Basic Information

Insect: Drosophila kanekoi
Gene Symbol: Hivep2_1
Assembly: GCA_037075305.1
Location: JBAMCE010000553.1:2708223-2716264[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0001 0.0068 16.9 0.9 1 23 230 252 230 252 0.98

2 8 0.00031 0.021 15.3 2.8 1 21 258 278 258 282 0.89

3 8 0.011 0.7 10.5 0.2 1 19 909 927 909 930 0.93

4 8 3e-06 0.0002 21.7 2.0 1 23 1660 1682 1660 1682 0.99

5 8 1.3e-05 0.00083 19.7 5.3 1 23 1688 1712 1688 1712 0.92

6 8 0.002 0.13 12.8 2.7 3 23 2198 2218 2197 2218 0.93

7 8 0.00086 0.057 14.0 1.2 1 23 2224 2248 2224 2248 0.91

8 8 0.0027 0.18 12.4 2.7 1 23 2269 2293 2269 2293 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0001	0.0068	16.9	0.9	1	23	230	252	230	252	0.98
2	8	0.00031	0.021	15.3	2.8	1	21	258	278	258	282	0.89
3	8	0.011	0.7	10.5	0.2	1	19	909	927	909	930	0.93
4	8	3e-06	0.0002	21.7	2.0	1	23	1660	1682	1660	1682	0.99
5	8	1.3e-05	0.00083	19.7	5.3	1	23	1688	1712	1688	1712	0.92
6	8	0.002	0.13	12.8	2.7	3	23	2198	2218	2197	2218	0.93
7	8	0.00086	0.057	14.0	1.2	1	23	2224	2248	2224	2248	0.91
8	8	0.0027	0.18	12.4	2.7	1	23	2269	2293	2269	2293	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCATGTGGCAAGCAGCGCAACGAGCGTGGCCACAACaaccaccagcaacagcaacagcagcaacatcagcagcagcaacatcagcaacaacaacaacagcgatgatgcggccacagcagcagcagcagcaacagtagctGGCGACTGGAAAACTTCAAACAATTTGCGctatttgcacaaaaagttTAAGCGTCTGGCCAGCACCACCGAACCGGAAACGGGCGATGCGCTGCGCACCACATCGCTCTCATCCAACAGCTCGTTgtcaccgccgccgccgctttaTAATGGACATGtgacacaacagcagcagccgcagcagcagcagcagcaggcggggCCTTTGCTGCCGGCTAGCAATGAATTCAGTGCCAATTTCgtaaatgccaacaacaacaacagccatgatgagagcaacaacaatagtaaaaatattgctgttgctggtgcgcCCAGAACACGGACACCGcttagcaacagcagcaacatcagcaacaacagcaactatgCCAGCAATGCGACACTGTCGCCAGCAACATTCgcacagcatcagcaacagacgcagccaacaacagcagcaacaacaaccacaacagcggcaactgccacaccaccagcagcaacagcaacaacaacggcaacaacagcaacaggtcTGGCCGAGAAAATGGGTCGTTATGTCTGCCCGTATTGCAATCTGAACTGTACAAAGCCCTCGGTGCTGCAGAAGCACATACGTGCCCATACCAATGAGCGGCCGTACCCGTGCGAGACCTGCGGCATTGCCTTCAAAACGAAGAGCAATCTCTACAAACACTGCCGTTCACGTTCCCATGCGGCGCGCGTGCGCGGTTTCGATGTGCCCGCCCACGAGGCGGACGGACTCTCCGATCAGGATGGCGACGGGGAGCTGAGCAACAGTAGTTCCGAGCTGTTGAGCTTGGAAGTTCTGAGCCGTGCGGATTCGCCATATGACGAGCCCATGGCCTCGCCTACGCCCTCGCCATCCACGCTGTCCGCCGCGAAGAGCGCGTACTTGCAACAGCCGCCACTGCCGCAGCAcatgcaacagttgccgctggGATCGCCCGCTGCCGGAACACTGCCGCCCGCCACAGCCGATACGCTGCACTCGGCGACAGCGCAGCATCGCCAGTCGATTGACTACAAGCCGTACAAACCCAAGTTTCACAATGCGGCGCTCTACGCGCCCGGCAGCAgcaaagagcaacagcagcaacagcaacaacagcaacaacaacagcaacagcagcaactgcaacaacaaaagctgcccCCGCCGCAGCCAACGCTGGTGCATCCCACGCTCTCGCTGAGCACACAGCTGAAGCTCAACAATCACATCAACTCGCATCAGGTGCAGTTGCAGCgacagctccagcagcaacagcagcagcaacaacaccaacagcaacagcagcagcagcaacaatcgcTGCTGATGGCTGCCGCAAATCCTGCTAATCCCGTTGTACTGCCCGCTTtggtgccgccgccgcaactGCCCACGGGCGTCTATTATATGGGACAGCCGCAGTATTATAatccaactgcagctgcaatacATCAACATGCGCTCGCCATGCAGTTCCAGCAGCactttcagctgcagcagcagcagcatcaacagttccagcagcagcagcaacaccatcaacagcagcaacagcagcagcaacactcgCCGTTGCTGAAGGcgccccaacagcagcagcaacagccgcagcaaacACCGCCGCccccgcagcagcaacagCTGGTGCGCTCCAATAGTCAAcaggcagcgacaacagcgacccctgccacgcccacgcccacagccaATCTGGGCAGCTttgccagcggcagcggcggcatgCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCGAAGCTGATCTCACAGAACGAGGCCATAGTCGAAAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAGTCGCTCGCGAAGCTtcaacaatgccaacaacaacaacagcggcaacaacaacaacaacagcagcagcaacagcagcaatcagacggccaacagcagcaacagcagcagcagcggcaacagtcaGCAGCTGGGCGAGACAAAGGTGAATCTGGCACAGGCCATAGTGctcaaacagcagcagcagcagcaacaacagcaacagcagcagctgcaacaacagctgcaacagcagcaacaataccaAATGtacatgcaacagcagcagctgatgcagcTAGAGAGTGTCAATGGACTGCTCAagcgtagcagcagcagcagcggcagcgccgcCTATCCAGGACTcaaagccacgcccacgctgCCAGCAACGCCCACGACGAATGTGAAGCTGCAAcaactgccgccgccgccgtcgccttTGCCGCTGCAAACGCTGCAATATCGTCAGGATCCCGCAACGCCGGTGCCCAAgctagagcagcagcagcaaccgctcAATCACTCCCAGCCCCTAAATCTGTCCGCCAAACCGAAGCTAGCGATGCCCCcaaaaccagcagcaacagcaacaggaacaacagcagcaacagcaactgttgctgccgtgcCGAAGAGctcagcaactgctgctgcggcgccgCCGAACAATTCAATTATCaagaatttgttgttgaatgCGCGCGGCCTGGCCGTGCCCATCGGCGAGGGCGACGATGCCGTCTACTCCTGCCCCATCTGCGCCAACGAATTCCGCAGCGCGGACGAGCTGAAGCACCACAACAGCACCTATTGCCAGGATGCGAACAGCAGTGCGACGATTAGTCCGGCCTCATCGCCCAGCCGGAAATACTTCCGCTCCAACTCCAAGTCGCTCAGCCTGCCAGAGCTCATGTGCGACATGGCCAACTCGAAGAATCCACTCTCCCTCGCCAAGCTCGCCTGGTCGCAGCTCAAGATCAAGCCCAGCACCGTGGTGCTCAGTCGGCTCAGTGCGGCGCAGTCGCCAGCGCGCACCTcgacagcaactgcaacaacaactgcagctgcagtcagcagcagcagcaacaacccgCCAGCAAcagtcacagcagcagctgtcgtAATCCCGCCCAGCATAGATCCCGGCAGCAGCGTCTCGCTGCGCTTTGTGGACGCGCCGCTGCCCTCGCCCGGCCcgctgctgggcaagaccCCGCTGGTGGACTACGCGGCGCCGCGCAAAGCGCCCGATGCCCAGGTGGTCATCACCAAAATGCACGAGGATCGGCTGGAGAACATCATCATTGAATCGCCGCCTGCGAAGCGGCCCAAGCTTAGCGACATTGCCATCGCGAGCAGCCTAAGCGGCAAGGCCTTTGCGCTGCCCGCGGGCGTGCAGCTGTTCCTCGGCGGCAATCAGGAGTTGCCATTGCCGGGCGCCTTTGGCGGCGGCAAGGAGGAGCGTTTGCGTCGATTCACCTCCTCCGGTGGCAGCATGATTCCCATCTCCGAGTGCCCCGAGCTGGACAAGAGTCCCAAAATGATACGCACCCCATTGCTATCGGGCGGCAGCTTCCAGGAGATGTCGCCGCGCCTCAGCGAGACCAAGGAGCGCAAATTGCCGCTGCCCGTGCCTAACAATGGCTATCTgctcgccagcagcagcagcagcaacaacagcaacacgccgcaacattttcagtttcCGCCCATCAGCTCGATAACTGCCTTCAATCCTCTCACGCTGCCGccgatgagcagcagcaacaaccatgTTGCGGATGCCCACAAGCCCATACCGTATGTTCCCGGCATACCGGGTCCGGGTAgcctgtcgctgctgccgccgccaccgcagcagctgcagctgcagccgcgcGGACGCAGTCCCAATCGCAAGCAACCGagtcccaatcccaatccttTGCTGCTGGATGCGCCGTTAAAGGCGCTGTCGCCGTTCGGCGGCGTACAGAATTTGCCCAGCGAATTCAGTCGGCAGCCGCCGACGCCCGCGCAGCGTCAGGCGCTGCAatggagcagcaacaacagcaacagcagcagcagcaacaacaacaagacggcagcaacagttgccgccgtGGACGTGAAGAAGGCGCCCTTCAACTTTCTGCGCATGGCGGACAACgtgaaggagcagcagctggcacagGAGGTGCGACATTTCAATTTCGACAACGTGCACAAGACGCAGGAGGCGCTGGCGCCGCTGCACGTCGACACGCCTGaggaggcagcagcaacatctggaacaacagcagcaacatctgcagcagcagcaacagttgccacgcccagctcGGCCAAGTCGAAATTCCTGCGACCTACCAGCCTGCCGCTCAAGCCGGGCACCTTTACGCCCAAGCGTCATCATGGCATCACGCCGACAGCGAACACCCTGCCCCTGATCTCGCCCGAGACGCCGCGCCCCTCCAAGTCGTGTGTGCAGCTCTATTTGAATGGGCACGCCTACACGTATCTGGGTCTCAAGTCAAGCACAAAGATGTTCTACTGTACAGTGAACTGTCCGCAGCCGTCATATGTCGCGGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCGTTGGGCTTCAAGCCCAGACAGGTGATGGCCCTCTACGATTCCAGGCAGAAAATGCTCGGCTTCGGCTCGACCATGTCGATGGCGGGCACAGGCGCCGGCAAGCTGCACTACGCCCTGGTCAGCTCACAGCAGACgatcagcagctgctcgacgacGGTCAACAACCAGAGCAAGTTCTATCAGCACCAGCCGAAGCAGCCGCCGACCTCGATCGGAGCGCTCAGCGAGGCGAATGTGGCGGCCAAGGCCAGTGAGGAggacgctgccgccgccgccaagaAGCTGGAGTCGGGCCAACTGCTTGTCGGTGGCTATGAATCGCACGAGgattacacatacatacgcggACGTGGACGCGGCCGGTATGTGTGCTCCGAGTGCGGCATCCGATGCAAGAAACCATCCATGCTCAAAAAGCACATTCGCACCCACACGGACGTGCGTCCGTTCACCTGCAGCCATTGCAATTTCAGCTTCAAGACCAAGGGCAATCTGACCAAGCACATGCAGTCTAAGACGCACTTCAAGAAATGCATCGAGCTGGGCATCAATCCTGGTCCCATGCCCGCCGATGGCGAATTtctcgatgtcgatgtcgagtTCGATCAGCAGTCGTCAACATCCGCTGGCGGACGCACCTCATCCATGGCCGGCGAGTCCGATTCGGATGATTACAGCGACAACGAATCCGAGAGCAGCGaCACAGATGAGTCGAAGTCGCGCATGAAGGAGCATGAGGCGGCGCGCGGCCTGCTCTCGCTGTCCATGACACCGCCCATACCGCAAAGCGTATCGCCGTATCCCGCACAACTGCTGGAGGCACCCGGCCCGGCGGCCAGTCCGGCGAACAGCATTGGCTCCTCGGCGGGCAGCGCTGCGGGCGGTTCGCAGCCAAAGCGTCAGGTTTGCTCGTTTACCTCGCCCAAGCCGCCCTTCGACTACCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCGAAGCGTGACGTGCCCAACGACGAGAGCAGCGCGCCCATGGATCTGACCAAGCCGCGTTCCATGCAACACATTCTACCCGcttcatctgctgctgctgctactgcccAGCCGTTGGAGCAGACACTGCCCAAATCGCAGGCACAGCAGATGCGCGATGTGATCTTTGGTGCGGGCAACAACGAAAGCGGCTTCATGAAGACGCTGATTTCGGTGTCCGATAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCAAAGCGCGAGAGCGAAGGCGACGATCTGCTGCTACAGACCTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAGTTCAGTCGCAACTACCTGATGATGACCAgctccaacagcagcaccacctCCGTCACttgcaccaccagcagctcTGCCGGCACGCCcatcgtcagcagcagcagcggaagcCCGCCGAAGCCGGCCATCAGCATCACGGAGCTGCCCAGCATTGAGGTGCACGAGGTGCAGGAGATCCAGGTGAAACCCGAGCCGCCGGCCGTGGTTCAACTGCAGCTGCCCGAGGAGAGCGAGCCATGTGAGGCACAAGCGGAGCGGGAGCAGCCAGCCATAGcagttcctgctgctgctgtatctGTCGCCAAAGGCAGCACGGAGCTAGTCATGCCGCAGCCGTCGACGCCACACAATGCCAATCTGCCCGCTGCAGTGCAGCAGCCGGATGCCACCGATTTTAGCGGTGTGctaagcaacagcaataacagcctGGCAGGAGGCAGTGGATCCGCACGCACTGTCATCGTCGGCGAGGAGGGCTTCAAAGCGACGCCGCCAACGAGCAGCGCACAGGAACTCCAATCCATCCCTGCTGTAGCTGCTCccgctccagctgcagctacagctgctgCCGCGCCTGCACCTGGCAGCTATCCGGGGCGTGTAGTGCCGCCTCCACCGCCGCCAATTGCCAGTGATGCGCGGCCCACGTGCATCATTTGCAGCAAGACGTTCCAGCGGCAGCATCAGCTCACCCTGCACATGAACATACACTATATGGAGCGAAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACACAGGGTCATCTGCAGAAGCACGAACGCTCCGAGGCGCACAAGAACAAGGTGATGATGACGTCCACATTTGGGGTGCCGACCACTTCGAATCCGCGTCCGTTCGAGTGCACAGATTGCAAGATCGCGTTTCGCATACACGGCCATCTGGCCAAGCATTTGCGCTCCAAGACGCACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTCGGCACCTATGCGGAGATCGAACGCGCCGGCATCAGCCTGACCGAGATCGATACCAGCGACTGTGAGAATTCCCTGATATCGCTCAAGCTGCTCGCACAGAAGCTGCTCGAGAAGGATCCGAATAAGCTGAGTGGCTATACAACGCCCTCGGGcatgctgcagctggccaCGGATACGCCAGCCGCCGGCCAGGACAGCGCCAGCGAGGATGGCTTTAGTGCGGCGAACAGTGCCGCGGCCTCGGCCATTGCCTCACTGGACAACGACAGCGCAGGCAATACGCCCAAGCGCGCCAGCTCCATGTCCGAGGATGAGACGCTCACCAACGGCCTGAGCCATGGGCACAGCCTCAAGCGTCGTCGTCTGCCGGgcagcagcttcagcagcaACGGCGACGAGAGCGACAATCCGCCGGAGACGacgggcagcaacagcatcgaGAAGCGTCCGAGGAGCAATACAAATGAATTGTCGCTGCCGGTGGCCACGCCCAGCAACTGA
