Basic Information

Insect: Drosophila kikkawai
Gene Symbol: GFI1
Assembly: GCA_018152535.1
Location: NW:23568270-23586975[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00018 0.011 15.9 3.6 1 23 506 529 506 530 0.96

2 6 0.00028 0.017 15.3 0.5 1 23 535 557 535 557 0.97

3 6 3.2e-07 1.9e-05 24.6 1.9 1 23 563 585 563 585 0.98

4 6 1.1e-05 0.00065 19.7 4.2 1 23 591 613 591 613 0.97

5 6 1.9e-07 1.2e-05 25.2 2.5 1 23 619 641 619 641 0.98

6 6 3.9e-05 0.0023 18.0 5.0 1 23 647 670 647 670 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00018	0.011	15.9	3.6	1	23	506	529	506	530	0.96
2	6	0.00028	0.017	15.3	0.5	1	23	535	557	535	557	0.97
3	6	3.2e-07	1.9e-05	24.6	1.9	1	23	563	585	563	585	0.98
4	6	1.1e-05	0.00065	19.7	4.2	1	23	591	613	591	613	0.97
5	6	1.9e-07	1.2e-05	25.2	2.5	1	23	619	641	619	641	0.98
6	6	3.9e-05	0.0023	18.0	5.0	1	23	647	670	647	670	0.97

Sequence Information

Coding Sequence: ATGGACGTAGCCAAAATGCAAGCCGCTTCCGGCCAGCATCTGCTGCATCCCGCTGCGCCGCCCGCCCACCAACACCACCTGCCGCTCGACTACAGCTTGGGCAACTTCAAGCCGGCCATAGCGGCCGACTTTCCCGGACCCTTCCTcgccagccagcagcaacagtccTCCACGGCCTCCAATTCCGCCTCGTCTGGTTCCGGTACCGGTGCCGCTTCCGCGTCTACTTCCGCCTCGCTGCAGGTGCGCGATCTCAGCGCCCTGACGGCCATGGCCACGATACCCTCGCCCACGCAACTCCTCCAGCAGCGCATCCAAATCTCTGCGGACGCGGCCCTGGGTCACCaccagcaacatcagcagcaccaGGCGGCCCAGAATCCGCCGCAGCCACCGATGCCGACGGCCTCCACATCGCCGCACGAATACGCGCCCATCTCCGCATTCAAAGCGGTAACGCCCAAGAAGCGCAACTCCGACGATGCCGCCCTGGCATTTAGCATTAGCAGACTGGTCAAGACTGAACTCCTTACAGCGGCTGTTGGCCTAAAGCCGCTGACTTCGCTGGAGGACAACAACAACTCCATCTCTATGTTGAGCAAAAACCAGatgcagcagcaccaacagcaccAGCAACTCCAGCAGCCACGATCCAAACCGGCCTTCATCAGTGCCAGCGAAAAGTTGAGGCGACAGTCGCGATCCCGCTCCCGTTCGCGGTCCCGGAGTCGCTGCTCCTCGCAGATTGACATGGAGGACGCGGAGTCCCACCATTCGCATCGTTCGCTTCACTCTCGGTCGCGATCACGCTCCCGCTCCCACTCGCGCTCCCGCTCGCATTCCAGTAGCTCGTCGGTGGAGCTGGAGGTGGACTCGCCACCGGGCAGTCCGCGGATCAGTTCACCCAGCACCGCTTCCGCCTCGGAGCTGCTTATAACAGCCAATGGAGGCGCCAGGAGTATCGGGTCCAAGAAGTCCGATCTCTTTTCCGTTTCTGCGTTGCTGCGAAGGGATGAGCCACCTCAAAGACGCACCCCACGCAGCCCGCCGCTGGGTCACATGGCCGCCGGTGGCCTGCCCATGCCCTTTAATCCGCTGGAGGCTATGCGCCAGGGCTATCCGCCCAACTACGACGCGGCCATGTTCCAGCGTCCTCTCTTCTCGCCTGCCCTGCCCTTCTTTGCCGCCGTTGCCTTCCACCAAggtcagcagcaacagcagcagcagcagcaacaacagcagcagcagtctgGCCTGGGAGCGGGCTATCATCCGGACTCGCAGGAAAATCTCTTCCGTCTGCGGAGTCTAATGGTGCCGCTGCAATCCGCCGGACAGAACAACTccacagcggcagcggcggcggcggcagcagctgcgGCGGCCGTCGGCGTGGGTGTCGGAGTGGGTGTGCCACCCAATGGTGGGCACCTGGGACTGCCGCACTCGCCGCACCTGCACCACTTCCACCACATGGCCGCCAAGTGGCCGGGCCTGCACCAATTCAGCGACCTGTACTCGTGCATGAAGTGCGAGAAGATGTTCTCCACGCCGCACGGCCTCGAGGTCCACTCCCGCCGGACGCACCACGGCAAGAAGCCCTATGCCTGCGAGCTCTGCAACAAGACCTTTGGGCACGAGGTCAGCCTCAGCCAACACAGGGCGGTGCACAACGTAGAGAAGGTGTTCGAGTGCAAGCAGTGCGGAAAGCGCTTCAAGCGCTCCAGCACGCTGTCGACGCACCTGCTCATTCACAGCGACACGCGGCCTTATCCCTGCAACTATTGCGGCAAGCGGTTCCACCAAAAGAGCGACATGAAGAAGCACACCTACATCCACACAGGTGAGAAACCGCACAAGTGCCAGGTGTGCGGCAAGGCCTTCAGCCAGAGCTCCAACCTGATAACGCACTCTCGCAAGCACACCGGCTACAAGCCCTTCTCCTGCAAGCTCTGCCACAAGTCCTTCCAGCGCAAGGTGGACCTGCGGCGCCACAAGGAGACCCAGCACACGGACCTGCGCGTTCACCTGGGCAAGGTGGACTTTAtgtcggcggcggcagcagcggcggcctCTGCCGAGCTGAgtgcagcagcggcggcagcaggcGGCGGTGGAGTGTCCCCAGCGAATCAGGGTGCACCGCCTCCGAACGGGGGACCCCCCCAGATGGGCGGCGGCCTCAACTGTCAGAAGGTGTCGCTGCTGGTATAA
Protein Sequence: MDVAKMQAASGQHLLHPAAPPAHQHHLPLDYSLGNFKPAIAADFPGPFLASQQQQSSTASNSASSGSGTGAASASTSASLQVRDLSALTAMATIPSPTQLLQQRIQISADAALGHHQQHQQHQAAQNPPQPPMPTASTSPHEYAPISAFKAVTPKKRNSDDAALAFSISRLVKTELLTAAVGLKPLTSLEDNNNSISMLSKNQMQQHQQHQQLQQPRSKPAFISASEKLRRQSRSRSRSRSRSRCSSQIDMEDAESHHSHRSLHSRSRSRSRSHSRSRSHSSSSSVELEVDSPPGSPRISSPSTASASELLITANGGARSIGSKKSDLFSVSALLRRDEPPQRRTPRSPPLGHMAAGGLPMPFNPLEAMRQGYPPNYDAAMFQRPLFSPALPFFAAVAFHQGQQQQQQQQQQQQQQSGLGAGYHPDSQENLFRLRSLMVPLQSAGQNNSTAAAAAAAAAAAAVGVGVGVGVPPNGGHLGLPHSPHLHHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKSFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAASAELSAAAAAAGGGGVSPANQGAPPPNGGPPQMGGGLNCQKVSLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00591916;
90% Identity: iTF_00606546;
80% Identity: -