Basic Information

Insect: Drosophila kanekoi
Gene Symbol: PRDM1
Assembly: GCA_037075305.1
Location: JBAMCE010000141.1:4023568-4028095[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.3e-05 0.0022 18.4 2.5 1 23 907 929 907 929 0.99

2 5 9.9e-06 0.00066 20.1 5.1 1 23 935 957 935 957 0.98

3 5 2.1e-06 0.00014 22.2 4.3 1 23 963 985 963 985 0.98

4 5 0.00069 0.046 14.3 2.4 1 23 991 1013 991 1013 0.97

5 5 0.00012 0.0078 16.7 0.1 1 22 1019 1040 1019 1040 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.3e-05	0.0022	18.4	2.5	1	23	907	929	907	929	0.99
2	5	9.9e-06	0.00066	20.1	5.1	1	23	935	957	935	957	0.98
3	5	2.1e-06	0.00014	22.2	4.3	1	23	963	985	963	985	0.98
4	5	0.00069	0.046	14.3	2.4	1	23	991	1013	991	1013	0.97
5	5	0.00012	0.0078	16.7	0.1	1	22	1019	1040	1019	1040	0.96

Sequence Information

Coding Sequence: atgcatggacatcatcatcatcaacagcagcagccgcagcagcagcagcagcagcaggcattgccgccgccgcaacaagtgcaacaaatgTCCGCCACAATGAAGCTGGCCGGCagtccacagcagcagcagcaacaacaacagcagcagcagcagcaacaacaaacacacatagccatacagcaacagcatccgCATCCACATCAACATGCACATCCGCACCATCATCATGCACAGCATCCACATCATCATGCAAAGCTGCTGCGGCGCTcgcgcagtcgcagtcgcagtccaaCGCCGGATGGCACACAGGATTACGATGTGACGCGCATGCGCGAGGAGGACTTTGAGCGTCTGGCCGTATATCTGGTGCCCGACGTGCAGGCGGAGCGCGGCCTGCCCAATCGTGCGGATAAGACGTTGCCGCGCAGCCTGACGCTCAAGTCCTCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTCATACCGCGCGGCACACGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGTTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGatgatgattattattatctgGATGGCTCGGATCGTTCCCAATCGAATTGGATGCGCTATGTGGCCTCGGCGTACAGCTTGTCTGTCATGAATCTGGTTGCGTGCCAGCATCAGGAGAACATATATTTCTATACCACCCGCGACATATTGCCCAACGAGGAGCTGATGGTCTGGTATTGCAAGGACTTTGCCAGCCGCTTGGGCTACGATGTGGATCCGGAGCGCACCATATTCGGTGCCTGCAAGCAGGACGTGgatgtggaggaggaggaggatgaggacGAGGAGCTGGCGCACAAGAAGCCACATTATGCAATGGCCGCACCTGAAATACCCGCCGAGGTGGCTGTCAGTCACATTACCTATGTCATGGGTCTCCATTTGCCAGGTGCGccgccggcagcagctgctcctccgccaacagcaacaacaacagctgcccaATGCTGTCGACGCGCCAGTCCGCCTGCCCATGtcagcaccaccagcaacaacaacaacaatagcagcagctccaACTCGCTGCATCCGCATATTCAGCACAGCCGACACGCGTCCGTGATCATTGGGCAGGACCGTTCGCCGctaaccagcagcagctgcgacaagGAGACGGCTGGATCGCCGCTGTGCGGCAAGGATGCCCACTATGAGCATCAGCTGACGCCGCAGGATGGCAGCGTGCGATCGGTGCGCTCCGATGAGGGCTACCACAGCAATGAGTGCCAGGAGGATGGCCTGACGCCGCCAGAAGATTCCAGCGACAGCGAGAGCGAGCACAACTATGTGCTCGACTGCTCCAAGAAGGCGATTGCGCCCAAGGAGACAGTCATTGCGCAGGCGCAAAAGCCCAGCAGTGTGACGCCGCCAGCCACCACGCCCACtgtcgccgccgtcgccaCGCCCAGCTGTGAGTCGGACAAGAACGAGTTTCGCAAATTCAAGGTGAAAATGCCGCTGAAATACGagttcaaaaacaaaagctgtgTGAAAACGGAACCGCTAAAGGATGTCGATGAGCATCTGCCGCCAGCCGGCGTCAGcttggaggaggaggagctgcacGAACTGcatgcggcagcggcggcggcggcagcagcggcagcggcagcgcattCCGAGGATTCGGTGTGTCCGCCCAGCACCACCACAACGCTAGGCGAGGAGCAGCACCACCATCAGCAGCATCTGGAGCCAACCAACACACAGCCCGCCTCCTCGACGGTAATTGTGCTGGAGCACAACTCGAGCGGCCAGACGCGCACCATTGTGCCGCTGAGCAAGCCCTACTATGAGGCCGATCCGCCTGGTGAGCGATATGTGCGCTTCACTCAGCCCAGCTCGAGCATACTGGAAACCATACTGACCAGCCAGCATCGTCTGGAAGCAGCTGCCGCGGCAGCCAATGCCTGCAGGCAGGCGAACGCAGCGACGCCGCCGCCCACCTCGCCCACGGAGATGGCCTACAGCTACAAGAAGTCGCAGCGCTATGGCAATGCAGTCAGTCCCGATTCCAGCTCCAATCTGGGTCAGCCCCAGGAGCTGAGCGGCGCGCACATTGTGAGCGAGCAGGAGCTCAGCTTGAGCCGCGCCACGCTGATCAAAGGCGAGTGCTCGCCGCCACCCGCCGCCTCGCATCATCATCACAATGTCATTTATTCGCCGTCGAGGACACATCATGCTGCCTACGAGCCGGGCAGCCATTCGCCCAGCTATGCCGGCTATGCGGGCTATCCGGGCGCGCAGTCCCTGCATGCGGCCACCTCCACGTTCCACTCACCGCCGCACAGCTCGCACTCGCCCTTCGATCGCCAGTCAAACGCGTCCAGCGGCGGCGGTTCCGCCTCCAATTTGCATCTGCTGCAGAGCAGCACCCAAATGCTGAACCATCCGCTGATGCAGCCACTGACACCGCTGCAGCGTCTTTCACCGCTGCGCATCTCGCCGCCCAGCAGCCTCAGCCCGGATGGCAATTCGTGTCCGCGCAGCGGCAGCCCTCTGAGTCCCAATTCGTTGGCCTCGCGCGGCTACCGCTCACTGCCGTATCCGCTGAAGAAGAAGGATGGCAAAATGCATTACGAGTGCAATGTGTGCTGCAAGACCTTTGGTCAGCTGAGCAATCTCAAGGTGCATCTGCGCACTCATTCCGGTGAGCGGCCGTTCAAGTGCAATGTCTGCACGAAGAGCTTCACCCAGCTGGCGCATCTGCAGAAGCACCATCTGGTGCACACGGGCGAGAAGCCGCATCAATGTGACATCTGCAAGAAGCGCTTCTCCAGCACGTCCAATCTGAAGACTCATCTGCGGCTGCACAGCGGCCAGAAGCCGTACGCCTGCGATCTCTGCCCGCAGAAGTTTACGCAATTCGTCCATCTGAAGCTGCACAAGCGTCTCCACACCAACGATCGGCCCTATGTGTGCCAGGGCTGTGACAAGAAGTACATCAGCGCCTCCGGCCTGCGCACGCACTGGAAGACCACAAGCTGCAAGCCCAACAATCTGGAAGAGGAACTGGccatggcggcggcggccacCTCCGAGTGCCTGGACAAGGACTTGCCGGAGCCGGACTCGCGCGAAGCCtatgagcagctgcagcagcatatGCATCCGGTGCATCCCAGTCTGCGTCATTTGGCCGGCGCCCAGTCGCCGCCGCGTCTCATTCCACTGGGCGGCAATGGACAGccgcacatgcacatacagcagctgcagggccACCAGCCGCATGCGCAGGCGAGCAATGCGCCGCCGGGCCACCTAATGCATTCGCCGCACGGCGGCCCGCCCATGCTGCTGACCACAGCCAatcagctgccgccgccaacaACGCCACAccacatgcaacagcagcaacagcagcagccgccacagGCGTCGCCCGGCCGACAGCCGCCCacgcatcagcaacagcagcagcagcaacaacagcagcagcaacagcatctggGGCCTCCGCATCATCTGGCACAGCACTCGCCCAAGTCGCTGAAGCCGCTGCCGGACGCTGGCTATCTGCATGGGCCGCTCGTGCAGACGCAGGAGAATCGACCCTCGGTCATCGAGTCCTCCAGCCAGCCCATGATCATTGAGTGCACGTAG
Protein Sequence: MHGHHHHQQQQPQQQQQQQALPPPQQVQQMSATMKLAGSPQQQQQQQQQQQQQQQTHIAIQQQHPHPHQHAHPHHHHAQHPHHHAKLLRRSRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVEEEEDEDEELAHKKPHYAMAAPEIPAEVAVSHITYVMGLHLPGAPPAAAAPPPTATTTAAQCCRRASPPAHVSTTSNNNNNSSSSNSLHPHIQHSRHASVIIGQDRSPLTSSSCDKETAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVTPPATTPTVAAVATPSCESDKNEFRKFKVKMPLKYEFKNKSCVKTEPLKDVDEHLPPAGVSLEEEELHELHAAAAAAAAAAAAAHSEDSVCPPSTTTTLGEEQHHHQQHLEPTNTQPASSTVIVLEHNSSGQTRTIVPLSKPYYEADPPGERYVRFTQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQELSGAHIVSEQELSLSRATLIKGECSPPPAASHHHHNVIYSPSRTHHAAYEPGSHSPSYAGYAGYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLQQHMHPVHPSLRHLAGAQSPPRLIPLGGNGQPHMHIQQLQGHQPHAQASNAPPGHLMHSPHGGPPMLLTTANQLPPPTTPHHMQQQQQQQPPQASPGRQPPTHQQQQQQQQQQQQQHLGPPHHLAQHSPKSLKPLPDAGYLHGPLVQTQENRPSVIESSSQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00476868;
80% Identity: -