Dkan001062.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanekoi
Gene Symbol
-
Assembly
GCA_037075305.1
Location
JBAMCE010000066.1:734863-739499[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0046 0.31 11.7 2.7 1 23 224 246 224 246 0.97
2 25 0.034 2.3 8.9 1.9 1 23 252 274 252 274 0.97
3 25 3.5 2.3e+02 2.6 2.3 3 20 307 324 305 327 0.93
4 25 0.083 5.5 7.7 1.4 1 23 404 427 404 427 0.92
5 25 0.87 58 4.5 3.4 2 23 438 461 437 461 0.93
6 25 0.35 23 5.7 0.6 1 20 467 486 467 488 0.93
7 25 0.83 55 4.6 2.0 1 23 506 528 506 528 0.98
8 25 0.01 0.69 10.5 2.5 1 23 608 631 608 631 0.94
9 25 0.0061 0.4 11.3 0.1 1 22 638 659 638 659 0.94
10 25 0.0011 0.076 13.6 0.2 2 23 719 740 718 740 0.97
11 25 0.00011 0.0076 16.7 3.9 1 23 748 770 748 770 0.99
12 25 0.043 2.8 8.6 0.8 1 23 918 941 918 941 0.95
13 25 0.0048 0.32 11.6 0.4 2 22 949 969 949 969 0.96
14 25 0.15 9.9 6.9 0.5 1 23 978 1001 978 1001 0.91
15 25 1.2e-05 0.00077 19.8 1.9 1 23 1026 1048 1026 1048 0.97
16 25 0.00015 0.0099 16.4 0.9 1 23 1055 1077 1055 1077 0.98
17 25 0.011 0.74 10.5 0.0 2 21 1104 1123 1103 1124 0.94
18 25 0.043 2.8 8.6 4.0 1 23 1169 1192 1169 1192 0.96
19 25 1.2 80 4.1 0.3 1 23 1229 1252 1229 1252 0.93
20 25 0.0043 0.28 11.8 1.4 1 23 1277 1300 1277 1300 0.97
21 25 1.5e-05 0.00097 19.5 0.1 2 23 1324 1345 1323 1345 0.95
22 25 5e-05 0.0033 17.9 2.9 1 23 1351 1373 1351 1373 0.99
23 25 2.4e-06 0.00016 22.0 2.0 1 23 1379 1401 1379 1401 0.97
24 25 6.2e-08 4.1e-06 27.0 2.4 1 23 1407 1429 1407 1429 0.99
25 25 0.00075 0.049 14.2 0.3 1 21 1435 1455 1435 1459 0.91

Sequence Information

Coding Sequence
ATGTTGCCGACGAATATTTGTCGCACATGCGCGCTACAGAATGACAGTTTGCTCCCGCTAGCAACGCCCACTAATATATATGACAATAAAAGTTTAAGCGACATATTGCACGAATTGACGCAGAATGatCCCTTGCAGGACCATACGGACGATGGCTTGCCTGAGTATTTGTGTGGCGAATGCCTGCACAAGCTTGAAGCTGCCTATGCTTTTGTGTTGCAGGCGCGGCAGGCGCAGGAGCAActattgctgcagctgcgcaaaGGTTCGCAAAGGCAGTGCTTGGAGGAGATGCCCATAGACATCAGGATGCAGGACATTAAAAACGAAACGGACATTGACTTAGATTCGGAGCCAAATAAGAAAACCAAAAGCGAGTCGGTACTGGAAGATGCGGGAGAAGTTGAAGAACAAGAGATTGCTGCAGTGTCTGGTCCTGCCCTAAAATGGCAACCGGAAAGCGATAGCGACAATACTAAGGCGGGTGTTGACGAGCAGGACATGGACTTAAAGCCAAAGCAATTGCGGCGCAGCTTACGGAAAGCCAAACATGGTATAGTCAGCGAAAATGAAGCCtcTTTTGTTAATATAAAAACCTTGACTGCCAAGCGTCGTCGCGGACGTCCCGCGCGTCATCCCAATAAAGGAAACATCAACGAGGAGGGCCGACATACGTGCCAGGTGTGCGGGAAGACATTTTCGTGGCACCGCGACATGGTACGCCATGCCCGCATACACTTCGAGCAGGCGGCCTACGTGTGCGACAGCTGCGGCAAGAGTTTTTTGCGCAAGGACAAGTATATGTTTCATCTGCGTTCGCACGAGAAGCGTGCAGCAAAATGGCAGGCGCTGCAGTTGAGTAGTGAATGGCGGTTTGCAGAGCGCCTCTACAGCTCGGGCCGGCTCAAACATGTGATCTGCAAGCTGTGCGGCTTAAAGTGCCAGCGCATTCAGGAATTACGCGATCATTTGGCGTGCCATGCCAGCATTGAAACGTTGTCTAAATTGAGCATGGAAAGTGATGTGGTCAAAGAGCAGTTTgccaacgagcagcagcaattggacTTGGTACAGATCAAGCAACAGGTGTGCGCTGACATTGCCAAGGGACGTGAGCTGCTGGACAACTATTGCGCTGTGGTCAATGCGTATGGTTATGAGCTTTGCCTCAGCGACTCGGATGAGGAGCTAGCTGACTTGACGCCACAGTACCGGTGTCTGCCATGCAACACCACCTTTACACGCAAATATCGCGTTATGCGCCACACTCTGGAGGAGCACACGCATTCGGAAGCGGACGTACCATGGCAACGTTGTAATGTTTGTCAAATTGGCTTTGTGTGCGCCaagctgctggagcagcatCAACGCACGCAGTGCCACAATAAACTTAAGCGTTATAGCTGCCCCAATTGTCCAGGAAAATTCATTTGGAAGCAGAATTTGAAGCAGCATGCGTGCTCCCAACGCAGCGGGGTGCAaaaggagcaacagcaacagaaggTCGCCCATCAATTCCAATGTTGTCTCTGCGACGCCCAACTACACAGCATGGGAGGATTACGCTCTCATTTACTCACCCATCGCGATGGAAGCAGTGGCATAGATCCGGAGAAGCGGGCTGCCTTCTTTCGCACCTATTATCCCGATGGCTTTACCTGCAGCTTATCACAGCTGAGCGCACGCATTGCCGGCGACTTTGAGGCAGAGGATTATGGACGCTACTTCAATGCCAGCACTAGCAGTGGGCAGGAGCTGGATTTTTTTGACTCGGAGACAGATTTCAGTGATGAGGATCATTTGAGCTCTGTAGCTACGCTGCATATATGTTCACTGTGTGGCGAGACCACAATACGCCGGACACAGCTGCTTGAGcatcagcagcaccagcatAGTGAGGCTAGGCTGCCGCATGCCTGCGAGGACTGCGACATGAGCTTTGTAGCTGATTCCTTACTGCAATGGCATCGCCGACGTATTTGTGCCAAACGGCATGCCAAGTATCATTGCCAGTTTTGCAGCCAGCGTTTTTACTGGCATTCTAACTATGAGCTGCATttggagcagcagcacgcGAAGAAGGATAAAACAGAGGTTACCGAAGAGCAGGAGCCCAGATTAAAAAGCAAGCGCCATCCAACAGCAGCCAAGCTGCAGTGTGGCGAGTGCGAAAAGGTCTTCATCTGGCCCAAGGATCTGACACGTCACAAGCGCCTGCATCAGCCGCAGGCGTTGGCTCAGTATGAATGCGCCCACTGTGCGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCATATGCGCGTGCACGGTGAACAGCAGCTGGACGGAACGATTGCCAGTGATCAACCATCGTCCGTTCTGCAGCACATGCCGGTAGTGTTGACCCAACTTTGCCGGCCCAATGGTTGCAAGCAGATTCAGTGCATGATTTGCCTTTCGCAGCACACAAAAATCGCCGATCTGCGAGCGCATTTACTCAACCATCAGTTTACAGTGTTGTTTGCGGATGATCGCGGTAAGTCGGAGAGCATTGCAAACATTTCACGTGCTCTATATCCAGAGCTAACCACGCCGCTAGATCAACAACAGCTGGTCAGGCGCATTCAAAGCGATGTAGCCAAGGGCCTCGAACTGGAAAGATTCATTTCCATTACCAACGAGGCGGGCATTGAGCTCAGCTTGGACAGCAGCGAGACTGAAACAGATTCTGACTCTGCCGAGGCAGTTGGAAGCAGCAACGGGCGTCTCTACAATTGTGATCTTTGCCAGCTGAAGGTGCAGCGCAAGTATCAGCTTTACGCCCATCAGTTGGAGCAGCATACGTGGCAGCAGGCGACTCGTGTTTGCACATATTGCCAGGCTAGATTCGTGaatgagcagctgctggagcatCATTATCGCACGGTCTGCCGAAACGCGCTGCGGCGTTTTCTATGTCGAAAGTGCCCATTGCGCTTTCGCTGGCGCGAGAATCTGAAGCTACACACAGACGTAGCGCACCAAGAGTCAAGTGAAGAGCATTTGAACCTGGGCATTCAATTGAACGGCACACATTTGCTGCCTATTGTTAGCTATGACTGCACCGAATGCAATCGCagctttaaaatgcaaaaagatCTCACCAGGCACACTTTGATGCATGCCCAAGAGTCGAGCATTTACCGTTGTCGCTGGTGTGCTCGACGTTTCTATCGCCAGGCCAATCTTCTGCAGCATATCGAGCGTCATGGCATTAGCCCCGAGCAGCTGCCCTATGCGGAAGCGCTGCTCAATGCCAGCCGGAATCCGCATGGCAAGAAGTGCATCCAGTGCAAGGTGTGTAATATATCCTACCCCACTATTGCCGCACTACGCGCCCATCTGCAGTCTGCTCCAGGAGGCACACATCATGAGCTTGACTCGATGCTCAACTACTCTATAACCAACCAGCTGGGAtacgagctgcagctggacgaTTCGGAAACAGATGAGGAGGACAAGCCGCCGGGCACACCCCCACACTACACCTGCGGTATGTGCCAATTGCGCTGTGTGCGCAAGTTTGAGctgcatcagcatcaacaggcTATGCATCGACTGGAGCGCATCAGCAACGGTTGCGatctttgcatatttaaaagcGTCTCTCCAGATCTTATCCACTATCATCGTCGTGCGCTGTGTGACAACACAGAGAAAAAGTTCAAATGCATCAAGTGCGGCTATAAGTTTATGTGGGAGGCGAATCTGCTGCAGCACGTGAAGCTGGAGCATCCCAGTAGCGAGCTGCAGCAGGAAGTGACTTCCATGCTCACAACGGAGACTTCCAGTACTGAGTGCCAGATCTTTCAGTGCGGTCAGTGTCCAAGTAAATACAATCGCAAGGATCGTCTCACAGCACACGTAAAAAAATATCATTCAGCAGAAAATAGCTCCAAGGGTGCCCCAACAAGGACTTCAACAGGCGCCAAGCAGCAGAAAAGTTTTCTCTGTGCGTTCTGCGGCAAAGCGGTTAGTTCCTCATCCAATCTGATCATACACATACGTCGGCATACCGGCGAGAAGCCTTTCAAGTGCGACTACTGCGACATGGCGTTTCCACGGTCCTCCGATCTGCAGTGCCATCGACGCACCCATACGGGCGAGCGGCCGCATGTCTGCACCGTTTGTCAGAAGGGCTTCGCGCGCTCCtacaagctgcagcagcacatgCGCATCCACAATGGCGAACGCCCCTACAAGTGTACCTATTGTGATAAGAGCTTCACCCAGTCGAATGACCTGACGCTGCACATACGACGGCACACGGGCGAGCGTCCCTATCAGTGCAACACGTGCGGCGAGCGTTTTATTCAGGGCACAGCGCTTAAGAATCATCGACTACAGAATGGACACTACGAGACGGAAGCAGACCAAGTAAAAGATGTCTAA
Protein Sequence
MLPTNICRTCALQNDSLLPLATPTNIYDNKSLSDILHELTQNDPLQDHTDDGLPEYLCGECLHKLEAAYAFVLQARQAQEQLLLQLRKGSQRQCLEEMPIDIRMQDIKNETDIDLDSEPNKKTKSESVLEDAGEVEEQEIAAVSGPALKWQPESDSDNTKAGVDEQDMDLKPKQLRRSLRKAKHGIVSENEASFVNIKTLTAKRRRGRPARHPNKGNINEEGRHTCQVCGKTFSWHRDMVRHARIHFEQAAYVCDSCGKSFLRKDKYMFHLRSHEKRAAKWQALQLSSEWRFAERLYSSGRLKHVICKLCGLKCQRIQELRDHLACHASIETLSKLSMESDVVKEQFANEQQQLDLVQIKQQVCADIAKGRELLDNYCAVVNAYGYELCLSDSDEELADLTPQYRCLPCNTTFTRKYRVMRHTLEEHTHSEADVPWQRCNVCQIGFVCAKLLEQHQRTQCHNKLKRYSCPNCPGKFIWKQNLKQHACSQRSGVQKEQQQQKVAHQFQCCLCDAQLHSMGGLRSHLLTHRDGSSGIDPEKRAAFFRTYYPDGFTCSLSQLSARIAGDFEAEDYGRYFNASTSSGQELDFFDSETDFSDEDHLSSVATLHICSLCGETTIRRTQLLEHQQHQHSEARLPHACEDCDMSFVADSLLQWHRRRICAKRHAKYHCQFCSQRFYWHSNYELHLEQQHAKKDKTEVTEEQEPRLKSKRHPTAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYECAHCARKFHRKDGLKSHMRVHGEQQLDGTIASDQPSSVLQHMPVVLTQLCRPNGCKQIQCMICLSQHTKIADLRAHLLNHQFTVLFADDRGKSESIANISRALYPELTTPLDQQQLVRRIQSDVAKGLELERFISITNEAGIELSLDSSETETDSDSAEAVGSSNGRLYNCDLCQLKVQRKYQLYAHQLEQHTWQQATRVCTYCQARFVNEQLLEHHYRTVCRNALRRFLCRKCPLRFRWRENLKLHTDVAHQESSEEHLNLGIQLNGTHLLPIVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISPEQLPYAEALLNASRNPHGKKCIQCKVCNISYPTIAALRAHLQSAPGGTHHELDSMLNYSITNQLGYELQLDDSETDEEDKPPGTPPHYTCGMCQLRCVRKFELHQHQQAMHRLERISNGCDLCIFKSVSPDLIHYHRRALCDNTEKKFKCIKCGYKFMWEANLLQHVKLEHPSSELQQEVTSMLTTETSSTECQIFQCGQCPSKYNRKDRLTAHVKKYHSAENSSKGAPTRTSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYETEADQVKDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00563306;
90% Identity
iTF_00551040;
80% Identity
-