Basic Information

Insect: Drosophila kikkawai
Gene Symbol: -
Assembly: GCA_018152535.1
Location: NW:13585481-13587192[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.6e-06 0.00039 20.4 0.3 1 23 211 234 211 234 0.90

2 8 4.7e-07 2.8e-05 24.0 2.5 2 23 256 278 255 278 0.94

3 8 4.7e-05 0.0028 17.7 0.3 3 23 304 323 303 323 0.98

4 8 1.6e-06 9.6e-05 22.3 1.0 1 23 329 351 329 351 0.99

5 8 2.1e-06 0.00012 22.0 1.8 2 23 358 379 357 379 0.97

6 8 1.1e-07 6.8e-06 26.0 0.8 1 23 385 407 385 407 0.99

7 8 2.2 1.3e+02 3.0 1.0 1 21 413 433 413 437 0.85

8 8 0.004 0.24 11.7 0.1 1 22 500 521 500 524 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.6e-06	0.00039	20.4	0.3	1	23	211	234	211	234	0.90
2	8	4.7e-07	2.8e-05	24.0	2.5	2	23	256	278	255	278	0.94
3	8	4.7e-05	0.0028	17.7	0.3	3	23	304	323	303	323	0.98
4	8	1.6e-06	9.6e-05	22.3	1.0	1	23	329	351	329	351	0.99
5	8	2.1e-06	0.00012	22.0	1.8	2	23	358	379	357	379	0.97
6	8	1.1e-07	6.8e-06	26.0	0.8	1	23	385	407	385	407	0.99
7	8	2.2	1.3e+02	3.0	1.0	1	21	413	433	413	437	0.85
8	8	0.004	0.24	11.7	0.1	1	22	500	521	500	524	0.91

Sequence Information

Coding Sequence: ATGGACTCCACCGACATAAACCTTAATATTAgtacctcctcctcctgtcgCGCCTGCCTGGGGGTGGACGAGGCCAACACAAGTCTTTGCCTGTACGACGAAATCGAGTACAACGGGATAAACATGGAGTTGTGGCAGCTTTTGCTGTTTGTCTCCAAAGTGAAGATGGCCGAGGATCCGAATCTTCCAGCCCAGATCTGTCAGACCTGCGCCCAGCGGCTAATCAGCGCCTACGAGTTTATCCTGGATGTGGAAAACTCAGAGAAGAAACTGCAGAGTCTGTCCCTGCCACAAGCTGAAGCGGCTGCGACCAAGCCGGACGAGGGGCATGTGGAGGTGGTGGAGCTGATTGACCAGGAGGAAGTAATTGATATGGAGGACTTCCTGCCTGCTGGTtacgaggagcagcaggcaaCCCTGGGGGAGTTGACCGAGGCTCCAAAATGTGATGTGGAGGATCAGCAGCTGTATGCCGTCGCTGATCCAGACTCTGAAACGGAAATTAAGGAGGACGAGGTTAACGCGGATGATGGTCAGCTTGGAGTGCCGCCAAATCAACATGAGATCACTCTCCCGCCAGCTGGATCTTCCAGGCTGGGCAGCCGTCTGACACATTCGAGTAACTTTATGTACAAGTGCGATATTTGTCCACGTGTCTTCGCCAAGAGCGAGTCCCTTCGACGACACTTTGACCTGGCTCACCGAAAGACGGCGGACATGGCTGCCCAGGAGTTGGCGGACGAGAGCAGCGGCACCGGCCTGCTCACCTGCGAGCATTGTCCGCGCACATTCAAGCGCCAGGACACGCTCCGGCGACACATGCTGGCATTCCACCCCGACGCACCGCTAGCTTCTGGGCCCGAGATGGAGGACACTTCGCCTCGCAAACGTGTTGCCAAGCGTCGAGATTGTCCCCATTGCGGCCTTAGCTTCCCTGCGTCCAGTCTCACCATTCACATCCGGCGGCACACCGGCGACAATCCGTACAAATGCACCCAGTGCGAAAAGGCCTATCCCCGCAGCCAGGATCTGACCCTGCACATGAGGCAGCACACGGGCGAGCGACCCAGCCAGTGTAAGATCTGCTCGAAGAAGTTCATTTCGCAAAACAAACTGGCGCGTCACATGCGTCTTCACACGGGCCAGCGGCCATATGTCTGCGACAAGTGCAATAAGGGCTTCGTGCAATCCAACGACCTCAAGATCCATATGCGACGCCACACGGGCGAGCGGCCGTACCACTGCGGCGTGTGCGGTGATAGCTTTGTGTGCGGCTCCCTGCTGACTATCCACCGCAACCAGATGGGCCATTACGAAGTCGGGCACAAAGAAACGGGCGCAGAAGGCTCCAACCTGAACGATCCGTATGTAAATGCCCGGGTGAGTAAGCGTCGGGCAGAGGACATTGAACGGATGCGCTTGCAGAGGGCTACCGAGGATCAAATTCAACAGCCAATGGAGGTTACTTATCAGCAGAAATCGCCACCTATTCTTTCCTACAAGTGCGGTGTCTGTGAGATGAATTTCAAGAGCGGTGCCCTGCTGACCATCCATCGCAATAACATGGCTCATTACGAGATCGGAAAGGTGGACTATGGCGACCCCTTTGGGGAGAAGCAGAAAAGGGTTAAATAA
Protein Sequence: MDSTDINLNISTSSSCRACLGVDEANTSLCLYDEIEYNGINMELWQLLLFVSKVKMAEDPNLPAQICQTCAQRLISAYEFILDVENSEKKLQSLSLPQAEAAATKPDEGHVEVVELIDQEEVIDMEDFLPAGYEEQQATLGELTEAPKCDVEDQQLYAVADPDSETEIKEDEVNADDGQLGVPPNQHEITLPPAGSSRLGSRLTHSSNFMYKCDICPRVFAKSESLRRHFDLAHRKTADMAAQELADESSGTGLLTCEHCPRTFKRQDTLRRHMLAFHPDAPLASGPEMEDTSPRKRVAKRRDCPHCGLSFPASSLTIHIRRHTGDNPYKCTQCEKAYPRSQDLTLHMRQHTGERPSQCKICSKKFISQNKLARHMRLHTGQRPYVCDKCNKGFVQSNDLKIHMRRHTGERPYHCGVCGDSFVCGSLLTIHRNQMGHYEVGHKETGAEGSNLNDPYVNARVSKRRAEDIERMRLQRATEDQIQQPMEVTYQQKSPPILSYKCGVCEMNFKSGALLTIHRNNMAHYEIGKVDYGDPFGEKQKRVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490224;
90% Identity: iTF_00533235;
80% Identity: -