Basic Information

Gene Symbol
-
Assembly
GCA_008042475.1
Location
VNJM01003527.1:1014798-1020728[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0098 0.79 10.4 1.3 2 23 156 177 155 177 0.97
2 14 0.00051 0.041 14.4 2.1 1 23 399 421 399 421 0.98
3 14 2.9 2.3e+02 2.6 2.8 1 23 427 450 427 451 0.92
4 14 4.8 3.8e+02 1.9 2.1 1 23 473 496 473 496 0.91
5 14 0.0011 0.089 13.3 1.9 3 23 782 802 781 802 0.92
6 14 0.045 3.6 8.3 1.4 1 23 808 831 808 831 0.98
7 14 5.3 4.2e+02 1.8 0.8 3 23 869 889 867 890 0.84
8 14 0.0026 0.21 12.2 0.4 1 23 911 934 911 934 0.97
9 14 0.0017 0.14 12.8 0.3 1 23 1133 1156 1133 1156 0.90
10 14 0.0032 0.25 11.9 3.9 1 23 1167 1189 1167 1189 0.98
11 14 2.1e-06 0.00016 21.9 0.8 2 23 1195 1217 1194 1217 0.95
12 14 0.0034 0.27 11.8 1.3 3 23 1226 1249 1225 1249 0.87
13 14 4.9 3.9e+02 1.9 2.3 1 23 1254 1276 1254 1276 0.87
14 14 0.002 0.16 12.5 0.2 1 23 1282 1305 1282 1305 0.97

Sequence Information

Coding Sequence
ATGGCATTAAACAAACGGAAAAACGTGAACTTAGAAGCCCTAGCGGGCGTCAAGGAGGTGAACTACAAGTTTGCGTGTCGCTGCTGCCTAAAGGCGGACGCCGAGTTCGTAAAGCTGGAATCGGTGACTGTGGCGCGTAACCTGGACGCGGCCAGCGATGATGATAAAATTTCGCTCATGCGCTGCCTGCTCTTCTGCGTGCGCGCCGAGAATGCACCGGAGCTGCCGCAGTACATCTGCCTCGAGTGCAGCAAGAGCCTGCAGGTCACATACTACTTCCTGCAGAATGCGCTGCGTGCCAATGAGATCCTGTGCCGCACGCTGTGTCCCGCCAAGTTATCGGGTGCGGAGGGGAGGCGCATTAATGGTAGCTTGGGTCAGCGGTGGCAGCCATCGCCGTCACCCAAGGAGgcggcggcggcgacatcGGGGGACAGAACGAGGCCCCCAAAGAGCATGCGGCAAGAGTGCCAGGTGTGTGGCGCCATCTTCCACAGTCGATTGGAGTTCAAGCAGCACCTCCGCCAGCATGCAGATGGAAACTCCCACAACTGCAAGATGTGCAACTTTACAACGCTCAGACAGCGCCAGCTGCTGGAACACTATCGCTGCGATCACGCCATGACCCCCAGTCAGGCGGAGGAGCACGTAAAGGCGAGTCCCAAGCCGATACCGCCACCTAAGGAAGAAGAGATCAAGACAGTGTGCACGCTGGAGGACATGGAGCTGCTAATACCCACGGTCCTTACGCCGGACGACTATGCTCAGCCCACATTCGATTCGGATCAGCTGCGCGACATCGAGCAGCACCTGGCCGCCAGCATGGGCGAGACGGTGACCGAAATGGATACCCTTTCGTCCGCATTGCCGCCCATAGATACAACGCGGAATGTGAGCATCGGCACGGAGTATCTGGTGCTGCCGGATGGCACGCTGCAGCAGGTCAACGGAGGCGGCGTGGTAATTGAGTACATTGACGACAGCAAGACGACGCCGCCACCGGTCAATCCACCGCATGTGAACATCAACCTCCATAATCTCCTCAGCGGCCCCGACGAAAACGAGCCTATGGATATCGATGTCAACGAGCTAATTGTTGAGGATACATTGATAACGCATAAGCCCAGCATCTCCACATCCGTACCAGTTCCCgccaagccaaagccaaccGTTGGCGGTTCCCCCACTTTCAAGCATAAGTGCAGCATGTGCCCCCGGATGTTTTCGTCGGTGCCACGCCTGAAATCTCACCAGTTAACCCACAGCAATTTGCCCAAGTTCTTTTGCGACCAATGCGATTTCTACTCGCTGCGCAGTGTCGATCTCATCCAGCACTACAAGACCACACACCACCGCGTGGAAGAGAATGGTAGAATCAACAAGGTTCGAGCTACAGAATCGGAGGAGACGGGCATCTATTCGTGCGACATGTGCCTGTTTGAGACGCGCATCTGCAGTCAGCTGCGGGTTCACTACACGGATCAGCATGAGATCCAGCCCACGGAGGTGCAGCTGCGTCCCAGCTGGACGAATGAGGCAGAGCGCAGTGGTGGCCAAGGAGCGAAGAACAAGGCGCAGTCGGTCAGGCAGGCAAATCACGCCGACCTCCCGGTGGCCATTCAATATCCGCCAGTAGTTGCGGAAGTGCCAGTGCAAGTGCAGCAGCCaccggtggtggtggtggcggccaCCACATCAACAACGCACATCACACAAGGGAGCGACCACATAAACGTGGTGGTGGATACCACGCCGCTCTTCTATGCCTCCACCTCTGCCAGTGCGGTGCAGGCAGCACAGGCAGTGCCAGCGGTGCAGGCAATGCCTGAACTACCCCTGGTGACAACTGTGGGGGAGCAGCCCAACCAAGACATCACCACCGATGCCACCAATGCCAGCAATGCATTTGAAATCTTTCCCAAAAGCGACCCCCCACCCGATGAACAAATTCCGGCTGCCAACACATCAAATATCTCGATGTTTGGCGATATGCAGGATTTTATAGATAACACCGATGTGGCTGCCATATGCACGATACCGGCAGATGATATGCCCGTTGTGGATGGCGACGATATTGTGattgataataataacatcAGCCTGGACTTCGATGCGGAGAAGCTCTTTGAGGAtttcgaggaggaggaagatgcCGTGGCCGAAGATGAGGATGAAGACGAAGAGGATGAGGaaggagaggaggaggaagaggaggaggcggatAATGATGATGAGAATGACAACAATGATGCGGCCACAGATCAAAATTTGCTGCTAACCagcgacgatgatgatgtggACGACTTTGACGATGAACAATCGAAGCATCTGCAGAAGCCCTATTGCATTTATTGTAACAAGAAGTTCACCAGCCAGTACAAGTTCGAGAACCACATGTTTGTCCATCGGGGCCTGGCTCCCTATCGGTGCGAACTGTGCACCAACCTGTACAACATGAAGCGCCTGCTGATCAGACACTACAAGACCGTTCACAAGCGAATGCCCACCAGGGACATGGTACAGGCCAAGGGCGACAAGGTGCTGGTGGCCCGTAACAACATAGAGAAGCTCTATCTGGATGCTGTCAAGACTCCACTGGTCATGTGCGCCAAGTGTCCGTATGAGTGCGAGGCGGATGGAGAAATGCGAAAGCATCTAAATGCCCACCACGGCATCAATGATGGACTGTCCATTCATGCCAACGAGGTCTTTATCATACGCAAACTACCGTTCGAGTGCCCGCGCTGCATTCGATCCTTTGCTGCGAAGGGCACGCTCACCCGCCATCTGCAGCGCAGCCACTTGGTGGACACAATCATTGAGATGCAATCGCCGCAGTCATCGGCGGCCACCaccacaataacaacaacaacggccacAATATCCGGGCCAGCGGGAGATAAAGAACCCAATAAGGTGTTGCCGCCGGACGGGAGGGctgagatgatgatgatgtcgacggcgacgacggcTGCTGCAGGCAATGCAGAGTCGGGAGGAGACCaacatgatgatgatgatggagcaAAAAGCAAGCGTCGCGCCATTAccgaggaggatgtggatcCGGTGACATTGGACGCAGCCACtgcggcaacaacagctgccATAGAAGCGGCAATaacatccgcatccgtatcGCCCGCCGAAACAACAGCCTTAACATCCTCAGCCTCCAATCTGTATCCCACTCCCACGCCGTTCGATTTCGAGTATGACATAATAAGCAGCGATACGCAACGATCCCAGGTTTCAACACCCACCTCCAATGCCCAGCTTAGATCGCCTGGCAGCAGTCTACTTAATGGCAGCGACAAGCTGCTGACCACCGCCGCCATGTCGCCATTTCCGACAAAGGGTCTGCGCTCCACCAGGCGAAAGGCCAACAGCTCGATCTATGTGTGCAAGCTTTGCAATAAGTCCTTCGACGAGCTGGGCAAGCTGGTCAAGCACGAGACGGAGGTGCACTCGAATACGGAGCCCTCGCGATGGGGCCAGCACAAGTGTCCCATCTGCAGTACCAGCTACCGCACGCTGACGCTGCTCAAGTTCCACATGAAGCGGCACGTTAATAGAAAGTCGCAATGCAAGCTGTGTCCCAAGACCTTCGCCACCAGCACAGAACTGGAGCGGCACATGAAGGCCAAGCATTGTCGGGAGAAGACGTTCGGGCCGTGTGCGTTGGATGGTTGTGGTAAGATGTTTGCCTTCAAACATCACATGGTGCGGCATCAGAACGCCTCCCATTTGAAATCTCTGCATATTTGCGTCGTTTGTAACAAAGAGATGCTGAGCATGGCGCATCTGAAGAAGCACATGACACTGCACAAGGGCATGGTGTCCTACCAGTGTCCGGAATGCGACCGCCCATATTTGCGGCGCGGCAGACTTCAGAGTCATCTGCTAAAAATTCACAAGAAGCGCGTTAGCGACGAAGAGATGGCTGCCATCTTCCGCGACATAAAGGTGGCCACCGGTAGCGCCCACGAGCTGAAGGTGATGACCCGTAAGGGACAGCTGGGGCGCCTCAAGAAGAAGAACGAATCGGAAGACAAAGAGGGGACGGATCTAGATGCGGCAGAGTCAGCGACAGAGgaaacagcggcagcatcagcGACGGAGACAACAACGGCAGCGTCAGCGACGGAGGAAAAAGCGGCAGCAACGAAGGCAAAGGCAGCGACGGAAGAAacagcggcaacggcagcagaaATGTCCAAATAG
Protein Sequence
MALNKRKNVNLEALAGVKEVNYKFACRCCLKADAEFVKLESVTVARNLDAASDDDKISLMRCLLFCVRAENAPELPQYICLECSKSLQVTYYFLQNALRANEILCRTLCPAKLSGAEGRRINGSLGQRWQPSPSPKEAAAATSGDRTRPPKSMRQECQVCGAIFHSRLEFKQHLRQHADGNSHNCKMCNFTTLRQRQLLEHYRCDHAMTPSQAEEHVKASPKPIPPPKEEEIKTVCTLEDMELLIPTVLTPDDYAQPTFDSDQLRDIEQHLAASMGETVTEMDTLSSALPPIDTTRNVSIGTEYLVLPDGTLQQVNGGGVVIEYIDDSKTTPPPVNPPHVNINLHNLLSGPDENEPMDIDVNELIVEDTLITHKPSISTSVPVPAKPKPTVGGSPTFKHKCSMCPRMFSSVPRLKSHQLTHSNLPKFFCDQCDFYSLRSVDLIQHYKTTHHRVEENGRINKVRATESEETGIYSCDMCLFETRICSQLRVHYTDQHEIQPTEVQLRPSWTNEAERSGGQGAKNKAQSVRQANHADLPVAIQYPPVVAEVPVQVQQPPVVVVAATTSTTHITQGSDHINVVVDTTPLFYASTSASAVQAAQAVPAVQAMPELPLVTTVGEQPNQDITTDATNASNAFEIFPKSDPPPDEQIPAANTSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAEKLFEDFEEEEDAVAEDEDEDEEDEEGEEEEEEEADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVARNNIEKLYLDAVKTPLVMCAKCPYECEADGEMRKHLNAHHGINDGLSIHANEVFIIRKLPFECPRCIRSFAAKGTLTRHLQRSHLVDTIIEMQSPQSSAATTTITTTTATISGPAGDKEPNKVLPPDGRAEMMMMSTATTAAAGNAESGGDQHDDDDGAKSKRRAITEEDVDPVTLDAATAATTAAIEAAITSASVSPAETTALTSSASNLYPTPTPFDFEYDIISSDTQRSQVSTPTSNAQLRSPGSSLLNGSDKLLTTAAMSPFPTKGLRSTRRKANSSIYVCKLCNKSFDELGKLVKHETEVHSNTEPSRWGQHKCPICSTSYRTLTLLKFHMKRHVNRKSQCKLCPKTFATSTELERHMKAKHCREKTFGPCALDGCGKMFAFKHHMVRHQNASHLKSLHICVVCNKEMLSMAHLKKHMTLHKGMVSYQCPECDRPYLRRGRLQSHLLKIHKKRVSDEEMAAIFRDIKVATGSAHELKVMTRKGQLGRLKKKNESEDKEGTDLDAAESATEETAAASATETTTAASATEEKAAATKAKAATEETAATAAEMSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569958;
90% Identity
iTF_00569958;
80% Identity
-