Basic Information

Insect: Drosophila kanapiae
Gene Symbol: -
Assembly: GCA_008042475.1
Location: VNJM01001954.1:293539-297441[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8e-05 0.0064 16.9 0.4 1 23 173 196 173 196 0.96

2 14 0.0016 0.12 12.9 3.1 2 23 245 267 241 267 0.90

3 14 0.0068 0.54 10.9 0.8 1 23 357 380 357 380 0.93

4 14 0.0091 0.73 10.5 3.8 2 23 429 451 428 452 0.95

5 14 0.00061 0.049 14.2 0.4 1 23 518 541 518 541 0.92

6 14 1.8 1.4e+02 3.2 0.1 2 14 560 572 559 584 0.85

7 14 0.00062 0.049 14.1 3.3 2 23 592 614 592 614 0.96

8 14 0.048 3.9 8.2 0.7 1 23 706 729 706 729 0.95

9 14 4.6e-05 0.0036 17.7 0.3 1 23 763 786 763 786 0.93

10 14 0.0039 0.31 11.6 1.5 2 23 836 858 835 858 0.95

11 14 0.028 2.2 8.9 3.5 1 23 955 977 955 978 0.93

12 14 0.0019 0.15 12.6 1.4 1 21 1030 1050 1030 1051 0.95

13 14 3.2 2.6e+02 2.5 0.1 3 23 1083 1106 1081 1106 0.74

14 14 2.7 2.2e+02 2.7 0.3 1 12 1126 1137 1126 1150 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8e-05	0.0064	16.9	0.4	1	23	173	196	173	196	0.96
2	14	0.0016	0.12	12.9	3.1	2	23	245	267	241	267	0.90
3	14	0.0068	0.54	10.9	0.8	1	23	357	380	357	380	0.93
4	14	0.0091	0.73	10.5	3.8	2	23	429	451	428	452	0.95
5	14	0.00061	0.049	14.2	0.4	1	23	518	541	518	541	0.92
6	14	1.8	1.4e+02	3.2	0.1	2	14	560	572	559	584	0.85
7	14	0.00062	0.049	14.1	3.3	2	23	592	614	592	614	0.96
8	14	0.048	3.9	8.2	0.7	1	23	706	729	706	729	0.95
9	14	4.6e-05	0.0036	17.7	0.3	1	23	763	786	763	786	0.93
10	14	0.0039	0.31	11.6	1.5	2	23	836	858	835	858	0.95
11	14	0.028	2.2	8.9	3.5	1	23	955	977	955	978	0.93
12	14	0.0019	0.15	12.6	1.4	1	21	1030	1050	1030	1051	0.95
13	14	3.2	2.6e+02	2.5	0.1	3	23	1083	1106	1081	1106	0.74
14	14	2.7	2.2e+02	2.7	0.3	1	12	1126	1137	1126	1150	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGATCTGTGGACGTCGATGTTCTCCTCCGAGTTCGACGATGGCGAGCCGGAAGGTGGTGGCGAGGGCGAGCTGCTGGAGGGTGGCGAGGATGGCACGCAGTTCGGCAATGGAAATGGTGACTTTCTCGACGACACGGCGATTCTGGAGGCTGGAGATGGAGTCGACGATCTGCTGGACGGCGAGGACGGTGagcgcgaggaggaggacgaacTGGATGGGTCTGAGAAGGGGTCTAAGGGACCTGAACCCGACGACGatgctctctttgatttcgAACTGGAACCCATTGTGAATATTGGGGAATCGCAGCCAACGACGGCCGGAGCGGTGCTGGCTCCCGCCGGTCCTATGGGCGCCAGCCAAGTGCGTCCCGCCCTGCAGCGGCACTCACTGCCTGCACTGAGCCGGCCGCGATCCATTGCGTTCCCCGTTCGGCCAACCACCTCACAGATCAACGCCACCGATGAGAACGGCGTGCCCATCAACTACGAGCTGGGCGTGGTGTACATCTGCCCAGCATGCGGCGGAGAGTTCCGGCAGCAGGATCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACTCTGCGCGGCCTCAACTTTGCGCCGCTGGACAAGCTGTACCAGCGCTGCAAGGAGTGCCACAAGCGCATCGCCATGCACAGTCGGGAGAACCTGCTGAAGCACAAGTTCACGCACCTGCCCTTCAGGTGCACCAAGTGTTACATCTGCAAAAGGGAGTACAAATACAGACAAGATCTAATGGTGCACTTGCGCATGGTGCACAGCGACGAAGTGGTGGCCATGATGCGGGAGGGTTACAATGCAGCCGGACGCAAGACCCGGGTTAGGGAATCTCGCaccgagcagctgcagcgggcGAAGAGCTTTCTCGAGGATGAGGATCGCATCGAGGTGCGGAACGAGCTGCTCGAACCGGATTTGGATGAGTCTGGCGGCGGCATGGAGCAGCAGTCGCTGGAGGAGCCGCTCAGTAAGAAGCGACCTGGAGGTGAAGGAGAAGCCACCGAGCTATGCGAGGATTACATTCACTATATGTGCCCCGACTGCGGCACCGAGTGCGACACCCATGCCCAGTGGAGCCAGCACATAGAGTTTGTCCATGATTACGTGAGTCGGCGGGGACTCAACTTCCGGAGCGTCGACATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTCACCCCGAACACCATCAAGTCGCTGCGCGCTCACAAATTCAGTCACTTGTCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGATCACCAGGAACTCGTGCGGCACTTGCTCAAGCAGCATCATATGGAGACGCTGATTTCGGAGAATGACGCCGAGAATGAGGATGGAGAGGTGACCCTTCCGGTTGACGACTGCCAAGACAATGAAAACGGCGAGCGCAACGGCGCCGCCTTGGACGAGGATTCTCCCTACTTTGAGGACGCCCCCCGGCGTGGCGGTCGCATCAGCAGCGATGACATTTTCGAGCCGCACATCGACTACCTCTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTGATGGCACACAGCATGAACGATCTGTCCAAGCTGAACTTCGAGATGATCAACGAACGGCAGCTGAAGTGCACCGAATGCGACAAGATCATCACGAATGCGTATGGCATACAGAATGCGCAGCAGCACAGGATCACCCACTTGCCGTTCAAGGCGTATGCCAGATGCCGCAAGTGCCACAAGTCCTACACGGACCGCAAGGGTCTGGTCAAGCATCTGGCCACCTATCATCGCATAGGCTGTGAGCCTCGGAAGTCGGGAGGAGGAGCACTAACTACGCCCAAGCAGCCCCGCAAGCAGATCGTGACGGTGGCCAATGAGACCTACGAGATTATCTACCTGGACGATGTGGAGCAGAGCAgcctggaggaggaggagaatgaCTTTGGTGAGCAAATGCTGGCGGATGAGGAGGATTACCCCATTGCTCCGGTGCCGCAGCAACAGCCCCGGCAATTGCCGCCTCCCCCACGACCCTCCTCCGTGCAGAACAACCAGCAGCGCTACAAGTGCGTCCACTGCAGCACCCTCTTTCCCACCCAGGTGGCTGTGCGGCTGCACATCAGCGAGAAGCACTGCCGGAAACCCAATCAGATGGGTCGCAGGCATCGCCACGCGCTCTCCAATTCCGGTGGCGCCGACTCCGGCCTGAATACCGTGGAGCAGAACTACATCTTCCTGTGCCCGTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGTCACATCAACGAGGAGCACAATTTCGGCAAGCGAAACTATCTGAACATGCGGCAGCTGGACAAGTATCGCTACCAGTGCACCCAGTGCAAGGACATTGTGTGCAACTCAAAGCTGAAGGGCCTGCAGGACCATCACTTCCGCCACCTGCCATACCGCCTGTATCTCAAGTGCCTGGTCTGCGGCACCTGCTACAATCACAAGCCCAACATAGCTGCCCATCTCAGGGCGCGGCACAACATCTACGATAGGGAGACGCCCCTGATGGTAACCAAACCCAAAAATGTGTACGGTCGGGGTAAGGATAAAGACATGGAGAAGGCAGCCTTAACAGCTCCcgcgccagcagcaggatcTCCACCCGGTTGCTCCTCTTcctcggcggctgctgctgctgctcctccttccgCAGTAAGTCGCACTCTCAAACCGCAACCCGGTGACCTGCCCACGCGACCCGCTGGCCTGAACACCCTGGAGGACAGCATCTCGTACCACAATGCCGTCGACATGGACTTCATCACGTACTTCTGCCCCAAGTGCAACCAGAACTTTGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCACCACAACTTTAACAGTCGCGAGGGCTTGAACTTCCGGCAGATCGATAACCATCACTACCTGTGCCTCGAGTGCTACAAGCGGGTGACCGTGACCCACACCAAGGGCGCCATTGGTCAGCTGCAGTCGCACAAGTTCCGTCATCTCCCCCATCGCTCCTTCAAGTGTCTCACCTGCGACGCCTCCTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAATCGCGACACCAACCGGTGTGACAATCGGCCCCAAAGGGAGCTGGATGAGGAGGAGCCCATCGAGGACACGCAGCTGCGCTCCATTTACCACCTGGCCTGTCCGCAGTGCGGCGATGACTTCAACACGCCCAGCAGGAAGCAGTGGCGCGATCACATCAATGTCTTTCACGGCCTCGCCTCGCTGGATCTGCTGCACATGCACAAGGTGAGCGAGGACGAGGATATCTATCGCTGCCAGGACTGTGACGAGGAGCTGCAGACGAACCGCCAGTGGGTGCTGCAATACCACCGCTTCCAGCATCTGCCACAGCCAGCCTACATCCGCTGCCAGCTGTGCGAGCAGAACAGTGAGCGGGATGCGACAGTAGCTTCCGGCATGCATAGTCTCCGggaactgcagcagcatctccgCAAGCATCATTCAACAGCAGTGGGCGAGGACGAGATGAGTGTGCTCCGCGAACAGATTGcccaggaggagaaggagcaggaggagattGTGGGCCTGGTGGCAGAGGAAGATGACAACCAGGCGGGTCAGGACTCCGCCGGGCCCTACATGCCGCTTCCGCCGCATTTATTGGACGATGGAGACGACGTGGAGTTTGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSEFDDGEPEGGGEGELLEGGEDGTQFGNGNGDFLDDTAILEAGDGVDDLLDGEDGEREEEDELDGSEKGSKGPEPDDDALFDFELEPIVNIGESQPTTAGAVLAPAGPMGASQVRPALQRHSLPALSRPRSIAFPVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHSDEVVAMMREGYNAAGRKTRVRESRTEQLQRAKSFLEDEDRIEVRNELLEPDLDESGGGMEQQSLEEPLSKKRPGGEGEATELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSHPEWLRCKLCYKGYTDHQELVRHLLKQHHMETLISENDAENEDGEVTLPVDDCQDNENGERNGAALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCEPRKSGGGALTTPKQPRKQIVTVANETYEIIYLDDVEQSSLEEEENDFGEQMLADEEDYPIAPVPQQQPRQLPPPPRPSSVQNNQQRYKCVHCSTLFPTQVAVRLHISEKHCRKPNQMGRRHRHALSNSGGADSGLNTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFGKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIYDRETPLMVTKPKNVYGRGKDKDMEKAALTAPAPAAGSPPGCSSSSAAAAAAPPSAVSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEHHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDEEEPIEDTQLRSIYHLACPQCGDDFNTPSRKQWRDHINVFHGLASLDLLHMHKVSEDEDIYRCQDCDEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQNSERDATVASGMHSLRELQQHLRKHHSTAVGEDEMSVLREQIAQEEKEQEEIVGLVAEEDDNQAGQDSAGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -