Basic Information

Gene Symbol
ztf-16
Assembly
GCA_008042475.1
Location
VNJM01002618.1:46161-50013[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 9.6e-05 0.0076 16.7 1.0 1 23 193 215 193 215 0.98
2 6 0.00028 0.023 15.2 4.2 1 23 221 243 221 243 0.98
3 6 0.0012 0.093 13.3 0.9 1 23 249 272 249 272 0.94
4 6 4.8 3.9e+02 1.9 0.8 2 22 281 301 280 303 0.86
5 6 0.13 11 6.8 0.3 2 19 701 718 700 720 0.91
6 6 0.11 9 7.0 0.2 2 22 729 749 728 752 0.89

Sequence Information

Coding Sequence
ATGGCCGAAACTCTCAGCTCGGCGGCCAGCAGTATGGAGCTGGCCTTGAAGGACACCAGCCCCACAGTCGGTGGCGGCATCATTGTGGACATGACGCCCACCACGGCGGCCCTGCTCCACCACAACGCGATGGCGCTGCGTAGCCTCAAGGAGGCGGCCTCGTCCGCCTCCGCCTCGGAGTCGGAACTGCAGGAGCCACGTTCGCCGACACCCACGCCCACGAATCTCAGCACCGGGCCGCACTCGCCGCCCATGACGTTCCGCTGCGAGCGTTGCGACAGTTTCGAGACCAGCTCACGCGCCTCCCTGCTGCTCCACGTCGTCCAGTGCCTGGCGGGTCAGgccgcggcggcggctgcagtGGCGGCACGCCTCAAGAGCGAGGATCTTCGCGGCGAGGAGCCGGAGAACATGAGCCTGGGCCACATGGAGGGCGGCGGCAAGGGCCAGGGGGAGACGGGCAACGGTTCCAGCTCCTCGGCCAGCTCATCGCCGGCCGGCAatagtggcggcggcggcggaggaagtggcggcggaggaagtggcggcggtggcaacaGCAGCTCCCGCAAGGTCTTCGAGTGCGATGTGTGCAACATGAAGTTCTCCAACGGCGCCAATATGCGACGCCACAAGATGCGGCATACGGGCGTGAAGCCCTACGAGTGCCGGGTGTGCCAGAAGCGCTTCTTCCGCAAGGATCACCTGGCGGAGCACTTCACCACCCACACGAAGACGCTGCCGTACCACTGCCCGATCTGCAACAGGGGCTTCCAGCGCCAGATCGCGATGCGCGCCCACTTCCAGAACGAGCACGTGGGCCAGCACGACCTGGTGAAGACGTGTCCGCTGTGCAGTTACCGGGCCGGCTCGATGAAATCCCTGCGGATTCACTTCTTCAATCGGCACGGCATCGATCTGGACAATCCCGGACCGGGTGGCACCTCTTCCCTGCTTCTGGCTCTCGAGTCGCAGgcctcggcggcggcggcagcagcagcagccagctaCGTCCCTCCAGGACTCAGTCCCGTTCCGGTGCAATCTcaatcccagcagcagcagcatcagccgcCAGCGGTGCCGCCTCCGGCCAGCGATAGTGGGGAGTCGATGCGATCCCTGGAGAACGCCACGCCCCCGATGCACTTCCTCACGCCGCACGTGGAGATCTCGACGCTGGGCGACAGTGGCAACACGGAGCTCTTTAATCTGATTTGCGTTTGGCGTGAATCTGCATTACagggaaacaacaacaacaacaacaataacaactgtgttaccaacaataacaacattagtgggagcaacaacaacaacagcaataataataacaacagcaatagcagCTCGATTAGCAATGGAAATGGCGTCGAGTCCAATGGTGAGAAGGTGAAAGATCGCGCCCTGATTATGCAATCGCCGGTGGAGTTGCCGATGGATTGCAACACAAAGGCTACGCCCATCACGTCCAGCACCACAGCCTCCAGCCTGAGTGCGAGTCTCAAGAGCCACCACCAGCATTCGCATCAACACCCGCACCTGCAGCATCCGCATTcgcatcaccatcatcaccacgAGAATCACATAACGCCGTCGATCAGTCTGATACCCATCAAGCAGGAGCCCATGGCCGAGGATGTGGACAAGAAGGACCTGATGAATGGCAGTGATCCCAACAGCGACACCGAGCAGGcttccaacaacaacaacaatagcaacagcagcaacaacaacaacagaatcaCCTCACTGATCAAGGTCTCGCCACTGAAATCGCTCCTGCGCGAGGATCTTAAGCGACGCATCTGCGCCAAGGCCAACAACCGGATCACCCGGAATGCCACACCGCTGgatagcagcaacaacaacaacaacaacaatagtgTGCTGTCCAACAGCCTGAGCAATGGCTCCGGCACCGGATCTTCCGGTGTTAATGGCGGCTCCGCCGGCACCGGAACCGGAGGCAGCGGTGGCCCACCGGCGCCGGCAACTCCAAGTGCCGGCAACGGCGCCAACTCAACGCCCATCTGCAACGGAACGATCACGTCGACCGGCCAGGATGGCGATCTGATGCTGAACCGCAAACTGATCCTCACCTGCCACTTCTGCGGGATCGAGTTCCCCGACGAGACGCTGTACTTCCTGCACAAGGGCTGTCACTGCGAGAGCAATCCGTGGCGGTGCAACATCTGCGGCGAGCAGATGAACAATGTCTACGAATTCAATGCACATCTGCTGAGCAAGAGCCACCAATAG
Protein Sequence
MAETLSSAASSMELALKDTSPTVGGGIIVDMTPTTAALLHHNAMALRSLKEAASSASASESELQEPRSPTPTPTNLSTGPHSPPMTFRCERCDSFETSSRASLLLHVVQCLAGQAAAAAAVAARLKSEDLRGEEPENMSLGHMEGGGKGQGETGNGSSSSASSSPAGNSGGGGGGSGGGGSGGGGNSSSRKVFECDVCNMKFSNGANMRRHKMRHTGVKPYECRVCQKRFFRKDHLAEHFTTHTKTLPYHCPICNRGFQRQIAMRAHFQNEHVGQHDLVKTCPLCSYRAGSMKSLRIHFFNRHGIDLDNPGPGGTSSLLLALESQASAAAAAAAASYVPPGLSPVPVQSQSQQQQHQPPAVPPPASDSGESMRSLENATPPMHFLTPHVEISTLGDSGNTELFNLICVWRESALQGNNNNNNNNNCVTNNNNISGSNNNNSNNNNNSNSSSISNGNGVESNGEKVKDRALIMQSPVELPMDCNTKATPITSSTTASSLSASLKSHHQHSHQHPHLQHPHSHHHHHHENHITPSISLIPIKQEPMAEDVDKKDLMNGSDPNSDTEQASNNNNNSNSSNNNNRITSLIKVSPLKSLLREDLKRRICAKANNRITRNATPLDSSNNNNNNNSVLSNSLSNGSGTGSSGVNGGSAGTGTGGSGGPPAPATPSAGNGANSTPICNGTITSTGQDGDLMLNRKLILTCHFCGIEFPDETLYFLHKGCHCESNPWRCNICGEQMNNVYEFNAHLLSKSHQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00605195;
90% Identity
iTF_00480511;
80% Identity
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