Basic Information

Insect: Drosophila kanekoi
Gene Symbol: Znf516
Assembly: GCA_037075305.1
Location: JBAMCE010000066.1:162680-164461[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0005 0.033 14.7 0.5 1 23 240 263 240 263 0.96

2 8 2e-06 0.00013 22.3 1.1 2 23 285 307 284 307 0.93

3 8 0.00015 0.0098 16.4 0.3 2 23 334 354 334 354 0.97

4 8 9.9e-06 0.00066 20.1 0.9 1 23 360 382 360 382 0.98

5 8 9.8e-06 0.00065 20.1 0.9 2 23 389 410 388 410 0.97

6 8 4.9e-08 3.2e-06 27.3 0.8 1 23 416 438 416 438 0.98

7 8 0.021 1.4 9.6 0.9 1 21 444 464 444 468 0.87

8 8 0.039 2.6 8.7 0.1 1 23 516 540 516 540 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0005	0.033	14.7	0.5	1	23	240	263	240	263	0.96
2	8	2e-06	0.00013	22.3	1.1	2	23	285	307	284	307	0.93
3	8	0.00015	0.0098	16.4	0.3	2	23	334	354	334	354	0.97
4	8	9.9e-06	0.00066	20.1	0.9	1	23	360	382	360	382	0.98
5	8	9.8e-06	0.00065	20.1	0.9	2	23	389	410	388	410	0.97
6	8	4.9e-08	3.2e-06	27.3	0.8	1	23	416	438	416	438	0.98
7	8	0.021	1.4	9.6	0.9	1	21	444	464	444	468	0.87
8	8	0.039	2.6	8.7	0.1	1	23	516	540	516	540	0.91

Sequence Information

Coding Sequence: ATGGACAGTAACAAAAATGAGATTCCAATACCAGGTAAAGTCCATATTAATGTTAACGAGCAAACCTGTCGCGTTTGCTTGGAATCTCACGAAACAACATTGAGCCTTCACGATGAAGTTGAGTTTAGTGATCTGAATGTTGAACTGTGGCAGCTGCTAGAAAACGTATCTAATTTGAAGtGCACTTGGAACGAACCCAATCTGCCCACACAGTTGTGTCAGAGCTGCACGCGTCGGCTGATCAGCGCCTACGAGTTTATACGAGAAGTAGAAAGGTCCAATCAAACGCTGCAGGAATTATGCAGTAGTAAGGAGCAGGATCAATCGGCTGAGGATCATGTGGATGTGAATGAGTACGAAGAATTACCGCACCAGGATGTGGACCTGCTGCAATTGGAAGAATGTGAATCCGTGGTTGAGCTGCAAGAGGTGGAGCTGCCGCCTGAAACCCCGGCCTATGAGGAAGCGCCGTATGAGGTAGCGCCGTATGAGGAAGCTACTTATGAAGAACCAACGTTTGAGGAACCAGCCTATGAGGAACCTACATATGAGGAACTGTCTTTTGTGGAACCGCCATCTGAAGAGTTACCCAATAGCGACAACGACTCCTGCGATCTGGTAACTGAGTCTGATGCGGACATAATTTATGATGCCGATCAATCAGAGGATCGTCCCTCGCAGCTAGGAATGCGCCTGGCACATTCACAAAACTTTATGTACAAGTGTGCCAGCTGTCCACGCAtttttgccaaaaacaaatcgcTGTCACGCCACTTTGCAACAGCTCACAGCCAAGCGGCTGATGTAGCGGCTCAGGAGCTGGCTAAAGAGCACAGCAGCAGTGGCGCACTGATCTGCGAACATTGTCCGCGCATATTCAAGCGTCAAGATACACTGCGTAGACACATGATTGCATTTCATCCTGAGGTAGTCGCCGCTAGCGGTTATTCAGAAGATGCCATAATGAGCGTACCACCAAAACGTGCAGCCAAGCGGCGCGAATGCCCCCATTGTGGCATAAGCTTTCCTGTCTCCAGCCTCACCATACATATACGTCGTCACACTGGCGAAAATCCATACAAGTGCGATCAGTGCGACAGGGCATTTCCACGCAGTCAAGATCTTAGTCTGCACAAGCGTCAGCACACCGGAGAGCGCCCGAGCGAATGCAAAATATGCGCCAAGAAGTTCATTTCGCAAAACAAGTTGGCGCGGCACATGCGTCTGCATACTGGCCATCGACCCTACGCTTGCGACAAATGCGATAAGAGTTTTGTGCAATCTAACGATCTGAAGATTCATATGCGCCGGCACACGGGCGAACGACCTTACGCGTGCGGCGTTTGTGGCAAAAGCTTTGTTTGCGGCTCTCTTTTAAACATTCATCGCAATCAGAAGCGACACTATGAGACTGTAAGGGAAGGAGCTGATAGCTTCGATCCTGATCCCTATGAAAATAGTCGCGTGAATAAGCGTCGTGCCGAGGACATTGAACGAATGCGACTGCAGCGAGAGAGcgacacgcacacagctaTTCTGCGGCCATACAACTGCGGCGTGTGTGGGGATAACTTTAAGAGCGGAGCCCTACTTACAATTCATCGCAATAAAATGGCCCACTATGAGATGGGCAACGTGGACTACGGTGATCCCTACGAGCAAAGatacaagcagcagcagcagacgcagcagctccAAATTGTGCAGAACGAAGATTAG
Protein Sequence: MDSNKNEIPIPGKVHINVNEQTCRVCLESHETTLSLHDEVEFSDLNVELWQLLENVSNLKCTWNEPNLPTQLCQSCTRRLISAYEFIREVERSNQTLQELCSSKEQDQSAEDHVDVNEYEELPHQDVDLLQLEECESVVELQEVELPPETPAYEEAPYEVAPYEEATYEEPTFEEPAYEEPTYEELSFVEPPSEELPNSDNDSCDLVTESDADIIYDADQSEDRPSQLGMRLAHSQNFMYKCASCPRIFAKNKSLSRHFATAHSQAADVAAQELAKEHSSSGALICEHCPRIFKRQDTLRRHMIAFHPEVVAASGYSEDAIMSVPPKRAAKRRECPHCGISFPVSSLTIHIRRHTGENPYKCDQCDRAFPRSQDLSLHKRQHTGERPSECKICAKKFISQNKLARHMRLHTGHRPYACDKCDKSFVQSNDLKIHMRRHTGERPYACGVCGKSFVCGSLLNIHRNQKRHYETVREGADSFDPDPYENSRVNKRRAEDIERMRLQRESDTHTAILRPYNCGVCGDNFKSGALLTIHRNKMAHYEMGNVDYGDPYEQRYKQQQQTQQLQIVQNED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534745;
90% Identity: iTF_00534745;
80% Identity: -