4.7	1	23	358	380	358	380	0.98
7	11	2.5e-06	0.00016	21.9	1.0	1	23	386	408	386	408	0.99
8	11	1.8e-05	0.0012	19.2	5.1	1	23	414	436	414	436	0.98
9	11	2.6e-05	0.0017	18.7	0.1	1	23	442	464	442	464	0.98
10	11	1.7e-07	1.1e-05	25.6	0.4	1	23	470	492	470	492	0.96
11	11	8.4e-06	0.00054	20.2	2.1	1	23	498	520	498	520	0.98

Sequence Information

Coding Sequence: ATGGAGCAGATTTGCCGTGCATGCAAAATCAGCTCCAGCAGCCTGGTGAATATATTCACAGAGGGGCAGCCCAGTCTGGCGGAGATGTTGAGCGAGTGTGCTGCCTGTGAAATCAATCGAAATGATGCACTTCCTCAGCAGCTGTGCCACTCCTGCGTCATCGCTGCACAAAATGCGTTTCGCTTgaagtgcaactgcaaacaaaaagaaccAAAAACAGATGTTTGccgcatttgcagcagcaactcaactacgctaattaaaatcaatgccaagcggcagcagccacGGGACGAACCCAGTCTAGCGGAAATGATAAAAGAGTGCATTAACTGTCAGACAAATCCCAGGGATCAGATATGCCTGACCTGCATTCTGAGCGTTATAAACGTTTTTCAATTCAAGCGCAGATGTGAGCAGAGCCAGCAGCAGattaaaactgaaattcaaGAAACTGATTCTGTTGAACATGTGCTGTCCGAGAACAGCTTAAAAATTGAGCAACAAGAATACAGCATTAAAATCGAAGTCACCGAAAATGAAGAAGACTTTGAATGCGAGGAGACTCACATTATGTTGGAGGAGTCAAAGTGTCCACCGACTGTAAATAATCATATCCTAGCAGAGATTGAAGTGGATGCAAAGAAGAAACACGCGTGTGAGAAGTGTGGCAAAAGGTTTTCGAACACTTGTAACCTTCTCGTGCACAGACGCATCCATTCCGGGGAACGTCCATTCAAGTGTTGCGAGTGTCCAAACGATTTCACAAGCCGCAAAGTTCTCAAGGATCACATGCGCATCCACACCGGCGAACGGCCATTTCAGTGTGACCAGTGCCCAAAGGCCTTTGGCCGCAATTGTGCTCTGGTTAAGCACATGTTCACGCATACGGGCGAACGGCCCTTCAAGTGCAGCCAATGCCCTAAAGCCTTCTATCAGAGAGGGCATTTAAAGATCCATAATCGCATTCATACTGGGGAGCAACCATACCAGTGTCCCCATTGCCCCCGGGCCTTTCCACGCAAGGAGTATCTAGTGACGCACCTGCGACTGCATACGGGCGAGCACCCACACCAGTGTCCCCACTGTCCCAAGTACTTTTCCCGTAGCAAAAACTTGGAGATGCACTTGACCACGCATTCGGGTCAGCAGCCCTATCGGTGTCCTCATTGCATCAAGGCGTTCACCGCCAATTCCAATCTACAAATACATATCCGGAGTCATACGGGCGAACGTCCGCACAAGTGTCCCCACTGTGCGAAGGCATTCAGCCAGAACGTCTGCCTCCAGAATCACATACGCCTCCACACCGGCGAACGGCCGTTCCAATGTGCCCAATGCCCCAAGGCTTTCGCCAGCAAAGGGGGATTGTACAATCACAGTCGTGTCCACTCCGGCGAACGTCCCTTCCAGTGTCCCAAGTGCCCGAAACGATTTCCGCGCAACGAGAACCTGCGCAATCACATTGGCCTCCATTCCGCGGATCGACCGTACAAGTGCACCCTGTGTCCCAAGGACTTTACCCGCCACGAGAGTCTGGCCCGGCACAAGCTGATTCATGCCAAAAATGAAAGATCAAAAGATTAG
Protein Sequence: MEQICRACKISSSSLVNIFTEGQPSLAEMLSECAACEINRNDALPQQLCHSCVIAAQNAFRLKCNCKQKEPKTDVCRICSSNSTTLIKINAKRQQPRDEPSLAEMIKECINCQTNPRDQICLTCILSVINVFQFKRRCEQSQQQIKTEIQETDSVEHVLSENSLKIEQQEYSIKIEVTENEEDFECEETHIMLEESKCPPTVNNHILAEIEVDAKKKHACEKCGKRFSNTCNLLVHRRIHSGERPFKCCECPNDFTSRKVLKDHMRIHTGERPFQCDQCPKAFGRNCALVKHMFTHTGERPFKCSQCPKAFYQRGHLKIHNRIHTGEQPYQCPHCPRAFPRKEYLVTHLRLHTGEHPHQCPHCPKYFSRSKNLEMHLTTHSGQQPYRCPHCIKAFTANSNLQIHIRSHTGERPHKCPHCAKAFSQNVCLQNHIRLHTGERPFQCAQCPKAFASKGGLYNHSRVHSGERPFQCPKCPKRFPRNENLRNHIGLHSADRPYKCTLCPKDFTRHESLARHKLIHAKNERSKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558881;
90% Identity: iTF_00610044;
80% Identity: -