Dkik002533.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kikkawai
Gene Symbol
-
Assembly
GCA_018152535.1
Location
NW:28403870-28406121[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 4e-06 0.00024 21.1 4.9 1 23 99 121 99 121 0.98
2 13 8.2e-06 0.00049 20.1 1.9 1 23 127 149 127 149 0.99
3 13 3.8e-05 0.0022 18.0 3.9 1 23 155 177 155 177 0.99
4 13 1.2e-06 7.4e-05 22.7 6.5 1 23 183 205 183 205 0.98
5 13 6.1e-06 0.00037 20.5 3.6 1 23 211 233 211 233 0.99
6 13 6.1e-08 3.6e-06 26.8 3.1 1 23 241 263 241 263 0.98
7 13 5.1e-08 3.1e-06 27.1 4.2 1 23 269 291 269 291 0.99
8 13 4.4e-05 0.0026 17.8 3.4 1 23 297 319 297 319 0.99
9 13 0.00083 0.05 13.8 7.6 1 23 325 347 325 347 0.98
10 13 1.1e-05 0.00065 19.7 1.1 1 23 353 376 353 376 0.95
11 13 5.3e-06 0.00031 20.7 3.1 1 23 382 404 382 404 0.98
12 13 2.6e-07 1.5e-05 24.9 1.7 1 23 410 432 410 432 0.99
13 13 2.6e-08 1.6e-06 28.0 3.0 1 23 438 460 438 460 0.99

Sequence Information

Coding Sequence
ATGGACGTGATAATCTGTCGCTCATGTCTGGACACCTCGCCGGTCATGGTCAATATATTCGACAAAGCACCAGGACTGGAGATCTCCATCGCCGAAATGATATCCCGATGTACGCCTTATAAGATATCCAGAGGGGATGGCCACTACGAAAACATCTGCGAGGACTGCCTAAAATGTGCAAAAACTGCCTTTGAGATACGGCAGACATTGGAGAAGAGCTACCAGGTCTTTCGCCAGTTGAGGAAGGATAAAGAGAAATCGGACGACCCCAAGCCTTCTTCGGTGAAGAAATCTTACAAGTGTAAGCAGTGCTCCAAGTCGTTCTCCAAGAAAAGCACCCTCAAGACACACAGCCTAACTCACACCGGAGAGCGAACGTACAAGTGCGAGCAGTGCTCAAAGATGTTTTTCAATGCAAGGGGACTCAGGGAACACACTCGAACTCACGCAGAAGAGCGACCCTATGAGTGCTCCCACTGCTCCAAGTCATTCCTGCAGAAAAGTCGTCTCAATGTACACCTGCGGACCCACACTGGAGAGCGACCGCATAAGTGTTCTCAGTGCTCAAAGTCATTTTCCCAGAAGAATCACCTCCAAGTTCACATGTTAACCCACACGGGAGAGCGTCCGTTCAAGTGTTCGCACTGCTCCAAGACGTTTTCCCTTGACTGGAATCTCCGAAAGCACATCCTAACTCACGATGGAGAGATGTCTCGCACTCACAAGTGCACCCAGTGCCCCAAGTCGTTTATCGAGAAAGTAAATCTCCAGAGACACATGCGAACACACACAGAAGAGCGGCCGTTTAAGTGCTCCCATTGCTCGCAGTCCTTTTCTCAGAAAAGTAATCTTCAGTCCCACATCCGCATCCACACGGGAGAACGACCGTTCAAGTGCTCCGAGTGCTCCAAGTCGTTTCTCCGGAAGGAGCATCTGATATCACACGGCAGAACCCACATGGAGGAGGGACCGCATAAGTGCAAGCACTGCCTGAAGAGATTCTTCAAGAAGGATGAGCTCAAGGAGCACGGCCGAACGCACACCAAGGAGCGGCCGTTCAAGTGTTCACAGTGCTCGATGACGTTTACCTATAAGCCAAATCTTCAGGCGCACATCACATACATCCACAAGGGAGAGCGACCGCACAAGTGCGACCAGTGCTCAAAGGCGTTTCCCAATAGATTCACACTTCGGGGCCACATGCGAACTCATACTGGCGAGAAGCCCTACAAGTGCTCGCAGTGCCCGAAGGCGTTTGCCCAGAAGAGCACCCTCACGACCCACAACCGAACGCACACGGGAGAGCGACCATTcaagtgttcccactgctcGAAGACCTTTGCCCAAAAAGGTAATCTTCAGGACCACATGCGAGTACACGAAAAAGCGAAGGAATAG
Protein Sequence
MDVIICRSCLDTSPVMVNIFDKAPGLEISIAEMISRCTPYKISRGDGHYENICEDCLKCAKTAFEIRQTLEKSYQVFRQLRKDKEKSDDPKPSSVKKSYKCKQCSKSFSKKSTLKTHSLTHTGERTYKCEQCSKMFFNARGLREHTRTHAEERPYECSHCSKSFLQKSRLNVHLRTHTGERPHKCSQCSKSFSQKNHLQVHMLTHTGERPFKCSHCSKTFSLDWNLRKHILTHDGEMSRTHKCTQCPKSFIEKVNLQRHMRTHTEERPFKCSHCSQSFSQKSNLQSHIRIHTGERPFKCSECSKSFLRKEHLISHGRTHMEEGPHKCKHCLKRFFKKDELKEHGRTHTKERPFKCSQCSMTFTYKPNLQAHITYIHKGERPHKCDQCSKAFPNRFTLRGHMRTHTGEKPYKCSQCPKAFAQKSTLTTHNRTHTGERPFKCSHCSKTFAQKGNLQDHMRVHEKAKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-