Basic Information

Insect: Drosophila kanekoi
Gene Symbol: Kr-h1
Assembly: GCA_037075305.1
Location: JBAMCE010000577.1:10403771-10407943[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0047 0.31 11.7 3.0 1 23 208 230 208 230 0.98

2 8 2e-06 0.00013 22.3 0.5 1 23 290 312 290 312 0.99

3 8 2.4e-05 0.0016 18.9 2.3 1 23 318 340 318 340 0.98

4 8 4.6e-06 0.0003 21.1 3.1 1 23 346 368 346 368 0.99

5 8 3.8e-07 2.5e-05 24.5 1.3 1 23 374 396 374 396 0.98

6 8 0.00013 0.0087 16.5 1.4 1 23 402 426 402 426 0.99

7 8 0.68 45 4.8 3.7 1 23 432 454 432 454 0.94

8 8 1e-06 6.9e-05 23.1 0.6 1 23 460 482 460 482 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0047	0.31	11.7	3.0	1	23	208	230	208	230	0.98
2	8	2e-06	0.00013	22.3	0.5	1	23	290	312	290	312	0.99
3	8	2.4e-05	0.0016	18.9	2.3	1	23	318	340	318	340	0.98
4	8	4.6e-06	0.0003	21.1	3.1	1	23	346	368	346	368	0.99
5	8	3.8e-07	2.5e-05	24.5	1.3	1	23	374	396	374	396	0.98
6	8	0.00013	0.0087	16.5	1.4	1	23	402	426	402	426	0.99
7	8	0.68	45	4.8	3.7	1	23	432	454	432	454	0.94
8	8	1e-06	6.9e-05	23.1	0.6	1	23	460	482	460	482	0.98