Protein Sequence: MTLQHVASSATSVATTTTSNSNSSNISSSNISNNNNSDDAATAAAAATVAGDWKTSNNLRYLHKKFKRLASTTEPETGDALRTTSLSSNSSLSPPPPLYNGHVTQQQQPQQQQQQAGPLLPASNEFSANFVNANNNNSHDESNNNSKNIAVAGAPRTRTPLSNSSNISNNSNYASNATLSPATFAQHQQQTQPTTAATTTTTAATATPPAATATTTATTATGLAEKMGRYVCPYCNLNCTKPSVLQKHIRAHTNERPYPCETCGIAFKTKSNLYKHCRSRSHAARVRGFDVPAHEADGLSDQDGDGELSNSSSELLSLEVLSRADSPYDEPMASPTPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPATADTLHSATAQHRQSIDYKPYKPKFHNAALYAPGSSKEQQQQQQQQQQQQQQQQLQQQKLPPPQPTLVHPTLSLSTQLKLNNHINSHQVQLQRQLQQQQQQQQHQQQQQQQQQSLLMAAANPANPVVLPALVPPPQLPTGVYYMGQPQYYNPTAAAIHQHALAMQFQQHFQLQQQQHQQFQQQQQHHQQQQQQQQHSPLLKAPQQQQQQPQQTPPPPQQQQLVRSNSQQAATTATPATPTPTANLGSFASGSGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANNNNSGNNNNNSSSNSSNQTANSSNSSSSGNSQQLGETKVNLAQAIVLKQQQQQQQQQQQQLQQQLQQQQQYQMYMQQQQLMQLESVNGLLKRSSSSSGSAAYPGLKATPTLPATPTTNVKLQQLPPPPSPLPLQTLQYRQDPATPVPKLEQQQQPLNHSQPLNLSAKPKLAMPPKPAATATGTTAATATVAAVPKSSATAAAAPPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDANSSATISPASSPSRKYFRSNSKSLSLPELMCDMANSKNPLSLAKLAWSQLKIKPSTVVLSRLSAAQSPARTSTATATTTAAAVSSSSNNPPATVTAAAVVIPPSIDPGSSVSLRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIIESPPAKRPKLSDIAIASSLSGKAFALPAGVQLFLGGNQELPLPGAFGGGKEERLRRFTSSGGSMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSETKERKLPLPVPNNGYLLASSSSSNNSNTPQHFQFPPISSITAFNPLTLPPMSSSNNHVADAHKPIPYVPGIPGPGSLSLLPPPPQQLQLQPRGRSPNRKQPSPNPNPLLLDAPLKALSPFGGVQNLPSEFSRQPPTPAQRQALQWSSNNSNSSSSNNNKTAATVAAVDVKKAPFNFLRMADNVKEQQLAQEVRHFNFDNVHKTQEALAPLHVDTPEEAAATSGTTAATSAAAATVATPSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKSSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPRQVMALYDSRQKMLGFGSTMSMAGTGAGKLHYALVSSQQTISSCSTTVNNQSKFYQHQPKQPPTSIGALSEANVAAKASEEDAAAAAKKLESGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPAQLLEAPGPAASPANSIGSSAGSAAGGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRDVPNDESSAPMDLTKPRSMQHILPASSAAAATAQPLEQTLPKSQAQQMRDVIFGAGNNESGFMKTLISVSDKVRISAEMEEQAKRESEGDDLLLQTYIKEQALQHAKMKQSQFSRNYLMMTSSNSSTTSVTCTTSSSAGTPIVSSSSGSPPKPAISITELPSIEVHEVQEIQVKPEPPAVVQLQLPEESEPCEAQAEREQPAIAVPAAAVSVAKGSTELVMPQPSTPHNANLPAAVQQPDATDFSGVLSNSNNSLAGGSGSARTVIVGEEGFKATPPTSSAQELQSIPAVAAPAPAAATAAAAPAPGSYPGRVVPPPPPPIASDARPTCIICSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLATDTPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLSHGHSLKRRRLPGSSFSSNGDESDNPPETTGSNSIEKRPRSNTNELSLPVATPSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00617119;
90% Identity: iTF_00506344;
80% Identity: -