Basic Information

Insect: Drosophila kikkawai
Gene Symbol: zfh1
Assembly: GCA_018152535.1
Location: NW:6586334-6592088[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.0016 18.5 1.0 1 23 153 175 153 175 0.97

2 15 0.00082 0.049 13.8 1.2 3 23 183 203 181 203 0.94

3 15 0.00027 0.016 15.3 0.2 1 23 370 392 370 392 0.98

4 15 0.00013 0.0079 16.3 0.8 1 23 398 420 398 420 0.98

5 15 1.4e-05 0.00084 19.4 2.3 1 23 452 474 452 474 0.97

6 15 0.0013 0.08 13.1 0.9 1 23 508 530 508 530 0.94

7 15 0.038 2.3 8.6 0.7 1 23 536 559 536 559 0.93

8 15 0.026 1.5 9.1 0.4 3 19 568 584 567 585 0.95

9 15 0.00015 0.0092 16.1 5.6 1 23 594 616 594 616 0.97

10 15 0.046 2.7 8.3 0.4 2 23 622 643 621 643 0.96

11 15 9e-06 0.00054 20.0 1.0 1 23 652 674 652 674 0.98

12 15 0.001 0.061 13.5 0.1 3 23 682 702 680 702 0.97

13 15 5.5e-05 0.0033 17.5 0.5 1 23 708 730 708 731 0.95

14 15 0.036 2.2 8.6 0.3 1 23 741 763 741 763 0.97

15 15 0.0056 0.33 11.2 0.2 1 23 1300 1322 1300 1322 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.0016	18.5	1.0	1	23	153	175	153	175	0.97
2	15	0.00082	0.049	13.8	1.2	3	23	183	203	181	203	0.94
3	15	0.00027	0.016	15.3	0.2	1	23	370	392	370	392	0.98
4	15	0.00013	0.0079	16.3	0.8	1	23	398	420	398	420	0.98
5	15	1.4e-05	0.00084	19.4	2.3	1	23	452	474	452	474	0.97
6	15	0.0013	0.08	13.1	0.9	1	23	508	530	508	530	0.94
7	15	0.038	2.3	8.6	0.7	1	23	536	559	536	559	0.93
8	15	0.026	1.5	9.1	0.4	3	19	568	584	567	585	0.95
9	15	0.00015	0.0092	16.1	5.6	1	23	594	616	594	616	0.97
10	15	0.046	2.7	8.3	0.4	2	23	622	643	621	643	0.96
11	15	9e-06	0.00054	20.0	1.0	1	23	652	674	652	674	0.98
12	15	0.001	0.061	13.5	0.1	3	23	682	702	680	702	0.97
13	15	5.5e-05	0.0033	17.5	0.5	1	23	708	730	708	731	0.95
14	15	0.036	2.2	8.6	0.3	1	23	741	763	741	763	0.97
15	15	0.0056	0.33	11.2	0.2	1	23	1300	1322	1300	1322	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGGACTATGGCGGCATCCAGTGGATACAGCACCATCCCGCTGCAGGCGACTCCTCCGAGACGGACATTATGGAGCACGAAGACGCCGACGGTGATGATATGGTGAGCGGAGCGGACGGCGACCCGGATGGGGACGGAGATGCCGACGTTGATCTGGACCATATGGCTGCCGAGAACCTGATCTTTATGGCGCGTGACGGCCAGCTGGGCGAGATTATCGCCGCCAACGAGGGAACCGTCCTGGTCACCGCCGATGGCACTACGGTAGCTTATGCGGAATCATTCGACGACGACGCCCAGGTGGTCACCGAGGAGGTCATCACGGATGACTGGGTGCAGCACCAGGGAGCCGAGCGCGTGGAAATCGCCGCCGAGCAGATAGCTGGCATCAGTAGCTCTCAGGAACTATTGGACATGGAGCAGGATGAGTATACGGCTCTGCGACCCTATCCCTGCGACTTTTGCAGCCGTCGCTTTCGGAAGAAGGCCAGCTTGAACAACCATATGCTGGCCCACCAAAACGACCGACCTCATCTCTGCAAGCTGTGCGGGGCACGCTTCTCACGCCGGGCGGAGCTCATTAGCCACTTTAAGGCCCACGCTGAAGCTCAAGATGCTGCAGATGCCgaggcagcagccgccgccgctgccgttTCGGGCTCTTCTTCCATAAAGTTCGAGAATCAAAGCCACAGGCAGACGGATGATCACTACTACGAACAGGAGTGGCCGCTGtatcagcagcaacatcagcagcaggagcaggaacagcaACAGGAACTAGGGCAGCATGAGCAGATGCTGCAACAGGAACAACAGCAACTTGTCTGCAACAGCGAGGTCCAGTTTGTGGCCAGCTACACAGCATCggtggctcctcctcctgctccgtCGCGTGGAAGAATAAGCAGGCTGAAGCCCAAGGAGGAGAGCAGCCAGTTCATCGTAATTACCGATAAGCCGGCACCCAGTGAGTTACGGGACTACATGGCCAGTGAGCCGGTGCCTCAGCCAGTGGTGCCCACATCTCAGCCCATGGCCATTGATGCGCCGCCTGCACCGCAGCCAAACTTCCCGGTGCTGGACGACAGCAAGCCCTTTGTGTGTCAACAGTGCGGATTGGCTTTTGCGCGGGAAAAGGCGCTGGTCTCTCACACAAAGAACCATCGCGTGGACTCGCCCTTCGAGTGTAACCAGTGTCAGGAGATGTTCTGGGACAACAGCAGCCTGCAGGACCACCAAAAGACGCATCAGTTTGAGGAGAGCAACTCCGAGTATGATCCCGCTTCCGGCGAAGATAGCGCCAGCGAAACGTCGGAGCCGGAAGATCAGCTCTACGGGGAGTTCTACTGCAACGAGTGCGGCATCTCCTTCCATCGCCAGGATTTACTGCGACGCCATGCCAAGCAGCATTTCAAGCAGCAGGATCATCATTCGACGGTGGCGGCAGGCGACGGCAGCTCCTCGGACGTCATAGCTAGCGGGGATCAGGCCAAAGAGGGTAATGACGGCCACTGTTGTCAAACGTGCGGTAAATCATTTCCAAGTGCCGCGGAGATGCTTTCCCACGCCGAAATCCATGCGAGGTTTCCTCCCTTCAAGTGCGTTCTTTGCGGCATAAGTTTCTACGAGGAGCAGGCCATCAAGCGGCACCTGCACGCCCGCCATCCCAACGAACTGAAGGCCAACTCCTGTGTGCTATGCGGCAAGGAGTGTCGCGACCGCAAGGCCCTGATAAAACATGCCTGGGATCACTCCCGCGAGAAGTGCCACTCCTGCTCCAAGTGCGGCAAGAACTTTCACAATAAGGCGCGACTGAAGCGGCACATGGCCTCCCACAGGGACAAGTCCGTGGTGTGCGAGGTCTGCCAAGAGGAGTTCCCCGACGGACGTACGTTATCTAATCACCGTCACTCGCATAGCACCACGTCGCCGGGCAAACTGTTTCCTTGTCACGAATGCGGCAAGACATTCGGATCACGCAGTTCCCAGCAGATCCACGTCCGCATCCATACGGGTGAGCGTCCCTATGGCTGTCGCTACTGCTGGAAAGCCTTTGCCGATGGCGGAACGTTGCGCAAGCACGAGCGGATCCATACGGGGGAGAAGCCCTACGCCTGTTCCGTGTGTCCGCGTGCCTTCAATCAGCGGGTGGTGTTGCGCGAGCACATCCGTTCCCACCACTCTGGACTGGATGGGGCGAGAAATACCTACCACTGCACAGTGTGCTCGGAGGATCTGGCATCCTCCAATGACCTCATACAGCACCTCATCCAGCACAGTGATTCGAACACCGCCAAACAGCGTCAACCAGTGaCGGGCCCGCGAAAGTATAAGCGTCGACGCAAGCTGCAGCCACACGAGATCGCACACATGCGGGCGGAACACAAGGATGCCAATGGCGGCGGCGACGAGGAGGAGATTTTGGGTGCCGAAGGCAATGGCGATGGTGATGAGTATGCCAGCGATATCGACCTTTGCGACTTTGATGTGGAGAATGTGGACGATCTTTTTGAAATGGCCGAGTCGTCGCCCAAAAAAGAGAAGCGCAAGAGGGCATCGGCGACATCTGTAAAGACAGAACAAAAACCTATTTCCAATGGCGGCGGATCAGCGGTGAAGCCTGTCCAGGAGAAGAACAAGGCCAAGCTGCGATATGACTCCACCAGCAGTCAGCAATCGGATCGAATTTGGGAGGAGAAGTTCCTGCAGGACAGCCAGGTTTCGCTCTTTCAAATCGATTCGCTGGTGGTGGTCAACGATACACATCTGCAGCCCGCTAGCTCAGCGGCCATGCCCAAGACGAGAGGTGGcgccaagcagcagcagcagcaggccaagCAGCCCGTTGAAAGAGCTAGCAACTCCAATCCCTCGGCTGCAAGCTCAGTTGGCACATCATCGGCCTCCGCCTCTGCCTCTACATCCACTTCCAGCAGTCGTAGCAGGAAGAAGACGGCAGCCGCTAAAACGGCTGCTGCCTCGCGACCCCGGATGATTCACACAGAGAAGACCAAGGTGCCGGCCAAGGAAACTGCCGGCGGGGAGTTGGCCAAGAAGACTCGCTCCAAGACCTACATCACCCGCACGGAGACGAGCAATCTGGGCAGTCTGGACAAGTCGCGCAGCCGAGCCTCCAACATCGTGGATGACTACGAAATCATTTCACCGGCTACCCATCCTCCCAACCAGATCAGCTCCAGTCCCCTGCACATcaagcaggaacaggagcagcagcaccgTGTCCCGATGATGTACGACGACAATCTCCTGATAGACGCTGCCCTGCTGCGGGAAAAAACCTACGAGAAGTTCAACCCGAGCATTGTGAATGATCTGGAGGAGATCCTGCGCTCGCCGCTTAAGCACGAGCGCAACACCCGCCTGCGATTCACCAGCGAATCCTCGACCACGCCACAGTTTTTGCCCGAAGAAGAGCAGAATCTGATTAAGATCGAGCCCACGTCTCCAGATTTGCGGGAGATGCTGGAGAGTCAGAGTCAAAGGGTCAGGGTACCAAGTGGCAACACACCGTCGACCTCGTCTTCCTCCGCCGCCAGAACTTCTCGTCATCGTATGATCACAGCCAGTGGACCAAGAGCAGGGAACAAGAGAGGAGCAGGCAGTGGTAGCAGCGCTAGCAAATCTTCACCTGCCCCGGGAGTAATGGCCAAGAAAGTGAGCACTGCTGCCAGTAAGGTCGGCGGCTCGTCCTCGTACCTTAATTACGGTGTGGATGCCTACAATGTAAGTGTACCTGCCAGCGCCAGCACTGCCGATGTGGGCAGCGGATTCTTTTCCATCTCTGAGGTCGTATCGGCCGCCGATGCTGCTGATGCGGCGGCCAAGGCGGCTGCGGCCGGGAAACCGGAGCGAAAAACGCGCAGTTTCGAGTGCGAAATGTGCTCGGCCATCTTTTACGATCGAGCCCAGTTACTGGACCATGTGCACATCCACATCTAG
Protein Sequence: MNNQDYGGIQWIQHHPAAGDSSETDIMEHEDADGDDMVSGADGDPDGDGDADVDLDHMAAENLIFMARDGQLGEIIAANEGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAAAAVSGSSSIKFENQSHRQTDDHYYEQEWPLYQQQHQQQEQEQQQELGQHEQMLQQEQQQLVCNSEVQFVASYTASVAPPPAPSRGRISRLKPKEESSQFIVITDKPAPSELRDYMASEPVPQPVVPTSQPMAIDAPPAPQPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQDHQKTHQFEESNSEYDPASGEDSASETSEPEDQLYGEFYCNECGISFHRQDLLRRHAKQHFKQQDHHSTVAAGDGSSSDVIASGDQAKEGNDGHCCQTCGKSFPSAAEMLSHAEIHARFPPFKCVLCGISFYEEQAIKRHLHARHPNELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDGARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKDANGGGDEEEILGAEGNGDGDEYASDIDLCDFDVENVDDLFEMAESSPKKEKRKRASATSVKTEQKPISNGGGSAVKPVQEKNKAKLRYDSTSSQQSDRIWEEKFLQDSQVSLFQIDSLVVVNDTHLQPASSAAMPKTRGGAKQQQQQAKQPVERASNSNPSAASSVGTSSASASASTSTSSSRSRKKTAAAKTAAASRPRMIHTEKTKVPAKETAGGELAKKTRSKTYITRTETSNLGSLDKSRSRASNIVDDYEIISPATHPPNQISSSPLHIKQEQEQQHRVPMMYDDNLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHERNTRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMLESQSQRVRVPSGNTPSTSSSSAARTSRHRMITASGPRAGNKRGAGSGSSASKSSPAPGVMAKKVSTAASKVGGSSSYLNYGVDAYNVSVPASASTADVGSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480304;
90% Identity: iTF_00617778;
80% Identity: -