Sequence Information

Coding Sequence: ATGTCGGAACGGGCCAATGAGAAAAAGACTTGGGGGACCAAGCAAAATTGGATTAAGGATGCACTTAACAAATCCGGCACGGAACTACTCGATGTATCCAAAACTAAGGCTAAGGTAGCGCCAAAgaaagcaaatggcaaagATTCATCCACAACCAACATGGTCTACTATCCCGCTAATCAGCTGCTTATAAAGACGGAGCAGCCCAGTCAGTCGCAATTCTGCCTGCAGACGCCACTTACCGCAACGAGCGGTGGCGGCATTGGTGTTGCGCCACCTGGCGGTCAGCATGAGCACTACGAGCTGTTGCAGACGCCGCAGCAGCGAcagttgcaacagctgcagcagcaacaacaacaacagcaacagcagcagcaacaacaacaacaacagcaacttgcCAGCTATCAATTGgtcctgcaacaacaacaacaacaacaacaacaacatgaaagtattacaacaacaacagcagcaacaacagcagcggcggcagcggctgcagcagcaacaacatccacACAGCAGCGCATCAAAACAGAGCTGCCCTTGGCCTATGGCTCAGCTGCGACCACGAAAACGGTTGCCACGCCCCGCAAGCCCAACATCAACAAGCCGCAGTTCAAGTGCGAGCAGTGCGGCATGACCTTTGGCAGCAAATCGGCGCACACCTCGCACACGAAATCGCACGCCAAGAATGCGGATCTCGCACTGGGCCTTAAGGGTGTCGCAAtgggcgccagcagcagctccagcagctcctCCGGCATGCCGCCGATCGAGCTGAACGAGGCGGGCCTGCCGCTCGGCATACCCAAGAGCCCGACCATCAAGCCGCTGGCCAATGTGGCCGCCGGCGCCGATCCCTATCAGTGCAATGTGTGCCAGAAGACATTTGCGGTGCCCGCGCGTTTGATCCGGCACTACAGGACGCACACGGGCGAGCGTCCATTTGAGTGCGAGTTCTGTCACAAGCTGTTTAGTGTTAAGGAGAATCTGCAGGTGCATCGGCGCATCCATACCAAGGAGCGACCGTACAAGTGCGATGTCTGCGAACGTGCCTTTGAGCATTCCGGAAAACTGCATCGCCACATGCGCATCCATACGGGCGAACGGCCGCACAAGTGTTCCGTCTGCGAGAAGACATTCATACAGTCCGGCCAGCTGGTTATCCATATGCGCACGCATACCGGCGAGAAGCCATACAAATGCCCGGAGCCCGGCTGCGGCAAGGGCTTCACCTGCTCCAAACAGCTGAAGGTGCACTCGCGCACCCACACCGGCGAGAAGCCCTACCATTGCGACATCTGCTTCCGTGACTTTGGGTACAATCATGTGCTCAAGCTGCATCGTGTCCAGCATTACGGCGCCAAGTGCTACAAGTGCACCATTTGCGATGAGACCTTCAAGAACAAGAAGGAGATGGAGGCCCACATTAAGGGCCATGCCAATGAGCTGCCCGAGGATGAGGTGGaggccgctgcagcagcagccgcagttgcGGTTGCCTCATCCATAGCCAGCAACTCggagagcagcaacaattcgCCGCCCAGCTCGCCGCCGGCCGTCAAGAAGCCGCGCCAGCCGCGCAGCattaaagcagctgcagcagccgctgctgccgctgtggcagctgccaatGCAGCGCCGCTTTCGCCCAGCTCCGTCTCATCGATATACTCGCCGGCCAGCAGTCAGGCCTCGACGCCGCCACAATATCTGGCCACAACGGCGCCCAACGAGCCGGATGCACTGAGTCACGATAGCGGCGTCGCCAGCGCCCCTCAGCTGCTGTCCAGCTATGCGGACGAGGAGCTGCCCACGGACTTgagcatgcagcagcagccggcgccCCAAATGATCTACTATCAGCCACAGACGAGTATGTCTATAACGTCGCCCAGCCTAGTGGAGCTGCAGCCAAGCACGCCCGCACCTGCGCCCTCCGGCCTTTCGGCGCTGCTGCAGGCGGCCAGCATGGCGCGAGACGAGCACGCCGATGACATTGACAACGACGAGGACGTGCAGGCGGCTGCCTTGCAAATGATGCAGCTGCGACGCGGTCATGCCGCCACGCCACAAGCACAGTCCCAGCCACAGGCACAgccccaatcccaatcccaatcccagccCACGTTGCATGTCAGCGATCTGGCGGCCAACTATGATGACACGCACGAGGCGAACGTGCTCATCGAGCACTTCAAACGCGGCGACTTGGCGCGTCATGGACTGCACAAGGGCTATGTGCCGGTGCCCATGTATGAATCTGCCCTGCCCAATGCGGACATAGTGCGTCGCGTTGAGGCGGCCATTGGACTGCGCTCCAGCACCGAATCGCCGGAGCGCAGCTCCTCGCCCGAAAGCGATTCCCTAATGATGGCCGATCGCAATGTCCTGACCCTGCCGCTGCGCAAGCGCAAGCACTACATGAACGAGGGCGAGGCCAGCAGCGGTTCTGGTGGCAGCAACGGCGCCAATCATAGTGCAACAGGCGGCGTCAACGAGGCGGTGGCAACAATAGCCACAGCACCGAATGCCACAACAGATGTTGCCGCCAATGCTGCCGGCGCCAAGGTGATGCGCATGAGCTCCGTCATCCAGTTTGCCAAGGCCACGTAG
Protein Sequence: MSERANEKKTWGTKQNWIKDALNKSGTELLDVSKTKAKVAPKKANGKDSSTTNMVYYPANQLLIKTEQPSQSQFCLQTPLTATSGGGIGVAPPGGQHEHYELLQTPQQRQLQQLQQQQQQQQQQQQQQQQQQLASYQLVLQQQQQQQQQHESITTTTAATTAAAAAAAAATTSTQQRIKTELPLAYGSAATTKTVATPRKPNINKPQFKCEQCGMTFGSKSAHTSHTKSHAKNADLALGLKGVAMGASSSSSSSSGMPPIELNEAGLPLGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCERAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGAKCYKCTICDETFKNKKEMEAHIKGHANELPEDEVEAAAAAAAVAVASSIASNSESSNNSPPSSPPAVKKPRQPRSIKAAAAAAAAAVAAANAAPLSPSSVSSIYSPASSQASTPPQYLATTAPNEPDALSHDSGVASAPQLLSSYADEELPTDLSMQQQPAPQMIYYQPQTSMSITSPSLVELQPSTPAPAPSGLSALLQAASMARDEHADDIDNDEDVQAAALQMMQLRRGHAATPQAQSQPQAQPQSQSQSQPTLHVSDLAANYDDTHEANVLIEHFKRGDLARHGLHKGYVPVPMYESALPNADIVRRVEAAIGLRSSTESPERSSSPESDSLMMADRNVLTLPLRKRKHYMNEGEASSGSGGSNGANHSATGGVNEAVATIATAPNATTDVAANAAGAKVMRMSSVIQFAKAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508507;
90% Identity: iTF_00617072;
80% Identity: -