Dkan006844.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanekoi
Gene Symbol
-
Assembly
GCA_037075305.1
Location
JBAMCE010000290.1:682204-685131[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 7.8 5.2e+02 1.5 0.2 2 23 114 136 113 136 0.87
2 13 0.0028 0.18 12.4 0.5 2 23 143 165 142 165 0.93
3 13 1e-05 0.00069 20.0 1.9 2 23 179 201 178 201 0.96
4 13 0.22 15 6.4 8.8 2 23 478 499 478 499 0.97
5 13 1.3e-06 8.7e-05 22.8 2.8 1 23 505 528 505 528 0.96
6 13 0.0004 0.026 15.0 0.4 1 23 533 556 533 556 0.96
7 13 0.00016 0.011 16.3 4.6 1 23 574 596 574 596 0.96
8 13 0.00014 0.0091 16.5 1.6 1 23 601 623 601 623 0.98
9 13 3.6e-05 0.0024 18.3 1.7 1 23 629 651 629 651 0.95
10 13 2.6e-05 0.0017 18.8 0.7 1 23 657 679 657 679 0.98
11 13 3.7e-07 2.5e-05 24.5 2.7 3 23 687 707 686 707 0.99
12 13 1.1e-07 7.4e-06 26.2 3.7 1 23 713 735 713 735 0.99
13 13 1.1 71 4.2 6.1 1 19 740 758 740 763 0.89

Sequence Information

Coding Sequence
ATGCCTGACACCTACGGCCAATTCGATGCGGAACGCGTCTGTCGCGTGTGTCTGCGAGAAGTGGGCGAATTTTACTTCATCTACGATGAGGCGCCTGTGGAACAGGGCGCGAACATCGCTCAGATACTTAACGAGTGCACGCGCTACACCTGTGAGCGTTACGACAAGATGCCGCATCATATGTGCGACACCTGCATTAAGGCCGCCTGTCAGGCATATCGTTTCAAACAGGACGCAGAGAAGGCCTATCGCTCGCTTGTGGACATACTGGGGCTCACACCCATTACCAAGCCAAACAGCAGTGATGTGTGCACACAGACGGAGCAGGTGCCGATGTTGCCGTGCGGCATCTGCAACGATAAATTTCTGAACATTCTTGAGTTACGCGTGCATCGCAAGCGGCAGCACATGCACATGGAGGAGCTTAAGTGCAAGCTGTGCGACGAACAATTccagcagctgcgccagctgcggGACCATCTCGTCGTGCAGCATGATCAACACTCGGCATCGCCGTTGCTGCGTCGGCGTCTGGAATGTCGAGTCTGTCAACGAGCCTTCTCGCGACGTGACCATATGCTTCGCCATATGCGCTCTGTGCACAATGCGGATAGCCGGGGTCGGCTGGACCGGACGCTGGCTGAGAAGCATGAAGTGCAATCCAAGGTGGCCTGGCGGCCCATCGATGAGGCGACCATGCATAGCGGTGATGAACTGGAATCGGCTGCCGTTTTATTCAATGACCCTGTGGATATTGAGAACGAAAACAACGAGAGTGGCTATCAATGCCACACTAACCCCATATCAAGCAACGAGGAAGGTGAAGACGAAGACGTACATGCCGAGGCTAAACAGTCGCTCTGGCTGCACATTAAACCAGAACCGGAGCCGGAACTCGAACACAGCCCGGAGAAAATAGGGTCGCAAGTAACTCGCGATAAGCGCAGAAAAAGAACAATTCTTAAATATGCAGCTCACACGGACACGGAGGATGAGAATGAGTGCGTGGACAAACAGAAAACTGCGGCTAGTGCATTGGCGGCTGAGGTAAAAGAGGAGCCATTGGTTACCGGCGGAGAGCAGCAGTTGTCCATTAAGCAGGAGCGGCAACGCGTTGACAGCATCAAAGAGGATGAGGAGTACGATTTGGAGACCGCAACAGCTGACATTTTGCACAGTGCAGATGAGGACGAGGATGGGGAAGAGTTCGGAAATGCGGAGAGTGACATTgatgaagacgacgacgacgacgaagatggagatggagacgAGCCAGATGACGAGCTGGAGACACAGGCCATGCACAAATCTAAGCTGGACCAGGTAGCCCAAGTGGAAATTGTGCGCGAGTATCTGCAGaaaccggcaactggcaagcAGCGACGCCGTCGacgcaaaaaacaaactgaagcGGAACCGAATCCAGAGAATCGCTGCGACATCTGCATGCGTACCTTTTCCCGTCATTGCCATTTGCTGCGCCACAAGTTATCGCATTTGGAAAAGAAGCCGCACAGCTGCCCGCATTGCCCCAAAGCATTTGCGCGCAGCGATCATTTAAAGGCGCACGTGCAGAGCCTGCACGGCAATAAGGAGCACAAATGCGTGCTATGCGATGCGGCGTTCGCCCGCCTCGATGCCCTCGAACGACACAAGATGAGCAAACACAATGGCGAGGGCCTGGACGCCGGCAGCGAGCTAAAGCTGCAAATGAGCGAGCATACCTGCGAATACTGTGCCAAGCGATTCTCCAGCAAAACATATCTGCGCAAGCACACACTGCTCCACACGGAATTCCTCTATGCGTGCAAGAGTTGCGACGAGACATTCAAGGAGCGCCAGCAGTTACGTAGCCACGAGAAGACCCACACCGGCCAGCGTAATTTCCTCTGTTGCATTTGTGGGGACAGTTTTGCTCGCAACGACTATCTGCGCGTCCATATGCGACGACACAATGGCGAGAAGCCATACAAGTGCCGTTACTGCGTCAAGGCGTTTCCACGCGCTACAGATCTTAAGGTCCATGAACGCTATCACACGGGCACAAAACCAAACCTGTGCAACACATGCGGCAAGAGCTTCCATCGCGCCTACAATCTGACCATACATATGCGCACCCATACGGGCGAACGGCCCTACAAGTGCGACCAGTGCCACAAGAGCTTCAGCCAGAGCAATGACTTGAAGGCGCACATCCGACGGCACACTGGCGAGCGCTATAAGTGTCCGCACTGTGATACTTACTTCCTGCAGCTATACCATATGCGCAACCATTGTCTCAGTGCCCACAACCAGCATATTGAGACCAAAACTGGCCGGCTGCAACGCACCGGCCTGCTGGACGAGCCCAATCACTCGCACCTGACCACTGTGGTAATGCCCCCCGCCCGGTTTCAGCAAACTACGACACCAGATACGCATGCTGTGGCCACCGTGACCACGCAATTGCCACAGCCAGCGTCGACTGTGGCTGCTAcaattgccacgcccattctACATTCGCCGGTCACCTACAATACATCGTCGCCAGTATCGGTATCCGTTCCAGTGCCGGATGCAGCCGGATTTGTGGGTACGGCGGCCAATGCAACAGCTACTGCAACGGCGCCCTTTGGTGCATTCAATATAGCGCCCGTTGTAATGGCGCATCTCATGTACAACCATGGGGGAAGTAGCCAGCAGAGCAATGCGAGCGGCAGCGAGGCGGGAAAATAA
Protein Sequence
MPDTYGQFDAERVCRVCLREVGEFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDTCIKAACQAYRFKQDAEKAYRSLVDILGLTPITKPNSSDVCTQTEQVPMLPCGICNDKFLNILELRVHRKRQHMHMEELKCKLCDEQFQQLRQLRDHLVVQHDQHSASPLLRRRLECRVCQRAFSRRDHMLRHMRSVHNADSRGRLDRTLAEKHEVQSKVAWRPIDEATMHSGDELESAAVLFNDPVDIENENNESGYQCHTNPISSNEEGEDEDVHAEAKQSLWLHIKPEPEPELEHSPEKIGSQVTRDKRRKRTILKYAAHTDTEDENECVDKQKTAASALAAEVKEEPLVTGGEQQLSIKQERQRVDSIKEDEEYDLETATADILHSADEDEDGEEFGNAESDIDEDDDDDEDGDGDEPDDELETQAMHKSKLDQVAQVEIVREYLQKPATGKQRRRRRKKQTEAEPNPENRCDICMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARLDALERHKMSKHNGEGLDAGSELKLQMSEHTCEYCAKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCHKSFSQSNDLKAHIRRHTGERYKCPHCDTYFLQLYHMRNHCLSAHNQHIETKTGRLQRTGLLDEPNHSHLTTVVMPPARFQQTTTPDTHAVATVTTQLPQPASTVAATIATPILHSPVTYNTSSPVSVSVPVPDAAGFVGTAANATATATAPFGAFNIAPVVMAHLMYNHGGSSQQSNASGSEAGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00532523;
90% Identity
iTF_00475355;
80% Identity
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