Dkik013622.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kikkawai
Gene Symbol
-
Assembly
GCA_018152535.1
Location
NW:18501938-18503750[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 3.6e-06 0.00022 21.2 1.5 1 23 182 204 182 204 0.98
2 12 0.0014 0.082 13.1 8.2 1 23 210 232 210 232 0.96
3 12 4.8e-06 0.00029 20.9 4.6 1 23 238 260 238 260 0.99
4 12 1.2e-07 7.2e-06 25.9 3.3 1 23 266 288 266 288 0.99
5 12 4.2e-08 2.5e-06 27.3 2.2 1 23 294 316 294 316 0.99
6 12 1.3e-06 7.6e-05 22.7 0.9 1 23 322 344 322 344 0.98
7 12 1.8e-05 0.0011 19.0 3.5 1 23 350 372 350 372 0.99
8 12 1.6e-06 9.7e-05 22.3 3.4 1 23 378 400 378 400 0.99
9 12 5.4e-07 3.2e-05 23.8 0.4 1 23 406 428 406 428 0.97
10 12 5.7e-07 3.4e-05 23.8 1.4 1 23 434 456 434 456 0.99
11 12 0.00039 0.023 14.8 3.5 1 23 462 484 462 484 0.99
12 12 6.9e-08 4.1e-06 26.7 0.7 1 23 490 513 490 513 0.97

Sequence Information

Coding Sequence
ATGGAGGGTTCGGAACTCACATTCCCGAAGGACGGCCAGGCATCCCGTTCACAGTTCAACAACCAAGTCATCATCAAAAAGGAAATTGAAGAATTTGAGCGTGCCGAAGGGGAGGATTCAACTACAGACGGATTCCTAACACAAGTAAAGACAGAAATCATGAAAGAGGAGGATTCACCGGAAAGCGGTGGGATTCACACTTACCAATCGGTTGATCCTGTCAAAAACGAATTCTTCGAAGAGGAGGTACAAGGATCAGGGGCTACGTATACTTACCAGTACATCGATAATGAAGAGAGTGAAGTCACGGAGGAACATGTACCAGAGGAAGAGCCAGATCCATTTAGTGACCTGGTCCCGTGTCAAGTAAAAAACGAACCCATCGATGAAGAACCCGAGTCAGACGACGAAATCGATCAATTTGATTGCCATGTGAAAAGCGAGGAGATGGACGATGACTTACTTGAAGATGAGGAGGATCATAATGATGTCGACAAGCCACAGGAAAGCGAGAAAGATGAGGATAAGTATGCGAATCTCCCGCACAAGTGTCCCCATTGTCCGAAGGGATTCCGGCTCTTGGCTCAGCTCAAAATCCACATCCGAGGTCACACCGGCGACAGTCCACACAAGTGTAAAAACTGCTCCAAGACTTTCGGAACGGCTGCTCACCTTAACAGGCACTGTCGATCCCACACCGGAGAACGACCCTTCGAGTGCACCCACTGTCAGAAGGCCTTCACAGCTCTGTATCATCTCAAGGTGCATCTGCGCACCCACACGGGCGAGCGGCCGTACCAGTGCCCCCACTGCCCAAAGACTTGTATAGTGAAGGATAACCTCCGGAACCATATCCGCACCCATTTCGAGGAGAGACCGTTCCAGTGTCCGCAATGCCCGAAAGCCTTCAAGGTGAAGCACAACCTCAAAATGCATATACGAACCCACTCGGGCGAGAAGCCGTTCAGTTGTCCCCACTGCTCCAAGGCCTTCACAGGTGAACCGTATCTCAAAGTTCACATTCGGACGCATACGGGCGAAAAGCCGTACAGTTGTTCCCTCTGCCCTAAGTCGTTCATCAACAGGCAGTGCCTGCAGGTCCATTTCCGCACCCACTCCGGCGAGCGTCCGTACAAGTGCACCCACTGTCCCAAATCCTTTGCCAAACACTCCGGGCTAACCGAGCATGTCCGGATCCACACGGGTGAACGACCGTACGACTGTTCCGCCTGCCCCAAGGCATTCATAACCAACCAGGATCTGAAGCGGCACATGAGAATGCACACGGGAGAGCGCCCCTTCAAGTGTACCCTCTGTCCCAGTTCGTATACCCAAAACTACTCCCTTCAGGCGCATATGCGAACGCACTCGGGAGAAAGGCCTTACAAGTGCACCGAGTGCCCCAAGGATTTCCAGTACCAAACCAGTCTGGAGTGCCACATGCAGACCCACTTTGGAGTAAGACCCTACCAGTGCACTGAGTGCACAAAGACCTTCGTAACGAGCTCAAATCTGGCGCGGCACGTCAAGAATGCGCACTGGACCTGA
Protein Sequence
MEGSELTFPKDGQASRSQFNNQVIIKKEIEEFERAEGEDSTTDGFLTQVKTEIMKEEDSPESGGIHTYQSVDPVKNEFFEEEVQGSGATYTYQYIDNEESEVTEEHVPEEEPDPFSDLVPCQVKNEPIDEEPESDDEIDQFDCHVKSEEMDDDLLEDEEDHNDVDKPQESEKDEDKYANLPHKCPHCPKGFRLLAQLKIHIRGHTGDSPHKCKNCSKTFGTAAHLNRHCRSHTGERPFECTHCQKAFTALYHLKVHLRTHTGERPYQCPHCPKTCIVKDNLRNHIRTHFEERPFQCPQCPKAFKVKHNLKMHIRTHSGEKPFSCPHCSKAFTGEPYLKVHIRTHTGEKPYSCSLCPKSFINRQCLQVHFRTHSGERPYKCTHCPKSFAKHSGLTEHVRIHTGERPYDCSACPKAFITNQDLKRHMRMHTGERPFKCTLCPSSYTQNYSLQAHMRTHSGERPYKCTECPKDFQYQTSLECHMQTHFGVRPYQCTECTKTFVTSSNLARHVKNAHWT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485270;
90% Identity
-
80% Identity
-